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The map label for this gene is nsr [H]

Identifier: 218903535

GI number: 218903535

Start: 2302481

End: 2303176

Strand: Direct

Name: nsr [H]

Synonym: BCAH820_2419

Alternate gene names: 218903535

Gene position: 2302481-2303176 (Clockwise)

Preceding gene: 218903534

Following gene: 218903536

Centisome position: 43.42

GC content: 29.31

Gene sequence:

>696_bases
GTGGAGAATAGATCAGAATTAATTATGCATTATTTGAAAACTTATAAATTGCTTGAGTTTTTTTCGGAAATAGATATAGA
TTATTTGCAAGTAAATCACTTTAAAAAAGGTACACTTATTTGTGATAAAGATGAGGAAATTCATCGTTTATATTTCGTTG
TTAAAGGTAAAGTAAAAGTTTACACGATTACACCAGAAGGAAAGAAACTCATCCTTCGTTTTATTAATCCATTGGCAGTT
GTTGGCGATATTGAATTAATACAAAAAAGTAAGACGCATAATGTCGTTGAAGCTTGTTCAGATGTTATAACTATCTCCAT
TTCTAATGCTGTAATTAGAAACAAGTTAATACAGGATCCTATATTTATGAACTTCCTACTTGAAAACATTGCGAACACAT
TAAAGATATCGACTCGTTTTACAGCTCTTAATTTACTTTATCCAGTAGAAGTACGTGTAGCTAGTTATTTACTTTCTATT
TCTACTGATAGTAACGGGAATATGTATAAAGAGGATTTGGATGCAACTTCGGTATCAAGTATCGCGGATTTTATAGGAGT
AAGCTATAGACACGTAATTCGTGTGTTACAAAAATTTTATAATGAAAAATTAATTGAAAAGAGTAATGGAGTTATTATAA
TTAAAGAAATTTCTAGAATGAAGGAAGTCGCGAAAGATAATATATATGAGCAATAA

Upstream 100 bases:

>100_bases
ATAAAAAAGATACAAATGGAGAGATATCACATTGTGGGAACAATAGTAATGATTATAGGTATTGCTGTATTTAATATGTA
AATGAAAGGAGGAAATGAAA

Downstream 100 bases:

>100_bases
AAGGGAGAGAAGGATGATGAGTGGATTTAGTTTAGCTATATTAGCTGGAGTATTAATTAGCTTACAATCTGTTTTTAATA
CAAAAGTGAATGAAAATGTA

Product: catabolite gene activator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 231; Mature: 231

Protein sequence:

>231_residues
MENRSELIMHYLKTYKLLEFFSEIDIDYLQVNHFKKGTLICDKDEEIHRLYFVVKGKVKVYTITPEGKKLILRFINPLAV
VGDIELIQKSKTHNVVEACSDVITISISNAVIRNKLIQDPIFMNFLLENIANTLKISTRFTALNLLYPVEVRVASYLLSI
STDSNGNMYKEDLDATSVSSIADFIGVSYRHVIRVLQKFYNEKLIEKSNGVIIIKEISRMKEVAKDNIYEQ

Sequences:

>Translated_231_residues
MENRSELIMHYLKTYKLLEFFSEIDIDYLQVNHFKKGTLICDKDEEIHRLYFVVKGKVKVYTITPEGKKLILRFINPLAV
VGDIELIQKSKTHNVVEACSDVITISISNAVIRNKLIQDPIFMNFLLENIANTLKISTRFTALNLLYPVEVRVASYLLSI
STDSNGNMYKEDLDATSVSSIADFIGVSYRHVIRVLQKFYNEKLIEKSNGVIIIKEISRMKEVAKDNIYEQ
>Mature_231_residues
MENRSELIMHYLKTYKLLEFFSEIDIDYLQVNHFKKGTLICDKDEEIHRLYFVVKGKVKVYTITPEGKKLILRFINPLAV
VGDIELIQKSKTHNVVEACSDVITISISNAVIRNKLIQDPIFMNFLLENIANTLKISTRFTALNLLYPVEVRVASYLLSI
STDSNGNMYKEDLDATSVSSIADFIGVSYRHVIRVLQKFYNEKLIEKSNGVIIIKEISRMKEVAKDNIYEQ

Specific function: Transcription regulator involved in mid-term, stationary-phase viability under nitrogen starvation. Might control expression of the salvage pathways or in some other way repress the recycling of nucleobases to nucleic acids and enhance their use as genera

COG id: COG0664

COG function: function code T; cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH crp-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1788487, Length=210, Percent_Identity=23.3333333333333, Blast_Score=72, Evalue=2e-14,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018490
- InterPro:   IPR000595
- InterPro:   IPR012318
- InterPro:   IPR014710 [H]

Pfam domain/function: PF00027 cNMP_binding [H]

EC number: NA

Molecular weight: Translated: 26632; Mature: 26632

Theoretical pI: Translated: 8.18; Mature: 8.18

Prosite motif: PS50042 CNMP_BINDING_3 ; PS51063 HTH_CRP_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MENRSELIMHYLKTYKLLEFFSEIDIDYLQVNHFKKGTLICDKDEEIHRLYFVVKGKVKV
CCCHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCEEECCCHHHEEEEEEEECCEEE
YTITPEGKKLILRFINPLAVVGDIELIQKSKTHNVVEACSDVITISISNAVIRNKLIQDP
EEECCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHEEEEEEHHHHHHHHHHCCH
IFMNFLLENIANTLKISTRFTALNLLYPVEVRVASYLLSISTDSNGNMYKEDLDATSVSS
HHHHHHHHHHHHHHHHHHHEEEEEEEEHHHHHHHHHHHEEEECCCCCCCHHHCCHHHHHH
IADFIGVSYRHVIRVLQKFYNEKLIEKSNGVIIIKEISRMKEVAKDNIYEQ
HHHHHCCCHHHHHHHHHHHHHHHHHCCCCCEEEEHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MENRSELIMHYLKTYKLLEFFSEIDIDYLQVNHFKKGTLICDKDEEIHRLYFVVKGKVKV
CCCHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCEEECCCHHHEEEEEEEECCEEE
YTITPEGKKLILRFINPLAVVGDIELIQKSKTHNVVEACSDVITISISNAVIRNKLIQDP
EEECCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHEEEEEEHHHHHHHHHHCCH
IFMNFLLENIANTLKISTRFTALNLLYPVEVRVASYLLSISTDSNGNMYKEDLDATSVSS
HHHHHHHHHHHHHHHHHHHEEEEEEEEHHHHHHHHHHHEEEECCCCCCCHHHCCHHHHHH
IADFIGVSYRHVIRVLQKFYNEKLIEKSNGVIIIKEISRMKEVAKDNIYEQ
HHHHHCCCHHHHHHHHHHHHHHHHHCCCCCEEEEHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]