Click here to switch to the map view.

The map label for this gene is flp [H]

Identifier: 218903378

GI number: 218903378

Start: 2150137

End: 2151594

Strand: Reverse

Name: flp [H]

Synonym: BCAH820_2262

Alternate gene names: 218903378

Gene position: 2151594-2150137 (Counterclockwise)

Preceding gene: 218903384

Following gene: 218903371

Centisome position: 40.58

GC content: 36.69

Gene sequence:

>1458_bases
ATGTCTAAAATTGAAACCCCTGTTATGGCTTCTTTACAAACAACGGTTGAAAAAATGATGAAGGATTTAAATGTTCCTGG
TGCTGCTGTAGCTGTTATAAAAGACGGTGAAATGATTATTTCAGAAGGTTTCGGCTATCGTAATTTAGAGACAAAAGCCC
CTGTTACACCGCGTACTTTGTTCGCAATCGGTTCCTCAACGAAAGCTTTTGGCACACTTTCATTAAGCTTATTAGCGCAG
CAAAAAAAGTTTAATTGGGATGCTCCTGTCCAGTCTTATATACAAAACTTCTCTTTATCTGAACTACTTGCTAGCTCACA
AGTTACCGGACGAGATTTAGCTTCTCATCGAACTGGCGTAAGCCGCCATGAGGCTCTTTGGTATAGCTCTTCCTTATCTC
GAAAAGATCTCGTTGAAAAAATAAAGCATTTACCACTTGATGCACCGTTTCGGACTTCATTTCTATATAACAACTTAATG
TATGCGACAATTAGCTATATTGTAGAAAACATCACAAATCAAACGTGGGAGCAATACGCTACAGAACATATTTTAGAACC
TTTAAATATGAGACATACAAACTTCTCTGTTACCGATTCACAAACGACAGAAGACTATGCTTTACCTTACATTGAAAATG
ATGGTGAAATAAAAGAAGTTCCATTCCGCAACATCGATACAGTCGGCGCTGCTGGATGTATTAATTCTACAATTGAAGAT
ATGGCAAATTGGGTACTTCTTCACTTAAACAATGGAAAATTTGGAGATCATGAATTAATCTCCTCTGAATTATTACAACA
AATGTATACACCACACAATTCAATTCCAGATCAACCAGTTTTATCACTTCCTGAATCTCCATTAAATAGTTACGGCCTTG
GTTGGTTTATAAGCGCTTATCGTGGTAATAAGGTGATTCATCATGGTGGTAATATTGATGGATTTTCAGCGCTTGTTTCT
TTCATACCAAAAGAAAACATCGGCCTTGTCATTTTAACGAATGCTGGAGGCACATTACTGCCTACTTATCTTGCTAATCA
AATTTATGACGAACTGCTTGAATTAGAAACCATTGATTGGCATAAACGTGCTGTAGAAGATACGGAAAAAATGAAGGAAA
TGATGAAAGAAGCAACCGAATCCGTTCCAGAACAAATTAAAGGGACTACACCTTCTCACAAATTAGAGGATTACACTGGT
ACTTTCGAACATCCTGCATACGGAACATTACAAGTACACAAACAAGATGATTCGTTATTTGTACAATTTATGGAGATGGA
CATTCAATTGGGCCATCATCATTACGACATCTTCTCTGCAAAAGTTGACTTATTCCAAATGAAGATGAATCTATTATTTG
CATATGAAATGAATGTGAACGGTGAATTTCCATCCCTTCAGTTACATGTACCAGCTATGTTAAGTACTCAGCCGCTTGCA
TTTAAGAAAATTAAATAA

Upstream 100 bases:

>100_bases
CTTACAAAATTATTAACTTTCCATATTTAAAAAGGTTTTCATTTTCTATTACCGAAAGTATAGTGCGGTAGAACAAAAAT
TATATTTGGAGGTTATAAGT

Downstream 100 bases:

>100_bases
AGTTTTAATAGAGGGATGATAACACGTCCCTCTATTTTTCATTACAATCCCCATCCAAATAAAGGATTTTAAGCATTGAA
TAAAGAATCCCTTTATTTAA

Product: hypothetical protein

Products: A Substituted Beta- Amino Acid. [C]

Alternate protein names: FmtA-like protein [H]

Number of amino acids: Translated: 485; Mature: 484

Protein sequence:

>485_residues
MSKIETPVMASLQTTVEKMMKDLNVPGAAVAVIKDGEMIISEGFGYRNLETKAPVTPRTLFAIGSSTKAFGTLSLSLLAQ
QKKFNWDAPVQSYIQNFSLSELLASSQVTGRDLASHRTGVSRHEALWYSSSLSRKDLVEKIKHLPLDAPFRTSFLYNNLM
YATISYIVENITNQTWEQYATEHILEPLNMRHTNFSVTDSQTTEDYALPYIENDGEIKEVPFRNIDTVGAAGCINSTIED
MANWVLLHLNNGKFGDHELISSELLQQMYTPHNSIPDQPVLSLPESPLNSYGLGWFISAYRGNKVIHHGGNIDGFSALVS
FIPKENIGLVILTNAGGTLLPTYLANQIYDELLELETIDWHKRAVEDTEKMKEMMKEATESVPEQIKGTTPSHKLEDYTG
TFEHPAYGTLQVHKQDDSLFVQFMEMDIQLGHHHYDIFSAKVDLFQMKMNLLFAYEMNVNGEFPSLQLHVPAMLSTQPLA
FKKIK

Sequences:

>Translated_485_residues
MSKIETPVMASLQTTVEKMMKDLNVPGAAVAVIKDGEMIISEGFGYRNLETKAPVTPRTLFAIGSSTKAFGTLSLSLLAQ
QKKFNWDAPVQSYIQNFSLSELLASSQVTGRDLASHRTGVSRHEALWYSSSLSRKDLVEKIKHLPLDAPFRTSFLYNNLM
YATISYIVENITNQTWEQYATEHILEPLNMRHTNFSVTDSQTTEDYALPYIENDGEIKEVPFRNIDTVGAAGCINSTIED
MANWVLLHLNNGKFGDHELISSELLQQMYTPHNSIPDQPVLSLPESPLNSYGLGWFISAYRGNKVIHHGGNIDGFSALVS
FIPKENIGLVILTNAGGTLLPTYLANQIYDELLELETIDWHKRAVEDTEKMKEMMKEATESVPEQIKGTTPSHKLEDYTG
TFEHPAYGTLQVHKQDDSLFVQFMEMDIQLGHHHYDIFSAKVDLFQMKMNLLFAYEMNVNGEFPSLQLHVPAMLSTQPLA
FKKIK
>Mature_484_residues
SKIETPVMASLQTTVEKMMKDLNVPGAAVAVIKDGEMIISEGFGYRNLETKAPVTPRTLFAIGSSTKAFGTLSLSLLAQQ
KKFNWDAPVQSYIQNFSLSELLASSQVTGRDLASHRTGVSRHEALWYSSSLSRKDLVEKIKHLPLDAPFRTSFLYNNLMY
ATISYIVENITNQTWEQYATEHILEPLNMRHTNFSVTDSQTTEDYALPYIENDGEIKEVPFRNIDTVGAAGCINSTIEDM
ANWVLLHLNNGKFGDHELISSELLQQMYTPHNSIPDQPVLSLPESPLNSYGLGWFISAYRGNKVIHHGGNIDGFSALVSF
IPKENIGLVILTNAGGTLLPTYLANQIYDELLELETIDWHKRAVEDTEKMKEMMKEATESVPEQIKGTTPSHKLEDYTGT
FEHPAYGTLQVHKQDDSLFVQFMEMDIQLGHHHYDIFSAKVDLFQMKMNLLFAYEMNVNGEFPSLQLHVPAMLSTQPLAF
KKIK

Specific function: Its precise function is unknown. Has no penicillin- binding activity and is not involved in methicillin resistance [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI239747261, Length=381, Percent_Identity=24.1469816272966, Blast_Score=76, Evalue=7e-14,
Organism=Homo sapiens, GI239752721, Length=381, Percent_Identity=24.1469816272966, Blast_Score=76, Evalue=7e-14,
Organism=Homo sapiens, GI239741085, Length=381, Percent_Identity=24.1469816272966, Blast_Score=76, Evalue=7e-14,
Organism=Homo sapiens, GI26051231, Length=125, Percent_Identity=30.4, Blast_Score=69, Evalue=1e-11,
Organism=Homo sapiens, GI26051233, Length=125, Percent_Identity=30.4, Blast_Score=68, Evalue=2e-11,
Organism=Escherichia coli, GI87082101, Length=314, Percent_Identity=23.5668789808917, Blast_Score=67, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17550934, Length=329, Percent_Identity=24.6200607902736, Blast_Score=90, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI115533026, Length=358, Percent_Identity=24.8603351955307, Blast_Score=67, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012338
- InterPro:   IPR001466 [H]

Pfam domain/function: PF00144 Beta-lactamase [H]

EC number: 3.5.2.6 [C]

Molecular weight: Translated: 54609; Mature: 54478

Theoretical pI: Translated: 5.29; Mature: 5.29

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKIETPVMASLQTTVEKMMKDLNVPGAAVAVIKDGEMIISEGFGYRNLETKAPVTPRTL
CCCCCCHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCEEEECCCCCCCCCCCCCCCCCEE
FAIGSSTKAFGTLSLSLLAQQKKFNWDAPVQSYIQNFSLSELLASSQVTGRDLASHRTGV
EEECCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHCCCHHHHHHHCCCCHHHHHHHHCCC
SRHEALWYSSSLSRKDLVEKIKHLPLDAPFRTSFLYNNLMYATISYIVENITNQTWEQYA
CHHHHHEECCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TEHILEPLNMRHTNFSVTDSQTTEDYALPYIENDGEIKEVPFRNIDTVGAAGCINSTIED
HHHHHCCCCCCCCCEEECCCCCCCCCCCCEECCCCCEEECCCCCCCCCCCHHHHHHHHHH
MANWVLLHLNNGKFGDHELISSELLQQMYTPHNSIPDQPVLSLPESPLNSYGLGWFISAY
HHCEEEEEECCCCCCCHHHHHHHHHHHHCCCCCCCCCCCHHCCCCCCCCCCCCHHEEEEE
RGNKVIHHGGNIDGFSALVSFIPKENIGLVILTNAGGTLLPTYLANQIYDELLELETIDW
CCCEEEECCCCCCHHHHHHHHCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHCCCHH
HKRAVEDTEKMKEMMKEATESVPEQIKGTTPSHKLEDYTGTFEHPAYGTLQVHKQDDSLF
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCEEEEEECCHHHH
VQFMEMDIQLGHHHYDIFSAKVDLFQMKMNLLFAYEMNVNGEFPSLQLHVPAMLSTQPLA
HHHHHHHHHHCCEEEEHHHHHHHHHHHHEEEEEEEEECCCCCCCCEEEECCHHHCCCCCH
FKKIK
HCCCC
>Mature Secondary Structure 
SKIETPVMASLQTTVEKMMKDLNVPGAAVAVIKDGEMIISEGFGYRNLETKAPVTPRTL
CCCCCHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCEEEECCCCCCCCCCCCCCCCCEE
FAIGSSTKAFGTLSLSLLAQQKKFNWDAPVQSYIQNFSLSELLASSQVTGRDLASHRTGV
EEECCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHCCCHHHHHHHCCCCHHHHHHHHCCC
SRHEALWYSSSLSRKDLVEKIKHLPLDAPFRTSFLYNNLMYATISYIVENITNQTWEQYA
CHHHHHEECCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TEHILEPLNMRHTNFSVTDSQTTEDYALPYIENDGEIKEVPFRNIDTVGAAGCINSTIED
HHHHHCCCCCCCCCEEECCCCCCCCCCCCEECCCCCEEECCCCCCCCCCCHHHHHHHHHH
MANWVLLHLNNGKFGDHELISSELLQQMYTPHNSIPDQPVLSLPESPLNSYGLGWFISAY
HHCEEEEEECCCCCCCHHHHHHHHHHHHCCCCCCCCCCCHHCCCCCCCCCCCCHHEEEEE
RGNKVIHHGGNIDGFSALVSFIPKENIGLVILTNAGGTLLPTYLANQIYDELLELETIDW
CCCEEEECCCCCCHHHHHHHHCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHCCCHH
HKRAVEDTEKMKEMMKEATESVPEQIKGTTPSHKLEDYTGTFEHPAYGTLQVHKQDDSLF
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCEEEEEECCHHHH
VQFMEMDIQLGHHHYDIFSAKVDLFQMKMNLLFAYEMNVNGEFPSLQLHVPAMLSTQPLA
HHHHHHHHHHCCEEEEHHHHHHHHHHHHEEEEEEEEECCCCCCCCEEEECCHHHCCCCCH
FKKIK
HCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: A Beta-Lactam; H2O [C]

Specific reaction: A Beta-Lactam + H2O = A Substituted Beta- Amino Acid. [C]

General reaction: Carboxylic acid amide hydrolysis [C]

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA