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The map label for this gene is comGA [H]

Identifier: 218905380

GI number: 218905380

Start: 4053263

End: 4054309

Strand: Reverse

Name: comGA [H]

Synonym: BCAH820_4264

Alternate gene names: 218905380

Gene position: 4054309-4053263 (Counterclockwise)

Preceding gene: 218905384

Following gene: 218905379

Centisome position: 76.46

GC content: 37.82

Gene sequence:

>1047_bases
ATGATGAATGGAATTGAAAGCTTTGCGAATATGATTTTGAAAGAAGCGTGCAGGGTACAAGCGTCGGACTTACATATTGT
GCCCCGGCAGAAGGATGTAGTGGTTCAGCTGCGTATAGGAAAAGATTTAATGACGAAATACTGTATTGAAAAGGAATTTG
GAGAAAAACTTGTTTCACACTTTAAATTTTTAGCATCTATGGATATAGGGGAGAGGCGGAAGCCACAAAATGGTTCACTG
TATTTACAAATGGATGGACAAGAAGTGTATTTGCGCCTTTCCACGCTTCCAACCGTATACCAAGAAAGTCTCGTTATTCG
TCTTCATTTACAAGCATCTATTCAGCCGTTATCTCATCTTTCGTTATTTCCAAGTACAGCGAAGATACTACTTTCTTTTT
TACGTTATTCTCATGGATTACTCGTATTTACTGGACCGACTGGTTCGGGGAAGACAACAACAATGTATGCATTATTAGAG
GTAATTAGAAAAAAGAAAACACGTCGCATTGTTACACTGGAAGATCCAGTTGAAAAAAGAAATGACGATGTATTACAAAT
TCAAATAAATGAAAAAGCAGGTATCACATATGAGGCTGGACTAAAGGCTATTTTGCGTCATGATCCCGATGTTATTTTAG
TCGGTGAAATTCGTGATGAAGAAACAGCGAAAATTGCTATAAGAGCAAGTTTGACTGGCCATTTAGTAATGACGACATTG
CATACGAATGATGCGAGAGGGGCGATACTTCGGTTCATGGATTTTGGCATAACGAGGCAAGAAATCGAACAATCTTTATT
AGCTATAGCTGCACAGCGACTTGTCGAATTAAAGTGTCCGTTTTGCAAAAGAAAGTGCTCAACTTTATGCAAATCAATGA
GGCAAGTAAGGCAAGCGAGTATTTATGAGTTGTTATATGGATATGAGTTAAAACAAGCGATTAAAGAAGCAAACGGGGAA
TGTGTCACATACAAGCACGAAACATTACAATCTTCGATACGAAAAGGATACGCTTTAGGGTTTTTAGAAGAAGATGTTTA
TGTTTAA

Upstream 100 bases:

>100_bases
TTTCACAAACATATTTTTCCTTTTCTCTCTAGTGAAAATACAAAAATGCCGATTTTTCTTATGAATTTTTTCATGCTATA
TACATAGTGGGGAGGGAAAA

Downstream 100 bases:

>100_bases
GGAAATATGGAGTTTAAGTGATCAAGTCATATTACTGAAACGATTAGGAGAACTATTAGAAAAAGGATACTCCCTTTTGC
AGGCATTAGAATTTTTACGG

Product: comG operon protein 1

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 348; Mature: 348

Protein sequence:

>348_residues
MMNGIESFANMILKEACRVQASDLHIVPRQKDVVVQLRIGKDLMTKYCIEKEFGEKLVSHFKFLASMDIGERRKPQNGSL
YLQMDGQEVYLRLSTLPTVYQESLVIRLHLQASIQPLSHLSLFPSTAKILLSFLRYSHGLLVFTGPTGSGKTTTMYALLE
VIRKKKTRRIVTLEDPVEKRNDDVLQIQINEKAGITYEAGLKAILRHDPDVILVGEIRDEETAKIAIRASLTGHLVMTTL
HTNDARGAILRFMDFGITRQEIEQSLLAIAAQRLVELKCPFCKRKCSTLCKSMRQVRQASIYELLYGYELKQAIKEANGE
CVTYKHETLQSSIRKGYALGFLEEDVYV

Sequences:

>Translated_348_residues
MMNGIESFANMILKEACRVQASDLHIVPRQKDVVVQLRIGKDLMTKYCIEKEFGEKLVSHFKFLASMDIGERRKPQNGSL
YLQMDGQEVYLRLSTLPTVYQESLVIRLHLQASIQPLSHLSLFPSTAKILLSFLRYSHGLLVFTGPTGSGKTTTMYALLE
VIRKKKTRRIVTLEDPVEKRNDDVLQIQINEKAGITYEAGLKAILRHDPDVILVGEIRDEETAKIAIRASLTGHLVMTTL
HTNDARGAILRFMDFGITRQEIEQSLLAIAAQRLVELKCPFCKRKCSTLCKSMRQVRQASIYELLYGYELKQAIKEANGE
CVTYKHETLQSSIRKGYALGFLEEDVYV
>Mature_348_residues
MMNGIESFANMILKEACRVQASDLHIVPRQKDVVVQLRIGKDLMTKYCIEKEFGEKLVSHFKFLASMDIGERRKPQNGSL
YLQMDGQEVYLRLSTLPTVYQESLVIRLHLQASIQPLSHLSLFPSTAKILLSFLRYSHGLLVFTGPTGSGKTTTMYALLE
VIRKKKTRRIVTLEDPVEKRNDDVLQIQINEKAGITYEAGLKAILRHDPDVILVGEIRDEETAKIAIRASLTGHLVMTTL
HTNDARGAILRFMDFGITRQEIEQSLLAIAAQRLVELKCPFCKRKCSTLCKSMRQVRQASIYELLYGYELKQAIKEANGE
CVTYKHETLQSSIRKGYALGFLEEDVYV

Specific function: Required for uptake of DNA by competent cells [H]

COG id: COG2804

COG function: function code NU; Type II secretory pathway, ATPase PulE/Tfp pilus assembly pathway, ATPase PilB

Gene ontology:

Cell location: Cell membrane; Peripheral membrane protein; Cytoplasmic side [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GSP E family [H]

Homologues:

Organism=Escherichia coli, GI1789723, Length=276, Percent_Identity=43.4782608695652, Blast_Score=231, Evalue=4e-62,
Organism=Escherichia coli, GI1786296, Length=275, Percent_Identity=40, Blast_Score=194, Evalue=7e-51,
Organism=Escherichia coli, GI87082188, Length=156, Percent_Identity=40.3846153846154, Blast_Score=107, Evalue=1e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR001482 [H]

Pfam domain/function: PF00437 GSPII_E [H]

EC number: NA

Molecular weight: Translated: 39530; Mature: 39530

Theoretical pI: Translated: 9.10; Mature: 9.10

Prosite motif: PS00662 T2SP_E

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMNGIESFANMILKEACRVQASDLHIVPRQKDVVVQLRIGKDLMTKYCIEKEFGEKLVSH
CCCHHHHHHHHHHHHHHCCCCCCEEEECCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHH
FKFLASMDIGERRKPQNGSLYLQMDGQEVYLRLSTLPTVYQESLVIRLHLQASIQPLSHL
HHHHHHCCCCCCCCCCCCEEEEEECCCEEEEEEECCCHHHHCCEEEEEEECCCCCHHHHH
SLFPSTAKILLSFLRYSHGLLVFTGPTGSGKTTTMYALLEVIRKKKTRRIVTLEDPVEKR
HCCCHHHHHHHHHHHHHCCEEEEECCCCCCCHHHHHHHHHHHHHHHHCEEEEECCCHHCC
NDDVLQIQINEKAGITYEAGLKAILRHDPDVILVGEIRDEETAKIAIRASLTGHLVMTTL
CCCEEEEEECCCCCCCHHHHHHHHHHCCCCEEEEECCCCCCCEEEEEEEECCCEEEEEEE
HTNDARGAILRFMDFGITRQEIEQSLLAIAAQRLVELKCPFCKRKCSTLCKSMRQVRQAS
ECCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHH
IYELLYGYELKQAIKEANGECVTYKHETLQSSIRKGYALGFLEEDVYV
HHHHHHHHHHHHHHHHCCCCEEEEHHHHHHHHHHCCCEEEEECCCCCC
>Mature Secondary Structure
MMNGIESFANMILKEACRVQASDLHIVPRQKDVVVQLRIGKDLMTKYCIEKEFGEKLVSH
CCCHHHHHHHHHHHHHHCCCCCCEEEECCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHH
FKFLASMDIGERRKPQNGSLYLQMDGQEVYLRLSTLPTVYQESLVIRLHLQASIQPLSHL
HHHHHHCCCCCCCCCCCCEEEEEECCCEEEEEEECCCHHHHCCEEEEEEECCCCCHHHHH
SLFPSTAKILLSFLRYSHGLLVFTGPTGSGKTTTMYALLEVIRKKKTRRIVTLEDPVEKR
HCCCHHHHHHHHHHHHHCCEEEEECCCCCCCHHHHHHHHHHHHHHHHCEEEEECCCHHCC
NDDVLQIQINEKAGITYEAGLKAILRHDPDVILVGEIRDEETAKIAIRASLTGHLVMTTL
CCCEEEEEECCCCCCCHHHHHHHHHHCCCCEEEEECCCCCCCEEEEEEEECCCEEEEEEE
HTNDARGAILRFMDFGITRQEIEQSLLAIAAQRLVELKCPFCKRKCSTLCKSMRQVRQAS
ECCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHH
IYELLYGYELKQAIKEANGECVTYKHETLQSSIRKGYALGFLEEDVYV
HHHHHHHHHHHHHHHHCCCCEEEEHHHHHHHHHHCCCEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 2507524; 8969508; 9384377; 9422590; 9723928 [H]