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The map label for this gene is acoR [H]

Identifier: 218903884

GI number: 218903884

Start: 2637068

End: 2638918

Strand: Reverse

Name: acoR [H]

Synonym: BCAH820_2768

Alternate gene names: 218903884

Gene position: 2638918-2637068 (Counterclockwise)

Preceding gene: 218903885

Following gene: 218903883

Centisome position: 49.77

GC content: 34.58

Gene sequence:

>1851_bases
ATGTTAGCTTCACCGTTTTACTTACATACATGGAAAAAGTTTGTTGATGAAGGAGTCCTTGATTCGAACCGTATAAACGA
AAGAATTTCAGAGTCATGGTATCGATGTAAACAAGCAAATGTGAATCCTCATATGAATAAAGGTCAGAAAATTTTGTCTT
CTAATATTTTTCAAGACCAAAAGAAAAAGAGTGAAATCTTCTTAGATATAGCAATACCTCAAATACAAAATATGAGAAAA
ACCATTGATGAATTGCAAATGATGGCATTATTAATTGATCCAGATGGTTACGTTCTATCGTTAAGTGGAAATGAACAAAC
ATTGAAACGAGCAAAACATATTAACTTCATTGAAGGTGTGAAATGGACGGAAGCAGCTGTTGGTACAAATGCAATAGGAA
CAGCGCTTGAGATTGAAGAGGCTATTATGATAAGTGGTACAGAGCATTATTCTGTCGCATCTCATAGCTGGAGCTGTGCG
GCTGCTCCCATTCATAACGATGATGGGAAATTAATTGGTGTTCTAGATTTCTCCTGTCCAATTGAATTTTCGCATCCATA
TATGCTCGGAATGGTAACTTCGATTGCACATGCGATTGAACGTGAATGTAGTATTCGAGTACATCAAAATGAACTGCATT
TAATCCATCGTTTTTTAGATGTAATTGACAGTAATGAACAAGTTGTAATTTGTAATCATCGTAATGTTATCGTTTCTGCA
AGCAAGAGGATTCGGGAACGAGTAACTAATTGGTCACGAATGAAACTTGAAGATTTAATGTACTATGGATTGAAAACTAA
ATTAGAAGTTCCAGTATACAGTAATAATAGAATGATTGGGAAATGTATTTATGTAAAGGAAAATAAACAAGAAAAAGTAT
TTTCAACTTCCCTATTTATAAATGGCATCACTTTCCCTGGAGTAATTGGGACAAGCGATGCATTTCAACATACATTAGAA
GAAATTAAGCTTGTATCACCAACTGATGCAAGTGTATATGTTTGTGGTGAAACAGGTGTAGGAAAAGAATATGTAGCGAG
AGCGATTCATGAAAATAGTCCAAGAAAAAATGGTCCTTTTATAGCTGTTAACTGCGGTGCATTACCGAAAGAATTAATGG
AAAGTGAATTGTTTGGTTATGCTGAAGGAGCGTTTACAGGTGCACGGCGTCAAGGATATAAAGGGAAATTCGAACAAGCA
GACGGAGGAACAATATTTTTAGATGAAATTGGTGAAGTGCCTCCAGAGATGCAAGTAGCATTATTACGTGTTTTACAAGA
AAGAACAGTAACCCCAATTGGCAGTTCAAAAGAGGTGCCAGTTAATATTCGTATTATTACTGCGACACATAAAGATCTAT
TGCGATTAGTAGAAGAAGGGAAATTCCGTCAAGATTTATATTATCGTTTACATGTTTATCCGCTATATGTTCCATCGTTA
ATAGAAAGAAAAGAGGATATTCCGTACTTCATAAAACACTTTTGCAAACGAAAGAATTGGAATGTTGTATTTCCAAAAAG
TATTTGTAATCAATTTTCTCAGCATACATGGCCCGGAAATATTCGAGAATTATTAAATGCATTAGAACGCATCTACATTT
TGTCGCAAGGACGGGAAATATGCGAAAAACAAATCTCTTTTTTATTACAAACAATGATGAGAAATCAACATCAGCTTGAA
TTGCAAACAGAAAATAAAACAGAGAACACATTGAATTTCCGTGAAAAAATACAGCGTGATAGCATGATTGAAGCGCTAGA
AAAGACGAACGGAAATGTTTCGTTAGCTGCAAAACTGTTAGATGTACCTCGAAGTACATTTTATAAACGAATGCAAAAAT
ATAAGTTATAA

