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The map label for this gene is dppE [H]

Identifier: 218904712

GI number: 218904712

Start: 3433600

End: 3435312

Strand: Reverse

Name: dppE [H]

Synonym: BCAH820_3596

Alternate gene names: 218904712

Gene position: 3435312-3433600 (Counterclockwise)

Preceding gene: 218904713

Following gene: 218904711

Centisome position: 64.78

GC content: 35.96

Gene sequence:

>1713_bases
GTGAAAAAGAAAAAAATGAAAAAACTAACAGCAGTTGTAGCACCAGTTTTAGCAATGAGTATGGCATTAACAGCATGTTC
TACATCAGGTGGAGATAAGAAGACAAGCACAAATTCTAGCTCTGGCGGAGATAGCAAATCAGAAGAAAAATTAGCAGCGA
AACAAGTGCTAAATCGTACAGAAACAAATGAGATTCCAACAATGGATACTTCTAAAAATACTGATACATTAGGTTCTCAA
ATTTTAGGGAACACAATGGAAGGTTTATATCGATTAGATAAAGATAACAAACCAATCCCAGCTGCGGCAGAGTCAAGCAC
AAAGAGTGAGGATGGTAAAAAATATACATTCAAATTACGTAAAGATGCAAAATGGTCAAATGGTGATCCTGTAACAGCAA
AAGATTTCGTATTTGCATGGCAACGTTTATTAGACCCAAAAACAGCTGCTGAGTATGCATTTATCGCATTCCCAATTAAA
AATGCAGAAGCGGTTAATAAAGGTGAAAAACCTGTAGCTGAACTAGGGGTAAAAGCAGTAGATGATCTTACTTTAGAAGT
TGAATTAGATCAAGCGGTACCATACTTCTTAAACTTAGTAGCATTCCCATCATACTATCCGTTAAATGAGAAGTTCGTAA
AAGAAAAAGGAGATAAATACGGTTTAGAGTCTGATACGACAGTATATAACGGACCGTTCGTACTTACTGATTGGAAACAT
GAGCAAGGATGGAAATTGAAGAAAAACGATCAATATTGGGATAAAAAGACTGTAAAACTAGATGAAATCAACTATAGCGT
AGTAAAAGAAGTAGCTACAAGAGTAAACTTATATGATACAAATGCAATTGATTTTGCACTTCTATCAGGAGAATTTGTTG
ATAAGTATAGAAATAATAAAGAAGAGTTTGGCACATACTCACAAGTAAGTACTTATTTCTTACGTATGAACCAAAAACGT
GGCGGACAAGATACGCCATTAAAGAGCCAAAAATTACGTGAAGCAATTGCACTTTCAATCGATAAAAAGAATTTAGCAAA
CGTTATCTTAAATGATGGATCTAAACCTGCGGACTTCTTAGTACCGAAAGGATTAGCAACTGGACCAGACGGTAAAGACT
TCCAAGAAACATTTAAAAACGGTATTAAACCAGATGCGAAAAAAGCAGCAGCTGCATGGGATGAAGCGAAAAAAGAGCTT
GGAAAAGACCAAGTTACAATTGAGCTATTAAACTATGACACTGGTAATGCGAAAAAAGTTGGGGAATATGTAAAAGACCA
AATTGAGAAAAACTTAAAAGGTGTAACTGTTAATATTAAACTTCAACCATTCAAACAAAAGCTGAAATTAGAAACAGAGC
AAGATTATGATTTATCATATGCTGGTTGGGGACCTGACTACGCTGACCCAATGACATTCTTAGATATGTTCCAGTCTAAT
CATTCTCATAACCAAATGAGCTTCGCTGATCCGAAGTATGATGATATGATCAAAAAAGCTGGCGGAGAATTAATGGGTGA
TGCGAAGAAACGTTGGGAAGAGCTAGGAAAAGCTGAGAAATTACTTCTTGAGCAAGATGTAGCACTTGTACCTTTATACC
AACGTGGTGATGCATATGTTCAAAAACCAAATGCAAAAGGCATCGTTCACCATAACATTAGCCCAGAGTATAGCTTCAAG
TGGGCGTACATGACTGAAAAAGATGGAAAATAA

Upstream 100 bases:

>100_bases
ATAATAGTTAATAAGAATCTTCTGATAAATATATAAAGAAAAACAGAATTATCAGAAAATTCTTAAATGAGAGCGTTAAG
AATTAGGGAGGGTACAGAAA

Downstream 100 bases:

>100_bases
TTTTTAAGCAGTGAGGCTATATTTAAGTGGATGTATATAGGTTTCTTAGCTTATTTTGTAGTGAGTATCTCATCGTCCAC
AATAGAAAGATAAAATGATA

Product: oligopeptide transporter, periplasmic-binding protein

Products: ADP; phosphate; oligopeptides [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 570; Mature: 570

Protein sequence:

>570_residues
MKKKKMKKLTAVVAPVLAMSMALTACSTSGGDKKTSTNSSSGGDSKSEEKLAAKQVLNRTETNEIPTMDTSKNTDTLGSQ
ILGNTMEGLYRLDKDNKPIPAAAESSTKSEDGKKYTFKLRKDAKWSNGDPVTAKDFVFAWQRLLDPKTAAEYAFIAFPIK
NAEAVNKGEKPVAELGVKAVDDLTLEVELDQAVPYFLNLVAFPSYYPLNEKFVKEKGDKYGLESDTTVYNGPFVLTDWKH
EQGWKLKKNDQYWDKKTVKLDEINYSVVKEVATRVNLYDTNAIDFALLSGEFVDKYRNNKEEFGTYSQVSTYFLRMNQKR
GGQDTPLKSQKLREAIALSIDKKNLANVILNDGSKPADFLVPKGLATGPDGKDFQETFKNGIKPDAKKAAAAWDEAKKEL
GKDQVTIELLNYDTGNAKKVGEYVKDQIEKNLKGVTVNIKLQPFKQKLKLETEQDYDLSYAGWGPDYADPMTFLDMFQSN
HSHNQMSFADPKYDDMIKKAGGELMGDAKKRWEELGKAEKLLLEQDVALVPLYQRGDAYVQKPNAKGIVHHNISPEYSFK
WAYMTEKDGK

Sequences:

>Translated_570_residues
MKKKKMKKLTAVVAPVLAMSMALTACSTSGGDKKTSTNSSSGGDSKSEEKLAAKQVLNRTETNEIPTMDTSKNTDTLGSQ
ILGNTMEGLYRLDKDNKPIPAAAESSTKSEDGKKYTFKLRKDAKWSNGDPVTAKDFVFAWQRLLDPKTAAEYAFIAFPIK
NAEAVNKGEKPVAELGVKAVDDLTLEVELDQAVPYFLNLVAFPSYYPLNEKFVKEKGDKYGLESDTTVYNGPFVLTDWKH
EQGWKLKKNDQYWDKKTVKLDEINYSVVKEVATRVNLYDTNAIDFALLSGEFVDKYRNNKEEFGTYSQVSTYFLRMNQKR
GGQDTPLKSQKLREAIALSIDKKNLANVILNDGSKPADFLVPKGLATGPDGKDFQETFKNGIKPDAKKAAAAWDEAKKEL
GKDQVTIELLNYDTGNAKKVGEYVKDQIEKNLKGVTVNIKLQPFKQKLKLETEQDYDLSYAGWGPDYADPMTFLDMFQSN
HSHNQMSFADPKYDDMIKKAGGELMGDAKKRWEELGKAEKLLLEQDVALVPLYQRGDAYVQKPNAKGIVHHNISPEYSFK
WAYMTEKDGK
>Mature_570_residues
MKKKKMKKLTAVVAPVLAMSMALTACSTSGGDKKTSTNSSSGGDSKSEEKLAAKQVLNRTETNEIPTMDTSKNTDTLGSQ
ILGNTMEGLYRLDKDNKPIPAAAESSTKSEDGKKYTFKLRKDAKWSNGDPVTAKDFVFAWQRLLDPKTAAEYAFIAFPIK
NAEAVNKGEKPVAELGVKAVDDLTLEVELDQAVPYFLNLVAFPSYYPLNEKFVKEKGDKYGLESDTTVYNGPFVLTDWKH
EQGWKLKKNDQYWDKKTVKLDEINYSVVKEVATRVNLYDTNAIDFALLSGEFVDKYRNNKEEFGTYSQVSTYFLRMNQKR
GGQDTPLKSQKLREAIALSIDKKNLANVILNDGSKPADFLVPKGLATGPDGKDFQETFKNGIKPDAKKAAAAWDEAKKEL
GKDQVTIELLNYDTGNAKKVGEYVKDQIEKNLKGVTVNIKLQPFKQKLKLETEQDYDLSYAGWGPDYADPMTFLDMFQSN
HSHNQMSFADPKYDDMIKKAGGELMGDAKKRWEELGKAEKLLLEQDVALVPLYQRGDAYVQKPNAKGIVHHNISPEYSFK
WAYMTEKDGK

