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The map label for this gene is glnK [H]

Identifier: 218904279

GI number: 218904279

Start: 2998501

End: 2999817

Strand: Reverse

Name: glnK [H]

Synonym: BCAH820_3163

Alternate gene names: 218904279

Gene position: 2999817-2998501 (Counterclockwise)

Preceding gene: 218904280

Following gene: 218904278

Centisome position: 56.57

GC content: 31.13

Gene sequence:

>1317_bases
GTGATTATTTTGAATCTTAGTAATTTAGTAAAAAAAGACATCTATATTCTCGTTTTAATGATACTTACAGTACCCTTAGT
AGGTGAAATAAAGTCATTTCCTTTAAATGAAACATTTAGAATGAGCTTTGGTGCACCAACATTTTTCTTTTTTTTGTTAT
TGTTTCGACGAATTCCAGCATTTTTACCGGGTTTTTTAACAGCAATAGTCGTTGTAGTATTTCGTATCTCAATGGATGTC
ATTATAAAGGGAAATATGGATTGGTTAGCCGCTTTTCATACTCACTATCCTAGTTTCTTCTTTTATTTTACGTATTCGTA
TCTCTTTCATTTAGCAAAAATTAAACGTTTTTATCATCAACCACTAATGATTGGTTTGATCGGTTGCATGATTGAAATAT
TGTCAGACTGTGTGGAATTAATGATTCAATATTTCGTATTAAAAACATCAATCACATCCGAGGCAATAAATGAGATCATT
GTTATCGCATGCTCCCATAGTTTTATAGTTCTAAGCTTTTTCAATATGATGAAATTGTATGAAGCGCAATCAAGGGAGAG
GCACATAAAGAAACAAAATGAACATATGCTTATGCTTATTTCTAATTTATATGAAGATGCTGTTCATTTAAAAAAAACAT
TACAAGATGCTGAGAATATAACAAAAAAATCCTATGATTTATATAAAACCTTAGATTCTTTTGAGAATAAACAGATAGAT
TTTCAGTTTCAGGATTTAAGGCAACAGGCATTACAAATTGCTGGTGAGGTCCATGATGTTAAAAAGGATAATCAACGTAT
TTTTGCGGGGCTTTCAAAACTAATTTCTGATGAAAGTTTTACAGATTATATGTCTGTACATGAACTGGTAAATATCATTA
TACGGGCGAATACGAAATATGCACAGTTACTAAAGAAAGACATCCAATTTGTGTATAAAATTGATGGTGTACATTCTCAT
TATCATATTTATACAATCTTATCTATTATAAATAATATCGTTACAAACGCTGTAGAAGCTATCCAAGGTATGGGAACCAT
CACAATTGACATTAATAAAGACCACCAATTTGTTGAATTTCAAATAGGCGATAATGGTCCCGGCATTTCTTCAAAATATA
AAGATTCAATTTTTGAGCCTGGTTTTACTTCTAAATATGATAATTTAGGCAATCCATCGACAGGCATCGGACTATCGTAT
GTTAAAGAAATGGTCGAACAACTTGAAGGTGATGTTACGCTTGAGGACAGAACCGAAGGAAAAGGATCAATTTTTAAAAT
TAGATTAGGGATTGATCATATAATTTCGAAAGGGTGA

Upstream 100 bases:

>100_bases
CTTTCGTTTATATCTTATTTATTAGTTTTTGAAAAAAATAGAGTAGGTGTTGTATTAATACAAATAGGTTTGTATACTGA
CTGTTAGGCGAAAGTGAGAA

Downstream 100 bases:

>100_bases
TTCTATGTATTTTTATATAGTAGATGATGAAAAAGCGGTTCGCTCAATGTTGGCTCAAATTATCGAGGATGAAGATCTTG
GAGAGGTTATAGGAGAAGCT

Product: sensor histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 438; Mature: 438

Protein sequence:

>438_residues
MIILNLSNLVKKDIYILVLMILTVPLVGEIKSFPLNETFRMSFGAPTFFFFLLLFRRIPAFLPGFLTAIVVVVFRISMDV
IIKGNMDWLAAFHTHYPSFFFYFTYSYLFHLAKIKRFYHQPLMIGLIGCMIEILSDCVELMIQYFVLKTSITSEAINEII
VIACSHSFIVLSFFNMMKLYEAQSRERHIKKQNEHMLMLISNLYEDAVHLKKTLQDAENITKKSYDLYKTLDSFENKQID
FQFQDLRQQALQIAGEVHDVKKDNQRIFAGLSKLISDESFTDYMSVHELVNIIIRANTKYAQLLKKDIQFVYKIDGVHSH
YHIYTILSIINNIVTNAVEAIQGMGTITIDINKDHQFVEFQIGDNGPGISSKYKDSIFEPGFTSKYDNLGNPSTGIGLSY
VKEMVEQLEGDVTLEDRTEGKGSIFKIRLGIDHIISKG

Sequences:

