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The map label for this gene is adP2 [C]

Identifier: 218904143

GI number: 218904143

Start: 2867039

End: 2868205

Strand: Reverse

Name: adP2 [C]

Synonym: BCAH820_3027

Alternate gene names: 218904143

Gene position: 2868205-2867039 (Counterclockwise)

Preceding gene: 218904144

Following gene: 218904142

Centisome position: 54.09

GC content: 37.53

Gene sequence:

>1167_bases
ATGAAAAAACGTAATTCAATGAAGTTAGCGAGTTTGACAGTTTTATTAGCGGGTACTACTCTATTTACACCTGGTTTCAC
TGTGAAAGCAGAGTCTACTCAAAGTATTTCGAATTCGTCAAAAGTACATGATCAAAAGAATCGGAATGGATGGAAACAAG
TAATGCAGGAAACAATCAAAATTGGAGCACCAGGGGTATTAGCTAAGACATCTAATAAAGGGAAAATTAGTAGTTATACT
GCTGGTGTAGCAGATTTAAGTACAAAGAAACCGGTGAAATCGGATTATCGCTTTCGGATTGGTAGTGTGACGAAAACTTT
TACCGCCACGACTGTTCTTCAATTAGTAGGAGAAAATCGCGTACAACTGGACGATTCAATTGAAAAGTGGCTACCGGGTC
TCATTCAAGGAAATGGGTATGATGGTAATCAAATTACGATACGTCAACTTTTGAATCATACAAGTGGTATCGCTGAATAC
TTAAAGTCAAAAGATGCTGACATAATGAATTCGAAAAAAACGTATACAGCAGAAGAAATAGTGAAAATAGGTCTTTCTCT
ACCTCCAGATTTTTCGCCAGGTAAAGGCTGGTCGTATTCAAACACAGGATACGTAATACTAGGAATGCTTATTGAAAAAA
TAACTGGTAATAGTTATGCGGAAGAAATCGAAAAGCGAATTATTGAACCTTTGGACTTGCCAAATACGTTTTTACCAGGT
AATTCACCTGTCATCCCAGGAAAGAATCATGCTCGTGGATATGTGAAAATGGAAGAAACAGGCGAGTTGAAAGACATTAC
GTATTATAATCCGAGTTTAGCTAATGCAGCTGGAGACATGATTTCTAATGCGGATGATTTAAACAAGTTCTTTTCATCTT
TACTCGGTGGTAAGTTACTGAAGGAACGCGAGCTAAAAGAAATGCTTACTACAGTTCCTATAGAAGGAAAAGGGATTGGT
GATGGATATGGTCTTGGAATCTATGAGACAAAACTTCCAAATGGTGTCTCAGTATGGGGGCACGGAGGATCAATTCCTGG
GTTTATGACTTTTGCTGGTGGAGTAATTGGAGGCAAGCATACATTTGCTGTCAATGTTAACTCTTTAGGTCCAGTTGATA
TTCTTACACAGTTTGATAAAATGATGCAAGTTGAATTTAATAAATAG

Upstream 100 bases:

>100_bases
AGTATTTCGTAAGGAATGGATAAGAAAAAAGACAGTTTTATCATATAGGATGAAAGTATAGCTTGAATCAATACGATATG
AATAGGGGAGAGAGATCCTT

Downstream 100 bases:

>100_bases
ATGAAGAGAAAGCGAATGGGGTTCTGCAATAGTTGTAAATAAAAGAGATGCTTTTTAAATTTCACAAATAAGGACAGTAT
TAACATTCATGATATGGTAT

Product: alkaline D-peptidase

Products: NA

Alternate protein names: DD-carboxypeptidase; DD-peptidase [H]

Number of amino acids: Translated: 388; Mature: 388

Protein sequence:

>388_residues
MKKRNSMKLASLTVLLAGTTLFTPGFTVKAESTQSISNSSKVHDQKNRNGWKQVMQETIKIGAPGVLAKTSNKGKISSYT
AGVADLSTKKPVKSDYRFRIGSVTKTFTATTVLQLVGENRVQLDDSIEKWLPGLIQGNGYDGNQITIRQLLNHTSGIAEY
LKSKDADIMNSKKTYTAEEIVKIGLSLPPDFSPGKGWSYSNTGYVILGMLIEKITGNSYAEEIEKRIIEPLDLPNTFLPG
NSPVIPGKNHARGYVKMEETGELKDITYYNPSLANAAGDMISNADDLNKFFSSLLGGKLLKERELKEMLTTVPIEGKGIG
DGYGLGIYETKLPNGVSVWGHGGSIPGFMTFAGGVIGGKHTFAVNVNSLGPVDILTQFDKMMQVEFNK

Sequences:

>Translated_388_residues
MKKRNSMKLASLTVLLAGTTLFTPGFTVKAESTQSISNSSKVHDQKNRNGWKQVMQETIKIGAPGVLAKTSNKGKISSYT
AGVADLSTKKPVKSDYRFRIGSVTKTFTATTVLQLVGENRVQLDDSIEKWLPGLIQGNGYDGNQITIRQLLNHTSGIAEY
LKSKDADIMNSKKTYTAEEIVKIGLSLPPDFSPGKGWSYSNTGYVILGMLIEKITGNSYAEEIEKRIIEPLDLPNTFLPG
NSPVIPGKNHARGYVKMEETGELKDITYYNPSLANAAGDMISNADDLNKFFSSLLGGKLLKERELKEMLTTVPIEGKGIG
DGYGLGIYETKLPNGVSVWGHGGSIPGFMTFAGGVIGGKHTFAVNVNSLGPVDILTQFDKMMQVEFNK
>Mature_388_residues
MKKRNSMKLASLTVLLAGTTLFTPGFTVKAESTQSISNSSKVHDQKNRNGWKQVMQETIKIGAPGVLAKTSNKGKISSYT
AGVADLSTKKPVKSDYRFRIGSVTKTFTATTVLQLVGENRVQLDDSIEKWLPGLIQGNGYDGNQITIRQLLNHTSGIAEY
LKSKDADIMNSKKTYTAEEIVKIGLSLPPDFSPGKGWSYSNTGYVILGMLIEKITGNSYAEEIEKRIIEPLDLPNTFLPG
NSPVIPGKNHARGYVKMEETGELKDITYYNPSLANAAGDMISNADDLNKFFSSLLGGKLLKERELKEMLTTVPIEGKGIG
DGYGLGIYETKLPNGVSVWGHGGSIPGFMTFAGGVIGGKHTFAVNVNSLGPVDILTQFDKMMQVEFNK

