BacMap

Definition	Bacillus cereus AH820, complete genome.
Accession	NC_011773
Length	5,302,683

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The map label for this gene is fabG [H]

Identifier: 218904914

GI number: 218904914

Start: 3630776

End: 3631489

Strand: Reverse

Name: fabG [H]

Synonym: BCAH820_3798

Alternate gene names: 218904914

Gene position: 3631489-3630776 (Counterclockwise)

Preceding gene: 218904915

Following gene: 218904913

Centisome position: 68.48

GC content: 38.99

Gene sequence:

>714_bases
ATGAAAAAGTATGCATTAGTAACTGGAGGGAGCGGAGGGATTGGCTCTGCTATTTCGAAACAATTAATTCAAGATGGATA
TACAGTATATGTTCATTATAATAACAGTGAAGAGAAAGTGAATGAGTTGCAGAAAGAATGGGGTGAAGTGATTCCTGTTC
AAGCGAATTTAGCTTCTAGTGATGGAGCAGAGCAATTGTGGGAACAAATTGAACATCCTCTTGATGCTATCATATATGCA
GCTGGGAAGAGTATCTTTGGACTCGTAACAGATGTAACGAACGATGAATTGAATGATATGGTAGAACTTCAAGTGAAGAG
TATCTATAAATTATTATCGATGGCATTGCCATCTATGATTCAACGGAGAAGCGGTAATATTGTACTTGTTTCGTCTATAT
GGGGACAAATTGGCGCGTCATGTGAAGTGCTTTACTCGATGGTAAAAGGTGCGCAAAATTCATATGTGAAAGCTTTAGCG
AAAGAGGTTTCATTAAGTGGAATAAGAGTAAACGCGGTGGCGCCAGGTGCAATTGAAACGGAAATGTTAAACGTATTTTC
AGAAGAAGATAAGAATGAAATTGCGGAAGAGATTCCGTTAGGACGATTAGGATTACCGGAAGAAGTAGCAAAAACTGTGT
CATTTCTCGTATCWCCAGGTGCATCTTATATAACTGGACAAATTATCGGAGTAAATGGCGGGTGGCATTGCTAA

Upstream 100 bases:

>100_bases
GTTTTATAATAATACCCTCATCTTATCATTGATAAATTGTAAGATGAGGGTATTATTTATTTGTAGGGAAACGATTTTTT
TGAGATAAGAGAGGAATTGT

Downstream 100 bases:

>100_bases
AAATTTCTTACATAAAAAATGAAAAACTGTACAAATTAAGCATGATTCTATTACTAAGTAGTGAGGTGCTTACACATGTC
AGTTTTAGATAATTTTGATC

Product: 3-ketoacyl-(acyl-carrier-protein) reductase

Products: 3-oxoacyl-[acyl-carrier protein]; NADPH; H+

Alternate protein names: NA

Number of amino acids: Translated: 237; Mature: 237

Protein sequence:

>237_residues
MKKYALVTGGSGGIGSAISKQLIQDGYTVYVHYNNSEEKVNELQKEWGEVIPVQANLASSDGAEQLWEQIEHPLDAIIYA
AGKSIFGLVTDVTNDELNDMVELQVKSIYKLLSMALPSMIQRRSGNIVLVSSIWGQIGASCEVLYSMVKGAQNSYVKALA
KEVSLSGIRVNAVAPGAIETEMLNVFSEEDKNEIAEEIPLGRLGLPEEVAKTVSFLVSPGASYITGQIIGVNGGWHC

Sequences:

>Translated_237_residues
MKKYALVTGGSGGIGSAISKQLIQDGYTVYVHYNNSEEKVNELQKEWGEVIPVQANLASSDGAEQLWEQIEHPLDAIIYA
AGKSIFGLVTDVTNDELNDMVELQVKSIYKLLSMALPSMIQRRSGNIVLVSSIWGQIGASCEVLYSMVKGAQNSYVKALA
KEVSLSGIRVNAVAPGAIETEMLNVFSEEDKNEIAEEIPLGRLGLPEEVAKTVSFLVSPGASYITGQIIGVNGGWHC
>Mature_237_residues
MKKYALVTGGSGGIGSAISKQLIQDGYTVYVHYNNSEEKVNELQKEWGEVIPVQANLASSDGAEQLWEQIEHPLDAIIYA
AGKSIFGLVTDVTNDELNDMVELQVKSIYKLLSMALPSMIQRRSGNIVLVSSIWGQIGASCEVLYSMVKGAQNSYVKALA
KEVSLSGIRVNAVAPGAIETEMLNVFSEEDKNEIAEEIPLGRLGLPEEVAKTVSFLVSPGASYITGQIIGVNGGWHC

Specific function: Fatty acid biosynthesis pathway; first reduction step. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI40254992, Length=242, Percent_Identity=35.5371900826446, Blast_Score=114, Evalue=5e-26,
Organism=Homo sapiens, GI32483357, Length=241, Percent_Identity=33.6099585062241, Blast_Score=109, Evalue=2e-24,
Organism=Homo sapiens, GI15277342, Length=245, Percent_Identity=30.6122448979592, Blast_Score=101, Evalue=5e-22,
Organism=Homo sapiens, GI5031737, Length=240, Percent_Identity=34.1666666666667, Blast_Score=101, Evalue=7e-22,
Organism=Homo sapiens, GI66933014, Length=207, Percent_Identity=29.4685990338164, Blast_Score=91, Evalue=8e-19,
Organism=Homo sapiens, GI19923817, Length=248, Percent_Identity=28.6290322580645, Blast_Score=90, Evalue=2e-18,
Organism=Homo sapiens, GI7705925, Length=239, Percent_Identity=27.6150627615063, Blast_Score=79, Evalue=3e-15,
Organism=Homo sapiens, GI126723750, Length=248, Percent_Identity=28.6290322580645, Blast_Score=78, Evalue=9e-15,
Organism=Homo sapiens, GI59889578, Length=168, Percent_Identity=34.5238095238095, Blast_Score=77, Evalue=9e-15,
Organism=Homo sapiens, GI33667109, Length=190, Percent_Identity=32.6315789473684, Blast_Score=72, Evalue=4e-13,
Organism=Homo sapiens, GI10190704, Length=243, Percent_Identity=24.6913580246914, Blast_Score=68, Evalue=6e-12,
Organism=Homo sapiens, GI109715829, Length=241, Percent_Identity=26.5560165975104, Blast_Score=67, Evalue=1e-11,
Organism=Escherichia coli, GI1787335, Length=240, Percent_Identity=32.9166666666667, Blast_Score=131, Evalue=5e-32,
Organism=Escherichia coli, GI2367175, Length=244, Percent_Identity=34.4262295081967, Blast_Score=111, Evalue=4e-26,
Organism=Escherichia coli, GI87082100, Length=246, Percent_Identity=31.3008130081301, Blast_Score=108, Evalue=4e-25,
Organism=Escherichia coli, GI2367365, Length=234, Percent_Identity=27.3504273504274, Blast_Score=92, Evalue=3e-20,
Organism=Escherichia coli, GI1789378, Length=245, Percent_Identity=29.7959183673469, Blast_Score=91, Evalue=6e-20,
Organism=Escherichia coli, GI87082160, Length=242, Percent_Identity=26.8595041322314, Blast_Score=89, Evalue=2e-19,
Organism=Escherichia coli, GI1788459, Length=245, Percent_Identity=29.3877551020408, Blast_Score=89, Evalue=2e-19,
Organism=Escherichia coli, GI1790717, Length=240, Percent_Identity=23.75, Blast_Score=87, Evalue=1e-18,
Organism=Escherichia coli, GI1787905, Length=242, Percent_Identity=28.9256198347107, Blast_Score=84, Evalue=7e-18,
Organism=Escherichia coli, GI1786812, Length=242, Percent_Identity=28.9256198347107, Blast_Score=78, Evalue=4e-16,
Organism=Escherichia coli, GI1789208, Length=244, Percent_Identity=27.0491803278689, Blast_Score=77, Evalue=9e-16,
Organism=Escherichia coli, GI1786701, Length=221, Percent_Identity=24.8868778280543, Blast_Score=64, Evalue=9e-12,
Organism=Escherichia coli, GI1789057, Length=261, Percent_Identity=25.2873563218391, Blast_Score=63, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17560676, Length=252, Percent_Identity=35.3174603174603, Blast_Score=117, Evalue=5e-27,
Organism=Caenorhabditis elegans, GI17561402, Length=245, Percent_Identity=29.3877551020408, Blast_Score=99, Evalue=3e-21,
Organism=Caenorhabditis elegans, GI71994604, Length=250, Percent_Identity=31.2, Blast_Score=93, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI71994600, Length=250, Percent_Identity=29.2, Blast_Score=90, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI17555706, Length=247, Percent_Identity=29.5546558704453, Blast_Score=87, Evalue=7e-18,
Organism=Caenorhabditis elegans, GI25147288, Length=239, Percent_Identity=26.7782426778243, Blast_Score=87, Evalue=9e-18,
Organism=Caenorhabditis elegans, GI17562910, Length=258, Percent_Identity=31.0077519379845, Blast_Score=87, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI17562904, Length=256, Percent_Identity=30.078125, Blast_Score=84, Evalue=5e-17,
Organism=Caenorhabditis elegans, GI17508651, Length=245, Percent_Identity=28.1632653061224, Blast_Score=84, Evalue=6e-17,
Organism=Caenorhabditis elegans, GI17531453, Length=257, Percent_Identity=31.5175097276265, Blast_Score=82, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI17562906, Length=262, Percent_Identity=30.1526717557252, Blast_Score=80, Evalue=6e-16,
Organism=Caenorhabditis elegans, GI17536025, Length=248, Percent_Identity=28.6290322580645, Blast_Score=80, Evalue=8e-16,
Organism=Caenorhabditis elegans, GI17560332, Length=263, Percent_Identity=31.1787072243346, Blast_Score=80, Evalue=8e-16,
Organism=Caenorhabditis elegans, GI17562908, Length=264, Percent_Identity=30.3030303030303, Blast_Score=79, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI17536651, Length=248, Percent_Identity=27.8225806451613, Blast_Score=77, Evalue=7e-15,
Organism=Caenorhabditis elegans, GI17561272, Length=209, Percent_Identity=25.3588516746411, Blast_Score=76, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI193204405, Length=260, Percent_Identity=28.4615384615385, Blast_Score=76, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17551412, Length=259, Percent_Identity=29.3436293436293, Blast_Score=76, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI72000259, Length=254, Percent_Identity=27.1653543307087, Blast_Score=76, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17544670, Length=262, Percent_Identity=27.0992366412214, Blast_Score=75, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI115534694, Length=242, Percent_Identity=26.8595041322314, Blast_Score=75, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI17508895, Length=242, Percent_Identity=23.5537190082645, Blast_Score=73, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17563726, Length=254, Percent_Identity=29.5275590551181, Blast_Score=72, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17538480, Length=260, Percent_Identity=28.4615384615385, Blast_Score=70, Evalue=7e-13,
Organism=Caenorhabditis elegans, GI17538486, Length=264, Percent_Identity=29.1666666666667, Blast_Score=70, Evalue=8e-13,
Organism=Caenorhabditis elegans, GI17560220, Length=259, Percent_Identity=26.6409266409266, Blast_Score=69, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI17559104, Length=269, Percent_Identity=25.2788104089219, Blast_Score=68, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI17562990, Length=260, Percent_Identity=28.4615384615385, Blast_Score=65, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17560150, Length=260, Percent_Identity=28.0769230769231, Blast_Score=65, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI17538182, Length=248, Percent_Identity=25.8064516129032, Blast_Score=64, Evalue=7e-11,
Organism=Saccharomyces cerevisiae, GI6324126, Length=253, Percent_Identity=27.6679841897233, Blast_Score=81, Evalue=1e-16,
Organism=Saccharomyces cerevisiae, GI6323882, Length=233, Percent_Identity=27.0386266094421, Blast_Score=66, Evalue=5e-12,
Organism=Saccharomyces cerevisiae, GI6320089, Length=189, Percent_Identity=26.4550264550265, Blast_Score=64, Evalue=3e-11,
Organism=Drosophila melanogaster, GI21355319, Length=242, Percent_Identity=36.3636363636364, Blast_Score=116, Evalue=1e-26,
Organism=Drosophila melanogaster, GI24639444, Length=242, Percent_Identity=32.6446280991736, Blast_Score=114, Evalue=8e-26,
Organism=Drosophila melanogaster, GI28571526, Length=248, Percent_Identity=30.241935483871, Blast_Score=89, Evalue=3e-18,
Organism=Drosophila melanogaster, GI23397609, Length=243, Percent_Identity=27.9835390946502, Blast_Score=89, Evalue=4e-18,
Organism=Drosophila melanogaster, GI24644339, Length=252, Percent_Identity=28.1746031746032, Blast_Score=87, Evalue=1e-17,
Organism=Drosophila melanogaster, GI24643142, Length=235, Percent_Identity=28.0851063829787, Blast_Score=84, Evalue=7e-17,
Organism=Drosophila melanogaster, GI21357041, Length=253, Percent_Identity=29.2490118577075, Blast_Score=82, Evalue=2e-16,
Organism=Drosophila melanogaster, GI24644337, Length=178, Percent_Identity=33.7078651685393, Blast_Score=76, Evalue=2e-14,
Organism=Drosophila melanogaster, GI24640442, Length=194, Percent_Identity=27.8350515463918, Blast_Score=66, Evalue=2e-11,
Organism=Drosophila melanogaster, GI17737361, Length=252, Percent_Identity=25.7936507936508, Blast_Score=64, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: 1.1.1.100

