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The map label for this gene is licC [H]

Identifier: 218903596

GI number: 218903596

Start: 2356913

End: 2358196

Strand: Direct

Name: licC [H]

Synonym: BCAH820_2480

Alternate gene names: 218903596

Gene position: 2356913-2358196 (Clockwise)

Preceding gene: 218903595

Following gene: 218903597

Centisome position: 44.45

GC content: 35.75

Gene sequence:

>1284_bases
ATGAATAAGTTTGTCACGTTTCTTGATAAAAACTTATCTGGACCGATGGCAAGACTTTCTGAACAGAGACATTTACAAGC
AATCCGTGATGGAGTTATTTCAGCATTACCATTTATCATCGTAGGAAGTTTCTTTTTAATCGTAGCATTTCCACCATTAC
CGAAAGATAGTTTCATATCCGTTTGGGCATTAAAAAATCAAACAAGTATATTAATACCATATCGTTTGACGATGTTTATT
ATGTCTTTATATATAGCATTTGGAATAGGATATAATTTAGCGAAGAGTTATAAGTTAGATGCTTTATCGGGAGCTCAGCT
TGCAGTATGTTCACTGCTATTAACATTAACTCCTGAATTAATTGATAAAAAAGGATTTATGCTTCCGATGACAAATCTCG
GAGGGCATGGATTATTCGTGACTATGATTGTTTCTATTTTATCAGTTGAGATTTTAAGATTTTGTAAGAAGAACAACGTA
ACAATCAAAATGCCAGAACAAGTACCACCTTCAGTATCGCGTTCGTTTGAAGCACTTATACCTGCTGCATTCGTTATTAT
TATTATGAGCCTTATTACAGTTGTTTTTAAAGTTGATGTACATTACGTAGTGGATAAATTAGCCGCACCGTTAGTCAAAG
CTGGAGATAGTTACTTTGGCGTTATAATACCTGTATTTTTAATTACATTTTTCTGGTCCTTCGGAATACATGGTGTATCG
GTTGTAGGTACTGTAGCAAGACCGCTTTGGGATGTATATTTAGGGAAAAATGGTGAAGCTGTAGCAAGTGGTGCGAGTCA
ATTTCCATTCATTGCACCAGAACCGTTTTATCAATGGTTTATTTGGATTGGTGGTTCGGGTGCAACGTTAGGGCTTGTGT
TAGCAATGATCGTATTTGGTCGATCAAAATATTCGAAGGCATTATCGAGAACTTGTATTGTGCCTGGGATTTTTAATATT
AATGAACCAGTTATATTCGGCTTGCCGATTGTATTGAATCCAATTTTAATTATTCCTTTCGTCATTACGCCGCTAGTAAC
AGCGACTATCGCTTATGCTGCAACTGCAATGGGATTTGTAACGCCAACTCATATTATGCCGCCATGGACATTACCAGCCC
CAATTGGTGCATATTTAGCTACAGGAGGAGATTGGCGTGCAATTGTATTAGTCTTAATAAATATAGCAATATCATTCCTT
ATTTATTTACCATTCTTTAAAATGTACGACAAAAATATGCTTGAAATTGAGAAGAATGGTGAAGGAGAATCTGTTAATCC
ATAA

Upstream 100 bases:

>100_bases
CTATTCCGTGTGGTATCATTCCGCCGCAAGCATATACGCCACTTGGCGGACCGACTTTATTAAAGACTGTAAATGATTTA
ATTCGTTAGGGGGAACCGTT

Downstream 100 bases:

>100_bases
TCTTTATGCTTTATTTTGTGAGTGATAGGCATTTTGTCTATCACTTCTTTCACATTAAGTTGAGAGAGGGTGAAATGGAA
TGAATATAAAATTTAGTTAT

Product: putative PTS system, cellobiose-specific IIC component

Products: protein histidine; sugar phosphate

Alternate protein names: EIIC-Lic; PTS system lichenan-specific EIIC component [H]

Number of amino acids: Translated: 427; Mature: 427

Protein sequence:

>427_residues
MNKFVTFLDKNLSGPMARLSEQRHLQAIRDGVISALPFIIVGSFFLIVAFPPLPKDSFISVWALKNQTSILIPYRLTMFI
MSLYIAFGIGYNLAKSYKLDALSGAQLAVCSLLLTLTPELIDKKGFMLPMTNLGGHGLFVTMIVSILSVEILRFCKKNNV
TIKMPEQVPPSVSRSFEALIPAAFVIIIMSLITVVFKVDVHYVVDKLAAPLVKAGDSYFGVIIPVFLITFFWSFGIHGVS
VVGTVARPLWDVYLGKNGEAVASGASQFPFIAPEPFYQWFIWIGGSGATLGLVLAMIVFGRSKYSKALSRTCIVPGIFNI
NEPVIFGLPIVLNPILIIPFVITPLVTATIAYAATAMGFVTPTHIMPPWTLPAPIGAYLATGGDWRAIVLVLINIAISFL
IYLPFFKMYDKNMLEIEKNGEGESVNP

Sequences:

>Translated_427_residues
MNKFVTFLDKNLSGPMARLSEQRHLQAIRDGVISALPFIIVGSFFLIVAFPPLPKDSFISVWALKNQTSILIPYRLTMFI
MSLYIAFGIGYNLAKSYKLDALSGAQLAVCSLLLTLTPELIDKKGFMLPMTNLGGHGLFVTMIVSILSVEILRFCKKNNV
TIKMPEQVPPSVSRSFEALIPAAFVIIIMSLITVVFKVDVHYVVDKLAAPLVKAGDSYFGVIIPVFLITFFWSFGIHGVS
VVGTVARPLWDVYLGKNGEAVASGASQFPFIAPEPFYQWFIWIGGSGATLGLVLAMIVFGRSKYSKALSRTCIVPGIFNI
NEPVIFGLPIVLNPILIIPFVITPLVTATIAYAATAMGFVTPTHIMPPWTLPAPIGAYLATGGDWRAIVLVLINIAISFL
IYLPFFKMYDKNMLEIEKNGEGESVNP
>Mature_427_residues
MNKFVTFLDKNLSGPMARLSEQRHLQAIRDGVISALPFIIVGSFFLIVAFPPLPKDSFISVWALKNQTSILIPYRLTMFI
MSLYIAFGIGYNLAKSYKLDALSGAQLAVCSLLLTLTPELIDKKGFMLPMTNLGGHGLFVTMIVSILSVEILRFCKKNNV
TIKMPEQVPPSVSRSFEALIPAAFVIIIMSLITVVFKVDVHYVVDKLAAPLVKAGDSYFGVIIPVFLITFFWSFGIHGVS
VVGTVARPLWDVYLGKNGEAVASGASQFPFIAPEPFYQWFIWIGGSGATLGLVLAMIVFGRSKYSKALSRTCIVPGIFNI
NEPVIFGLPIVLNPILIIPFVITPLVTATIAYAATAMGFVTPTHIMPPWTLPAPIGAYLATGGDWRAIVLVLINIAISFL
IYLPFFKMYDKNMLEIEKNGEGESVNP

Specific function: The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane. This system i

COG id: COG1455

COG function: function code G; Phosphotransferase system cellobiose-specific component IIC

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PTS EIIC type-3 domain [H]

Homologues:

Organism=Escherichia coli, GI1788032, Length=450, Percent_Identity=31.3333333333333, Blast_Score=206, Evalue=2e-54,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003352
- InterPro:   IPR004796
- InterPro:   IPR004501 [H]

Pfam domain/function: PF02378 PTS_EIIC [H]

EC number: 2.7.1.69

Molecular weight: Translated: 46795; Mature: 46795

Theoretical pI: Translated: 9.48; Mature: 9.48

Prosite motif: PS51105 PTS_EIIC_TYPE_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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CCCCCCC
>Mature Secondary Structure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CCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: protein N(pi)-phosphohistidine; sugar

Specific reaction: protein N(pi)-phosphohistidine + sugar = protein histidine + sugar phosphate

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8990303; 8969509; 9384377 [H]