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The map label for this gene is ubiB [H]

Identifier: 218903266

GI number: 218903266

Start: 2032419

End: 2034365

Strand: Reverse

Name: ubiB [H]

Synonym: BCAH820_2150

Alternate gene names: 218903266

Gene position: 2034365-2032419 (Counterclockwise)

Preceding gene: 218903267

Following gene: 218903263

Centisome position: 38.36

GC content: 35.23

Gene sequence:

>1947_bases
ATGTTTTTTCAATTTTTTCTACTAGCAGTCATTATGTCTTTTATTAGTGGTCGACTAATTGGTACAAAACTAAATTTTTT
CAAACAAGCAAGTGCAGCCACTTTAGGTGTTTCACTTACGTCGGCTATGTATTGGTTTTTATATTTACGCTATCAAGATG
AATCGATTGTCGGTGTTGATAGATATTTTTGGCTGGGGAGCTCATTAATTGTATCGATGCTTTGTTACCTAGTTTTTGAA
TTATTTGATCCTATTAAGCGTAGCGAAATGGATGACGTAGTAATAGAAAGCAGAAACCCTATTTCAAAATTCTTCGCTAA
AATTGGTAGACAAAAAAGATATATGCGCGTCTCTTCTATTGCAATCAAACACGGAATGGGAAAATATTTAGCTTTAAAGC
GCTCACCAGAAGCAGATCGCAAGCTCGCCACTTCCCTTCGAAATACACTAGAAGAATGTGGTGGTGTATTTATTAAATTC
GGACAAGTTTTATCAACTCGATCTGATTTACTACCACCAGTTTTTATTCACGAATTATCAAACCTTCAAGAAAATGTAAC
ACGTTTATCACAACAACAAGTTGAAGAAATATTGAACAAGGAACTACATATACCGAAAGATGAAATTTTCAGCTCCTTTG
AAATGGAACCGTTAGCTGCCGCCTCTATTGGCCAAGTACATAAAGCGAAGCTCAAAGAAAACGACCAGGATGTCGTCGTT
AAACTACTACGTCCTAATATTTCTGAGACAATTAAACGTGACTTAGATATTTTAATTCACTTCGCTCTATGGATTTCCAA
CAAATCAACTTGGGCTAAAAATATCGGATTTCTTGATTTAGCACAGGGCTTCTCTACCGCAATGAAAGAAGAAATTGATT
TCAAAATCGAGGCTCGTAACTTCGAACAAGTGTCTGATTCACTAAAAAATAGTGAAACGAAAGTAAAAATACCGGAAGTA
TATCAAGAATACAGTAATTCAAAAATACTTGTGCTTGAATTTTTAGATGGAGTAAGTGTTAAAAGTGGGGCAGCATTATT
AAATGAATTACAAATTGATACGAAAAAAGTACAACGACAACTCTTTGATTGTATTTTAGAGCAAATTTTCTTTAAAGGTA
TTTTCCATGCAGACCCTCATCCAGGTAATGTGTATATTCTTCGTGATGGTACTCCTGCATTACTTGATTTCGGTTCTGTC
GGACGATTAGGAACACTTCAACAAGAGGCATTCAAGCGACTGCTTATCGGCTTTGAGCGCAAAAATTCATATGTCTTACT
TGATGGACTGCTTCAATTAGTTGAAAAGAAACCAAATGTTGATAAAGAAGGATTAGAACAGTCTATTAGTCAATTATTAA
TCCAAAGTACGTACGTTTCTACAAATAGTTCTGAAGAATTCATTCAAGGGTTGTTTCAAATAATCGCTGAATTTGAATTA
GCATTTTATCCAATGGTTGCAGGGGCTTTCCGCTCTTTAATTACGCTAGAAGGAACGATGCTACAACTAAACCCTGAATT
CAATTTAATGGATGAAGCGAAGCGCTTTGCGAAAGATCATGTAGCTAGTTTTATGCCAGTTAACAATTATTCAAGTTTAA
AAGAAGCTGCAACAAACGAATTACTCTCTATGTTACCTGCCATGCGACGCATTCCTAGAAAATTAGATGATTTAAGTTCA
AAACTAGAAAACGGAGAATTATCCGTAAAGGTCGGCTTTTTCTCTGACGAAACAAATGCATCATTCATTACTACGTTCAT
CTCACAATTCCTCATTGCATTTATTGGAACTGCATTTGGCGGAATTTCGGTAGGTGTATTGCATTTAGCAAACAATGCGA
AAGAACCAAATGATCAATTTTTAAGTGTCGTTGGTTACGGTGGTTTATTTATAAGTGCGATATTACTTGTAAGAGTAGCT
ATTCATGCGGTAAGAAAATTTAAGTAA

Upstream 100 bases:

>100_bases
TTGATCGTGCAAGTCAGGGATGTACTTCCTTGGCTTGTTGTTACAATAATTATATTCCAGTATAATACAGTAATCGAATA
AAATTCAGAGGAATGATACA

Downstream 100 bases:

>100_bases
TAATAAAACGAGTATGAAATCACTTAGATTTTATACTCGTTTTTTATTGTTTATATATTCAATATGCACTAGGAAATTTA
TGTTAAACTAAAGAAAATCG

Product: ABC1 family protein

Products: 2-octaprenyl-6-hydroxyphenol [C]

Alternate protein names: NA

Number of amino acids: Translated: 648; Mature: 648

Protein sequence:

>648_residues
MFFQFFLLAVIMSFISGRLIGTKLNFFKQASAATLGVSLTSAMYWFLYLRYQDESIVGVDRYFWLGSSLIVSMLCYLVFE
LFDPIKRSEMDDVVIESRNPISKFFAKIGRQKRYMRVSSIAIKHGMGKYLALKRSPEADRKLATSLRNTLEECGGVFIKF
GQVLSTRSDLLPPVFIHELSNLQENVTRLSQQQVEEILNKELHIPKDEIFSSFEMEPLAAASIGQVHKAKLKENDQDVVV
KLLRPNISETIKRDLDILIHFALWISNKSTWAKNIGFLDLAQGFSTAMKEEIDFKIEARNFEQVSDSLKNSETKVKIPEV
YQEYSNSKILVLEFLDGVSVKSGAALLNELQIDTKKVQRQLFDCILEQIFFKGIFHADPHPGNVYILRDGTPALLDFGSV
GRLGTLQQEAFKRLLIGFERKNSYVLLDGLLQLVEKKPNVDKEGLEQSISQLLIQSTYVSTNSSEEFIQGLFQIIAEFEL
AFYPMVAGAFRSLITLEGTMLQLNPEFNLMDEAKRFAKDHVASFMPVNNYSSLKEAATNELLSMLPAMRRIPRKLDDLSS
KLENGELSVKVGFFSDETNASFITTFISQFLIAFIGTAFGGISVGVLHLANNAKEPNDQFLSVVGYGGLFISAILLVRVA
IHAVRKFK

Sequences:

>Translated_648_residues
MFFQFFLLAVIMSFISGRLIGTKLNFFKQASAATLGVSLTSAMYWFLYLRYQDESIVGVDRYFWLGSSLIVSMLCYLVFE
LFDPIKRSEMDDVVIESRNPISKFFAKIGRQKRYMRVSSIAIKHGMGKYLALKRSPEADRKLATSLRNTLEECGGVFIKF
GQVLSTRSDLLPPVFIHELSNLQENVTRLSQQQVEEILNKELHIPKDEIFSSFEMEPLAAASIGQVHKAKLKENDQDVVV
KLLRPNISETIKRDLDILIHFALWISNKSTWAKNIGFLDLAQGFSTAMKEEIDFKIEARNFEQVSDSLKNSETKVKIPEV
YQEYSNSKILVLEFLDGVSVKSGAALLNELQIDTKKVQRQLFDCILEQIFFKGIFHADPHPGNVYILRDGTPALLDFGSV
GRLGTLQQEAFKRLLIGFERKNSYVLLDGLLQLVEKKPNVDKEGLEQSISQLLIQSTYVSTNSSEEFIQGLFQIIAEFEL
AFYPMVAGAFRSLITLEGTMLQLNPEFNLMDEAKRFAKDHVASFMPVNNYSSLKEAATNELLSMLPAMRRIPRKLDDLSS
KLENGELSVKVGFFSDETNASFITTFISQFLIAFIGTAFGGISVGVLHLANNAKEPNDQFLSVVGYGGLFISAILLVRVA
IHAVRKFK
>Mature_648_residues
MFFQFFLLAVIMSFISGRLIGTKLNFFKQASAATLGVSLTSAMYWFLYLRYQDESIVGVDRYFWLGSSLIVSMLCYLVFE
LFDPIKRSEMDDVVIESRNPISKFFAKIGRQKRYMRVSSIAIKHGMGKYLALKRSPEADRKLATSLRNTLEECGGVFIKF
GQVLSTRSDLLPPVFIHELSNLQENVTRLSQQQVEEILNKELHIPKDEIFSSFEMEPLAAASIGQVHKAKLKENDQDVVV
KLLRPNISETIKRDLDILIHFALWISNKSTWAKNIGFLDLAQGFSTAMKEEIDFKIEARNFEQVSDSLKNSETKVKIPEV
YQEYSNSKILVLEFLDGVSVKSGAALLNELQIDTKKVQRQLFDCILEQIFFKGIFHADPHPGNVYILRDGTPALLDFGSV
GRLGTLQQEAFKRLLIGFERKNSYVLLDGLLQLVEKKPNVDKEGLEQSISQLLIQSTYVSTNSSEEFIQGLFQIIAEFEL
AFYPMVAGAFRSLITLEGTMLQLNPEFNLMDEAKRFAKDHVASFMPVNNYSSLKEAATNELLSMLPAMRRIPRKLDDLSS
KLENGELSVKVGFFSDETNASFITTFISQFLIAFIGTAFGGISVGVLHLANNAKEPNDQFLSVVGYGGLFISAILLVRVA
IHAVRKFK

Specific function: Required, probably indirectly, for the hydroxylation of 2-octaprenylphenol to 2-octaprenyl-6-hydroxy-phenol, the fourth step in ubiquinone biosynthesis [H]

COG id: COG0661

COG function: function code R; Predicted unusual protein kinase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ABC1 family. UbiB subfamily [H]

Homologues:

Organism=Homo sapiens, GI41393593, Length=265, Percent_Identity=29.4339622641509, Blast_Score=117, Evalue=4e-26,
Organism=Homo sapiens, GI40254938, Length=286, Percent_Identity=30.7692307692308, Blast_Score=115, Evalue=1e-25,
Organism=Homo sapiens, GI217035081, Length=196, Percent_Identity=33.1632653061224, Blast_Score=92, Evalue=1e-18,
Organism=Homo sapiens, GI27363457, Length=282, Percent_Identity=26.5957446808511, Blast_Score=75, Evalue=2e-13,
Organism=Homo sapiens, GI34147522, Length=277, Percent_Identity=25.6317689530686, Blast_Score=70, Evalue=4e-12,
Organism=Homo sapiens, GI217416386, Length=251, Percent_Identity=25.8964143426295, Blast_Score=69, Evalue=1e-11,
Organism=Escherichia coli, GI2367309, Length=393, Percent_Identity=29.2620865139949, Blast_Score=165, Evalue=9e-42,
Organism=Caenorhabditis elegans, GI17559152, Length=254, Percent_Identity=31.1023622047244, Blast_Score=121, Evalue=1e-27,
Organism=Caenorhabditis elegans, GI32565180, Length=290, Percent_Identity=29.6551724137931, Blast_Score=99, Evalue=7e-21,
Organism=Saccharomyces cerevisiae, GI6325148, Length=262, Percent_Identity=31.2977099236641, Blast_Score=115, Evalue=2e-26,
Organism=Saccharomyces cerevisiae, GI6321319, Length=256, Percent_Identity=31.640625, Blast_Score=102, Evalue=2e-22,
Organism=Saccharomyces cerevisiae, GI6323282, Length=293, Percent_Identity=26.962457337884, Blast_Score=92, Evalue=2e-19,
Organism=Drosophila melanogaster, GI24662575, Length=252, Percent_Identity=29.7619047619048, Blast_Score=122, Evalue=1e-27,
Organism=Drosophila melanogaster, GI22024280, Length=265, Percent_Identity=31.6981132075472, Blast_Score=120, Evalue=3e-27,
Organism=Drosophila melanogaster, GI18859849, Length=261, Percent_Identity=24.904214559387, Blast_Score=80, Evalue=6e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004147
- InterPro:   IPR011009
- InterPro:   IPR010232 [H]

Pfam domain/function: PF03109 ABC1 [H]

