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The map label for this gene is phoP [H]

Identifier: 218903983

GI number: 218903983

Start: 2719008

End: 2719655

Strand: Reverse

Name: phoP [H]

Synonym: BCAH820_2867

Alternate gene names: 218903983

Gene position: 2719655-2719008 (Counterclockwise)

Preceding gene: 218903985

Following gene: 218903982

Centisome position: 51.29

GC content: 32.56

Gene sequence:

>648_bases
ATGAAAGTATTAATCGCAGATGATGAACAAGATATGCTAAGGATTTTAAAAGCTTATTTTGAGAAAGAAGGCTTCGAAGT
TTTCTTAGCGAAAGATGGAGAAGAAGCACTTCAAATATTTTATGATGAAAAAATTGATTTAGCTATTTTAGATTGGATGA
TGCCGAAACATAGCGGTATTACTGTTTGTCAGGAAATAAAGAAAAACTCAAGCGTAAAAGTATTAATGCTCACGGCGAAA
AGTGAAAGCGAAGATGAATTAGCAGCTCTTCAAAGCGGGGCAGATGAGTACGTAAAAAAACCATTTCATCCAGGTGTACT
CATTACTCGAGCGAAAAAGCTAATACAGCACGATGATGTCATTCAAGTTCAAGATTTGAAAATTGATTTTACGAAAAATA
AAGTTTATAAAAATGACAAGGAATTAGATATTACAAAAACAGAGCTAGAATTAATAAAATGTTTTTTAAATCATAAAGGG
ATGATTTTAACTCGTAAAAAATTGTTAGATATCGTATGGGGATTTGACTATTTTGGAGAAGAGCGAACTGTTGATACACA
TGTAAGGAGATTACGAAAAAAAATTGGAGAAAATATTATAAAGACGCACCGCGGGCTAGGATATAGTTTGGAGGAACAGA
GTGAATAA

Upstream 100 bases:

>100_bases
TATACCCTTAACTGGTTCAAATATTTTTCTGTCACATACATGTAACAAAGAAGTTGTATGATACAATTGATTTTTGTTTA
AAAGCAATGGAGGATAATGT

Downstream 100 bases:

>100_bases
GCTTGGAAAAAAGCTATTTCTTAGTATATCTTTAACCGTTATTCTTATATTTACGATCTCTTTATTATTAATTAACTATC
TTTTACCGAAATATAATATT

Product: DNA-binding response regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 215; Mature: 215

Protein sequence:

>215_residues
MKVLIADDEQDMLRILKAYFEKEGFEVFLAKDGEEALQIFYDEKIDLAILDWMMPKHSGITVCQEIKKNSSVKVLMLTAK
SESEDELAALQSGADEYVKKPFHPGVLITRAKKLIQHDDVIQVQDLKIDFTKNKVYKNDKELDITKTELELIKCFLNHKG
MILTRKKLLDIVWGFDYFGEERTVDTHVRRLRKKIGENIIKTHRGLGYSLEEQSE

Sequences:

>Translated_215_residues
MKVLIADDEQDMLRILKAYFEKEGFEVFLAKDGEEALQIFYDEKIDLAILDWMMPKHSGITVCQEIKKNSSVKVLMLTAK
SESEDELAALQSGADEYVKKPFHPGVLITRAKKLIQHDDVIQVQDLKIDFTKNKVYKNDKELDITKTELELIKCFLNHKG
MILTRKKLLDIVWGFDYFGEERTVDTHVRRLRKKIGENIIKTHRGLGYSLEEQSE
>Mature_215_residues
MKVLIADDEQDMLRILKAYFEKEGFEVFLAKDGEEALQIFYDEKIDLAILDWMMPKHSGITVCQEIKKNSSVKVLMLTAK
SESEDELAALQSGADEYVKKPFHPGVLITRAKKLIQHDDVIQVQDLKIDFTKNKVYKNDKELDITKTELELIKCFLNHKG
MILTRKKLLDIVWGFDYFGEERTVDTHVRRLRKKIGENIIKTHRGLGYSLEEQSE

