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The map label for this gene is cisA [H]

Identifier: 218905694

GI number: 218905694

Start: 4335938

End: 4337404

Strand: Reverse

Name: cisA [H]

Synonym: BCAH820_4582

Alternate gene names: 218905694

Gene position: 4337404-4335938 (Counterclockwise)

Preceding gene: 218905695

Following gene: 218905693

Centisome position: 81.8

GC content: 35.11

Gene sequence:

>1467_bases
TTGAGTTCGTATGCTGTATATGTCCGTGTATCAACCGACCGTGATGAACAAATTTCTTCTGTTGAAAATCAAATAGACAT
TTGTCGTAACTGGTTGGAACGTAACGGTTTTGAATGGAACGAACAATGTGTTTATAAAGACGAAGGAATTAGTGGAACGT
TATTCACTGATCGTCCTGCAATTCAATTGCTTTTGCAAAAAGCTAAGACAAAAAAAATTAATATGGTGGTGTTTAAATCT
ATCTCTCGTCTTGCTCGTGATTTGAAGGATTCATTAGAAATTCGTGAAGTGTTTCTCGCTCACAATGTTCGAATTATCTC
TGTTGAAGAAGGATATGATTCCACTAAAGCTGGAAAGAATGATATGGCTTTTGAGCTCTGGTCGTTGTTTTCAGCTCAAT
ATAGCCGTACTCTATCTTCGAGTATTAGTGCAGCTTTAGCAGCAAAAGTAAGACGGGGAGAACATATTGGAAAAGTTCCA
TATGGGTACAATCGCGAGGATCAAAAATTGATAATAAATAAAGAAGAAGCTGAAGTTGTTCGGAATATTTATGGCTGGTA
CAACATTGGATGGGGATTCAAGCGGATTACAAATGAACTCAATCGATTGGGAATCAAACCAAAAAGTAAAGAGTTTTGGC
AAATGACATCTGTACAAAGAATTGTTCGAAGTCCCATTTACAAGGGTACTTTTATTTTAAATCAATATACATCGGTTAAA
GTTGGCGGTAAGAAGAAACAAATTCGAAACCCAAAAGAGAAGTGGTTTATTTTTCCTAAGCATCATCCAGCTATTGTAGA
TGAAGAAACTTGGAGCCGAGTAAATGAGAAGAATATAACGGATAATAAAACAAAAATTACAGCTTGGAATGAATTTCGTA
ATTTAGCAAAATGCGCAGTCTGTGGTTCAAATATGGTGATTGTACAATCCCATCTTCGAAAGAAGAGTGGTGAACGGAGA
GAATGGAAATATTTAAAGTGTTCACAGTACAGAAGGGCTGGGAAGCATGGTTGTGTAAATCATGTACCCATTCAATATCA
TGATTTTCGGCAGTTCATTATTGATTTGCTAGTGAAAAAAGGAGAGTCGGTCAATTTAAAGCTTCAGAGTAATGTCGAAG
AGGGACAAGAAAAAAAGATAAAAAAGTTACAACAGCTTTTGAACGTGAACGAACAAAAGAAAAAAACACTACTGGATTTG
TATTTAGAAGAACTCATTAATAAAGAAGAATTTGAAAAAAAACGAAGTGATCTTGAAGCGGAAATCACGAAAGTGAGTCA
AGAGTTGTTTATCCTGCAACAGAATGATGTAGTACAAACAGATATTAAAACGATAAAAGAAGCTTTTGAGCAGTTACAGA
AACAAGAGCAAGATTTGTTTCATGTGTTTCAGAAGCTTATTCAAGAGATTATGATTCATCAAAACGGAACGGTTGATATT
ACATATACTTTTGAAGCTCCATTATAA

Upstream 100 bases:

>100_bases
ATGGAAGTAACGAAAAGTATGGAAAAATCCTGAAACCCCACATATATATAAATAAAAATGTGTAGTTGTATCATTCATGG
TCAAGGAGGGATTTGCTGAG

Downstream 100 bases:

>100_bases
GAAGGGGGTATATCCCTTCTTATTTTTATTGTGAGTAAGGTAGTGGTATGCTGAAATGTTTTATTAATAGATGTATAAAA
GGCGTTAGATTAGCTTATAG

Product: site-specific recombinase

Products: NA

Alternate protein names: Stage IV sporulation protein CA [H]

Number of amino acids: Translated: 488; Mature: 487

Protein sequence:

>488_residues
MSSYAVYVRVSTDRDEQISSVENQIDICRNWLERNGFEWNEQCVYKDEGISGTLFTDRPAIQLLLQKAKTKKINMVVFKS
ISRLARDLKDSLEIREVFLAHNVRIISVEEGYDSTKAGKNDMAFELWSLFSAQYSRTLSSSISAALAAKVRRGEHIGKVP
YGYNREDQKLIINKEEAEVVRNIYGWYNIGWGFKRITNELNRLGIKPKSKEFWQMTSVQRIVRSPIYKGTFILNQYTSVK
VGGKKKQIRNPKEKWFIFPKHHPAIVDEETWSRVNEKNITDNKTKITAWNEFRNLAKCAVCGSNMVIVQSHLRKKSGERR
EWKYLKCSQYRRAGKHGCVNHVPIQYHDFRQFIIDLLVKKGESVNLKLQSNVEEGQEKKIKKLQQLLNVNEQKKKTLLDL
YLEELINKEEFEKKRSDLEAEITKVSQELFILQQNDVVQTDIKTIKEAFEQLQKQEQDLFHVFQKLIQEIMIHQNGTVDI
TYTFEAPL

Sequences:

>Translated_488_residues
MSSYAVYVRVSTDRDEQISSVENQIDICRNWLERNGFEWNEQCVYKDEGISGTLFTDRPAIQLLLQKAKTKKINMVVFKS
ISRLARDLKDSLEIREVFLAHNVRIISVEEGYDSTKAGKNDMAFELWSLFSAQYSRTLSSSISAALAAKVRRGEHIGKVP
YGYNREDQKLIINKEEAEVVRNIYGWYNIGWGFKRITNELNRLGIKPKSKEFWQMTSVQRIVRSPIYKGTFILNQYTSVK
VGGKKKQIRNPKEKWFIFPKHHPAIVDEETWSRVNEKNITDNKTKITAWNEFRNLAKCAVCGSNMVIVQSHLRKKSGERR
EWKYLKCSQYRRAGKHGCVNHVPIQYHDFRQFIIDLLVKKGESVNLKLQSNVEEGQEKKIKKLQQLLNVNEQKKKTLLDL
YLEELINKEEFEKKRSDLEAEITKVSQELFILQQNDVVQTDIKTIKEAFEQLQKQEQDLFHVFQKLIQEIMIHQNGTVDI
TYTFEAPL
>Mature_487_residues
SSYAVYVRVSTDRDEQISSVENQIDICRNWLERNGFEWNEQCVYKDEGISGTLFTDRPAIQLLLQKAKTKKINMVVFKSI
SRLARDLKDSLEIREVFLAHNVRIISVEEGYDSTKAGKNDMAFELWSLFSAQYSRTLSSSISAALAAKVRRGEHIGKVPY
GYNREDQKLIINKEEAEVVRNIYGWYNIGWGFKRITNELNRLGIKPKSKEFWQMTSVQRIVRSPIYKGTFILNQYTSVKV
GGKKKQIRNPKEKWFIFPKHHPAIVDEETWSRVNEKNITDNKTKITAWNEFRNLAKCAVCGSNMVIVQSHLRKKSGERRE
WKYLKCSQYRRAGKHGCVNHVPIQYHDFRQFIIDLLVKKGESVNLKLQSNVEEGQEKKIKKLQQLLNVNEQKKKTLLDLY
LEELINKEEFEKKRSDLEAEITKVSQELFILQQNDVVQTDIKTIKEAFEQLQKQEQDLFHVFQKLIQEIMIHQNGTVDIT
YTFEAPL

