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The map label for this gene is mreD [H]

Identifier: 218905645

GI number: 218905645

Start: 4287584

End: 4288129

Strand: Reverse

Name: mreD [H]

Synonym: BCAH820_4530

Alternate gene names: 218905645

Gene position: 4288129-4287584 (Counterclockwise)

Preceding gene: 218905646

Following gene: 218905644

Centisome position: 80.87

GC content: 32.6

Gene sequence:

>546_bases
ATGATGAAGATTTTAAAAAGAGCAGCTCTTCCTCTTTTGCTCCTTTTTATTTTTTTATTTGAAAATATGTTTGCTACTAT
TGTTCCAACAGAGGTTTTTTGGAAAGACAGTATAGCAGCACCTCATTTCTTTATCATTGTGTTATGTTTTGTTACTGTGT
ACTATAGTCCGGTCCAAGGGATTTATTACGGACTATTATTTGGTTTCTTATTTGATACCGTATACACAGAACTTGTCGGT
ATATATATTTTCGCGTATCCGATTGTAGCTTATTTAGTTTATAGTGTGATGAAGGTACTACAATTGAATTTATTTATTGT
TGTCTCTATCGTACTAGCTAGCATTGCAGCATTAGAGTATTATGTGTATGGATTTTTAACTTTGTTAGGACGTACTCATA
TGTCGGCGTATGTCTTTTTCACAGATCGTCTCCTTTCTACTTTATTGCTAAATGCAATTTTCTTATTCATAGTTTGTTTC
CCACTGAGACGATATTTAGTGCGTCTTTCAAAAGCGATGGAAGAAAAAGAAAAAAGGATTTTCTAA

Upstream 100 bases:

>100_bases
CTTATGTAAAACCTGCCGCTGATTTAAATGACGTAGAGCATATTATGGTTGCGAAACGTGCAACGCCTTCAGCGCCATTA
GAATAGGAGGGGGAGAAGAG

Downstream 100 bases:

>100_bases
TTTTATGTCGAATTGAATCGGTGGGGTGAACTTTAGTGGAAGAAAAAAAGCAACAAAATGTAACAATAAAAGGGACAAAA
GACGGAATAACGCTTCATTT

Product: rod shape-determining protein MreD

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 181; Mature: 181

Protein sequence:

>181_residues
MMKILKRAALPLLLLFIFLFENMFATIVPTEVFWKDSIAAPHFFIIVLCFVTVYYSPVQGIYYGLLFGFLFDTVYTELVG
IYIFAYPIVAYLVYSVMKVLQLNLFIVVSIVLASIAALEYYVYGFLTLLGRTHMSAYVFFTDRLLSTLLLNAIFLFIVCF
PLRRYLVRLSKAMEEKEKRIF

Sequences:

>Translated_181_residues
MMKILKRAALPLLLLFIFLFENMFATIVPTEVFWKDSIAAPHFFIIVLCFVTVYYSPVQGIYYGLLFGFLFDTVYTELVG
IYIFAYPIVAYLVYSVMKVLQLNLFIVVSIVLASIAALEYYVYGFLTLLGRTHMSAYVFFTDRLLSTLLLNAIFLFIVCF
PLRRYLVRLSKAMEEKEKRIF
>Mature_181_residues
MMKILKRAALPLLLLFIFLFENMFATIVPTEVFWKDSIAAPHFFIIVLCFVTVYYSPVQGIYYGLLFGFLFDTVYTELVG
IYIFAYPIVAYLVYSVMKVLQLNLFIVVSIVLASIAALEYYVYGFLTLLGRTHMSAYVFFTDRLLSTLLLNAIFLFIVCF
PLRRYLVRLSKAMEEKEKRIF

Specific function: Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins [H]

COG id: COG2891

COG function: function code M; Cell shape-determining protein

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mreD family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007227 [H]

Pfam domain/function: PF04093 MreD [H]

EC number: NA

Molecular weight: Translated: 21083; Mature: 21083

Theoretical pI: Translated: 9.15; Mature: 9.15

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMKILKRAALPLLLLFIFLFENMFATIVPTEVFWKDSIAAPHFFIIVLCFVTVYYSPVQG
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHH
IYYGLLFGFLFDTVYTELVGIYIFAYPIVAYLVYSVMKVLQLNLFIVVSIVLASIAALEY
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
YVYGFLTLLGRTHMSAYVFFTDRLLSTLLLNAIFLFIVCFPLRRYLVRLSKAMEEKEKRI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
F
C
>Mature Secondary Structure
MMKILKRAALPLLLLFIFLFENMFATIVPTEVFWKDSIAAPHFFIIVLCFVTVYYSPVQG
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHH
IYYGLLFGFLFDTVYTELVGIYIFAYPIVAYLVYSVMKVLQLNLFIVVSIVLASIAALEY
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
YVYGFLTLLGRTHMSAYVFFTDRLLSTLLLNAIFLFIVCFPLRRYLVRLSKAMEEKEKRI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
F
C

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 1400225; 1400224; 9384377 [H]