Specific function: Part of the binding-protein-dependent transport system for dipeptides; probably responsible for the binding of dipeptides with high affinity. Is expressed to facilitate adaptation to nutrient deficiency conditions, which also induce sporulation [H]

COG id: COG4166

COG function: function code E; ABC-type oligopeptide transport system, periplasmic component

Gene ontology:

Cell location: Cell membrane; Lipid-anchor (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial solute-binding protein 5 family [H]

Homologues:

Organism=Escherichia coli, GI1787495, Length=550, Percent_Identity=31.0909090909091, Blast_Score=224, Evalue=1e-59,
Organism=Escherichia coli, GI87081878, Length=535, Percent_Identity=29.5327102803738, Blast_Score=217, Evalue=2e-57,
Organism=Escherichia coli, GI1789397, Length=518, Percent_Identity=28.7644787644788, Blast_Score=203, Evalue=2e-53,
Organism=Escherichia coli, GI1787762, Length=460, Percent_Identity=25.2173913043478, Blast_Score=101, Evalue=1e-22,
Organism=Escherichia coli, GI1787052, Length=497, Percent_Identity=24.5472837022133, Blast_Score=90, Evalue=4e-19,
Organism=Escherichia coli, GI1789887, Length=515, Percent_Identity=24.4660194174757, Blast_Score=84, Evalue=2e-17,
Organism=Escherichia coli, GI1789966, Length=490, Percent_Identity=24.2857142857143, Blast_Score=66, Evalue=5e-12,

Paralogues:

None

Copy number: 760 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 380 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 500 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2360 Molecules/Cell In: Stationary-Phase,

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000914 [H]

Pfam domain/function: PF00496 SBP_bac_5 [H]

