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The map label for this gene is infC

Identifier: 218905802

GI number: 218905802

Start: 4442359

End: 4442859

Strand: Reverse

Name: infC

Synonym: BCAH820_4690

Alternate gene names: 218905802

Gene position: 4442859-4442359 (Counterclockwise)

Preceding gene: 218905803

Following gene: 218905801

Centisome position: 83.79

GC content: 38.32

Gene sequence:

>501_bases
ATGATTAACGAGCAAATTCGTGCACGTGAAGTACGTTTAGTTGGCGCAAATGGCGATCAACTTGGAATCAAGTCTCGTAA
TGACGCTTTAGACTTAGCTGCAAATCTTAATCTTGATTTAGTATTAGTTGCTCCAAATGCGAAACCGCCAGTATGCCGCA
TTATGGACTACGGTAAATTCCGCTTTGAGCAACAGAAGAAAGAAAAAGAACAGCGCAAAAATCAAAAAGTAATTAGCATG
AAAGAAGTTCGTTTAAGTCCAACAATTGATGAACACGACTTTAACACAAAACTTCGTAATGCTATCAAGTTTTTAGAGAA
AGGCGACAAGGTTAAAGCGTCAATTCGCTTTAAAGGACGTGCCATTACTCATAAAGAAATCGGTCAACGTGTTTTAGATC
GCTTCTCAGAAGCTTGTGCTGAAGTTAGTACAATCGAATCTAAGCCTAAAATGGAAGGACGCAGTATGTTCTTAGTTTTA
GCACCGAAAAACGATAAGTAA

Upstream 100 bases:

>100_bases
GTGTGGGTGTCGTATGCCCGCACTTTTTTTGTCGGGTTCTATGACTACAAACTATGTTCTGAGAAAACCTTGGAGGTGGC
TTACTATTAGCAAGGATATG

Downstream 100 bases:

>100_bases
TAGATAGAGGAGGAAATACCTATGCCTAAACAAAAAACTCATCGCGGCGCTGCAAAGCGTTTCAAAAAGACTGGATCAGG
TAAACTGAAACGTTCTCACG

Product: translation initiation factor IF-3

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 166; Mature: 166

Protein sequence:

>166_residues
MINEQIRAREVRLVGANGDQLGIKSRNDALDLAANLNLDLVLVAPNAKPPVCRIMDYGKFRFEQQKKEKEQRKNQKVISM
KEVRLSPTIDEHDFNTKLRNAIKFLEKGDKVKASIRFKGRAITHKEIGQRVLDRFSEACAEVSTIESKPKMEGRSMFLVL
APKNDK

Sequences:

>Translated_166_residues
MINEQIRAREVRLVGANGDQLGIKSRNDALDLAANLNLDLVLVAPNAKPPVCRIMDYGKFRFEQQKKEKEQRKNQKVISM
KEVRLSPTIDEHDFNTKLRNAIKFLEKGDKVKASIRFKGRAITHKEIGQRVLDRFSEACAEVSTIESKPKMEGRSMFLVL
APKNDK
>Mature_166_residues
MINEQIRAREVRLVGANGDQLGIKSRNDALDLAANLNLDLVLVAPNAKPPVCRIMDYGKFRFEQQKKEKEQRKNQKVISM
KEVRLSPTIDEHDFNTKLRNAIKFLEKGDKVKASIRFKGRAITHKEIGQRVLDRFSEACAEVSTIESKPKMEGRSMFLVL
APKNDK

Specific function: IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins

COG id: COG0290

COG function: function code J; Translation initiation factor 3 (IF-3)

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the IF-3 family

Homologues:

Organism=Escherichia coli, GI1788012, Length=163, Percent_Identity=53.9877300613497, Blast_Score=166, Evalue=8e-43,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): IF3_BACAN (Q81L15)

Other databases:

- EMBL:   AE016879
- EMBL:   AE017334
- EMBL:   AE017225
- RefSeq:   NP_847022.1
- RefSeq:   YP_021465.2
- RefSeq:   YP_030718.1
- ProteinModelPortal:   Q81L15
- IntAct:   Q81L15
- EnsemblBacteria:   EBBACT00000012731
- EnsemblBacteria:   EBBACT00000018781
- EnsemblBacteria:   EBBACT00000023613
- GeneID:   1083958
- GeneID:   2815793
- GeneID:   2851577
- GenomeReviews:   AE016879_GR
- GenomeReviews:   AE017225_GR
- GenomeReviews:   AE017334_GR
- KEGG:   ban:BA_4819
- KEGG:   bar:GBAA_4819
- KEGG:   bat:BAS4471
- TIGR:   BA_4819
- TIGR:   GBAA_4819
- GeneTree:   EBGT00050000001839
- HOGENOM:   HBG744268
- OMA:   APKAPIN
- ProtClustDB:   PRK00028
- BioCyc:   BANT260799:BAS4471-MONOMER
- BioCyc:   BANT261594:GBAA4819-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00080
- InterPro:   IPR019813
- InterPro:   IPR001288
- InterPro:   IPR019815
- InterPro:   IPR019814
- Gene3D:   G3DSA:3.10.20.80
- Gene3D:   G3DSA:3.30.110.10
- PANTHER:   PTHR10938
- TIGRFAMs:   TIGR00168

Pfam domain/function: PF00707 IF3_C; PF05198 IF3_N; SSF54364 IF3; SSF55200 IF3

EC number: NA

Molecular weight: Translated: 18949; Mature: 18949

Theoretical pI: Translated: 10.54; Mature: 10.54

Prosite motif: PS00938 IF3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MINEQIRAREVRLVGANGDQLGIKSRNDALDLAANLNLDLVLVAPNAKPPVCRIMDYGKF
CCCCCCCEEEEEEECCCCCEECCCCCCCCEEEEECCCEEEEEECCCCCCCEEEEECCCHH
RFEQQKKEKEQRKNQKVISMKEVRLSPTIDEHDFNTKLRNAIKFLEKGDKVKASIRFKGR
HHHHHHHHHHHHHCCCCEEHEEEECCCCCCCCCCHHHHHHHHHHHHCCCCEEEEEEECCC
AITHKEIGQRVLDRFSEACAEVSTIESKPKMEGRSMFLVLAPKNDK
CCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEECCCCC
>Mature Secondary Structure
MINEQIRAREVRLVGANGDQLGIKSRNDALDLAANLNLDLVLVAPNAKPPVCRIMDYGKF
CCCCCCCEEEEEEECCCCCEECCCCCCCCEEEEECCCEEEEEECCCCCCCEEEEECCCHH
RFEQQKKEKEQRKNQKVISMKEVRLSPTIDEHDFNTKLRNAIKFLEKGDKVKASIRFKGR
HHHHHHHHHHHHHCCCCEEHEEEECCCCCCCCCCHHHHHHHHHHHHCCCCEEEEEEECCC
AITHKEIGQRVLDRFSEACAEVSTIESKPKMEGRSMFLVLAPKNDK
CCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12721629