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The map label for this gene is yhdP [H]

Identifier: 218903429

GI number: 218903429

Start: 2198728

End: 2200059

Strand: Direct

Name: yhdP [H]

Synonym: BCAH820_2313

Alternate gene names: 218903429

Gene position: 2198728-2200059 (Clockwise)

Preceding gene: 218903427

Following gene: 218903430

Centisome position: 41.46

GC content: 32.36

Gene sequence:

>1332_bases
GTGATTGTTTTAATTGCCTTAACGGCATTTTTCGTTGCAGCAGAGTTTGCAATTGTTAAAGTACGAAGTTCACGAATTGA
CTATTTAATTGCAGAAGGAAATAATCGTGCAACATCTGTCAAAACAGTCATTACAAACTTAGACGAATATTTATCTGCTT
GTCAGCTAGGAATAACAGTTACAGCACTGGGAATTGGGTGGTTTGGTAAACCAGCATTAAAGCAAATGTTTGACACGCTT
TTTGTGAATTTGAACATTTCTACTCAACTGGCAGACATTTTTGCTGTAATTTTAGTGTTTTTGTTTATTACATTTTTACA
TGTTGTAATAGGGGAATTGGCCCCAAAAACATTTGCGATTCAAAAAGCTGAGCAGGTAAGTTTATTTGTTGCTAAACCGT
TAACTTTCTTTTATCGTATGGCATTTCCATTTATTTGGCTATTAAATGGATCAGCCCGAATTATTACGAAGTTGTTAGGG
CTGAAACCACCGAAAGGGCACGATGAAGTTCATTCAGAAGAAGAATTACGGTTGTTAGTTTCAGAAAGTTACAAAAATGG
AGAGATTAATCAGTCTGAATATAAATATGTAAATAAAATCTTTGAATTTGATGATCGTATAGCAAAAGAAATAATGGTAC
CCCGAACTGAAATGCATATTATAAGGAAAGAAATGCCTGCTGAAGAAGCTTTGCAAAAGATGTCTCGGGAAAAATATACA
AGATATCCAGTTGTTGATGGAGACAAAGATCACGTAATAGGCTTTGTGAACTTTAAAGATATTTTTACAGATTTTGTGCA
GCATAAAGCGGTTCGTAATAAGAAAGTAGAGCAATATATTAGGCCGATTATTTTAGTTATTGACTCTATCCCAATACACG
ACTTATTTTTAAAAATGCAAAAACAAAGAACACATATTGCTATATTGATAGATGAATATGGTGGTACGTCTGGACTTGTT
ACTGTTGAAGACATTTTAGAAGAAATAGTTGGAGATATTCAAGATGAATTTGATACAGATGAACAGCCAGAAATTCAACA
AGTTAGTGAAACGAAAACGATACTAGAGGGAAAAGTACTTGTTAGTGAAGTAAATACGTTATTAGGTTTAACAATAGATG
ATAATGGTGTTGATACAATTGGTGGATGGATTTTAACGAAAAATATAGAAATTGCTGAAGAGGATTTCATTGAAATCGAA
AATTATAAGTTTTGCGTGAAAGAATTAGATGGACACTATATAAAGAGATTAGAAGTTACAAAAACTGTAGAATCAATTGT
TATTTTAGAAGATGAAAAACAAATTTCATTACAAGAACAAATTAGTTCGTAG

Upstream 100 bases:

>100_bases
TAGAATGCTTACTTCACTTGAATAAAATTAAGTAGGAGGTGGCTTCCTTGCTTACAATGTAAGTAAGGAAAAGTATTTGG
ACATATATAGTATAAGTATA

Downstream 100 bases:

>100_bases
ACTCTGCTAGATGGCAGAGTTTTTTTTGAGCATAATGTTTTTGGCAAAATAAGGGCTATGTTACAATGGAATAAGTCAGA
CCTTTCACTAGGTGAAGTAT

Product: CBS domain protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 443; Mature: 443

Protein sequence:

>443_residues
MIVLIALTAFFVAAEFAIVKVRSSRIDYLIAEGNNRATSVKTVITNLDEYLSACQLGITVTALGIGWFGKPALKQMFDTL
FVNLNISTQLADIFAVILVFLFITFLHVVIGELAPKTFAIQKAEQVSLFVAKPLTFFYRMAFPFIWLLNGSARIITKLLG
LKPPKGHDEVHSEEELRLLVSESYKNGEINQSEYKYVNKIFEFDDRIAKEIMVPRTEMHIIRKEMPAEEALQKMSREKYT
RYPVVDGDKDHVIGFVNFKDIFTDFVQHKAVRNKKVEQYIRPIILVIDSIPIHDLFLKMQKQRTHIAILIDEYGGTSGLV
TVEDILEEIVGDIQDEFDTDEQPEIQQVSETKTILEGKVLVSEVNTLLGLTIDDNGVDTIGGWILTKNIEIAEEDFIEIE
NYKFCVKELDGHYIKRLEVTKTVESIVILEDEKQISLQEQISS

Sequences:

>Translated_443_residues
MIVLIALTAFFVAAEFAIVKVRSSRIDYLIAEGNNRATSVKTVITNLDEYLSACQLGITVTALGIGWFGKPALKQMFDTL
FVNLNISTQLADIFAVILVFLFITFLHVVIGELAPKTFAIQKAEQVSLFVAKPLTFFYRMAFPFIWLLNGSARIITKLLG
LKPPKGHDEVHSEEELRLLVSESYKNGEINQSEYKYVNKIFEFDDRIAKEIMVPRTEMHIIRKEMPAEEALQKMSREKYT
RYPVVDGDKDHVIGFVNFKDIFTDFVQHKAVRNKKVEQYIRPIILVIDSIPIHDLFLKMQKQRTHIAILIDEYGGTSGLV
TVEDILEEIVGDIQDEFDTDEQPEIQQVSETKTILEGKVLVSEVNTLLGLTIDDNGVDTIGGWILTKNIEIAEEDFIEIE
NYKFCVKELDGHYIKRLEVTKTVESIVILEDEKQISLQEQISS
>Mature_443_residues
MIVLIALTAFFVAAEFAIVKVRSSRIDYLIAEGNNRATSVKTVITNLDEYLSACQLGITVTALGIGWFGKPALKQMFDTL
FVNLNISTQLADIFAVILVFLFITFLHVVIGELAPKTFAIQKAEQVSLFVAKPLTFFYRMAFPFIWLLNGSARIITKLLG
LKPPKGHDEVHSEEELRLLVSESYKNGEINQSEYKYVNKIFEFDDRIAKEIMVPRTEMHIIRKEMPAEEALQKMSREKYT
RYPVVDGDKDHVIGFVNFKDIFTDFVQHKAVRNKKVEQYIRPIILVIDSIPIHDLFLKMQKQRTHIAILIDEYGGTSGLV
TVEDILEEIVGDIQDEFDTDEQPEIQQVSETKTILEGKVLVSEVNTLLGLTIDDNGVDTIGGWILTKNIEIAEEDFIEIE
NYKFCVKELDGHYIKRLEVTKTVESIVILEDEKQISLQEQISS

Specific function: Unknown

COG id: COG1253

COG function: function code R; Hemolysins and related proteins containing CBS domains

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 CBS domains [H]

Homologues:

Organism=Homo sapiens, GI310128564, Length=405, Percent_Identity=45.1851851851852, Blast_Score=377, Evalue=1e-104,
Organism=Escherichia coli, GI1790664, Length=425, Percent_Identity=24.4705882352941, Blast_Score=147, Evalue=2e-36,
Organism=Escherichia coli, GI145693175, Length=418, Percent_Identity=23.6842105263158, Blast_Score=121, Evalue=8e-29,
Organism=Escherichia coli, GI1786879, Length=254, Percent_Identity=30.7086614173228, Blast_Score=116, Evalue=3e-27,
Organism=Escherichia coli, GI87082033, Length=236, Percent_Identity=23.3050847457627, Blast_Score=80, Evalue=3e-16,
Organism=Escherichia coli, GI1788119, Length=237, Percent_Identity=22.7848101265823, Blast_Score=68, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016169
- InterPro:   IPR000644
- InterPro:   IPR002550
- InterPro:   IPR005170 [H]

Pfam domain/function: PF00571 CBS; PF03471 CorC_HlyC; PF01595 DUF21 [H]

EC number: NA

Molecular weight: Translated: 50489; Mature: 50489

Theoretical pI: Translated: 4.73; Mature: 4.73

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIVLIALTAFFVAAEFAIVKVRSSRIDYLIAEGNNRATSVKTVITNLDEYLSACQLGITV
CEEEHHHHHHHHHHHHHHEEEECCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHCEEE
TALGIGWFGKPALKQMFDTLFVNLNISTQLADIFAVILVFLFITFLHVVIGELAPKTFAI
EEEECCCCCCHHHHHHHHHHEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHH
QKAEQVSLFVAKPLTFFYRMAFPFIWLLNGSARIITKLLGLKPPKGHDEVHSEEELRLLV
CCHHHHHHHHHHHHHHHHHHHHHHEEEECCCHHHHHHHHCCCCCCCCCCCCCHHHHHHHH
SESYKNGEINQSEYKYVNKIFEFDDRIAKEIMVPRTEMHIIRKEMPAEEALQKMSREKYT
HCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCHHHHHHHHHHHHCC
RYPVVDGDKDHVIGFVNFKDIFTDFVQHKAVRNKKVEQYIRPIILVIDSIPIHDLFLKMQ
CCCCCCCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHH
KQRTHIAILIDEYGGTSGLVTVEDILEEIVGDIQDEFDTDEQPEIQQVSETKTILEGKVL
HCCCEEEEEEECCCCCCCCEEHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHH
VSEVNTLLGLTIDDNGVDTIGGWILTKNIEIAEEDFIEIENYKFCVKELDGHYIKRLEVT
HHHHHHHEEEEECCCCCCCCCCEEEECCCEECHHHHEECCCHHHHHHHHCCHHHHHHHHH
KTVESIVILEDEKQISLQEQISS
HHHHEEEEEECCCHHHHHHHHCC
>Mature Secondary Structure
MIVLIALTAFFVAAEFAIVKVRSSRIDYLIAEGNNRATSVKTVITNLDEYLSACQLGITV
CEEEHHHHHHHHHHHHHHEEEECCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHCEEE
TALGIGWFGKPALKQMFDTLFVNLNISTQLADIFAVILVFLFITFLHVVIGELAPKTFAI
EEEECCCCCCHHHHHHHHHHEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHH
QKAEQVSLFVAKPLTFFYRMAFPFIWLLNGSARIITKLLGLKPPKGHDEVHSEEELRLLV
CCHHHHHHHHHHHHHHHHHHHHHHEEEECCCHHHHHHHHCCCCCCCCCCCCCHHHHHHHH
SESYKNGEINQSEYKYVNKIFEFDDRIAKEIMVPRTEMHIIRKEMPAEEALQKMSREKYT
HCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCHHHHHHHHHHHHCC
RYPVVDGDKDHVIGFVNFKDIFTDFVQHKAVRNKKVEQYIRPIILVIDSIPIHDLFLKMQ
CCCCCCCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHH
KQRTHIAILIDEYGGTSGLVTVEDILEEIVGDIQDEFDTDEQPEIQQVSETKTILEGKVL
HCCCEEEEEEECCCCCCCCEEHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHH
VSEVNTLLGLTIDDNGVDTIGGWILTKNIEIAEEDFIEIENYKFCVKELDGHYIKRLEVT
HHHHHHHEEEEECCCCCCCCCCEEEECCCEECHHHHEECCCHHHHHHHHCCHHHHHHHHH
KTVESIVILEDEKQISLQEQISS
HHHHEEEEEECCCHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9579061; 9384377 [H]