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The map label for this gene is yrbE [H]

Identifier: 218903642

GI number: 218903642

Start: 2397940

End: 2398803

Strand: Direct

Name: yrbE [H]

Synonym: BCAH820_2526

Alternate gene names: 218903642

Gene position: 2397940-2398803 (Clockwise)

Preceding gene: 218903640

Following gene: 218903643

Centisome position: 45.22

GC content: 38.12

Gene sequence:

>864_bases
ATGAACGTTTTAAAGATTGGGATTATTGGTGCTGGACGAATTGGGAAACTACATGTTGATAATTTGCAGCTTATGCCACA
AGTGAAAATTAAAGCGGTTTCAGATGTAGTAATTGGTCATCTAGAAAAGTGGGCTCAAGATAAAGGAATTTCCACTCTGA
STACAAACTATCAGGATTTATTAGCAGATCCAGAAATTGATGCTGTCTTTATTTGTTCACCAACAAATACACATGCGCAA
ATTATTAAAGAAGCGGCTCTTGCGAAAAAACATATTTTCTGTGAAAAGCCTGTTAGTTTCTCAGTAGAAGAAACATTAGA
AGCATTAGAAGTGGTGAAAGAACAGGGGGTATCTCTTCAAGTAGGTTTTAATCGTCGTTTTGATCCGAACTTCAGGAAAG
TTTATGATCTTATTCAACAAGGAGAAGTGGGACAGCCGCATATTTTAAAAATTACGTCACGCGATCCACAACCGCCAAGT
ATAGAATATGTTCGCTCTTCAGGCGGATTGTTTATGGACATGATGATTCATGATTTTGATATGGCTCGTTATGTGATGAA
TAGTGAAGTCGTTGAAGTATTTGCATATGGAACAACATTAATTGATCCATCCATTCAGGAAGTACATGATGTTGATACTG
CAATTGTCACATTAAAATTTGCGAATGGAGCTTTAGGTGTAATTGATAATAGCCGCCAAGCTGTTTATGGATATGACCAG
CGTGTGGAAGTGTTTGGTGAAAAAGGCGCGGTTGCTGCGGATAATTGCTGCCCGACAACAGTTCAAGTGTCAAAAACAGA
AGGTATTGTAAAAGATAAGCCGCTTTATTTCTTCTTAGAGCGTTACACGGCAGGCTTACATTGA

Upstream 100 bases:

>100_bases
AATGAAGAAAAATAGGGAAAGCGCTTAACTTAATTTAATATGCTAAACCCTATAGACTTTCATTTTGTTTCTTAAATTTT
AATATAGAGGGAGAAATCAT

Downstream 100 bases:

>100_bases
GGAAGTAACACAATTTACAAAGTCAATTATAGAAGGACAAGCTGTTATTTGCAGTGGTAATGATGGGTTACAAGCGGAGC
GAATTGCGAAAGCTGCGAAG

Product: oxidoreductase, NAD-binding

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 287; Mature: 287

Protein sequence:

>287_residues
MNVLKIGIIGAGRIGKLHVDNLQLMPQVKIKAVSDVVIGHLEKWAQDKGISTLXTNYQDLLADPEIDAVFICSPTNTHAQ
IIKEAALAKKHIFCEKPVSFSVEETLEALEVVKEQGVSLQVGFNRRFDPNFRKVYDLIQQGEVGQPHILKITSRDPQPPS
IEYVRSSGGLFMDMMIHDFDMARYVMNSEVVEVFAYGTTLIDPSIQEVHDVDTAIVTLKFANGALGVIDNSRQAVYGYDQ
RVEVFGEKGAVAADNCCPTTVQVSKTEGIVKDKPLYFFLERYTAGLH

Sequences:

>Translated_287_residues
MNVLKIGIIGAGRIGKLHVDNLQLMPQVKIKAVSDVVIGHLEKWAQDKGISTLXTNYQDLLADPEIDAVFICSPTNTHAQ
IIKEAALAKKHIFCEKPVSFSVEETLEALEVVKEQGVSLQVGFNRRFDPNFRKVYDLIQQGEVGQPHILKITSRDPQPPS
IEYVRSSGGLFMDMMIHDFDMARYVMNSEVVEVFAYGTTLIDPSIQEVHDVDTAIVTLKFANGALGVIDNSRQAVYGYDQ
RVEVFGEKGAVAADNCCPTTVQVSKTEGIVKDKPLYFFLERYTAGLH
>Mature_287_residues
MNVLKIGIIGAGRIGKLHVDNLQLMPQVKIKAVSDVVIGHLEKWAQDKGISTLXTNYQDLLADPEIDAVFICSPTNTHAQ
IIKEAALAKKHIFCEKPVSFSVEETLEALEVVKEQGVSLQVGFNRRFDPNFRKVYDLIQQGEVGQPHILKITSRDPQPPS
IEYVRSSGGLFMDMMIHDFDMARYVMNSEVVEVFAYGTTLIDPSIQEVHDVDTAIVTLKFANGALGVIDNSRQAVYGYDQ
RVEVFGEKGAVAADNCCPTTVQVSKTEGIVKDKPLYFFLERYTAGLH

Specific function: Unknown

COG id: COG0673

COG function: function code R; Predicted dehydrogenases and related proteins

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the gfo/idh/mocA family [H]

Homologues:

Organism=Escherichia coli, GI87082405, Length=257, Percent_Identity=23.7354085603113, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1787574, Length=247, Percent_Identity=24.6963562753036, Blast_Score=71, Evalue=8e-14,
Organism=Escherichia coli, GI87081947, Length=184, Percent_Identity=26.0869565217391, Blast_Score=64, Evalue=8e-12,
Organism=Drosophila melanogaster, GI24581117, Length=200, Percent_Identity=22.5, Blast_Score=69, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016040
- InterPro:   IPR000683
- InterPro:   IPR004104 [H]

Pfam domain/function: PF01408 GFO_IDH_MocA; PF02894 GFO_IDH_MocA_C [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 31816; Mature: 31816

Theoretical pI: Translated: 5.37; Mature: 5.37

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNVLKIGIIGAGRIGKLHVDNLQLMPQVKIKAVSDVVIGHLEKWAQDKGISTLXTNYQDL
CCEEEEEEEECCCCCEEEECCEEECCCCHHHHHHHHHHHHHHHHHHHCCCHHHHCCHHHH
LADPEIDAVFICSPTNTHAQIIKEAALAKKHIFCEKPVSFSVEETLEALEVVKEQGVSLQ
HCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHEECCCCCCCHHHHHHHHHHHHHCCCEEE
VGFNRRFDPNFRKVYDLIQQGEVGQPHILKITSRDPQPPSIEYVRSSGGLFMDMMIHDFD
ECCCCCCCCCHHHHHHHHHCCCCCCCEEEEEECCCCCCCCHHEEECCCCEEEEHHHHHHH
MARYVMNSEVVEVFAYGTTLIDPSIQEVHDVDTAIVTLKFANGALGVIDNSRQAVYGYDQ
HHHHHHHHHHEEEEECCCEEECCCHHHHHCCCEEEEEEEECCCEEEEEECCCCEEECCCC
RVEVFGEKGAVAADNCCPTTVQVSKTEGIVKDKPLYFFLERYTAGLH
EEEEECCCCCEEECCCCCCEEEEECCCCCCCCCCHHEEEEHHHCCCC
>Mature Secondary Structure
MNVLKIGIIGAGRIGKLHVDNLQLMPQVKIKAVSDVVIGHLEKWAQDKGISTLXTNYQDL
CCEEEEEEEECCCCCEEEECCEEECCCCHHHHHHHHHHHHHHHHHHHCCCHHHHCCHHHH
LADPEIDAVFICSPTNTHAQIIKEAALAKKHIFCEKPVSFSVEETLEALEVVKEQGVSLQ
HCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHEECCCCCCCHHHHHHHHHHHHHCCCEEE
VGFNRRFDPNFRKVYDLIQQGEVGQPHILKITSRDPQPPSIEYVRSSGGLFMDMMIHDFD
ECCCCCCCCCHHHHHHHHHCCCCCCCEEEEEECCCCCCCCHHEEECCCCEEEEHHHHHHH
MARYVMNSEVVEVFAYGTTLIDPSIQEVHDVDTAIVTLKFANGALGVIDNSRQAVYGYDQ
HHHHHHHHHHEEEEECCCEEECCCHHHHHCCCEEEEEEEECCCEEEEEECCCCEEECCCC
RVEVFGEKGAVAADNCCPTTVQVSKTEGIVKDKPLYFFLERYTAGLH
EEEEECCCCCEEECCCCCCEEEEECCCCCCCCCCHHEEEEHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377; 9025289 [H]