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The map label for this gene is aroA [H]

Identifier: 218904073

GI number: 218904073

Start: 2793092

End: 2794168

Strand: Reverse

Name: aroA [H]

Synonym: BCAH820_2957

Alternate gene names: 218904073

Gene position: 2794168-2793092 (Counterclockwise)

Preceding gene: 218904074

Following gene: 218904072

Centisome position: 52.69

GC content: 37.88

Gene sequence:

>1077_bases
ATGGCAAATCATGAATTAGATCAATTACGTAAACAGGTAGATGAAATTAACTTACAACTATTACACCTTTTAAACAAACG
CGGTGAAATCGTTCAAAAAATTGGGGAACAAAAGCAAGTACAAGGTACAAAACGTTTTGATCCAGTACGTGAGCGTGAAG
TGCTTGATATGATTGCAGAGAATAACGAAGGACCATTCGAAACATCAACAGTTCAACATATTTTCAAAACAATCTTCAAA
GCTAGCTTAGAATTACAAGAAGATGATAACCGTAAAGCATTACTAGTATCACGTAAAAAGAAACAAGAAAACACAATCGT
TGATGTAAAAGGTGAATTGATTGGTAACGGCACACAAACGTTCATCATGGGACCTTGCGCGGTAGAAAGCTTAGAGCAAG
TTCGCCAAGTAGGGCAAGCGATGAAAGACCAAGGCTTAAAATTAATGCGCGGTGGTGCTTTCAAACCGAGAACATCTCCA
TACGATTTCCAAGGTTTAGGAGTAGAAGGGCTACAAATTTTACGTCAAGTAGCAGATGAGTTCGACTTAGCGATCATTAG
TGAGATTTTAAATCCAAACGATGTTGAAATGGCATTAGACTACGTTGATGTAATTCAAGTTGGTGCACGTAACATGCAAA
ACTTCGATTTACTACGAGCTGTAGGTAAAGTTAACAAGCCAGTATTATTAAAACGTGGATTAGCAGCAACAATTGATGAG
TTCATTAATGCAGCGGAATACATCATTGCACAAGGTAATGACCAAATTATTCTATGTGAGCGCGGTATTCGCACATACGA
AAGAGCAACACGTAACACATTAGACATTTCAGCAGTACCGATCTTAAAGAAAGAAACACATTTACCAGTTGTTGTTGACG
TAACGCATTCAACTGGACGTAGAGATTTATTATTACCAACAGCGAAAGCGGCTCTTGCAATTGGTGCAGATGCAGTAATG
GCTGAAGTACATCCAGACCCAGCAGTTGCATTATCAGATTCTGCACAACAAATGGATATTCCGGAATTCCATAGATTCAT
GGAAGAGTTAAAAGGTTTCAAAAATAAATTATCTTAA

Upstream 100 bases:

>100_bases
TATCGATTCCACTTTAAATTTGTATAATTGACCAGTTCAGAAAATAGAGAATTTTTCATTCTCTTACTATACTTTTAAAA
CATTAGAGGAGGATTTCCAA

Downstream 100 bases:

>100_bases
TTCCATATTATATATGCGCTGAAGAGGAAACAGTAGTGCTTATCTCACTGTTAAAGAGAGCTGATGGTAGGTGTGAATCA
GTACAAAGATAAGCATGAAT

Product: bifunctional 3-deoxy-7-phosphoheptulonate synthase/chorismate mutase

Products: NA

Alternate protein names: Phospho-2-dehydro-3-deoxyheptonate aldolase; 3-deoxy-D-arabino-heptulosonate 7-phosphate synthase; DAHP synthase; Phospho-2-keto-3-deoxyheptonate aldolase; Chorismate mutase [H]

Number of amino acids: Translated: 358; Mature: 357

Protein sequence:

>358_residues
MANHELDQLRKQVDEINLQLLHLLNKRGEIVQKIGEQKQVQGTKRFDPVREREVLDMIAENNEGPFETSTVQHIFKTIFK
ASLELQEDDNRKALLVSRKKKQENTIVDVKGELIGNGTQTFIMGPCAVESLEQVRQVGQAMKDQGLKLMRGGAFKPRTSP
YDFQGLGVEGLQILRQVADEFDLAIISEILNPNDVEMALDYVDVIQVGARNMQNFDLLRAVGKVNKPVLLKRGLAATIDE
FINAAEYIIAQGNDQIILCERGIRTYERATRNTLDISAVPILKKETHLPVVVDVTHSTGRRDLLLPTAKAALAIGADAVM
AEVHPDPAVALSDSAQQMDIPEFHRFMEELKGFKNKLS

Sequences:

>Translated_358_residues
MANHELDQLRKQVDEINLQLLHLLNKRGEIVQKIGEQKQVQGTKRFDPVREREVLDMIAENNEGPFETSTVQHIFKTIFK
ASLELQEDDNRKALLVSRKKKQENTIVDVKGELIGNGTQTFIMGPCAVESLEQVRQVGQAMKDQGLKLMRGGAFKPRTSP
YDFQGLGVEGLQILRQVADEFDLAIISEILNPNDVEMALDYVDVIQVGARNMQNFDLLRAVGKVNKPVLLKRGLAATIDE
FINAAEYIIAQGNDQIILCERGIRTYERATRNTLDISAVPILKKETHLPVVVDVTHSTGRRDLLLPTAKAALAIGADAVM
AEVHPDPAVALSDSAQQMDIPEFHRFMEELKGFKNKLS
>Mature_357_residues
ANHELDQLRKQVDEINLQLLHLLNKRGEIVQKIGEQKQVQGTKRFDPVREREVLDMIAENNEGPFETSTVQHIFKTIFKA
SLELQEDDNRKALLVSRKKKQENTIVDVKGELIGNGTQTFIMGPCAVESLEQVRQVGQAMKDQGLKLMRGGAFKPRTSPY
DFQGLGVEGLQILRQVADEFDLAIISEILNPNDVEMALDYVDVIQVGARNMQNFDLLRAVGKVNKPVLLKRGLAATIDEF
INAAEYIIAQGNDQIILCERGIRTYERATRNTLDISAVPILKKETHLPVVVDVTHSTGRRDLLLPTAKAALAIGADAVMA
EVHPDPAVALSDSAQQMDIPEFHRFMEELKGFKNKLS

Specific function: Synthesis Of Kdo 8-P Which Is Required For Lipid A Maturation And Cellular Growth. [C]

COG id: COG2876

COG function: function code E; 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 chorismate mutase domain [H]

Homologues:

Organism=Escherichia coli, GI1787466, Length=209, Percent_Identity=28.7081339712919, Blast_Score=90, Evalue=2e-19,

Paralogues:

None

Copy number: 200 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR002701
- InterPro:   IPR010954
- InterPro:   IPR020822
- InterPro:   IPR006218
- InterPro:   IPR006268 [H]

Pfam domain/function: PF01817 CM_2; PF00793 DAHP_synth_1 [H]

EC number: =2.5.1.54; =5.4.99.5 [H]

Molecular weight: Translated: 40027; Mature: 39895

Theoretical pI: Translated: 5.72; Mature: 5.72

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MANHELDQLRKQVDEINLQLLHLLNKRGEIVQKIGEQKQVQGTKRFDPVREREVLDMIAE
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHC
NNEGPFETSTVQHIFKTIFKASLELQEDDNRKALLVSRKKKQENTIVDVKGELIGNGTQT
CCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEHHHHCCCCEEEECCCEECCCCCE
FIMGPCAVESLEQVRQVGQAMKDQGLKLMRGGAFKPRTSPYDFQGLGVEGLQILRQVADE
EEECHHHHHHHHHHHHHHHHHHHCCCHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHH
FDLAIISEILNPNDVEMALDYVDVIQVGARNMQNFDLLRAVGKVNKPVLLKRGLAATIDE
HHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCHHHHCCHHHHHHH
FINAAEYIIAQGNDQIILCERGIRTYERATRNTLDISAVPILKKETHLPVVVDVTHSTGR
HHHHHHHEEECCCCEEEEECCCCHHHHHHHCCCCCEEECCCEECCCCCCEEEEECCCCCC
RDLLLPTAKAALAIGADAVMAEVHPDPAVALSDSAQQMDIPEFHRFMEELKGFKNKLS
CCEECCHHHHHHHHCCHHHHEECCCCCCEEECCCCHHCCCHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
ANHELDQLRKQVDEINLQLLHLLNKRGEIVQKIGEQKQVQGTKRFDPVREREVLDMIAE
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHC
NNEGPFETSTVQHIFKTIFKASLELQEDDNRKALLVSRKKKQENTIVDVKGELIGNGTQT
CCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEHHHHCCCCEEEECCCEECCCCCE
FIMGPCAVESLEQVRQVGQAMKDQGLKLMRGGAFKPRTSPYDFQGLGVEGLQILRQVADE
EEECHHHHHHHHHHHHHHHHHHHCCCHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHH
FDLAIISEILNPNDVEMALDYVDVIQVGARNMQNFDLLRAVGKVNKPVLLKRGLAATIDE
HHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCHHHHCCHHHHHHH
FINAAEYIIAQGNDQIILCERGIRTYERATRNTLDISAVPILKKETHLPVVVDVTHSTGR
HHHHHHHEEECCCCEEEEECCCCHHHHHHHCCCCCEEECCCEECCCCCCEEEEECCCCCC
RDLLLPTAKAALAIGADAVMAEVHPDPAVALSDSAQQMDIPEFHRFMEELKGFKNKLS
CCEECCHHHHHHHHCCHHHHEECCCCCCEEECCCCHHCCCHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7496534; 9387221; 9384377 [H]