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The map label for this gene is yngJ [H]

Identifier: 218903676

GI number: 218903676

Start: 2435312

End: 2436457

Strand: Direct

Name: yngJ [H]

Synonym: BCAH820_2560

Alternate gene names: 218903676

Gene position: 2435312-2436457 (Clockwise)

Preceding gene: 218903675

Following gene: 218903677

Centisome position: 45.93

GC content: 38.31

Gene sequence:

>1146_bases
ATGGAATTTACTCTAACTCGCGAAAAACAAATGATTAAAGAAATGGTACGTGACTTTGCTGAAAAGGAAATCGCACCGAA
AGCTGTGTATTATGACAAAACTGCAGAGTTTCCATATGAAACATTTCAAAAAATGGGCGAACTAGGATTATTAGGCATCC
CATTCCCAGAAGAGTATGGAGGTTCAGGTGGCGATACAGTATCGTACGCGTTAGCAGTTGAAGAAATTGGTCGTGCTTGT
GGTGGAACAGGATTAAGTTACGCTGCAACAATTTCATTAGGTGCTTCTCCAATTTATTATTTCGGTACAGAAGAACAAAA
ACAGAAATATTTAGTTCAAATGGCATCAGGCAAAACTTTAGGTGCTTTCGGATTAACTGAGCCGAATGCTGGATCTGATG
CAGGTGGTACACAAACGAAAGCTATATTAGATGGAGACGAGTATGTTATTAGTGGTGAGAAGTGTTGGATTACAAATGCT
GAGTATGCAAATACAATTATTGTAACCGCTGTCAACGGTGTTGAAGAGAATGGTAGAAAACGTATTTCTGCATTTATCGT
ACCGACTACTAGTGAAGGGTTAACGATTTCAAGCCCTTACGATAAGATGGGCGTACGTGCTTCTAATACTTGTGAAATCG
TACTTGATGGTGTACGTGTACCGAAAGAAAATATTCTTGGTGATGTAAATAAAGGATTTAAACAATTCTTATATACACTT
GATGGAGGACGTATTTCAATCGCAGCATTAGCTGTTGGTATTGCACAATCTGCATTTGAACGTGCATTGCAATATGCGAA
AGAACGTCAACAATTTGGAAAGGCAATTTCTAATTTCCAAGCGATTCAATTTAAATTAGCTGATATGGCGACTGAAGTAG
AGCTAGCACGTAATTTAGTACATAAAGCAGCTTGGTTAAAAGATAACGATAAACCTTTCGGTAAAGAAGCGGCTATGGCA
AAACTTTTCGCATCTGAGGCTGCTAGTCGTATTGCAAATCAAGCGGTACAAATTCACGGTGGATACGGCTATATGCGTGA
ATATGAAGTAGAACGACATATTCGTGATGCAAAACTATTAGAAATTGGTGAAGGAACTTCTGAAATTCAACGTCTCGTAA
TTGCTAGACATTTAGGATGTAGATAA

Upstream 100 bases:

>100_bases
CAATTATCTAACTAATGTTCTTGTCTTTTCATTCGTAATGTTTATAGTAGAAACTCGCACGCTGTCGAAACTCAATATTC
GATAAGGGGTGTGTAGCGGA

Downstream 100 bases:

>100_bases
AAAGGAGGAATCACTATGTTTCAAAAAATATTAATTGCTAATCGCGGGGAAATCGCAGTTCGTATTATGAAAACTTGTCA
AAAACTTGGCATTCGTACTG

Product: acyl-CoA dehydrogenase

Products: 2,3-dehydroacyl-CoA; reduced acceptor

Alternate protein names: NA

Number of amino acids: Translated: 381; Mature: 381

Protein sequence:

>381_residues
MEFTLTREKQMIKEMVRDFAEKEIAPKAVYYDKTAEFPYETFQKMGELGLLGIPFPEEYGGSGGDTVSYALAVEEIGRAC
GGTGLSYAATISLGASPIYYFGTEEQKQKYLVQMASGKTLGAFGLTEPNAGSDAGGTQTKAILDGDEYVISGEKCWITNA
EYANTIIVTAVNGVEENGRKRISAFIVPTTSEGLTISSPYDKMGVRASNTCEIVLDGVRVPKENILGDVNKGFKQFLYTL
DGGRISIAALAVGIAQSAFERALQYAKERQQFGKAISNFQAIQFKLADMATEVELARNLVHKAAWLKDNDKPFGKEAAMA
KLFASEAASRIANQAVQIHGGYGYMREYEVERHIRDAKLLEIGEGTSEIQRLVIARHLGCR

