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The map label for this gene is glsA2 [H]

Identifier: 218904280

GI number: 218904280

Start: 3000051

End: 3001031

Strand: Reverse

Name: glsA2 [H]

Synonym: BCAH820_3164

Alternate gene names: 218904280

Gene position: 3001031-3000051 (Counterclockwise)

Preceding gene: 218904281

Following gene: 218904279

Centisome position: 56.59

GC content: 37.61

Gene sequence:

>981_bases
ATGATAAAGGATTCTAGCGTTCAAGTTGAGGGGCAAGAAAAAGTTTACTTAGATCAATGGGTAGCTCATTATCGAACGTA
TGCAGCTAAGGGACGAAGCGCCAGTTATATTCCAGCTCTGGGGGAAATAAATGTATCGCAGCTAGGTATTTGTATAGTAA
AGCCAGATGGAACAATGATAAAGGCAGGAGATTGGGAGGTACCTTTCACATTACAAAGTATATCAAAAGTAATTGGTTTT
ATAGCTGCTTGTTTAAGTCGCGGTATTTCTTATGTATTAGAACGAGTTGATGTAGAACCAACTGGAGATGCCTTCAATTC
GATTATTCGTTTAGAGATACATAAACCAGGAAAACCTTTTAATCCCATGATCAATGCTGGAGCGATTACGATAGCTTCAC
TTTTGCCAGGGACATCGGTGCAAGAAAAATTAGAATCTATATACGTATTAATTGAGAAAATGATAGAGAAGCGTCCCGCT
ATTAATGAAATAGTATTTCAATCAGAATGGGAAACGGCTCATCGTAACAGAGCTTTAGCATACTATTTAAAGGAGAATGG
TTTTCTAGAATCAGATGTGGAGGAGACACTAGAGGTTTACTTAAAACAATGTTCGATTGAAATAAATACAGAAGATATTG
CCTTAATCGGGCTTATACTAGCACATGATGGATATCACCCTATTCGCAAAGAACAAGTACTCCCTAAAGAAGTAGCTAGG
TTAACAAAAGCTTTAATGCTTACTTGTGGAATGTACAACGCTTCTGGAAAATTTGCTGCTTTCATTGGGTTACCAGCTAA
AAGTGGGGTATCCGGCGGAATTATGACACTTGTTCCCTCAAAGTCTAAGAAGGATGTACCGTTCCTAGCTGGATGTGGTA
TTGGTATTTACGGACCAGCCATTGATGAATATGGGAATAGTTTACCAGGAATTATGTTGTTAGAACATATTGCAAAAGAA
TGGGATTTAAGTATATTTTAA

Upstream 100 bases:

>100_bases
ATGTCTGAATATCTTTCTTAGTTCTAGTGCAAATAGTATCGATGGTAGTAAAGAAAAAATTATTCTATATAAAGTTAATA
GTACGGGGGAATATTGTGAA

Downstream 100 bases:

>100_bases
AAAGGAGCACAGATATTTTGGTGTTAGAGCGAGTCCAAAAGTGTTCAGACCATATATTGTGTCTGAACATTTTTGAGTTA
TAAAGTATCTTTCTAAAGTA

Product: glutaminase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 326; Mature: 326

Protein sequence:

>326_residues
MIKDSSVQVEGQEKVYLDQWVAHYRTYAAKGRSASYIPALGEINVSQLGICIVKPDGTMIKAGDWEVPFTLQSISKVIGF
IAACLSRGISYVLERVDVEPTGDAFNSIIRLEIHKPGKPFNPMINAGAITIASLLPGTSVQEKLESIYVLIEKMIEKRPA
INEIVFQSEWETAHRNRALAYYLKENGFLESDVEETLEVYLKQCSIEINTEDIALIGLILAHDGYHPIRKEQVLPKEVAR
LTKALMLTCGMYNASGKFAAFIGLPAKSGVSGGIMTLVPSKSKKDVPFLAGCGIGIYGPAIDEYGNSLPGIMLLEHIAKE
WDLSIF

Sequences:

>Translated_326_residues
MIKDSSVQVEGQEKVYLDQWVAHYRTYAAKGRSASYIPALGEINVSQLGICIVKPDGTMIKAGDWEVPFTLQSISKVIGF
IAACLSRGISYVLERVDVEPTGDAFNSIIRLEIHKPGKPFNPMINAGAITIASLLPGTSVQEKLESIYVLIEKMIEKRPA
INEIVFQSEWETAHRNRALAYYLKENGFLESDVEETLEVYLKQCSIEINTEDIALIGLILAHDGYHPIRKEQVLPKEVAR
LTKALMLTCGMYNASGKFAAFIGLPAKSGVSGGIMTLVPSKSKKDVPFLAGCGIGIYGPAIDEYGNSLPGIMLLEHIAKE
WDLSIF
>Mature_326_residues
MIKDSSVQVEGQEKVYLDQWVAHYRTYAAKGRSASYIPALGEINVSQLGICIVKPDGTMIKAGDWEVPFTLQSISKVIGF
IAACLSRGISYVLERVDVEPTGDAFNSIIRLEIHKPGKPFNPMINAGAITIASLLPGTSVQEKLESIYVLIEKMIEKRPA
INEIVFQSEWETAHRNRALAYYLKENGFLESDVEETLEVYLKQCSIEINTEDIALIGLILAHDGYHPIRKEQVLPKEVAR
LTKALMLTCGMYNASGKFAAFIGLPAKSGVSGGIMTLVPSKSKKDVPFLAGCGIGIYGPAIDEYGNSLPGIMLLEHIAKE
WDLSIF

