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The map label for this gene is moaE1 [H]

Identifier: 218903285

GI number: 218903285

Start: 2055325

End: 2055795

Strand: Direct

Name: moaE1 [H]

Synonym: BCAH820_2169

Alternate gene names: 218903285

Gene position: 2055325-2055795 (Clockwise)

Preceding gene: 218903284

Following gene: 218903286

Centisome position: 38.76

GC content: 40.13

Gene sequence:

>471_bases
ATGACACATACGTATTATGAAGTAATTGATACACCTATATCAATTGAAGAAGTTACAAACAAAGTAATTCGGCGTGAGTG
TGGTGCGGTTACTACTTTTATTGGCACTGTTAGAGAATTTACGAAAGGCCGACGTACGCTTTATTTAGAGTATGTAGCTT
ATAAGACGATGGCGGAGAAACAGCTTGAGAGAATTGGTACCGAAGTAGGGGAGAAATGGCCTGGAACATATGTGGCAATT
ACACATCGCATTGGTACGTTACAAATTTCGGATCTTGCTGTTGTTGTCGCTGTTGCTACACCACATCGGAAAGCGGCCTA
TGAAGCAAATGAATATATTATGGAGCGTATAAAACAAATTGTTCCAATTTGGAAGAAAGAGTTTTGGGAAGATGGTGAGT
CATGGATAGGTGATCAGTTAGAGCGGGTAACATATGCAAATGGTGAGCCTAGAAAGGAGATGAGAATATGA

Upstream 100 bases:

>100_bases
AATCAACCAGCGGAAGTGAATGGCCATGGAAAGAATCGCTTCGTTCATACAAATAATAGAAAAATAGGTTGCTAATTTAT
ACAAAGATAAGAGGTGCGAA

Downstream 100 bases:

>100_bases
TTAAAGTGCTATTATTTGCACATTTACAGGAAGAAGTAAGGAAGTCGTCCTTGCACATAGATTGTGAAAATATTACAGTC
GCGAAGCTGAAGGAAGTTCT

Product: molybdopterin converting factor, subunit 2

Products: NA

Alternate protein names: MPT synthase subunit 2; Molybdenum cofactor biosynthesis protein E; Molybdopterin-converting factor large subunit; Molybdopterin-converting factor subunit 2 [H]

Number of amino acids: Translated: 156; Mature: 155

Protein sequence:

>156_residues
MTHTYYEVIDTPISIEEVTNKVIRRECGAVTTFIGTVREFTKGRRTLYLEYVAYKTMAEKQLERIGTEVGEKWPGTYVAI
THRIGTLQISDLAVVVAVATPHRKAAYEANEYIMERIKQIVPIWKKEFWEDGESWIGDQLERVTYANGEPRKEMRI

Sequences:

>Translated_156_residues
MTHTYYEVIDTPISIEEVTNKVIRRECGAVTTFIGTVREFTKGRRTLYLEYVAYKTMAEKQLERIGTEVGEKWPGTYVAI
THRIGTLQISDLAVVVAVATPHRKAAYEANEYIMERIKQIVPIWKKEFWEDGESWIGDQLERVTYANGEPRKEMRI
>Mature_155_residues
THTYYEVIDTPISIEEVTNKVIRRECGAVTTFIGTVREFTKGRRTLYLEYVAYKTMAEKQLERIGTEVGEKWPGTYVAIT
HRIGTLQISDLAVVVAVATPHRKAAYEANEYIMERIKQIVPIWKKEFWEDGESWIGDQLERVTYANGEPRKEMRI

Specific function: Converts molybdopterin precursor Z into molybdopterin. This requires the incorporation of two sulfur atoms into precursor Z to generate a dithiolene group. The sulfur is provided by moaD [H]

COG id: COG0314

COG function: function code H; Molybdopterin converting factor, large subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the moaE family [H]

Homologues:

Organism=Homo sapiens, GI4758732, Length=127, Percent_Identity=38.5826771653543, Blast_Score=120, Evalue=4e-28,
Organism=Escherichia coli, GI1787003, Length=137, Percent_Identity=37.956204379562, Blast_Score=85, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI17509279, Length=130, Percent_Identity=33.0769230769231, Blast_Score=84, Evalue=2e-17,
Organism=Drosophila melanogaster, GI21356259, Length=131, Percent_Identity=34.3511450381679, Blast_Score=102, Evalue=1e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003448 [H]

Pfam domain/function: PF02391 MoaE [H]

EC number: NA

Molecular weight: Translated: 18118; Mature: 17987

Theoretical pI: Translated: 6.81; Mature: 6.81

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTHTYYEVIDTPISIEEVTNKVIRRECGAVTTFIGTVREFTKGRRTLYLEYVAYKTMAEK
CCCCHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEHHHHHHHHHHHH
QLERIGTEVGEKWPGTYVAITHRIGTLQISDLAVVVAVATPHRKAAYEANEYIMERIKQI
HHHHHHHHHHCCCCCCEEEEEECCCEEEEHHHEEEEEECCCCHHHHHHHHHHHHHHHHHH
VPIWKKEFWEDGESWIGDQLERVTYANGEPRKEMRI
HHHHHHHHHCCHHHHHHHHHHHHHCCCCCCHHCCCC
>Mature Secondary Structure 
THTYYEVIDTPISIEEVTNKVIRRECGAVTTFIGTVREFTKGRRTLYLEYVAYKTMAEK
CCCHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEHHHHHHHHHHHH
QLERIGTEVGEKWPGTYVAITHRIGTLQISDLAVVVAVATPHRKAAYEANEYIMERIKQI
HHHHHHHHHHCCCCCCEEEEEECCCEEEEHHHEEEEEECCCCHHHHHHHHHHHHHHHHHH
VPIWKKEFWEDGESWIGDQLERVTYANGEPRKEMRI
HHHHHHHHHCCHHHHHHHHHHHHHCCCCCCHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]