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The map label for this gene is ntdA [H]

Identifier: 218904389

GI number: 218904389

Start: 3115950

End: 3117275

Strand: Reverse

Name: ntdA [H]

Synonym: BCAH820_3273

Alternate gene names: 218904389

Gene position: 3117275-3115950 (Counterclockwise)

Preceding gene: 218904393

Following gene: 218904388

Centisome position: 58.79

GC content: 29.86

Gene sequence:

>1326_bases
GTGAAAACTCTTACTACAATTTCTGGACATAGTAAAGACAATTTAGCTTTATTAAAGTGCCTACAGGGGGAAACAAAAGA
AAAAGAATTTGAAATTAGTAATATATTACCGAATCACAGGATGAAAGAGAAATTATTTAGGAAAAACAAATTGAAAATAG
ATATTGATATAGAAAAAGATATTTTCAATTATAGCAGAAAAAATATACAGAAAATAGAATTTATGCCAGTTAATCGGTTG
ATTTCTCAAGATGAGGTTGAAAAAATTATTGGAGCTTTAAAAGATGTTTTACCGACAGGTCAATTTACAAGTGGACCATT
TTCAAAAAAGCTAGAAGAAGTAATCGGAAGTTATTTAAATAAAAATTTTGTAATTGCAACAAGCAGTGGTACAGATGCCC
TTATGGTGTCATTGTTATCTATTGGTATTCAGCCGGGAGATGAAGTAATTATGCCAGCTAATAGTTTTGCTGCTACTGAA
AATGCTGTGTTAGCGGTCGGAGCAAAACCTATATTTGTAGATATAGATCAGAAGAGTTATTGTATTGATCCATCTAAAAT
AGAAGAAGCTATCACCCAAAAAACAAAATGCATTTTACCTGTCCATTTGTATGGTAAGCAGTGTGAAATGAAAAAAATTC
GTGAAATCGCGGATATATATCAATTAAGAGTTATTGAAGATGCATGTCAAGCTATTGGTTCTTCAAATCTTGGAGAATAT
GGAGATATTATTGTCCTTAGTTTTAATCCATATAAGAAATTTGGTGTATGTGGTAAGGCAGGTGCAATAGTTACTAATAA
TGAAAATCTTGCAATACGTTGCAATCAATATAGTTATCATGGATTTGAAATTGATAAAAAAAATAAAAAGGTATTAGACT
TTGGATTCAATTCTAAAATTGATAATTTGCAAGCAGCTATTGGTTTGGAAAGAATTAAGTATTTATCATACAACAATTTA
AAAAGAGCGTATTTAGCTCAACGATATATTCGTGAGTTAAAGGATTTAGAGGATAGAGAATTAATAAAGCTACCTATGAT
GACAGAAGATAATGTCTGGCACCTTTTTCCGATTAGAGTTGAAAAAGGAAGAAGAGACGAGTTGAAAAATAAATTGTACC
AATTGTATAACATTGAAACAGATATTTATTATCCGGTATTATCTCATAAACAAAATACTAAGTGGTTAAAGGAAAATGAT
TTGCAAAACAATATGTTCAATACAGAGCAAGTTCATAAAGAAATATTACATCTACCTTTACATCCAAATATGATGTTAGA
AGAGCAAAATTTCGTTTTGGAGGGATTATTCAATGTCAATAAGTAA

Upstream 100 bases:

>100_bases
ATAGAAAAACCCTCCGTAAAAAATATGTTGACATGTAATCGATAACATAAAATATAGTCTACTCATGATTTTCAAAATAA
TTTCTTAGAGGTGATTTAAC

Downstream 100 bases:

>100_bases
TGAAGTTTTGAAGTCTTTAAATTTTGAAAGACTACCACAGGTTAAAAACCCGAAATATGTAGTGTTCTGTGATTTTGATG
AAACTTATTATCCTCATAGC

Product: degT/dnrJ/eryC1/strS family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 441; Mature: 441