EC number: NA

Molecular weight: Translated: 73147; Mature: 73147

Theoretical pI: Translated: 7.08; Mature: 7.08

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFFQFFLLAVIMSFISGRLIGTKLNFFKQASAATLGVSLTSAMYWFLYLRYQDESIVGVD
CHHHHHHHHHHHHHHCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCEEEHH
RYFWLGSSLIVSMLCYLVFELFDPIKRSEMDDVVIESRNPISKFFAKIGRQKRYMRVSSI
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHCCCCCCHHHHHHHHCCHHHHHHHHHH
AIKHGMGKYLALKRSPEADRKLATSLRNTLEECGGVFIKFGQVLSTRSDLLPPVFIHELS
HHHHCCCHHEEECCCCCHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHCCCHHHHHHHH
NLQENVTRLSQQQVEEILNKELHIPKDEIFSSFEMEPLAAASIGQVHKAKLKENDQDVVV
HHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCHHHHH
KLLRPNISETIKRDLDILIHFALWISNKSTWAKNIGFLDLAQGFSTAMKEEIDFKIEARN
HHHCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHCCCHHHHHHHHHHHHHHHCCEEEECCC
FEQVSDSLKNSETKVKIPEVYQEYSNSKILVLEFLDGVSVKSGAALLNELQIDTKKVQRQ
HHHHHHHHHCCCCEEECHHHHHHHCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHH
LFDCILEQIFFKGIFHADPHPGNVYILRDGTPALLDFGSVGRLGTLQQEAFKRLLIGFER
HHHHHHHHHHHHHCCCCCCCCCEEEEEECCCCHHCCCCCCCCCCHHHHHHHHHHHHHHCC
KNSYVLLDGLLQLVEKKPNVDKEGLEQSISQLLIQSTYVSTNSSEEFIQGLFQIIAEFEL
CCCEEEHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHH
AFYPMVAGAFRSLITLEGTMLQLNPEFNLMDEAKRFAKDHVASFMPVNNYSSLKEAATNE
HHHHHHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHH
LLSMLPAMRRIPRKLDDLSSKLENGELSVKVGFFSDETNASFITTFISQFLIAFIGTAFG
HHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHH
GISVGVLHLANNAKEPNDQFLSVVGYGGLFISAILLVRVAIHAVRKFK
HHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MFFQFFLLAVIMSFISGRLIGTKLNFFKQASAATLGVSLTSAMYWFLYLRYQDESIVGVD
CHHHHHHHHHHHHHHCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCEEEHH
RYFWLGSSLIVSMLCYLVFELFDPIKRSEMDDVVIESRNPISKFFAKIGRQKRYMRVSSI
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHCCCCCCHHHHHHHHCCHHHHHHHHHH
AIKHGMGKYLALKRSPEADRKLATSLRNTLEECGGVFIKFGQVLSTRSDLLPPVFIHELS
HHHHCCCHHEEECCCCCHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHCCCHHHHHHHH
NLQENVTRLSQQQVEEILNKELHIPKDEIFSSFEMEPLAAASIGQVHKAKLKENDQDVVV
HHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCHHHHH
KLLRPNISETIKRDLDILIHFALWISNKSTWAKNIGFLDLAQGFSTAMKEEIDFKIEARN
HHHCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHCCCHHHHHHHHHHHHHHHCCEEEECCC
FEQVSDSLKNSETKVKIPEVYQEYSNSKILVLEFLDGVSVKSGAALLNELQIDTKKVQRQ
HHHHHHHHHCCCCEEECHHHHHHHCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHH
LFDCILEQIFFKGIFHADPHPGNVYILRDGTPALLDFGSVGRLGTLQQEAFKRLLIGFER
HHHHHHHHHHHHHCCCCCCCCCEEEEEECCCCHHCCCCCCCCCCHHHHHHHHHHHHHHCC
KNSYVLLDGLLQLVEKKPNVDKEGLEQSISQLLIQSTYVSTNSSEEFIQGLFQIIAEFEL
CCCEEEHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHH
AFYPMVAGAFRSLITLEGTMLQLNPEFNLMDEAKRFAKDHVASFMPVNNYSSLKEAATNE
HHHHHHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHH
LLSMLPAMRRIPRKLDDLSSKLENGELSVKVGFFSDETNASFITTFISQFLIAFIGTAFG
HHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHH
GISVGVLHLANNAKEPNDQFLSVVGYGGLFISAILLVRVAIHAVRKFK
HHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: 2 2-octaprenylphenol; O2 [C]

Specific reaction: 2 2-octaprenylphenol + O2 = 2 2-octaprenyl-6-hydroxyphenol [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA