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The map label for this gene is pkn1 [H]

Identifier: 218903918

GI number: 218903918

Start: 2663034

End: 2663678

Strand: Reverse

Name: pkn1 [H]

Synonym: BCAH820_2802

Alternate gene names: 218903918

Gene position: 2663678-2663034 (Counterclockwise)

Preceding gene: 218903919

Following gene: 218903917

Centisome position: 50.23

GC content: 36.9

Gene sequence:

>645_bases
ATGGTGAAAATTCCAGCAGGAAAAGTAGAATTAAGAGATGATCGCATAAAAAAAGAATGGCAAGTTCAAATAAAACCATT
TCTTCTTGCAAAGTATGTTTTAACAGTGGAATTATTTTACTCAATTACAAATCGTGCACTAAATGGTAATGAAAATAGTA
ATAAACCTGTTGTAAATATCTCATGGAATGATGCCATTATGTTTTGTAATTTACTTTCAAAAAAAGCGGGGTTAAAAGAA
TATTATTCTGTTAGTAATGGTGGTCAAATCGTTAGTTGTAATTTAGATTCAAATGGTTACCGATTGCCATCTGAGGCAGA
GTGGCAATACGCATGTAAAGCAGGTACGCCAGGATATACATATGGAGAACTTCAGAAAATAGCATGGTATAATGAAAATT
CAAATGGACAAATTCGTGACGTAGGTAAAAAAGAGCCGAATGCATGGGGATTGTATGATATGTTAGGGAACGTTTGGGAA
TGGTGCTATGATTTGTATGATGAAAAGGTGTATGGATCATACCGGATTTTTCGAGGCGGTAGTTGGGCTGAAGCAGCTAG
AGGTTGTGGTGCGACTTGTCGTCGCCGTAGCCATCCTACATTTTATATAGATGACCTTGGGTTTAGGCTCGCTAGGTCCA
TTTAG

Upstream 100 bases:

>100_bases
AATTTTTAGAGAAGTACGATACCATAAATAGTTAGATTATAAAAAGAATGAACATGGGGGGATAGAATTGAATAGATTCA
TTGACCAGGTTTATTTTAAT

Downstream 100 bases:

>100_bases
AAGAATAATAAGACCTGGGAGTATGGGAAATACCTGTAATCCTAATGACAACATAGAAAAGATTTAAATTAAGGAGTGTT
TAAAGTGGCACGTGTTTTAT

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 214; Mature: 214

Protein sequence:

>214_residues
MVKIPAGKVELRDDRIKKEWQVQIKPFLLAKYVLTVELFYSITNRALNGNENSNKPVVNISWNDAIMFCNLLSKKAGLKE
YYSVSNGGQIVSCNLDSNGYRLPSEAEWQYACKAGTPGYTYGELQKIAWYNENSNGQIRDVGKKEPNAWGLYDMLGNVWE
WCYDLYDEKVYGSYRIFRGGSWAEAARGCGATCRRRSHPTFYIDDLGFRLARSI

Sequences:

>Translated_214_residues
MVKIPAGKVELRDDRIKKEWQVQIKPFLLAKYVLTVELFYSITNRALNGNENSNKPVVNISWNDAIMFCNLLSKKAGLKE
YYSVSNGGQIVSCNLDSNGYRLPSEAEWQYACKAGTPGYTYGELQKIAWYNENSNGQIRDVGKKEPNAWGLYDMLGNVWE
WCYDLYDEKVYGSYRIFRGGSWAEAARGCGATCRRRSHPTFYIDDLGFRLARSI
>Mature_214_residues
MVKIPAGKVELRDDRIKKEWQVQIKPFLLAKYVLTVELFYSITNRALNGNENSNKPVVNISWNDAIMFCNLLSKKAGLKE
YYSVSNGGQIVSCNLDSNGYRLPSEAEWQYACKAGTPGYTYGELQKIAWYNENSNGQIRDVGKKEPNAWGLYDMLGNVWE
WCYDLYDEKVYGSYRIFRGGSWAEAARGCGATCRRRSHPTFYIDDLGFRLARSI

Specific function: Together with the serine/threonine kinase pknD, may play a role in the specific interactions with host proteins during intracellular growth [H]

COG id: COG1262

COG function: function code S; Uncharacterized conserved protein

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 protein kinase domain [H]

Homologues:

Organism=Homo sapiens, GI194248087, Length=181, Percent_Identity=28.7292817679558, Blast_Score=67, Evalue=9e-12,
Organism=Homo sapiens, GI194248088, Length=186, Percent_Identity=29.5698924731183, Blast_Score=67, Evalue=9e-12,
Organism=Homo sapiens, GI226437577, Length=186, Percent_Identity=29.5698924731183, Blast_Score=66, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016187
- InterPro:   IPR011009
- InterPro:   IPR000719
- InterPro:   IPR017442
- InterPro:   IPR005532 [H]

Pfam domain/function: PF03781 DUF323; PF00069 Pkinase [H]

EC number: =2.7.11.1 [H]

Molecular weight: Translated: 24492; Mature: 24492

Theoretical pI: Translated: 8.71; Mature: 8.71

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.8 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
2.8 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVKIPAGKVELRDDRIKKEWQVQIKPFLLAKYVLTVELFYSITNRALNGNENSNKPVVNI
CCCCCCCCEEECHHHCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEE
SWNDAIMFCNLLSKKAGLKEYYSVSNGGQIVSCNLDSNGYRLPSEAEWQYACKAGTPGYT
ECCCHHHHHHHHHHHCCHHHHHCCCCCCEEEEEEECCCCCCCCCCCCEEEEECCCCCCCC
YGELQKIAWYNENSNGQIRDVGKKEPNAWGLYDMLGNVWEWCYDLYDEKVYGSYRIFRGG
HHHEEEEEEECCCCCCEEEECCCCCCCCCCHHHHHHHHHHHHHHHHCCHHCCCEEEEECC
SWAEAARGCGATCRRRSHPTFYIDDLGFRLARSI
CHHHHHHCCCHHHHCCCCCCEEEECHHHHHHHCC
>Mature Secondary Structure
MVKIPAGKVELRDDRIKKEWQVQIKPFLLAKYVLTVELFYSITNRALNGNENSNKPVVNI
CCCCCCCCEEECHHHCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEE
SWNDAIMFCNLLSKKAGLKEYYSVSNGGQIVSCNLDSNGYRLPSEAEWQYACKAGTPGYT
ECCCHHHHHHHHHHHCCHHHHHCCCCCCEEEEEEECCCCCCCCCCCCEEEEECCCCCCCC
YGELQKIAWYNENSNGQIRDVGKKEPNAWGLYDMLGNVWEWCYDLYDEKVYGSYRIFRGG
HHHEEEEEEECCCCCCEEEECCCCCCCCCCHHHHHHHHHHHHHHHHCCHHCCCEEEEECC
SWAEAARGCGATCRRRSHPTFYIDDLGFRLARSI
CHHHHHHCCCHHHHCCCCCCEEEECHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10192388; 10684935; 10871362 [H]