EC number: NA

Molecular weight: Translated: 63939; Mature: 63939

Theoretical pI: Translated: 8.77; Mature: 8.77

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKKKMKKLTAVVAPVLAMSMALTACSTSGGDKKTSTNSSSGGDSKSEEKLAAKQVLNRT
CCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHH
ETNEIPTMDTSKNTDTLGSQILGNTMEGLYRLDKDNKPIPAAAESSTKSEDGKKYTFKLR
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCEEEEEEE
KDAKWSNGDPVTAKDFVFAWQRLLDPKTAAEYAFIAFPIKNAEAVNKGEKPVAELGVKAV
CCCCCCCCCCCCHHHHHHHHHHHCCCCHHHCEEEEEEECCCCHHHCCCCCCHHHHCCHHH
DDLTLEVELDQAVPYFLNLVAFPSYYPLNEKFVKEKGDKYGLESDTTVYNGPFVLTDWKH
CCEEEEEEECHHHHHHHHHHHCCCCCCCCHHHHHHCCCCCCCCCCCEEECCCEEEECCCC
EQGWKLKKNDQYWDKKTVKLDEINYSVVKEVATRVNLYDTNAIDFALLSGEFVDKYRNNK
CCCCCCCCCCCCCCCCCEEEECCCHHHHHHHHHHCCEEECCCEEEEECCCHHHHHHCCCH
EEFGTYSQVSTYFLRMNQKRGGQDTPLKSQKLREAIALSIDKKNLANVILNDGSKPADFL
HHCCCHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCCHHHHHHHEECCCCCCCHHC
VPKGLATGPDGKDFQETFKNGIKPDAKKAAAAWDEAKKELGKDQVTIELLNYDTGNAKKV
CCCCCCCCCCCCHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCEEEEEEEECCCCCHHHH
GEYVKDQIEKNLKGVTVNIKLQPFKQKLKLETEQDYDLSYAGWGPDYADPMTFLDMFQSN
HHHHHHHHHCCCCEEEEEEEECCHHHHHCCCCCCCCCCEECCCCCCCCCHHHHHHHHHCC
HSHNQMSFADPKYDDMIKKAGGELMGDAKKRWEELGKAEKLLLEQDVALVPLYQRGDAYV
CCCCCCCCCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCEE
QKPNAKGIVHHNISPEYSFKWAYMTEKDGK
ECCCCCCEEECCCCCCCEEEEEEECCCCCC
>Mature Secondary Structure
MKKKKMKKLTAVVAPVLAMSMALTACSTSGGDKKTSTNSSSGGDSKSEEKLAAKQVLNRT
CCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHH
ETNEIPTMDTSKNTDTLGSQILGNTMEGLYRLDKDNKPIPAAAESSTKSEDGKKYTFKLR
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCEEEEEEE
KDAKWSNGDPVTAKDFVFAWQRLLDPKTAAEYAFIAFPIKNAEAVNKGEKPVAELGVKAV
CCCCCCCCCCCCHHHHHHHHHHHCCCCHHHCEEEEEEECCCCHHHCCCCCCHHHHCCHHH
DDLTLEVELDQAVPYFLNLVAFPSYYPLNEKFVKEKGDKYGLESDTTVYNGPFVLTDWKH
CCEEEEEEECHHHHHHHHHHHCCCCCCCCHHHHHHCCCCCCCCCCCEEECCCEEEECCCC
EQGWKLKKNDQYWDKKTVKLDEINYSVVKEVATRVNLYDTNAIDFALLSGEFVDKYRNNK
CCCCCCCCCCCCCCCCCEEEECCCHHHHHHHHHHCCEEECCCEEEEECCCHHHHHHCCCH
EEFGTYSQVSTYFLRMNQKRGGQDTPLKSQKLREAIALSIDKKNLANVILNDGSKPADFL
HHCCCHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCCHHHHHHHEECCCCCCCHHC
VPKGLATGPDGKDFQETFKNGIKPDAKKAAAAWDEAKKELGKDQVTIELLNYDTGNAKKV
CCCCCCCCCCCCHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCEEEEEEEECCCCCHHHH
GEYVKDQIEKNLKGVTVNIKLQPFKQKLKLETEQDYDLSYAGWGPDYADPMTFLDMFQSN
HHHHHHHHHCCCCEEEEEEEECCHHHHHCCCCCCCCCCEECCCCCCCCCHHHHHHHHHCC
HSHNQMSFADPKYDDMIKKAGGELMGDAKKRWEELGKAEKLLLEQDVALVPLYQRGDAYV
CCCCCCCCCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCEE
QKPNAKGIVHHNISPEYSFKWAYMTEKDGK
ECCCCCCEEECCCCCCCEEEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; oligopeptides [Periplasm]; H2O [C]

Specific reaction: ATP + oligopeptides [Periplasm] + H2O = ADP + phosphate + oligopeptides [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1766370; 9384377 [H]