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The map label for this gene is mdmC [H]

Identifier: 218903590

GI number: 218903590

Start: 2351887

End: 2352471

Strand: Direct

Name: mdmC [H]

Synonym: BCAH820_2474

Alternate gene names: 218903590

Gene position: 2351887-2352471 (Clockwise)

Preceding gene: 218903588

Following gene: 218903591

Centisome position: 44.35

GC content: 34.02

Gene sequence:

>585_bases
ATGGATACATTAAATTCATTATTATTTCAACTTGAACAATATGGAGAAGAGCATGATCGAAATAAAAAAACACGGGAAGA
AAAATTACGGAATATTTCTCGTGAGATGGGGCAATTTTTATCAATTTTAGTAAAAGGGTGTAGTGCAAAAAACATTTTAG
AAATTGGAACTTCTAATGGTTATTCTACATTGTGGTTAGCTGATGCGGTAGAAGAAACAAATGGAAATGTAACAACTGTA
GAGCTTTCCTCAGAACGAGTTGGAGAGGCACTTGCCAATTTTGAAAACGCAAACCTTTTACAAAGGATTGATGTTCACAA
TCAAGAAGCAGGGGCATTTTTAGATTCACAACTAGATCATTCATTTGATTTTATTTTCCTAGATTCAGAGCGTACGCAAT
ACATGTGGTGGCTTGAGCATATAAAACGCATTTTACAACCAAAAGGTCTTCTTGTTGTCGATAATGCTACTTCTCATGCG
AATGAATTAGCTGAGTTTATAAAAATGATTGAAGAAGATAAAATGTTTGAAACAGTGTTATTGGCATTTCAAAATGGTGC
ATTTGTAGCGCGTAAGAAGCAATAG

Upstream 100 bases:

>100_bases
GTCATATAACGGGAAAAAGGATTTCGTTTCGCATATAATAAAAAGTAGACGGGCAACAAGAGCTTTTTCATCATATTGCT
TTAGAAAGGCGATGAAAAGA

Downstream 100 bases:

>100_bases
GATTGAACGCAATATAATTATCACATTGAAAAAGGGTGTATGTCAAAAGATTGAGTACAGTAGGATGGGAAGGACGTAAT
TTATATATGTAACATACGAA

Product: O-methyltransferase family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 194; Mature: 194

Protein sequence:

>194_residues
MDTLNSLLFQLEQYGEEHDRNKKTREEKLRNISREMGQFLSILVKGCSAKNILEIGTSNGYSTLWLADAVEETNGNVTTV
ELSSERVGEALANFENANLLQRIDVHNQEAGAFLDSQLDHSFDFIFLDSERTQYMWWLEHIKRILQPKGLLVVDNATSHA
NELAEFIKMIEEDKMFETVLLAFQNGAFVARKKQ

Sequences:

>Translated_194_residues
MDTLNSLLFQLEQYGEEHDRNKKTREEKLRNISREMGQFLSILVKGCSAKNILEIGTSNGYSTLWLADAVEETNGNVTTV
ELSSERVGEALANFENANLLQRIDVHNQEAGAFLDSQLDHSFDFIFLDSERTQYMWWLEHIKRILQPKGLLVVDNATSHA
NELAEFIKMIEEDKMFETVLLAFQNGAFVARKKQ
>Mature_194_residues
MDTLNSLLFQLEQYGEEHDRNKKTREEKLRNISREMGQFLSILVKGCSAKNILEIGTSNGYSTLWLADAVEETNGNVTTV
ELSSERVGEALANFENANLLQRIDVHNQEAGAFLDSQLDHSFDFIFLDSERTQYMWWLEHIKRILQPKGLLVVDNATSHA
NELAEFIKMIEEDKMFETVLLAFQNGAFVARKKQ

Specific function: 4-O-methyltransferase for the lactone ring of midecamycin and other macrolide antibiotics [H]

COG id: COG4122

COG function: function code R; Predicted O-methyltransferase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily. Type 3 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002935 [H]

Pfam domain/function: PF01596 Methyltransf_3 [H]

EC number: NA

Molecular weight: Translated: 22244; Mature: 22244

Theoretical pI: Translated: 4.66; Mature: 4.66

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDTLNSLLFQLEQYGEEHDRNKKTREEKLRNISREMGQFLSILVKGCSAKNILEIGTSNG
CCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCC
YSTLWLADAVEETNGNVTTVELSSERVGEALANFENANLLQRIDVHNQEAGAFLDSQLDH
CEEEEEHHHHHHCCCCEEEEEECHHHHHHHHHCCCCCHHHHHHCCCCCHHHHHHHHHCCC
SFDFIFLDSERTQYMWWLEHIKRILQPKGLLVVDNATSHANELAEFIKMIEEDKMFETVL
CEEEEEECCCCHHHHHHHHHHHHHHCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHH
LAFQNGAFVARKKQ
HHHCCCCEEEECCC
>Mature Secondary Structure
MDTLNSLLFQLEQYGEEHDRNKKTREEKLRNISREMGQFLSILVKGCSAKNILEIGTSNG
CCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCC
YSTLWLADAVEETNGNVTTVELSSERVGEALANFENANLLQRIDVHNQEAGAFLDSQLDH
CEEEEEHHHHHHCCCCEEEEEECHHHHHHHHHCCCCCHHHHHHCCCCCHHHHHHHHHCCC
SFDFIFLDSERTQYMWWLEHIKRILQPKGLLVVDNATSHANELAEFIKMIEEDKMFETVL
CEEEEEECCCCHHHHHHHHHHHHHHCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHH
LAFQNGAFVARKKQ
HHHCCCCEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1629172 [H]