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The map label for this gene is cotH [H]

Identifier: 218903194

GI number: 218903194

Start: 1975694

End: 1976770

Strand: Direct

Name: cotH [H]

Synonym: BCAH820_2078

Alternate gene names: 218903194

Gene position: 1975694-1976770 (Clockwise)

Preceding gene: 218903192

Following gene: 218903195

Centisome position: 37.26

GC content: 30.83

Gene sequence:

>1077_bases
ATGCTACCTTCATATGATTTTTTTATTCATCCAATGTACGTAGTGGAATTGAAAAAAGACATTTGGTCAGACAGTCCAGT
ACCAGCAAAATTAACTTATGGAAAAAAGAAGTATGATATTGATATCGTATATCGGGGTGCTCATATTCGTGAATTTGAGA
AAAAGTCTTATCATGTTATGTTTTATAAGCCAAAAAAATTTCAAGGTGCGAAAGAGTTTCATTTAAATTCTGAGTTTATG
GATCCGTCTCTCATACGAAATAAATTATCTTTAGATTTTTTTCATGATATTGGTGTACTTTCACCAAAATCACAACATGT
ATTTATAAAAATTAATGGTCAAATTCAAGGAGTATATTTACAGTTAGAATCAGTTGATGAAAACTTTTTGAAAAATAGAG
GATTACCTAGTGGTTCTATTTATTATGCGATAGATGATGATGCGAATTTCTCTTTAATGAGTGAAAGAGATAAAGATGTT
AAGACTGAGCTTTTTGCGGGTTATGAATTTAAATATTCGAATGAACATAGTGAAGAACAATTGAGTGAATTTGTATTTCA
AGCGAACGCTTTGTCGAGGGAAGCGTATGAAAAAGAAATTGGGAAGTTTCTAAATGTTGATAAGTATTTACGATGGTTAG
CAGGCGTTATTTTTACACAAAACTTTGATGGTTTTGTTCATAACTATGCATTATACCATAACGATGAAACAAATTTATTT
GAAGTGATACCGTGGGATTATGATGCGACTTGGGGGCGTGATGTACAAGGGAGACCGCTTAATCATGAATATATTCGTAT
TCAAGGTTATAACACGTTAAGTGCAAGATTGTTAGATATACCTGTATTTAGAAAACAATACCGAAGTATTTTGGAAGAAA
TATTAGAAGAACAATTTACGGTTTCATTTATGATGCCGAAAGTAGAAAGTTTATGTGAAGCAATACGTCCTTATTTACTA
CAAGATCCATATATGAAAGAAAAATTAGAAACCTTTGATCAAGAACCTGGTGTGATTGAGGAATATATAAATAAAAGAAG
AAAGTATATACAAGATCATTTACATGAATTGGATTAA

Upstream 100 bases:

>100_bases
AGGACAAGAGTGTAATTTTATATAAATGGTTGATAGCGGATGTATGGACAAGGAGAAGTGCATACATTGAATGAAGAGAA
CTGAGAAGGGATGTGAAAAT

Downstream 100 bases:

>100_bases
TTTTGAAAGAGATTGGAACATTATCAATCTCTTTTTTTGTATAATAAAGATGTATGAATAAAATTGACGTAATATTTACT
TAATAAAGAATAGGGATGTG

Product: spore coat protein H

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 358; Mature: 358

Protein sequence:

>358_residues
MLPSYDFFIHPMYVVELKKDIWSDSPVPAKLTYGKKKYDIDIVYRGAHIREFEKKSYHVMFYKPKKFQGAKEFHLNSEFM
DPSLIRNKLSLDFFHDIGVLSPKSQHVFIKINGQIQGVYLQLESVDENFLKNRGLPSGSIYYAIDDDANFSLMSERDKDV
KTELFAGYEFKYSNEHSEEQLSEFVFQANALSREAYEKEIGKFLNVDKYLRWLAGVIFTQNFDGFVHNYALYHNDETNLF
EVIPWDYDATWGRDVQGRPLNHEYIRIQGYNTLSARLLDIPVFRKQYRSILEEILEEQFTVSFMMPKVESLCEAIRPYLL
QDPYMKEKLETFDQEPGVIEEYINKRRKYIQDHLHELD