Specific function: Unknown

COG id: COG2066

COG function: function code E; Glutaminase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glutaminase family [H]

Homologues:

Organism=Homo sapiens, GI156104878, Length=311, Percent_Identity=37.2990353697749, Blast_Score=185, Evalue=5e-47,
Organism=Homo sapiens, GI20336214, Length=297, Percent_Identity=34.6801346801347, Blast_Score=169, Evalue=2e-42,
Organism=Escherichia coli, GI1786693, Length=296, Percent_Identity=36.1486486486487, Blast_Score=188, Evalue=4e-49,
Organism=Escherichia coli, GI1787804, Length=314, Percent_Identity=34.0764331210191, Blast_Score=184, Evalue=5e-48,
Organism=Caenorhabditis elegans, GI17507019, Length=301, Percent_Identity=33.5548172757475, Blast_Score=174, Evalue=5e-44,
Organism=Caenorhabditis elegans, GI17532727, Length=299, Percent_Identity=32.7759197324415, Blast_Score=168, Evalue=4e-42,
Organism=Caenorhabditis elegans, GI193204073, Length=308, Percent_Identity=32.4675324675325, Blast_Score=160, Evalue=9e-40,
Organism=Caenorhabditis elegans, GI193204075, Length=310, Percent_Identity=32.9032258064516, Blast_Score=157, Evalue=5e-39,
Organism=Drosophila melanogaster, GI281363241, Length=301, Percent_Identity=35.2159468438538, Blast_Score=175, Evalue=3e-44,
Organism=Drosophila melanogaster, GI24653162, Length=301, Percent_Identity=35.2159468438538, Blast_Score=175, Evalue=3e-44,
Organism=Drosophila melanogaster, GI281363239, Length=304, Percent_Identity=34.8684210526316, Blast_Score=175, Evalue=3e-44,
Organism=Drosophila melanogaster, GI116008307, Length=304, Percent_Identity=34.8684210526316, Blast_Score=175, Evalue=4e-44,
Organism=Drosophila melanogaster, GI24653164, Length=304, Percent_Identity=34.8684210526316, Blast_Score=175, Evalue=4e-44,
Organism=Drosophila melanogaster, GI24653156, Length=304, Percent_Identity=34.8684210526316, Blast_Score=175, Evalue=4e-44,
Organism=Drosophila melanogaster, GI24653158, Length=304, Percent_Identity=34.8684210526316, Blast_Score=175, Evalue=4e-44,
Organism=Drosophila melanogaster, GI24653166, Length=304, Percent_Identity=34.8684210526316, Blast_Score=175, Evalue=5e-44,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012338
- InterPro:   IPR015868 [H]

Pfam domain/function: PF04960 Glutaminase [H]

EC number: =3.5.1.2 [H]

Molecular weight: Translated: 35825; Mature: 35825

Theoretical pI: Translated: 5.70; Mature: 5.70

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIKDSSVQVEGQEKVYLDQWVAHYRTYAAKGRSASYIPALGEINVSQLGICIVKPDGTMI
CCCCCCEEECCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHEEEEEECCCCCEE
KAGDWEVPFTLQSISKVIGFIAACLSRGISYVLERVDVEPTGDAFNSIIRLEIHKPGKPF
ECCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHCCEEEEEEECCCCCC
NPMINAGAITIASLLPGTSVQEKLESIYVLIEKMIEKRPAINEIVFQSEWETAHRNRALA
CCCCCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHCCCCHHHHHCCCEEE
YYLKENGFLESDVEETLEVYLKQCSIEINTEDIALIGLILAHDGYHPIRKEQVLPKEVAR
EEEECCCCCHHHHHHHHHHHHHHCCEEECCCHHHHHHHHHHCCCCCCHHHHCCCHHHHHH
LTKALMLTCGMYNASGKFAAFIGLPAKSGVSGGIMTLVPSKSKKDVPFLAGCGIGIYGPA
HHHHHHHHHCCCCCCCCEEEEEECCCCCCCCCCEEEEECCCCCCCCCEEEECCCCCCCCC
IDEYGNSLPGIMLLEHIAKEWDLSIF
HHHHCCCCCHHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MIKDSSVQVEGQEKVYLDQWVAHYRTYAAKGRSASYIPALGEINVSQLGICIVKPDGTMI
CCCCCCEEECCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHEEEEEECCCCCEE
KAGDWEVPFTLQSISKVIGFIAACLSRGISYVLERVDVEPTGDAFNSIIRLEIHKPGKPF
ECCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHCCEEEEEEECCCCCC
NPMINAGAITIASLLPGTSVQEKLESIYVLIEKMIEKRPAINEIVFQSEWETAHRNRALA
CCCCCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHCCCCHHHHHCCCEEE
YYLKENGFLESDVEETLEVYLKQCSIEINTEDIALIGLILAHDGYHPIRKEQVLPKEVAR
EEEECCCCCHHHHHHHHHHHHHHCCEEECCCHHHHHHHHHHCCCCCCHHHHCCCHHHHHH
LTKALMLTCGMYNASGKFAAFIGLPAKSGVSGGIMTLVPSKSKKDVPFLAGCGIGIYGPA
HHHHHHHHHCCCCCCCCEEEEEECCCCCCCCCCEEEEECCCCCCCCCEEEECCCCCCCCC
IDEYGNSLPGIMLLEHIAKEWDLSIF
HHHHCCCCCHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12721629 [H]