Upstream 100 bases:

>100_bases
GTGTCGTCTTTCTAGTTTTATTGAAAACGCTTTTATTCAGTTTTATAATAAAGGTATGTTTTTTACAGATCTCCAAAACA
ATAAATAGGGAGATGATACA

Downstream 100 bases:

>100_bases
AGTAGATTTTTGTAATCTACTTTTTCTTTGTGAGCTCATGTTCTGTCGGAATGTGCGCTTACCGGGGAAATAATAGAATA
GTTAGAAATTAATTTCCGGA

Product: putative acetoin operon transcriptional activator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 616; Mature: 616

Protein sequence:

>616_residues
MLASPFYLHTWKKFVDEGVLDSNRINERISESWYRCKQANVNPHMNKGQKILSSNIFQDQKKKSEIFLDIAIPQIQNMRK
TIDELQMMALLIDPDGYVLSLSGNEQTLKRAKHINFIEGVKWTEAAVGTNAIGTALEIEEAIMISGTEHYSVASHSWSCA
AAPIHNDDGKLIGVLDFSCPIEFSHPYMLGMVTSIAHAIERECSIRVHQNELHLIHRFLDVIDSNEQVVICNHRNVIVSA
SKRIRERVTNWSRMKLEDLMYYGLKTKLEVPVYSNNRMIGKCIYVKENKQEKVFSTSLFINGITFPGVIGTSDAFQHTLE
EIKLVSPTDASVYVCGETGVGKEYVARAIHENSPRKNGPFIAVNCGALPKELMESELFGYAEGAFTGARRQGYKGKFEQA
DGGTIFLDEIGEVPPEMQVALLRVLQERTVTPIGSSKEVPVNIRIITATHKDLLRLVEEGKFRQDLYYRLHVYPLYVPSL
IERKEDIPYFIKHFCKRKNWNVVFPKSICNQFSQHTWPGNIRELLNALERIYILSQGREICEKQISFLLQTMMRNQHQLE
LQTENKTENTLNFREKIQRDSMIEALEKTNGNVSLAAKLLDVPRSTFYKRMQKYKL

Sequences:

>Translated_616_residues
MLASPFYLHTWKKFVDEGVLDSNRINERISESWYRCKQANVNPHMNKGQKILSSNIFQDQKKKSEIFLDIAIPQIQNMRK
TIDELQMMALLIDPDGYVLSLSGNEQTLKRAKHINFIEGVKWTEAAVGTNAIGTALEIEEAIMISGTEHYSVASHSWSCA
AAPIHNDDGKLIGVLDFSCPIEFSHPYMLGMVTSIAHAIERECSIRVHQNELHLIHRFLDVIDSNEQVVICNHRNVIVSA
SKRIRERVTNWSRMKLEDLMYYGLKTKLEVPVYSNNRMIGKCIYVKENKQEKVFSTSLFINGITFPGVIGTSDAFQHTLE
EIKLVSPTDASVYVCGETGVGKEYVARAIHENSPRKNGPFIAVNCGALPKELMESELFGYAEGAFTGARRQGYKGKFEQA
DGGTIFLDEIGEVPPEMQVALLRVLQERTVTPIGSSKEVPVNIRIITATHKDLLRLVEEGKFRQDLYYRLHVYPLYVPSL
IERKEDIPYFIKHFCKRKNWNVVFPKSICNQFSQHTWPGNIRELLNALERIYILSQGREICEKQISFLLQTMMRNQHQLE
LQTENKTENTLNFREKIQRDSMIEALEKTNGNVSLAAKLLDVPRSTFYKRMQKYKL
>Mature_616_residues
MLASPFYLHTWKKFVDEGVLDSNRINERISESWYRCKQANVNPHMNKGQKILSSNIFQDQKKKSEIFLDIAIPQIQNMRK
TIDELQMMALLIDPDGYVLSLSGNEQTLKRAKHINFIEGVKWTEAAVGTNAIGTALEIEEAIMISGTEHYSVASHSWSCA
AAPIHNDDGKLIGVLDFSCPIEFSHPYMLGMVTSIAHAIERECSIRVHQNELHLIHRFLDVIDSNEQVVICNHRNVIVSA
SKRIRERVTNWSRMKLEDLMYYGLKTKLEVPVYSNNRMIGKCIYVKENKQEKVFSTSLFINGITFPGVIGTSDAFQHTLE
EIKLVSPTDASVYVCGETGVGKEYVARAIHENSPRKNGPFIAVNCGALPKELMESELFGYAEGAFTGARRQGYKGKFEQA
DGGTIFLDEIGEVPPEMQVALLRVLQERTVTPIGSSKEVPVNIRIITATHKDLLRLVEEGKFRQDLYYRLHVYPLYVPSL
IERKEDIPYFIKHFCKRKNWNVVFPKSICNQFSQHTWPGNIRELLNALERIYILSQGREICEKQISFLLQTMMRNQHQLE
LQTENKTENTLNFREKIQRDSMIEALEKTNGNVSLAAKLLDVPRSTFYKRMQKYKL

Specific function: Acts as a transcriptional activator of the acoABCL operon encoding the acetoin dehydrogenase complex [H]

COG id: COG3284

COG function: function code QK; Transcriptional activator of acetoin/glycerol metabolism

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 sigma-54 factor interaction domain [H]

Homologues:

Organism=Escherichia coli, GI1790437, Length=312, Percent_Identity=43.2692307692308, Blast_Score=265, Evalue=6e-72,
Organism=Escherichia coli, GI87082117, Length=326, Percent_Identity=40.7975460122699, Blast_Score=260, Evalue=1e-70,
Organism=Escherichia coli, GI1788905, Length=315, Percent_Identity=41.2698412698413, Blast_Score=255, Evalue=6e-69,
Organism=Escherichia coli, GI1789233, Length=307, Percent_Identity=39.0879478827362, Blast_Score=229, Evalue=3e-61,
Organism=Escherichia coli, GI1788550, Length=320, Percent_Identity=40, Blast_Score=224, Evalue=9e-60,
Organism=Escherichia coli, GI1789087, Length=317, Percent_Identity=38.801261829653, Blast_Score=222, Evalue=7e-59,
Organism=Escherichia coli, GI1790299, Length=350, Percent_Identity=36.2857142857143, Blast_Score=217, Evalue=2e-57,
Organism=Escherichia coli, GI1786524, Length=322, Percent_Identity=38.8198757763975, Blast_Score=212, Evalue=5e-56,
Organism=Escherichia coli, GI87082152, Length=318, Percent_Identity=36.7924528301887, Blast_Score=206, Evalue=2e-54,
Organism=Escherichia coli, GI87081858, Length=645, Percent_Identity=23.8759689922481, Blast_Score=189, Evalue=5e-49,
Organism=Escherichia coli, GI1787583, Length=247, Percent_Identity=38.4615384615385, Blast_Score=182, Evalue=4e-47,
Organism=Escherichia coli, GI87081872, Length=229, Percent_Identity=41.0480349344978, Blast_Score=179, Evalue=5e-46,
Organism=Escherichia coli, GI1789828, Length=322, Percent_Identity=30.4347826086957, Blast_Score=147, Evalue=2e-36,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR020441
- InterPro:   IPR009057
- InterPro:   IPR002197
- InterPro:   IPR002078 [H]

Pfam domain/function: PF02954 HTH_8; PF00158 Sigma54_activat [H]

EC number: NA

Molecular weight: Translated: 70572; Mature: 70572

Theoretical pI: Translated: 8.21; Mature: 8.21

Prosite motif: PS00675 SIGMA54_INTERACT_1 ; PS00676 SIGMA54_INTERACT_2 ; PS00688 SIGMA54_INTERACT_3 ; PS50045 SIGMA54_INTERACT_4

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLASPFYLHTWKKFVDEGVLDSNRINERISESWYRCKQANVNPHMNKGQKILSSNIFQDQ
CCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHH
KKKSEIFLDIAIPQIQNMRKTIDELQMMALLIDPDGYVLSLSGNEQTLKRAKHINFIEGV
HCCCEEEEEEECHHHHHHHHHHHHHHHEEEEECCCCEEEEECCCHHHHHHHHCCCHHHCC
KWTEAAVGTNAIGTALEIEEAIMISGTEHYSVASHSWSCAAAPIHNDDGKLIGVLDFSCP
CHHHHHCCCCCCCCHHEECCEEEEECCCCEEECCCCCCEEECCEECCCCCEEEEEECCCC
IEFSHPYMLGMVTSIAHAIERECSIRVHQNELHLIHRFLDVIDSNEQVVICNHRNVIVSA
CCCCCCHHHHHHHHHHHHHHHCCCEEEECHHHHHHHHHHHHHCCCCEEEEECCCCEEEEH
SKRIRERVTNWSRMKLEDLMYYGLKTKLEVPVYSNNRMIGKCIYVKENKQEKVFSTSLFI
HHHHHHHHCCCHHHHHHHHHHHCCCEEEEEEEECCCEEEEEEEEEECCCCHHHEEEEEEE
NGITFPGVIGTSDAFQHTLEEIKLVSPTDASVYVCGETGVGKEYVARAIHENSPRKNGPF
ECCCCCCCCCCCHHHHHHHHHCEECCCCCCEEEEECCCCCCHHHHHHHHHCCCCCCCCCE
IAVNCGALPKELMESELFGYAEGAFTGARRQGYKGKFEQADGGTIFLDEIGEVPPEMQVA
EEEECCCCCHHHHHHHHCCCCCCCCCCHHHCCCCCCCCCCCCCEEEEHHHCCCCHHHHHH
LLRVLQERTVTPIGSSKEVPVNIRIITATHKDLLRLVEEGKFRQDLYYRLHVYPLYVPSL
HHHHHHHCCCCCCCCCCCCEEEEEEEEECHHHHHHHHHCCCHHHEEEEEEEEEEEHHHHH
IERKEDIPYFIKHFCKRKNWNVVFPKSICNQFSQHTWPGNIRELLNALERIYILSQGREI
HHHCCCCCHHHHHHHCCCCCCEEECHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCHHH
CEKQISFLLQTMMRNQHQLELQTENKTENTLNFREKIQRDSMIEALEKTNGNVSLAAKLL
HHHHHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEHHHHH
DVPRSTFYKRMQKYKL
HCCHHHHHHHHHHCCC
>Mature Secondary Structure
MLASPFYLHTWKKFVDEGVLDSNRINERISESWYRCKQANVNPHMNKGQKILSSNIFQDQ
CCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHH
KKKSEIFLDIAIPQIQNMRKTIDELQMMALLIDPDGYVLSLSGNEQTLKRAKHINFIEGV
HCCCEEEEEEECHHHHHHHHHHHHHHHEEEEECCCCEEEEECCCHHHHHHHHCCCHHHCC
KWTEAAVGTNAIGTALEIEEAIMISGTEHYSVASHSWSCAAAPIHNDDGKLIGVLDFSCP
CHHHHHCCCCCCCCHHEECCEEEEECCCCEEECCCCCCEEECCEECCCCCEEEEEECCCC
IEFSHPYMLGMVTSIAHAIERECSIRVHQNELHLIHRFLDVIDSNEQVVICNHRNVIVSA
CCCCCCHHHHHHHHHHHHHHHCCCEEEECHHHHHHHHHHHHHCCCCEEEEECCCCEEEEH
SKRIRERVTNWSRMKLEDLMYYGLKTKLEVPVYSNNRMIGKCIYVKENKQEKVFSTSLFI
HHHHHHHHCCCHHHHHHHHHHHCCCEEEEEEEECCCEEEEEEEEEECCCCHHHEEEEEEE
NGITFPGVIGTSDAFQHTLEEIKLVSPTDASVYVCGETGVGKEYVARAIHENSPRKNGPF
ECCCCCCCCCCCHHHHHHHHHCEECCCCCCEEEEECCCCCCHHHHHHHHHCCCCCCCCCE
IAVNCGALPKELMESELFGYAEGAFTGARRQGYKGKFEQADGGTIFLDEIGEVPPEMQVA
EEEECCCCCHHHHHHHHCCCCCCCCCCHHHCCCCCCCCCCCCCEEEEHHHCCCCHHHHHH
LLRVLQERTVTPIGSSKEVPVNIRIITATHKDLLRLVEEGKFRQDLYYRLHVYPLYVPSL
HHHHHHHCCCCCCCCCCCCEEEEEEEEECHHHHHHHHHCCCHHHEEEEEEEEEEEHHHHH
IERKEDIPYFIKHFCKRKNWNVVFPKSICNQFSQHTWPGNIRELLNALERIYILSQGREI
HHHCCCCCHHHHHHHCCCCCCEEECHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCHHH
CEKQISFLLQTMMRNQHQLELQTENKTENTLNFREKIQRDSMIEALEKTNGNVSLAAKLL
HHHHHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEHHHHH
DVPRSTFYKRMQKYKL
HCCHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8969503; 9384377; 10368162 [H]