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The map label for this gene is ycxD [H]

Identifier: 218903715

GI number: 218903715

Start: 2471783

End: 2473153

Strand: Direct

Name: ycxD [H]

Synonym: BCAH820_2599

Alternate gene names: 218903715

Gene position: 2471783-2473153 (Clockwise)

Preceding gene: 218903714

Following gene: 218903716

Centisome position: 46.61

GC content: 30.2

Gene sequence:

>1371_bases
ATGTATAAGTATTTACATATTTTAAACGATATAGAAAAAATGATTCAAAATGGAGCGATAAATGAAGGACAGAAATTACC
ATCAATACGGTCACTTGTTACGCAATATGAATGTAATAAGGCGACAGTTATACGTGCGCTTTATGAATTGGAAAAGCGTC
ATATTATATATTCTGTCCCTCAAAGTGGATACTACGTTGTTAAAAAATCAGGGAGTACTATAGAAAATGACAAGATAATT
GATTTCGCTTCTTCAGCACCAGATCCAGATGTTTTCCCATATTTAGATTTTCAGCATTGCATTAATAAGGCTATTGATAC
TTATAAAAATGATTTGTTCGTATATGGAACGCCAAAAGGATTACCATCTTTAATTCCAGTCATTCAAAAACAGTTGGCAA
ATTATCAAGTGTTCACGAAAGAAGACAATATTTTTATAACGTCAGGAGTGCAGCAGGCACTTGCAATATTAACTTCTATA
CCATTTCCAAATAAAAATGAAACAATATTAGTTGAACAACCAACGTATCATTTATATATAGAATATCTAGAAATAAATAA
AGTTCCAGTAATCGGTATTAAACGTACGAGTGAAGGTATTGATTTAAATGAATTGGAGCGTATTTTTCGAACGGGTAAAA
TAAAATTCTTTTATACAATACCAAGATATCATCATCCACTTGGAACTTCTTATTCTAAAGGTGAGAAAGAAAAAGTCGTA
CTATTGGCTAAGAAATATAATGTATTTATAGTGGAAGATGATTATTTAGCAGATTTAGAAACAGATTCAAAAGCCGATCC
GTTATATAGCTTGGATCATGATAATCATGTCATATATTTGAAAAGTTATTCGAAAATTATTTTCCCTGGTTTACGAGTTG
GTGTAGCAGTTATTCCACCGGTTATTTCGAGTGCTTTCCATACATATAAAAAGGTTTTAGATATTGATAGCCCGATGATA
TCCCAAGCTGCTTTAGAAATTTATATAAAGAGTGGTATGTTCGAACGCCATAAAAATAAAATTAAATCTTCCTATAATAA
TAGATCTAAAAAACTAGCTGAAGCATTAGAAAGAATTCATAGTGAAAATCCGCTTTTATTCACATATAAAAAGCAAAATA
CAATTGGAATCCACACTTGTTTAGAATTACACAAAACGAGTATTTCTGAAATGTTATTCCAAAGATTAAATGAAATGCAA
ATATGTATTGATACGATTGATAAAAATTATGTGAGAGGTTTTCCGAAACAAAGACTATTAAAGTTGAACGTATCGAATGT
AAAGGAAGATAGGATTGAAGAAGGAATTCGTAAAGTAATGGAGGAAATCAAACAAGCTGAACGTCTAAATTTTCAATTTA
AAAAAGAATAA

Upstream 100 bases:

>100_bases
TACGATATAGAAAATCGGAAAATTAACTAATTGAGGAGTGGATGGTATATAAATGAAAAGTCGATGTAATTAAATATAGA
ATTGCTGAAGGAGGTGTAAT

Downstream 100 bases:

>100_bases
AATGAATAAGGAGGTTTGTTGTGAGGCGTAAAATAATTCTCTTGTTTGTGTGTATCGCTGTAATAATTGGAGCTATGATT
GTAACGAAATACTATAAAAA

Product: hypothetical protein

Products: NA

Alternate protein names: ORF8 [H]

Number of amino acids: Translated: 456; Mature: 456

Protein sequence:

>456_residues
MYKYLHILNDIEKMIQNGAINEGQKLPSIRSLVTQYECNKATVIRALYELEKRHIIYSVPQSGYYVVKKSGSTIENDKII
DFASSAPDPDVFPYLDFQHCINKAIDTYKNDLFVYGTPKGLPSLIPVIQKQLANYQVFTKEDNIFITSGVQQALAILTSI
PFPNKNETILVEQPTYHLYIEYLEINKVPVIGIKRTSEGIDLNELERIFRTGKIKFFYTIPRYHHPLGTSYSKGEKEKVV
LLAKKYNVFIVEDDYLADLETDSKADPLYSLDHDNHVIYLKSYSKIIFPGLRVGVAVIPPVISSAFHTYKKVLDIDSPMI
SQAALEIYIKSGMFERHKNKIKSSYNNRSKKLAEALERIHSENPLLFTYKKQNTIGIHTCLELHKTSISEMLFQRLNEMQ
ICIDTIDKNYVRGFPKQRLLKLNVSNVKEDRIEEGIRKVMEEIKQAERLNFQFKKE

Sequences:

>Translated_456_residues
MYKYLHILNDIEKMIQNGAINEGQKLPSIRSLVTQYECNKATVIRALYELEKRHIIYSVPQSGYYVVKKSGSTIENDKII
DFASSAPDPDVFPYLDFQHCINKAIDTYKNDLFVYGTPKGLPSLIPVIQKQLANYQVFTKEDNIFITSGVQQALAILTSI
PFPNKNETILVEQPTYHLYIEYLEINKVPVIGIKRTSEGIDLNELERIFRTGKIKFFYTIPRYHHPLGTSYSKGEKEKVV
LLAKKYNVFIVEDDYLADLETDSKADPLYSLDHDNHVIYLKSYSKIIFPGLRVGVAVIPPVISSAFHTYKKVLDIDSPMI
SQAALEIYIKSGMFERHKNKIKSSYNNRSKKLAEALERIHSENPLLFTYKKQNTIGIHTCLELHKTSISEMLFQRLNEMQ
ICIDTIDKNYVRGFPKQRLLKLNVSNVKEDRIEEGIRKVMEEIKQAERLNFQFKKE
>Mature_456_residues
MYKYLHILNDIEKMIQNGAINEGQKLPSIRSLVTQYECNKATVIRALYELEKRHIIYSVPQSGYYVVKKSGSTIENDKII
DFASSAPDPDVFPYLDFQHCINKAIDTYKNDLFVYGTPKGLPSLIPVIQKQLANYQVFTKEDNIFITSGVQQALAILTSI
PFPNKNETILVEQPTYHLYIEYLEINKVPVIGIKRTSEGIDLNELERIFRTGKIKFFYTIPRYHHPLGTSYSKGEKEKVV
LLAKKYNVFIVEDDYLADLETDSKADPLYSLDHDNHVIYLKSYSKIIFPGLRVGVAVIPPVISSAFHTYKKVLDIDSPMI
SQAALEIYIKSGMFERHKNKIKSSYNNRSKKLAEALERIHSENPLLFTYKKQNTIGIHTCLELHKTSISEMLFQRLNEMQ
ICIDTIDKNYVRGFPKQRLLKLNVSNVKEDRIEEGIRKVMEEIKQAERLNFQFKKE

Specific function: Unknown

COG id: COG1167

COG function: function code KE; Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH gntR-type DNA-binding domain [H]

Homologues:

Organism=Homo sapiens, GI7705897, Length=407, Percent_Identity=23.5872235872236, Blast_Score=81, Evalue=2e-15,
Organism=Homo sapiens, GI33469970, Length=407, Percent_Identity=23.5872235872236, Blast_Score=81, Evalue=2e-15,
Organism=Escherichia coli, GI1787710, Length=394, Percent_Identity=25.6345177664975, Blast_Score=127, Evalue=1e-30,
Organism=Escherichia coli, GI1790797, Length=377, Percent_Identity=24.6684350132626, Blast_Score=115, Evalue=5e-27,
Organism=Saccharomyces cerevisiae, GI6321236, Length=211, Percent_Identity=27.0142180094787, Blast_Score=67, Evalue=6e-12,
Organism=Drosophila melanogaster, GI21356535, Length=320, Percent_Identity=25.9375, Blast_Score=83, Evalue=3e-16,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004839
- InterPro:   IPR000524
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00155 Aminotran_1_2; PF00392 GntR [H]

EC number: NA

Molecular weight: Translated: 52723; Mature: 52723

Theoretical pI: Translated: 9.07; Mature: 9.07

Prosite motif: PS50949 HTH_GNTR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYKYLHILNDIEKMIQNGAINEGQKLPSIRSLVTQYECNKATVIRALYELEKRHIIYSVP
CCHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHCCEEEECC
QSGYYVVKKSGSTIENDKIIDFASSAPDPDVFPYLDFQHCINKAIDTYKNDLFVYGTPKG
CCCEEEEECCCCCCCCCCEEEECCCCCCCCCCCCCCHHHHHHHHHHHHCCCEEEEECCCC
LPSLIPVIQKQLANYQVFTKEDNIFITSGVQQALAILTSIPFPNKNETILVEQPTYHLYI
CHHHHHHHHHHHCCCEEEEECCCEEEECCHHHHHHHHHHCCCCCCCCEEEEECCCEEEEE
EYLEINKVPVIGIKRTSEGIDLNELERIFRTGKIKFFYTIPRYHHPLGTSYSKGEKEKVV
EEEEECCEEEEEEECCCCCCCHHHHHHHHHCCCEEEEEECCCCCCCCCCCCCCCCCCEEE
LLAKKYNVFIVEDDYLADLETDSKADPLYSLDHDNHVIYLKSYSKIIFPGLRVGVAVIPP
EEEEECEEEEEECCCEECCCCCCCCCCCEEECCCCEEEEEECCCHHHCCCHHHHHHHHHH
VISSAFHTYKKVLDIDSPMISQAALEIYIKSGMFERHKNKIKSSYNNRSKKLAEALERIH
HHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHCHHHHHHHHHHHHHC
SENPLLFTYKKQNTIGIHTCLELHKTSISEMLFQRLNEMQICIDTIDKNYVRGFPKQRLL
CCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHCCCCHHHEE
KLNVSNVKEDRIEEGIRKVMEEIKQAERLNFQFKKE
EEEHHHCHHHHHHHHHHHHHHHHHHHHHCCCEECCC
>Mature Secondary Structure
MYKYLHILNDIEKMIQNGAINEGQKLPSIRSLVTQYECNKATVIRALYELEKRHIIYSVP
CCHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHCCEEEECC
QSGYYVVKKSGSTIENDKIIDFASSAPDPDVFPYLDFQHCINKAIDTYKNDLFVYGTPKG
CCCEEEEECCCCCCCCCCEEEECCCCCCCCCCCCCCHHHHHHHHHHHHCCCEEEEECCCC
LPSLIPVIQKQLANYQVFTKEDNIFITSGVQQALAILTSIPFPNKNETILVEQPTYHLYI
CHHHHHHHHHHHCCCEEEEECCCEEEECCHHHHHHHHHHCCCCCCCCEEEEECCCEEEEE
EYLEINKVPVIGIKRTSEGIDLNELERIFRTGKIKFFYTIPRYHHPLGTSYSKGEKEKVV
EEEEECCEEEEEEECCCCCCCHHHHHHHHHCCCEEEEEECCCCCCCCCCCCCCCCCCEEE
LLAKKYNVFIVEDDYLADLETDSKADPLYSLDHDNHVIYLKSYSKIIFPGLRVGVAVIPP
EEEEECEEEEEECCCEECCCCCCCCCCCEEECCCCEEEEEECCCHHHCCCHHHHHHHHHH
VISSAFHTYKKVLDIDSPMISQAALEIYIKSGMFERHKNKIKSSYNNRSKKLAEALERIH
HHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHCHHHHHHHHHHHHHC
SENPLLFTYKKQNTIGIHTCLELHKTSISEMLFQRLNEMQICIDTIDKNYVRGFPKQRLL
CCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHCCCCHHHEE
KLNVSNVKEDRIEEGIRKVMEEIKQAERLNFQFKKE
EEEHHHCHHHHHHHHHHHHHHHHHHHHHCCCEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8355609; 8969502; 9384377 [H]