Protein sequence:

>441_residues
MKTLTTISGHSKDNLALLKCLQGETKEKEFEISNILPNHRMKEKLFRKNKLKIDIDIEKDIFNYSRKNIQKIEFMPVNRL
ISQDEVEKIIGALKDVLPTGQFTSGPFSKKLEEVIGSYLNKNFVIATSSGTDALMVSLLSIGIQPGDEVIMPANSFAATE
NAVLAVGAKPIFVDIDQKSYCIDPSKIEEAITQKTKCILPVHLYGKQCEMKKIREIADIYQLRVIEDACQAIGSSNLGEY
GDIIVLSFNPYKKFGVCGKAGAIVTNNENLAIRCNQYSYHGFEIDKKNKKVLDFGFNSKIDNLQAAIGLERIKYLSYNNL
KRAYLAQRYIRELKDLEDRELIKLPMMTEDNVWHLFPIRVEKGRRDELKNKLYQLYNIETDIYYPVLSHKQNTKWLKEND
LQNNMFNTEQVHKEILHLPLHPNMMLEEQNFVLEGLFNVNK

Sequences:

>Translated_441_residues
MKTLTTISGHSKDNLALLKCLQGETKEKEFEISNILPNHRMKEKLFRKNKLKIDIDIEKDIFNYSRKNIQKIEFMPVNRL
ISQDEVEKIIGALKDVLPTGQFTSGPFSKKLEEVIGSYLNKNFVIATSSGTDALMVSLLSIGIQPGDEVIMPANSFAATE
NAVLAVGAKPIFVDIDQKSYCIDPSKIEEAITQKTKCILPVHLYGKQCEMKKIREIADIYQLRVIEDACQAIGSSNLGEY
GDIIVLSFNPYKKFGVCGKAGAIVTNNENLAIRCNQYSYHGFEIDKKNKKVLDFGFNSKIDNLQAAIGLERIKYLSYNNL
KRAYLAQRYIRELKDLEDRELIKLPMMTEDNVWHLFPIRVEKGRRDELKNKLYQLYNIETDIYYPVLSHKQNTKWLKEND
LQNNMFNTEQVHKEILHLPLHPNMMLEEQNFVLEGLFNVNK
>Mature_441_residues
MKTLTTISGHSKDNLALLKCLQGETKEKEFEISNILPNHRMKEKLFRKNKLKIDIDIEKDIFNYSRKNIQKIEFMPVNRL
ISQDEVEKIIGALKDVLPTGQFTSGPFSKKLEEVIGSYLNKNFVIATSSGTDALMVSLLSIGIQPGDEVIMPANSFAATE
NAVLAVGAKPIFVDIDQKSYCIDPSKIEEAITQKTKCILPVHLYGKQCEMKKIREIADIYQLRVIEDACQAIGSSNLGEY
GDIIVLSFNPYKKFGVCGKAGAIVTNNENLAIRCNQYSYHGFEIDKKNKKVLDFGFNSKIDNLQAAIGLERIKYLSYNNL
KRAYLAQRYIRELKDLEDRELIKLPMMTEDNVWHLFPIRVEKGRRDELKNKLYQLYNIETDIYYPVLSHKQNTKWLKEND
LQNNMFNTEQVHKEILHLPLHPNMMLEEQNFVLEGLFNVNK

Specific function: Part of the ntdABC operon that biosynthesizes the NTD (3,3'-neotrehalosadiamine) antibiotic [H]

COG id: COG0399

COG function: function code M; Predicted pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the degT/dnrJ/eryC1 family [H]

Homologues:

Organism=Escherichia coli, GI145693159, Length=381, Percent_Identity=33.3333333333333, Blast_Score=184, Evalue=1e-47,
Organism=Escherichia coli, GI2367285, Length=362, Percent_Identity=29.5580110497238, Blast_Score=135, Evalue=4e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000653
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF01041 DegT_DnrJ_EryC1 [H]