Sequences:

>Translated_381_residues
MEFTLTREKQMIKEMVRDFAEKEIAPKAVYYDKTAEFPYETFQKMGELGLLGIPFPEEYGGSGGDTVSYALAVEEIGRAC
GGTGLSYAATISLGASPIYYFGTEEQKQKYLVQMASGKTLGAFGLTEPNAGSDAGGTQTKAILDGDEYVISGEKCWITNA
EYANTIIVTAVNGVEENGRKRISAFIVPTTSEGLTISSPYDKMGVRASNTCEIVLDGVRVPKENILGDVNKGFKQFLYTL
DGGRISIAALAVGIAQSAFERALQYAKERQQFGKAISNFQAIQFKLADMATEVELARNLVHKAAWLKDNDKPFGKEAAMA
KLFASEAASRIANQAVQIHGGYGYMREYEVERHIRDAKLLEIGEGTSEIQRLVIARHLGCR
>Mature_381_residues
MEFTLTREKQMIKEMVRDFAEKEIAPKAVYYDKTAEFPYETFQKMGELGLLGIPFPEEYGGSGGDTVSYALAVEEIGRAC
GGTGLSYAATISLGASPIYYFGTEEQKQKYLVQMASGKTLGAFGLTEPNAGSDAGGTQTKAILDGDEYVISGEKCWITNA
EYANTIIVTAVNGVEENGRKRISAFIVPTTSEGLTISSPYDKMGVRASNTCEIVLDGVRVPKENILGDVNKGFKQFLYTL
DGGRISIAALAVGIAQSAFERALQYAKERQQFGKAISNFQAIQFKLADMATEVELARNLVHKAAWLKDNDKPFGKEAAMA
KLFASEAASRIANQAVQIHGGYGYMREYEVERHIRDAKLLEIGEGTSEIQRLVIARHLGCR