Specific function: Putative site-specific recombinase having a very important role in sporulation. It probably plays a role in the recombination of spoIIIC and spoIVCB to form sigma K factor [H]

COG id: COG1961

COG function: function code L; Site-specific recombinases, DNA invertase Pin homologs

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 recombinase domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011109
- InterPro:   IPR006118
- InterPro:   IPR006119 [H]

Pfam domain/function: PF07508 Recombinase; PF00239 Resolvase [H]

EC number: NA

Molecular weight: Translated: 57140; Mature: 57009

Theoretical pI: Translated: 9.81; Mature: 9.81

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSYAVYVRVSTDRDEQISSVENQIDICRNWLERNGFEWNEQCVYKDEGISGTLFTDRPA
CCCEEEEEEEECCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEECCCCCEEEECCCHH
IQLLLQKAKTKKINMVVFKSISRLARDLKDSLEIREVFLAHNVRIISVEEGYDSTKAGKN
HHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEEECCCCCCCCCCC
DMAFELWSLFSAQYSRTLSSSISAALAAKVRRGEHIGKVPYGYNREDQKLIINKEEAEVV
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEEECHHHHHH
RNIYGWYNIGWGFKRITNELNRLGIKPKSKEFWQMTSVQRIVRSPIYKGTFILNQYTSVK
HHHHHHHCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCCCEEEEECCCEEE
VGGKKKQIRNPKEKWFIFPKHHPAIVDEETWSRVNEKNITDNKTKITAWNEFRNLAKCAV
ECCCHHHHCCCCHHEEECCCCCCCCCCCHHHHHCCCCCCCCCCEEEEEHHHHHHHHHHHH
CGSNMVIVQSHLRKKSGERREWKYLKCSQYRRAGKHGCVNHVPIQYHDFRQFIIDLLVKK
CCCCEEEHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHC
GESVNLKLQSNVEEGQEKKIKKLQQLLNVNEQKKKTLLDLYLEELINKEEFEKKRSDLEA
CCCEEEEECCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCHHHHHHHHHHHHH
EITKVSQELFILQQNDVVQTDIKTIKEAFEQLQKQEQDLFHVFQKLIQEIMIHQNGTVDI
HHHHHHHHHEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEE
TYTFEAPL
EEEECCCC
>Mature Secondary Structure 
SSYAVYVRVSTDRDEQISSVENQIDICRNWLERNGFEWNEQCVYKDEGISGTLFTDRPA
CCEEEEEEEECCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEECCCCCEEEECCCHH
IQLLLQKAKTKKINMVVFKSISRLARDLKDSLEIREVFLAHNVRIISVEEGYDSTKAGKN
HHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEEECCCCCCCCCCC
DMAFELWSLFSAQYSRTLSSSISAALAAKVRRGEHIGKVPYGYNREDQKLIINKEEAEVV
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEEECHHHHHH
RNIYGWYNIGWGFKRITNELNRLGIKPKSKEFWQMTSVQRIVRSPIYKGTFILNQYTSVK
HHHHHHHCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCCCEEEEECCCEEE
VGGKKKQIRNPKEKWFIFPKHHPAIVDEETWSRVNEKNITDNKTKITAWNEFRNLAKCAV
ECCCHHHHCCCCHHEEECCCCCCCCCCCHHHHHCCCCCCCCCCEEEEEHHHHHHHHHHHH
CGSNMVIVQSHLRKKSGERREWKYLKCSQYRRAGKHGCVNHVPIQYHDFRQFIIDLLVKK
CCCCEEEHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHC
GESVNLKLQSNVEEGQEKKIKKLQQLLNVNEQKKKTLLDLYLEELINKEEFEKKRSDLEA
CCCEEEEECCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCHHHHHHHHHHHHH
EITKVSQELFILQQNDVVQTDIKTIKEAFEQLQKQEQDLFHVFQKLIQEIMIHQNGTVDI
HHHHHHHHHEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEE
TYTFEAPL
EEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2105293; 7704261; 8969508; 9384377 [H]