>Translated_438_residues
MIILNLSNLVKKDIYILVLMILTVPLVGEIKSFPLNETFRMSFGAPTFFFFLLLFRRIPAFLPGFLTAIVVVVFRISMDV
IIKGNMDWLAAFHTHYPSFFFYFTYSYLFHLAKIKRFYHQPLMIGLIGCMIEILSDCVELMIQYFVLKTSITSEAINEII
VIACSHSFIVLSFFNMMKLYEAQSRERHIKKQNEHMLMLISNLYEDAVHLKKTLQDAENITKKSYDLYKTLDSFENKQID
FQFQDLRQQALQIAGEVHDVKKDNQRIFAGLSKLISDESFTDYMSVHELVNIIIRANTKYAQLLKKDIQFVYKIDGVHSH
YHIYTILSIINNIVTNAVEAIQGMGTITIDINKDHQFVEFQIGDNGPGISSKYKDSIFEPGFTSKYDNLGNPSTGIGLSY
VKEMVEQLEGDVTLEDRTEGKGSIFKIRLGIDHIISKG
>Mature_438_residues
MIILNLSNLVKKDIYILVLMILTVPLVGEIKSFPLNETFRMSFGAPTFFFFLLLFRRIPAFLPGFLTAIVVVVFRISMDV
IIKGNMDWLAAFHTHYPSFFFYFTYSYLFHLAKIKRFYHQPLMIGLIGCMIEILSDCVELMIQYFVLKTSITSEAINEII
VIACSHSFIVLSFFNMMKLYEAQSRERHIKKQNEHMLMLISNLYEDAVHLKKTLQDAENITKKSYDLYKTLDSFENKQID
FQFQDLRQQALQIAGEVHDVKKDNQRIFAGLSKLISDESFTDYMSVHELVNIIIRANTKYAQLLKKDIQFVYKIDGVHSH
YHIYTILSIINNIVTNAVEAIQGMGTITIDINKDHQFVEFQIGDNGPGISSKYKDSIFEPGFTSKYDNLGNPSTGIGLSY
VKEMVEQLEGDVTLEDRTEGKGSIFKIRLGIDHIISKG

Specific function: Member of the two-component regulatory system glnK/glnL that positively regulates the expression of the glsA-glnT operon in response to glutamine. Probably activates glnL by phosphorylation [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1790436, Length=104, Percent_Identity=33.6538461538462, Blast_Score=62, Evalue=8e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR004358
- InterPro:   IPR005467 [H]

Pfam domain/function: PF02518 HATPase_c [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 50404; Mature: 50404

Theoretical pI: Translated: 6.93; Mature: 6.93

Prosite motif: PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIILNLSNLVKKDIYILVLMILTVPLVGEIKSFPLNETFRMSFGAPTFFFFLLLFRRIPA
CEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHEECCCCHHHHHHHHHHHHHHH
FLPGFLTAIVVVVFRISMDVIIKGNMDWLAAFHTHYPSFFFYFTYSYLFHLAKIKRFYHQ
HHHHHHHHHHHHHHHHHHHEEEECCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHC
PLMIGLIGCMIEILSDCVELMIQYFVLKTSITSEAINEIIVIACSHSFIVLSFFNMMKLY
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEECCHHHHHHHHHHHHHH
EAQSRERHIKKQNEHMLMLISNLYEDAVHLKKTLQDAENITKKSYDLYKTLDSFENKQID
HHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
FQFQDLRQQALQIAGEVHDVKKDNQRIFAGLSKLISDESFTDYMSVHELVNIIIRANTKY
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCHH
AQLLKKDIQFVYKIDGVHSHYHIYTILSIINNIVTNAVEAIQGMGTITIDINKDHQFVEF
HHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCEEEEE
QIGDNGPGISSKYKDSIFEPGFTSKYDNLGNPSTGIGLSYVKEMVEQLEGDVTLEDRTEG
EECCCCCCCCCHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCEEEECCCCC
KGSIFKIRLGIDHIISKG
CCCEEEEEECHHHHHCCC
>Mature Secondary Structure
MIILNLSNLVKKDIYILVLMILTVPLVGEIKSFPLNETFRMSFGAPTFFFFLLLFRRIPA
CEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHEECCCCHHHHHHHHHHHHHHH
FLPGFLTAIVVVVFRISMDVIIKGNMDWLAAFHTHYPSFFFYFTYSYLFHLAKIKRFYHQ
HHHHHHHHHHHHHHHHHHHEEEECCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHC
PLMIGLIGCMIEILSDCVELMIQYFVLKTSITSEAINEIIVIACSHSFIVLSFFNMMKLY
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEECCHHHHHHHHHHHHHH
EAQSRERHIKKQNEHMLMLISNLYEDAVHLKKTLQDAENITKKSYDLYKTLDSFENKQID
HHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
FQFQDLRQQALQIAGEVHDVKKDNQRIFAGLSKLISDESFTDYMSVHELVNIIIRANTKY
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCHH
AQLLKKDIQFVYKIDGVHSHYHIYTILSIINNIVTNAVEAIQGMGTITIDINKDHQFVEF
HHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCEEEEE
QIGDNGPGISSKYKDSIFEPGFTSKYDNLGNPSTGIGLSYVKEMVEQLEGDVTLEDRTEG
EECCCCCCCCCHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCEEEECCCCC
KGSIFKIRLGIDHIISKG
CCCEEEEEECHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9384377; 8011666 [H]