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The map label for this gene is bsaA [H]

Identifier: 218903270

GI number: 218903270

Start: 2036499

End: 2036981

Strand: Direct

Name: bsaA [H]

Synonym: BCAH820_2154

Alternate gene names: 218903270

Gene position: 2036499-2036981 (Clockwise)

Preceding gene: 218903265

Following gene: 218903274

Centisome position: 38.41

GC content: 35.61

Gene sequence:

>483_bases
ATGACAGTGTATGATTTTTCAGCTAAAACAATAATAGGTGAAGAAAAATCGTTAAAAGATTACGAGGGAAAAGTACTTCT
TATTGTAAATGTAGCTAGTAAATGCGGGTTTACACCGCAATATAAAGGATTACAAGAAGTATATGATAAATATAAAGAAC
AAGGGCTAGAAATACTCGGTTTCCCATGTAACCAATTCGGAGGACAAGAACCAGGTACAGAAGTAGATATTACAAGCTTT
TGTGAATTAAACTACGGTGTAAACTTCCCAATGTTTGCAAAAATTGATGTAAAAGGTGATAAGGCTCATCCTCTGTATAC
ATACATGACAGAACAAGCACCAGGTTTACTCGGTATGAAAGCAGTAAAATGGAACTTTACAAAATTTCTAATTGGAAAAG
ACGGAAAAGTAGTAGGACGTTTTGCACCGCAAACGAAGCCGGTGGATTTAGAGGTTGAGATTGAGAAGGTACTTGGTGAA
TAA

Upstream 100 bases:

>100_bases
CGTTTACAATCGTGGGGAGAAAATACGTAATAAGAGCTGTAAATTCACGAATGTAGTATAGTATAAACATAGAATGATAG
TGAAGAGAGGGGCAAAGACA

Downstream 100 bases:

>100_bases
CTAGGAGTTTCACTTTATTAAAAAATGTCTCAAAGAACTATTTTGTTCTTTGAGGCATTTTATTTACATTCACATTGTCA
ATATTAAATCGCTGAATGGA

Product: glutathione peroxidase

Products: glutathione disulfide; H2O

Alternate protein names: NA

Number of amino acids: Translated: 160; Mature: 159

Protein sequence:

>160_residues
MTVYDFSAKTIIGEEKSLKDYEGKVLLIVNVASKCGFTPQYKGLQEVYDKYKEQGLEILGFPCNQFGGQEPGTEVDITSF
CELNYGVNFPMFAKIDVKGDKAHPLYTYMTEQAPGLLGMKAVKWNFTKFLIGKDGKVVGRFAPQTKPVDLEVEIEKVLGE

Sequences:

>Translated_160_residues
MTVYDFSAKTIIGEEKSLKDYEGKVLLIVNVASKCGFTPQYKGLQEVYDKYKEQGLEILGFPCNQFGGQEPGTEVDITSF
CELNYGVNFPMFAKIDVKGDKAHPLYTYMTEQAPGLLGMKAVKWNFTKFLIGKDGKVVGRFAPQTKPVDLEVEIEKVLGE
>Mature_159_residues
TVYDFSAKTIIGEEKSLKDYEGKVLLIVNVASKCGFTPQYKGLQEVYDKYKEQGLEILGFPCNQFGGQEPGTEVDITSFC
ELNYGVNFPMFAKIDVKGDKAHPLYTYMTEQAPGLLGMKAVKWNFTKFLIGKDGKVVGRFAPQTKPVDLEVEIEKVLGE

Specific function: Not Essential For B12 Transport; However, It Is An Auxiliary Component Of The Transport System. [C]

COG id: COG0386

COG function: function code O; Glutathione peroxidase

Gene ontology:

Cell location: Periplasmic Protein [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glutathione peroxidase family [H]

Homologues:

Organism=Homo sapiens, GI75709200, Length=156, Percent_Identity=47.4358974358974, Blast_Score=135, Evalue=1e-32,
Organism=Homo sapiens, GI90903240, Length=156, Percent_Identity=47.4358974358974, Blast_Score=135, Evalue=2e-32,
Organism=Homo sapiens, GI15618997, Length=141, Percent_Identity=48.2269503546099, Blast_Score=131, Evalue=2e-31,
Organism=Homo sapiens, GI90903238, Length=131, Percent_Identity=48.8549618320611, Blast_Score=116, Evalue=9e-27,
Organism=Homo sapiens, GI192455698, Length=150, Percent_Identity=37.3333333333333, Blast_Score=111, Evalue=2e-25,
Organism=Homo sapiens, GI6006001, Length=173, Percent_Identity=38.150289017341, Blast_Score=103, Evalue=8e-23,
Organism=Homo sapiens, GI41406084, Length=184, Percent_Identity=35.3260869565217, Blast_Score=102, Evalue=1e-22,
Organism=Homo sapiens, GI4557629, Length=173, Percent_Identity=34.6820809248555, Blast_Score=98, Evalue=3e-21,
Organism=Homo sapiens, GI33186887, Length=179, Percent_Identity=34.6368715083799, Blast_Score=92, Evalue=1e-19,
Organism=Homo sapiens, GI32967607, Length=181, Percent_Identity=29.2817679558011, Blast_Score=83, Evalue=8e-17,
Organism=Escherichia coli, GI1788003, Length=160, Percent_Identity=43.75, Blast_Score=146, Evalue=6e-37,
Organism=Caenorhabditis elegans, GI17506887, Length=160, Percent_Identity=51.25, Blast_Score=172, Evalue=5e-44,
Organism=Caenorhabditis elegans, GI17535473, Length=158, Percent_Identity=48.7341772151899, Blast_Score=162, Evalue=5e-41,
Organism=Caenorhabditis elegans, GI193210707, Length=164, Percent_Identity=45.1219512195122, Blast_Score=139, Evalue=7e-34,
Organism=Caenorhabditis elegans, GI71993584, Length=159, Percent_Identity=41.5094339622642, Blast_Score=135, Evalue=9e-33,
Organism=Caenorhabditis elegans, GI193209493, Length=163, Percent_Identity=33.7423312883436, Blast_Score=107, Evalue=2e-24,
Organism=Caenorhabditis elegans, GI17550320, Length=163, Percent_Identity=34.9693251533742, Blast_Score=107, Evalue=2e-24,
Organism=Caenorhabditis elegans, GI71999642, Length=71, Percent_Identity=49.2957746478873, Blast_Score=79, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI71993573, Length=95, Percent_Identity=42.1052631578947, Blast_Score=79, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI193210709, Length=72, Percent_Identity=51.3888888888889, Blast_Score=75, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17507603, Length=106, Percent_Identity=35.8490566037736, Blast_Score=64, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI6319721, Length=159, Percent_Identity=55.9748427672956, Blast_Score=189, Evalue=2e-49,
Organism=Saccharomyces cerevisiae, GI6322228, Length=139, Percent_Identity=56.1151079136691, Blast_Score=173, Evalue=1e-44,
Organism=Saccharomyces cerevisiae, GI6322826, Length=157, Percent_Identity=45.2229299363057, Blast_Score=146, Evalue=2e-36,
Organism=Drosophila melanogaster, GI24656772, Length=160, Percent_Identity=46.25, Blast_Score=143, Evalue=5e-35,
Organism=Drosophila melanogaster, GI24656767, Length=160, Percent_Identity=46.25, Blast_Score=142, Evalue=1e-34,
Organism=Drosophila melanogaster, GI24656777, Length=160, Percent_Identity=46.25, Blast_Score=142, Evalue=1e-34,
Organism=Drosophila melanogaster, GI85726443, Length=162, Percent_Identity=40.7407407407407, Blast_Score=125, Evalue=1e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000889
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF00255 GSHPx [H]

EC number: 1.11.1.9

Molecular weight: Translated: 17879; Mature: 17748

Theoretical pI: Translated: 5.04; Mature: 5.04

Prosite motif: PS00460 GLUTATHIONE_PEROXID_1 ; PS00763 GLUTATHIONE_PEROXID_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTVYDFSAKTIIGEEKSLKDYEGKVLLIVNVASKCGFTPQYKGLQEVYDKYKEQGLEILG
CEEECCCCEEEECCCCCCCCCCCCEEEEEEEHHHCCCCCCCCCHHHHHHHHHHCCCEEEE
FPCNQFGGQEPGTEVDITSFCELNYGVNFPMFAKIDVKGDKAHPLYTYMTEQAPGLLGMK
CCCHHCCCCCCCCEECEEEEEEECCCCCCCEEEEEEECCCCCCCEEEEECCCCCCCCCEE
AVKWNFTKFLIGKDGKVVGRFAPQTKPVDLEVEIEKVLGE
EEEEEEEEEEECCCCCEEEEECCCCCCCEEEEEHHHHHCC
>Mature Secondary Structure 
TVYDFSAKTIIGEEKSLKDYEGKVLLIVNVASKCGFTPQYKGLQEVYDKYKEQGLEILG
EEECCCCEEEECCCCCCCCCCCCEEEEEEEHHHCCCCCCCCCHHHHHHHHHHCCCEEEE
FPCNQFGGQEPGTEVDITSFCELNYGVNFPMFAKIDVKGDKAHPLYTYMTEQAPGLLGMK
CCCHHCCCCCCCCEECEEEEEEECCCCCCCEEEEEEECCCCCCCEEEEECCCCCCCCCEE
AVKWNFTKFLIGKDGKVVGRFAPQTKPVDLEVEIEKVLGE
EEEEEEEEEEECCCCCEEEEECCCCCCCEEEEEHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: glutathione; H2O2

Specific reaction: 2 glutathione + H2O2 = glutathione disulfide + 2 H2O

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]