Specific function: Unknown

COG id: COG1960

COG function: function code I; Acyl-CoA dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI4557233, Length=375, Percent_Identity=50.4, Blast_Score=363, Evalue=1e-100,
Organism=Homo sapiens, GI4501859, Length=375, Percent_Identity=40.8, Blast_Score=277, Evalue=9e-75,
Organism=Homo sapiens, GI4557231, Length=376, Percent_Identity=42.2872340425532, Blast_Score=272, Evalue=5e-73,
Organism=Homo sapiens, GI187960098, Length=376, Percent_Identity=42.2872340425532, Blast_Score=271, Evalue=5e-73,
Organism=Homo sapiens, GI226958412, Length=375, Percent_Identity=38.6666666666667, Blast_Score=270, Evalue=1e-72,
Organism=Homo sapiens, GI226958414, Length=338, Percent_Identity=39.9408284023669, Blast_Score=253, Evalue=2e-67,
Organism=Homo sapiens, GI21361497, Length=367, Percent_Identity=40.0544959128065, Blast_Score=249, Evalue=3e-66,
Organism=Homo sapiens, GI4557235, Length=379, Percent_Identity=38.5224274406332, Blast_Score=245, Evalue=5e-65,
Organism=Homo sapiens, GI76496475, Length=379, Percent_Identity=38.5224274406332, Blast_Score=245, Evalue=5e-65,
Organism=Homo sapiens, GI4501857, Length=376, Percent_Identity=35.1063829787234, Blast_Score=236, Evalue=2e-62,
Organism=Homo sapiens, GI7656849, Length=375, Percent_Identity=33.0666666666667, Blast_Score=220, Evalue=2e-57,
Organism=Homo sapiens, GI4503943, Length=378, Percent_Identity=35.7142857142857, Blast_Score=212, Evalue=5e-55,
Organism=Homo sapiens, GI7669494, Length=355, Percent_Identity=36.3380281690141, Blast_Score=202, Evalue=4e-52,
Organism=Homo sapiens, GI48976061, Length=335, Percent_Identity=28.6567164179104, Blast_Score=123, Evalue=3e-28,
Organism=Homo sapiens, GI211971008, Length=335, Percent_Identity=28.6567164179104, Blast_Score=123, Evalue=4e-28,
Organism=Homo sapiens, GI38505218, Length=396, Percent_Identity=27.7777777777778, Blast_Score=120, Evalue=1e-27,
Organism=Homo sapiens, GI218563752, Length=238, Percent_Identity=30.2521008403361, Blast_Score=74, Evalue=3e-13,
Organism=Escherichia coli, GI87081958, Length=381, Percent_Identity=32.2834645669291, Blast_Score=192, Evalue=4e-50,
Organism=Escherichia coli, GI1786223, Length=379, Percent_Identity=29.8153034300792, Blast_Score=183, Evalue=1e-47,
Organism=Escherichia coli, GI87081702, Length=335, Percent_Identity=25.3731343283582, Blast_Score=75, Evalue=8e-15,
Organism=Escherichia coli, GI87082384, Length=327, Percent_Identity=25.3822629969419, Blast_Score=69, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI17534899, Length=382, Percent_Identity=40.5759162303665, Blast_Score=275, Evalue=4e-74,
Organism=Caenorhabditis elegans, GI17569725, Length=382, Percent_Identity=40.3141361256544, Blast_Score=274, Evalue=7e-74,
Organism=Caenorhabditis elegans, GI17570075, Length=383, Percent_Identity=40.2088772845953, Blast_Score=273, Evalue=2e-73,
Organism=Caenorhabditis elegans, GI17508101, Length=372, Percent_Identity=40.3225806451613, Blast_Score=266, Evalue=9e-72,
Organism=Caenorhabditis elegans, GI17538396, Length=380, Percent_Identity=38.6842105263158, Blast_Score=266, Evalue=2e-71,
Organism=Caenorhabditis elegans, GI17506239, Length=372, Percent_Identity=40.0537634408602, Blast_Score=266, Evalue=2e-71,
Organism=Caenorhabditis elegans, GI17533517, Length=375, Percent_Identity=35.4666666666667, Blast_Score=234, Evalue=6e-62,
Organism=Caenorhabditis elegans, GI71990804, Length=307, Percent_Identity=42.0195439739414, Blast_Score=226, Evalue=1e-59,
Organism=Caenorhabditis elegans, GI17534353, Length=374, Percent_Identity=34.4919786096257, Blast_Score=225, Evalue=2e-59,
Organism=Caenorhabditis elegans, GI71985184, Length=381, Percent_Identity=35.4330708661417, Blast_Score=224, Evalue=4e-59,
Organism=Caenorhabditis elegans, GI17551932, Length=359, Percent_Identity=29.8050139275766, Blast_Score=187, Evalue=1e-47,
Organism=Caenorhabditis elegans, GI17505929, Length=358, Percent_Identity=29.3296089385475, Blast_Score=185, Evalue=3e-47,
Organism=Caenorhabditis elegans, GI32563615, Length=232, Percent_Identity=40.5172413793103, Blast_Score=174, Evalue=5e-44,
Organism=Caenorhabditis elegans, GI71985192, Length=328, Percent_Identity=33.8414634146341, Blast_Score=173, Evalue=1e-43,
Organism=Caenorhabditis elegans, GI71982178, Length=272, Percent_Identity=36.0294117647059, Blast_Score=167, Evalue=7e-42,
Organism=Caenorhabditis elegans, GI17531909, Length=241, Percent_Identity=34.4398340248963, Blast_Score=132, Evalue=4e-31,
Organism=Caenorhabditis elegans, GI17562446, Length=330, Percent_Identity=30.3030303030303, Blast_Score=116, Evalue=2e-26,
Organism=Caenorhabditis elegans, GI17531913, Length=178, Percent_Identity=34.2696629213483, Blast_Score=98, Evalue=8e-21,
Organism=Caenorhabditis elegans, GI86563383, Length=273, Percent_Identity=27.4725274725275, Blast_Score=76, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI86563381, Length=273, Percent_Identity=27.4725274725275, Blast_Score=76, Evalue=3e-14,
Organism=Drosophila melanogaster, GI21356377, Length=371, Percent_Identity=47.1698113207547, Blast_Score=347, Evalue=5e-96,
Organism=Drosophila melanogaster, GI24646207, Length=385, Percent_Identity=45.4545454545455, Blast_Score=322, Evalue=3e-88,
Organism=Drosophila melanogaster, GI24660351, Length=378, Percent_Identity=42.0634920634921, Blast_Score=278, Evalue=5e-75,
Organism=Drosophila melanogaster, GI21355753, Length=381, Percent_Identity=40.6824146981627, Blast_Score=274, Evalue=6e-74,
Organism=Drosophila melanogaster, GI24666513, Length=372, Percent_Identity=41.6666666666667, Blast_Score=271, Evalue=4e-73,
Organism=Drosophila melanogaster, GI281363737, Length=380, Percent_Identity=35.2631578947368, Blast_Score=218, Evalue=8e-57,
Organism=Drosophila melanogaster, GI19920834, Length=382, Percent_Identity=35.3403141361257, Blast_Score=203, Evalue=2e-52,
Organism=Drosophila melanogaster, GI221473076, Length=226, Percent_Identity=27.8761061946903, Blast_Score=74, Evalue=1e-13,
Organism=Drosophila melanogaster, GI45550141, Length=226, Percent_Identity=27.8761061946903, Blast_Score=74, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006089
- InterPro:   IPR006092
- InterPro:   IPR006090
- InterPro:   IPR006091
- InterPro:   IPR009075
- InterPro:   IPR013786
- InterPro:   IPR009100 [H]

Pfam domain/function: PF00441 Acyl-CoA_dh_1; PF02770 Acyl-CoA_dh_M; PF02771 Acyl-CoA_dh_N [H]

EC number: 1.3.99.3

Molecular weight: Translated: 41622; Mature: 41622

Theoretical pI: Translated: 5.37; Mature: 5.37

Prosite motif: PS00072 ACYL_COA_DH_1 ; PS00073 ACYL_COA_DH_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEFTLTREKQMIKEMVRDFAEKEIAPKAVYYDKTAEFPYETFQKMGELGLLGIPFPEEYG
CCCCCHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCHHHHHHHCCCCEECCCCCHHHC
GSGGDTVSYALAVEEIGRACGGTGLSYAATISLGASPIYYFGTEEQKQKYLVQMASGKTL
CCCCCHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCEEEECCCHHHHHHHHHHHCCCEE
GAFGLTEPNAGSDAGGTQTKAILDGDEYVISGEKCWITNAEYANTIIVTAVNGVEENGRK
EECCCCCCCCCCCCCCCCEEEEECCCCEEEECCEEEEECCCCCCEEEEEEECCCCCCCCE
RISAFIVPTTSEGLTISSPYDKMGVRASNTCEIVLDGVRVPKENILGDVNKGFKQFLYTL
EEEEEEEEECCCCEEEECCHHHHCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHC
DGGRISIAALAVGIAQSAFERALQYAKERQQFGKAISNFQAIQFKLADMATEVELARNLV
CCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
HKAAWLKDNDKPFGKEAAMAKLFASEAASRIANQAVQIHGGYGYMREYEVERHIRDAKLL
HHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHEEEEECCCCCHHHHHHHHHHCCCCEE
EIGEGTSEIQRLVIARHLGCR
EECCCHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MEFTLTREKQMIKEMVRDFAEKEIAPKAVYYDKTAEFPYETFQKMGELGLLGIPFPEEYG
CCCCCHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCHHHHHHHCCCCEECCCCCHHHC
GSGGDTVSYALAVEEIGRACGGTGLSYAATISLGASPIYYFGTEEQKQKYLVQMASGKTL
CCCCCHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCEEEECCCHHHHHHHHHHHCCCEE
GAFGLTEPNAGSDAGGTQTKAILDGDEYVISGEKCWITNAEYANTIIVTAVNGVEENGRK
EECCCCCCCCCCCCCCCCEEEEECCCCEEEECCEEEEECCCCCCEEEEEEECCCCCCCCE
RISAFIVPTTSEGLTISSPYDKMGVRASNTCEIVLDGVRVPKENILGDVNKGFKQFLYTL
EEEEEEEEECCCCEEEECCHHHHCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHC
DGGRISIAALAVGIAQSAFERALQYAKERQQFGKAISNFQAIQFKLADMATEVELARNLV
CCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
HKAAWLKDNDKPFGKEAAMAKLFASEAASRIANQAVQIHGGYGYMREYEVERHIRDAKLL
HHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHEEEEECCCCCHHHHHHHHHHCCCCEE
EIGEGTSEIQRLVIARHLGCR
EECCCHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: acyl-CoA; acceptor

Specific reaction: acyl-CoA + acceptor = 2,3-dehydroacyl-CoA + reduced acceptor

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9387222; 9384377 [H]