Molecular weight: Translated: 25550; Mature: 25550

Theoretical pI: Translated: 4.46; Mature: 4.46

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKYALVTGGSGGIGSAISKQLIQDGYTVYVHYNNSEEKVNELQKEWGEVIPVQANLASS
CCCEEEEECCCCCHHHHHHHHHHHCCCEEEEEECCCHHHHHHHHHHHCCEEEEEECCCCC
DGAEQLWEQIEHPLDAIIYAAGKSIFGLVTDVTNDELNDMVELQVKSIYKLLSMALPSMI
CCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
QRRSGNIVLVSSIWGQIGASCEVLYSMVKGAQNSYVKALAKEVSLSGIRVNAVAPGAIET
HHCCCCEEEEECHHHHHCCHHHHHHHHHHCCHHHHHHHHHHHHHHCCEEEEEECCCHHHH
EMLNVFSEEDKNEIAEEIPLGRLGLPEEVAKTVSFLVSPGASYITGQIIGVNGGWHC
HHHHHHHHCHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCCCEEEEEEEECCCCCC
>Mature Secondary Structure
MKKYALVTGGSGGIGSAISKQLIQDGYTVYVHYNNSEEKVNELQKEWGEVIPVQANLASS
CCCEEEEECCCCCHHHHHHHHHHHCCCEEEEEECCCHHHHHHHHHHHCCEEEEEECCCCC
DGAEQLWEQIEHPLDAIIYAAGKSIFGLVTDVTNDELNDMVELQVKSIYKLLSMALPSMI
CCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
QRRSGNIVLVSSIWGQIGASCEVLYSMVKGAQNSYVKALAKEVSLSGIRVNAVAPGAIET
HHCCCCEEEEECHHHHHCCHHHHHHHHHHCCHHHHHHHHHHHHHHCCEEEEEECCCHHHH
EMLNVFSEEDKNEIAEEIPLGRLGLPEEVAKTVSFLVSPGASYITGQIIGVNGGWHC
HHHHHHHHCHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCCCEEEEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NADPH [C]

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: (3R)-3-hydroxyacyl-[acyl-carrier protein]; NADP+

Specific reaction: (3R)-3-hydroxyacyl-[acyl-carrier protein] + NADP+ = 3-oxoacyl-[acyl-carrier protein] + NADPH + H+

General reaction: Redox reaction [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]