Specific function: Catalyzes distinct carboxypeptidation and transpeptidation reactions during the last stages of wall peptidoglycan synthesis. Mistaking a beta-lactam antibiotic molecule for a normal substrate (i.e., a D-alanyl-D-alanine- terminated peptide), it becomes im

COG id: COG1680

COG function: function code V; Beta-lactamase class C and other penicillin binding proteins

Gene ontology:

Cell location: Secreted [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S12 family [H]

Homologues:

Organism=Escherichia coli, GI1790593, Length=298, Percent_Identity=25.1677852348993, Blast_Score=81, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI115533026, Length=401, Percent_Identity=26.1845386533666, Blast_Score=90, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI17550934, Length=309, Percent_Identity=26.8608414239482, Blast_Score=87, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI17565630, Length=293, Percent_Identity=26.962457337884, Blast_Score=78, Evalue=7e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012338
- InterPro:   IPR001466 [H]

Pfam domain/function: PF00144 Beta-lactamase [H]

EC number: =3.4.16.4 [H]

Molecular weight: Translated: 42158; Mature: 42158

Theoretical pI: Translated: 9.68; Mature: 9.68

Prosite motif: PS00012 PHOSPHOPANTETHEINE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKRNSMKLASLTVLLAGTTLFTPGFTVKAESTQSISNSSKVHDQKNRNGWKQVMQETIK
CCCCCCCHHHHHHHHEECCEEECCCEEEEECCHHHHCCCHHHHHHHCCHHHHHHHHHHHH
IGAPGVLAKTSNKGKISSYTAGVADLSTKKPVKSDYRFRIGSVTKTFTATTVLQLVGENR
CCCCCEEEECCCCCCCCHHHCCHHHCCCCCCCCCCCCEEECCHHHHHHHHHHHHHHCCCC
VQLDDSIEKWLPGLIQGNGYDGNQITIRQLLNHTSGIAEYLKSKDADIMNSKKTYTAEEI
EEECHHHHHHCCHHEECCCCCCCEEHHHHHHHHHHHHHHHHHCCCCHHHCCCCCCCHHHH
VKIGLSLPPDFSPGKGWSYSNTGYVILGMLIEKITGNSYAEEIEKRIIEPLDLPNTFLPG
HHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCCCCCCC
NSPVIPGKNHARGYVKMEETGELKDITYYNPSLANAAGDMISNADDLNKFFSSLLGGKLL
CCCCCCCCCCCCCEEEECCCCCCCEEEEECCHHHHHHHHHHCCHHHHHHHHHHHHCHHHH
KERELKEMLTTVPIEGKGIGDGYGLGIYETKLPNGVSVWGHGGSIPGFMTFAGGVIGGKH
HHHHHHHHHHHCCCCCCCCCCCCCCCEEEECCCCCCEEECCCCCCCHHHHHHCCCCCCCE
TFAVNVNSLGPVDILTQFDKMMQVEFNK
EEEEECCCCCCHHHHHHHHHHHHEECCC
>Mature Secondary Structure
MKKRNSMKLASLTVLLAGTTLFTPGFTVKAESTQSISNSSKVHDQKNRNGWKQVMQETIK
CCCCCCCHHHHHHHHEECCEEECCCEEEEECCHHHHCCCHHHHHHHCCHHHHHHHHHHHH
IGAPGVLAKTSNKGKISSYTAGVADLSTKKPVKSDYRFRIGSVTKTFTATTVLQLVGENR
CCCCCEEEECCCCCCCCHHHCCHHHCCCCCCCCCCCCEEECCHHHHHHHHHHHHHHCCCC
VQLDDSIEKWLPGLIQGNGYDGNQITIRQLLNHTSGIAEYLKSKDADIMNSKKTYTAEEI
EEECHHHHHHCCHHEECCCCCCCEEHHHHHHHHHHHHHHHHHCCCCHHHCCCCCCCHHHH
VKIGLSLPPDFSPGKGWSYSNTGYVILGMLIEKITGNSYAEEIEKRIIEPLDLPNTFLPG
HHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCCCCCCC
NSPVIPGKNHARGYVKMEETGELKDITYYNPSLANAAGDMISNADDLNKFFSSLLGGKLL
CCCCCCCCCCCCCEEEECCCCCCCEEEEECCHHHHHHHHHHCCHHHHHHHHHHHHCHHHH
KERELKEMLTTVPIEGKGIGDGYGLGIYETKLPNGVSVWGHGGSIPGFMTFAGGVIGGKH
HHHHHHHHHHHCCCCCCCCCCCCCCCEEEECCCCCCEEECCCCCCCHHHHHHCCCCCCCE
TFAVNVNSLGPVDILTQFDKMMQVEFNK
EEEEECCCCCCHHHHHHHHHHHHEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 3830154; 7925404; 3030739; 2175384; 2386365; 3997832; 7490745 [H]