Specific function: Member of the two-component regulatory system phoP/phoR involved in the regulation of alkaline phosphatase genes phoA and phoB and of phosphodiesterase [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1786599, Length=220, Percent_Identity=34.5454545454545, Blast_Score=151, Evalue=4e-38,
Organism=Escherichia coli, GI1789809, Length=225, Percent_Identity=28.4444444444444, Blast_Score=128, Evalue=4e-31,
Organism=Escherichia coli, GI1786911, Length=219, Percent_Identity=31.0502283105023, Blast_Score=122, Evalue=2e-29,
Organism=Escherichia coli, GI1790860, Length=221, Percent_Identity=33.9366515837104, Blast_Score=119, Evalue=1e-28,
Organism=Escherichia coli, GI1786784, Length=222, Percent_Identity=31.981981981982, Blast_Score=116, Evalue=1e-27,
Organism=Escherichia coli, GI1788394, Length=222, Percent_Identity=30.1801801801802, Blast_Score=114, Evalue=4e-27,
Organism=Escherichia coli, GI87082012, Length=218, Percent_Identity=28.4403669724771, Blast_Score=111, Evalue=4e-26,
Organism=Escherichia coli, GI1787229, Length=221, Percent_Identity=26.6968325791855, Blast_Score=110, Evalue=1e-25,
Organism=Escherichia coli, GI1790863, Length=227, Percent_Identity=31.2775330396476, Blast_Score=106, Evalue=1e-24,
Organism=Escherichia coli, GI2367329, Length=225, Percent_Identity=30.6666666666667, Blast_Score=103, Evalue=7e-24,
Organism=Escherichia coli, GI1787375, Length=221, Percent_Identity=28.0542986425339, Blast_Score=100, Evalue=7e-23,
Organism=Escherichia coli, GI145693140, Length=228, Percent_Identity=26.7543859649123, Blast_Score=91, Evalue=5e-20,
Organism=Escherichia coli, GI1790552, Length=224, Percent_Identity=29.0178571428571, Blast_Score=91, Evalue=6e-20,
Organism=Escherichia coli, GI1789402, Length=219, Percent_Identity=26.4840182648402, Blast_Score=86, Evalue=2e-18,
Organism=Escherichia coli, GI1788550, Length=102, Percent_Identity=37.2549019607843, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI1788191, Length=120, Percent_Identity=34.1666666666667, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1790437, Length=101, Percent_Identity=35.6435643564356, Blast_Score=65, Evalue=5e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR016032
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 24978; Mature: 24978

Theoretical pI: Translated: 6.26; Mature: 6.26

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKVLIADDEQDMLRILKAYFEKEGFEVFLAKDGEEALQIFYDEKIDLAILDWMMPKHSGI
CEEEEECCHHHHHHHHHHHHCCCCCEEEEECCCHHHHHHHHCCCCCEEHHHHHCCCCCCH
TVCQEIKKNSSVKVLMLTAKSESEDELAALQSGADEYVKKPFHPGVLITRAKKLIQHDDV
HHHHHHHCCCCEEEEEEEECCCCHHHHHHHHCCHHHHHHCCCCCCHHHHHHHHHHCCCCC
IQVQDLKIDFTKNKVYKNDKELDITKTELELIKCFLNHKGMILTRKKLLDIVWGFDYFGE
EEEEEEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHCCCCEEEEHHHHHHHHHCHHHCCC
ERTVDTHVRRLRKKIGENIIKTHRGLGYSLEEQSE
CCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCC
>Mature Secondary Structure
MKVLIADDEQDMLRILKAYFEKEGFEVFLAKDGEEALQIFYDEKIDLAILDWMMPKHSGI
CEEEEECCHHHHHHHHHHHHCCCCCEEEEECCCHHHHHHHHCCCCCEEHHHHHCCCCCCH
TVCQEIKKNSSVKVLMLTAKSESEDELAALQSGADEYVKKPFHPGVLITRAKKLIQHDDV
HHHHHHHCCCCEEEEEEEECCCCHHHHHHHHCCHHHHHHCCCCCCHHHHHHHHHHCCCCC
IQVQDLKIDFTKNKVYKNDKELDITKTELELIKCFLNHKGMILTRKKLLDIVWGFDYFGE
EEEEEEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHCCCCEEEEHHHHHHHHHCHHHCCC
ERTVDTHVRRLRKKIGENIIKTHRGLGYSLEEQSE
CCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1454550; 3036763; 9387221; 9384377; 8045898; 3142862 [H]