EC number: NA

Molecular weight: Translated: 50681; Mature: 50681

Theoretical pI: Translated: 8.24; Mature: 8.24

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKTLTTISGHSKDNLALLKCLQGETKEKEFEISNILPNHRMKEKLFRKNKLKIDIDIEKD
CCCEEECCCCCCCCHHHHHHHCCCCCCCCEEHHHCCCCHHHHHHHHHCCCEEEEEEECHH
IFNYSRKNIQKIEFMPVNRLISQDEVEKIIGALKDVLPTGQFTSGPFSKKLEEVIGSYLN
HHHHHHHCCEEEEEEEHHHHCCHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHC
KNFVIATSSGTDALMVSLLSIGIQPGDEVIMPANSFAATENAVLAVGAKPIFVDIDQKSY
CCEEEEECCCCHHHHHHHHHHCCCCCCCEEECCCCCCCCCCCEEEECCCEEEEEECCCCC
CIDPSKIEEAITQKTKCILPVHLYGKQCEMKKIREIADIYQLRVIEDACQAIGSSNLGEY
CCCHHHHHHHHHHHCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
GDIIVLSFNPYKKFGVCGKAGAIVTNNENLAIRCNQYSYHGFEIDKKNKKVLDFGFNSKI
CCEEEEEECCCHHHCCCCCCCEEEECCCCEEEEECCEEECCEEECCCCCEEEEECCCCCH
DNLQAAIGLERIKYLSYNNLKRAYLAQRYIRELKDLEDRELIKLPMMTEDNVWHLFPIRV
HHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCCEEEEEEEEE
EKGRRDELKNKLYQLYNIETDIYYPVLSHKQNTKWLKENDLQNNMFNTEQVHKEILHLPL
CCCCHHHHHHHHHHHHCCCCCEEEHHHCCCCCCCCHHHCCCCCCCCCHHHHHHHHHCCCC
HPNMMLEEQNFVLEGLFNVNK
CCCEEEECCCHHHHHHHCCCC
>Mature Secondary Structure
MKTLTTISGHSKDNLALLKCLQGETKEKEFEISNILPNHRMKEKLFRKNKLKIDIDIEKD
CCCEEECCCCCCCCHHHHHHHCCCCCCCCEEHHHCCCCHHHHHHHHHCCCEEEEEEECHH
IFNYSRKNIQKIEFMPVNRLISQDEVEKIIGALKDVLPTGQFTSGPFSKKLEEVIGSYLN
HHHHHHHCCEEEEEEEHHHHCCHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHC
KNFVIATSSGTDALMVSLLSIGIQPGDEVIMPANSFAATENAVLAVGAKPIFVDIDQKSY
CCEEEEECCCCHHHHHHHHHHCCCCCCCEEECCCCCCCCCCCEEEECCCEEEEEECCCCC
CIDPSKIEEAITQKTKCILPVHLYGKQCEMKKIREIADIYQLRVIEDACQAIGSSNLGEY
CCCHHHHHHHHHHHCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
GDIIVLSFNPYKKFGVCGKAGAIVTNNENLAIRCNQYSYHGFEIDKKNKKVLDFGFNSKI
CCEEEEEECCCHHHCCCCCCCEEEECCCCEEEEECCEEECCEEECCCCCEEEEECCCCCH
DNLQAAIGLERIKYLSYNNLKRAYLAQRYIRELKDLEDRELIKLPMMTEDNVWHLFPIRV
HHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCCEEEEEEEEE
EKGRRDELKNKLYQLYNIETDIYYPVLSHKQNTKWLKENDLQNNMFNTEQVHKEILHLPL
CCCCHHHHHHHHHHHHCCCCCEEEHHHCCCCCCCCHHHCCCCCCCCCHHHHHHHHHCCCC
HPNMMLEEQNFVLEGLFNVNK
CCCEEEECCCHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9579061; 9384377 [H]