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The map label for this gene is pcoS [H]

Identifier: 218903982

GI number: 218903982

Start: 2717639

End: 2719015

Strand: Reverse

Name: pcoS [H]

Synonym: BCAH820_2866

Alternate gene names: 218903982

Gene position: 2719015-2717639 (Counterclockwise)

Preceding gene: 218903983

Following gene: 218903981

Centisome position: 51.28

GC content: 29.85

Gene sequence:

>1377_bases
GTGAATAAGCTTGGAAAAAAGCTATTTCTTAGTATATCTTTAACCGTTATTCTTATATTTACGATCTCTTTATTATTAAT
TAACTATCTTTTACCGAAATATAATATTTACAAAACACGAGAAAGCTTAGAAGGTATTATAGCGCAAATTCAGTCCATAC
CGAGAGAACAATTGGATGAAGCAATTACGAGCATTGAAAATGAGGGGAATGTTACGATTGCGTATACATCCATAAAAGAC
TCAGAAGATCATATTAATGATGAGTTACGTATGCAACTTACAAAAAAGAGAGTTGCCCTTAATAAAATTTGGATTACAAA
AGAAGAAATAATGAAAGTAAAGAAATTCGGACATTCGAATAAAATATATGATCAAGAGAAAATCAAATCTAGTTTTTTTG
TGAAATACATGGCGAAGGATGATATGTTGATTTTAGTAGGAGTTTCTATCGCACATTCAAATGAAATAATAAAAACGTTA
AACTCATTTTATTTATTCATTTTAGTTATTACGATTTTTCTCATTATCGTACTTGTATGGATATTGTCAAAAACAATTAC
GACACCGCTGAAAGAATTAAGTGATGTCGCAGAAGATATTTCACGTTTACAGTTTAAAAAGACAAAAGTGAAAACGAATG
ATGAAATAGGAGACTTAGCTACTAGTATTAATATCATGAGTGAAAAACTACAGGAAGCGCATCAAGATTTAACAGATCGT
AATGAACATTTAAAACGATTTATGGGTGATGTGACCCATGAATTAAAAACTCCAATCGCGTTAGTGAAAGCATATTCTAT
GGGAATAAAAGATGGTCTAGATGATGGTACATACATAGATACAATCATTAAACAATCGGATCACATATCAAACTTAATTG
AAGAGTTATTACGATTTTCTAAACTAGAAAGAGATGTGTTACAAAAAGAAGAATTTTCTATTAAATCACTAGTCCAAAGT
ATATTAGATAAGCATAAGATTGAACTGGAGTCGAAAGAAATTAATTTGCAAGTGAACTATAATGTTGGCGATGCAATTGT
TTATGCAGATGTAAATAAAATGAGAATGGTGTTCCAAAATTTAATTTCTAATGCGATAAAATATACATCAAATCAAAATA
TAAAAATTACATTAGAAGATCGAAATGAGAGTGTATATTTTCAAATTCAAAATGGTATGAATGCTGAACATATGAAAGAT
ATCGATAAAATTTGGGAACCTTTTTACGTCTTAGAATCTTCTCGTAGTAAAGATCGTTCAGGTACAGGACTAGGCTTAGC
GATCGTGAAAAGTATTGTAGAAAGACATGGTTTTGACTATGGCGTAGTTACTATAGGGGGAGAAATACGATTTTATATTC
ATATGAAGAATGACTAA

Upstream 100 bases:

>100_bases
GAGCGAACTGTTGATACACATGTAAGGAGATTACGAAAAAAAATTGGAGAAAATATTATAAAGACGCACCGCGGGCTAGG
ATATAGTTTGGAGGAACAGA

Downstream 100 bases:

>100_bases
TTCAATACTAGTAGAGCATCGTCTATTAATAGGCGATGTTTTTTTATTGATATATGTAAGTAGTAATTCAAAATATATAA
CCTTGAAAGCCCGTTGGAAG

Product: putative sensor histidine kinase SrrB

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 458; Mature: 458

Protein sequence:

>458_residues
MNKLGKKLFLSISLTVILIFTISLLLINYLLPKYNIYKTRESLEGIIAQIQSIPREQLDEAITSIENEGNVTIAYTSIKD
SEDHINDELRMQLTKKRVALNKIWITKEEIMKVKKFGHSNKIYDQEKIKSSFFVKYMAKDDMLILVGVSIAHSNEIIKTL
NSFYLFILVITIFLIIVLVWILSKTITTPLKELSDVAEDISRLQFKKTKVKTNDEIGDLATSINIMSEKLQEAHQDLTDR
NEHLKRFMGDVTHELKTPIALVKAYSMGIKDGLDDGTYIDTIIKQSDHISNLIEELLRFSKLERDVLQKEEFSIKSLVQS
ILDKHKIELESKEINLQVNYNVGDAIVYADVNKMRMVFQNLISNAIKYTSNQNIKITLEDRNESVYFQIQNGMNAEHMKD
IDKIWEPFYVLESSRSKDRSGTGLGLAIVKSIVERHGFDYGVVTIGGEIRFYIHMKND

Sequences:

>Translated_458_residues
MNKLGKKLFLSISLTVILIFTISLLLINYLLPKYNIYKTRESLEGIIAQIQSIPREQLDEAITSIENEGNVTIAYTSIKD
SEDHINDELRMQLTKKRVALNKIWITKEEIMKVKKFGHSNKIYDQEKIKSSFFVKYMAKDDMLILVGVSIAHSNEIIKTL
NSFYLFILVITIFLIIVLVWILSKTITTPLKELSDVAEDISRLQFKKTKVKTNDEIGDLATSINIMSEKLQEAHQDLTDR
NEHLKRFMGDVTHELKTPIALVKAYSMGIKDGLDDGTYIDTIIKQSDHISNLIEELLRFSKLERDVLQKEEFSIKSLVQS
ILDKHKIELESKEINLQVNYNVGDAIVYADVNKMRMVFQNLISNAIKYTSNQNIKITLEDRNESVYFQIQNGMNAEHMKD
IDKIWEPFYVLESSRSKDRSGTGLGLAIVKSIVERHGFDYGVVTIGGEIRFYIHMKND
>Mature_458_residues
MNKLGKKLFLSISLTVILIFTISLLLINYLLPKYNIYKTRESLEGIIAQIQSIPREQLDEAITSIENEGNVTIAYTSIKD
SEDHINDELRMQLTKKRVALNKIWITKEEIMKVKKFGHSNKIYDQEKIKSSFFVKYMAKDDMLILVGVSIAHSNEIIKTL
NSFYLFILVITIFLIIVLVWILSKTITTPLKELSDVAEDISRLQFKKTKVKTNDEIGDLATSINIMSEKLQEAHQDLTDR
NEHLKRFMGDVTHELKTPIALVKAYSMGIKDGLDDGTYIDTIIKQSDHISNLIEELLRFSKLERDVLQKEEFSIKSLVQS
ILDKHKIELESKEINLQVNYNVGDAIVYADVNKMRMVFQNLISNAIKYTSNQNIKITLEDRNESVYFQIQNGMNAEHMKD
IDKIWEPFYVLESSRSKDRSGTGLGLAIVKSIVERHGFDYGVVTIGGEIRFYIHMKND

Specific function: Probable member of a two-component regulatory system pcoS/pcoR. May activate pcoR by phosphorylation [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1788393, Length=261, Percent_Identity=26.8199233716475, Blast_Score=103, Evalue=2e-23,
Organism=Escherichia coli, GI1790346, Length=193, Percent_Identity=24.3523316062176, Blast_Score=88, Evalue=1e-18,
Organism=Escherichia coli, GI1789149, Length=332, Percent_Identity=23.7951807228916, Blast_Score=87, Evalue=3e-18,
Organism=Escherichia coli, GI1788279, Length=281, Percent_Identity=28.1138790035587, Blast_Score=84, Evalue=2e-17,
Organism=Escherichia coli, GI1786783, Length=322, Percent_Identity=24.5341614906832, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI1790861, Length=352, Percent_Identity=23.2954545454545, Blast_Score=74, Evalue=3e-14,
Organism=Escherichia coli, GI145693157, Length=217, Percent_Identity=26.2672811059908, Blast_Score=71, Evalue=2e-13,
Organism=Escherichia coli, GI1786600, Length=218, Percent_Identity=25.2293577981651, Blast_Score=70, Evalue=3e-13,
Organism=Escherichia coli, GI87082128, Length=303, Percent_Identity=22.7722772277228, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1790436, Length=216, Percent_Identity=25, Blast_Score=67, Evalue=3e-12,
Organism=Escherichia coli, GI48994928, Length=224, Percent_Identity=23.6607142857143, Blast_Score=67, Evalue=3e-12,
Organism=Escherichia coli, GI1790551, Length=295, Percent_Identity=25.7627118644068, Blast_Score=66, Evalue=6e-12,
Organism=Escherichia coli, GI1788549, Length=254, Percent_Identity=22.4409448818898, Blast_Score=64, Evalue=2e-11,
Organism=Escherichia coli, GI1787894, Length=201, Percent_Identity=26.3681592039801, Blast_Score=62, Evalue=1e-10,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR004358
- InterPro:   IPR006290
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 52713; Mature: 52713

Theoretical pI: Translated: 6.93; Mature: 6.93

Prosite motif: PS50885 HAMP ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNKLGKKLFLSISLTVILIFTISLLLINYLLPKYNIYKTRESLEGIIAQIQSIPREQLDE
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCHHHHHH
AITSIENEGNVTIAYTSIKDSEDHINDELRMQLTKKRVALNKIWITKEEIMKVKKFGHSN
HHHHCCCCCCEEEEEEECCCCHHHCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCC
KIYDQEKIKSSFFVKYMAKDDMLILVGVSIAHSNEIIKTLNSFYLFILVITIFLIIVLVW
CCCCHHHHHHHHHHHEECCCCEEEEEEEEHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
ILSKTITTPLKELSDVAEDISRLQFKKTKVKTNDEIGDLATSINIMSEKLQEAHQDLTDR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCH
NEHLKRFMGDVTHELKTPIALVKAYSMGIKDGLDDGTYIDTIIKQSDHISNLIEELLRFS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCHHHHHHHHHHHHHH
KLERDVLQKEEFSIKSLVQSILDKHKIELESKEINLQVNYNVGDAIVYADVNKMRMVFQN
HHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCEEEEEEEECCCCEEEEECHHHHHHHHHH
LISNAIKYTSNQNIKITLEDRNESVYFQIQNGMNAEHMKDIDKIWEPFYVLESSRSKDRS
HHHHHHHHCCCCCEEEEEECCCCEEEEEECCCCCHHHHHHHHHHHCCCEEECCCCCCCCC
GTGLGLAIVKSIVERHGFDYGVVTIGGEIRFYIHMKND
CCCHHHHHHHHHHHHCCCCEEEEEECCEEEEEEEECCC
>Mature Secondary Structure
MNKLGKKLFLSISLTVILIFTISLLLINYLLPKYNIYKTRESLEGIIAQIQSIPREQLDE
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCHHHHHH
AITSIENEGNVTIAYTSIKDSEDHINDELRMQLTKKRVALNKIWITKEEIMKVKKFGHSN
HHHHCCCCCCEEEEEEECCCCHHHCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCC
KIYDQEKIKSSFFVKYMAKDDMLILVGVSIAHSNEIIKTLNSFYLFILVITIFLIIVLVW
CCCCHHHHHHHHHHHEECCCCEEEEEEEEHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
ILSKTITTPLKELSDVAEDISRLQFKKTKVKTNDEIGDLATSINIMSEKLQEAHQDLTDR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCH
NEHLKRFMGDVTHELKTPIALVKAYSMGIKDGLDDGTYIDTIIKQSDHISNLIEELLRFS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCHHHHHHHHHHHHHH
KLERDVLQKEEFSIKSLVQSILDKHKIELESKEINLQVNYNVGDAIVYADVNKMRMVFQN
HHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCEEEEEEEECCCCEEEEECHHHHHHHHHH
LISNAIKYTSNQNIKITLEDRNESVYFQIQNGMNAEHMKDIDKIWEPFYVLESSRSKDRS
HHHHHHHHCCCCCEEEEEECCCCEEEEEECCCCCHHHHHHHHHHHCCCEEECCCCCCCCC
GTGLGLAIVKSIVERHGFDYGVVTIGGEIRFYIHMKND
CCCHHHHHHHHHHHHCCCCEEEEEECCEEEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8594334 [H]