Sequences:

>Translated_358_residues
MLPSYDFFIHPMYVVELKKDIWSDSPVPAKLTYGKKKYDIDIVYRGAHIREFEKKSYHVMFYKPKKFQGAKEFHLNSEFM
DPSLIRNKLSLDFFHDIGVLSPKSQHVFIKINGQIQGVYLQLESVDENFLKNRGLPSGSIYYAIDDDANFSLMSERDKDV
KTELFAGYEFKYSNEHSEEQLSEFVFQANALSREAYEKEIGKFLNVDKYLRWLAGVIFTQNFDGFVHNYALYHNDETNLF
EVIPWDYDATWGRDVQGRPLNHEYIRIQGYNTLSARLLDIPVFRKQYRSILEEILEEQFTVSFMMPKVESLCEAIRPYLL
QDPYMKEKLETFDQEPGVIEEYINKRRKYIQDHLHELD
>Mature_358_residues
MLPSYDFFIHPMYVVELKKDIWSDSPVPAKLTYGKKKYDIDIVYRGAHIREFEKKSYHVMFYKPKKFQGAKEFHLNSEFM
DPSLIRNKLSLDFFHDIGVLSPKSQHVFIKINGQIQGVYLQLESVDENFLKNRGLPSGSIYYAIDDDANFSLMSERDKDV
KTELFAGYEFKYSNEHSEEQLSEFVFQANALSREAYEKEIGKFLNVDKYLRWLAGVIFTQNFDGFVHNYALYHNDETNLF
EVIPWDYDATWGRDVQGRPLNHEYIRIQGYNTLSARLLDIPVFRKQYRSILEEILEEQFTVSFMMPKVESLCEAIRPYLL
QDPYMKEKLETFDQEPGVIEEYINKRRKYIQDHLHELD

Specific function: Involved in the assembly of several proteins in the inner and outer layer of the spore coat. Stabilizes CotC and CotU in the mother cell compartment of sporulating cells and promotes the assembly of both early and late forms of CotC-related polypeptides o

COG id: COG5337

COG function: function code M; Spore coat assembly protein

Gene ontology:

Cell location: Spore wall, spore coat [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CotH family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014867 [H]

Pfam domain/function: PF08757 CotH [H]

EC number: NA

Molecular weight: Translated: 42524; Mature: 42524

Theoretical pI: Translated: 5.46; Mature: 5.46

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLPSYDFFIHPMYVVELKKDIWSDSPVPAKLTYGKKKYDIDIVYRGAHIREFEKKSYHVM
CCCCCCEEECCCEEEEEHHHHCCCCCCCEEEECCCEEEEEEEEEECCHHHHHCCCCEEEE
FYKPKKFQGAKEFHLNSEFMDPSLIRNKLSLDFFHDIGVLSPKSQHVFIKINGQIQGVYL
EECCHHCCCCHHEECCCCCCCHHHHHHHHCHHHHHHCCCCCCCCCEEEEEECCEEEEEEE
QLESVDENFLKNRGLPSGSIYYAIDDDANFSLMSERDKDVKTELFAGYEFKYSNEHSEEQ
EEEHHHHHHHHHCCCCCCEEEEEECCCCCEEECCCCCCCHHHHHHCCEEEEECCCCCHHH
LSEFVFQANALSREAYEKEIGKFLNVDKYLRWLAGVIFTQNFDGFVHNYALYHNDETNLF
HHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCHHHEEEEEECCCCCEE
EVIPWDYDATWGRDVQGRPLNHEYIRIQGYNTLSARLLDIPVFRKQYRSILEEILEEQFT
EEECCCCCCCCCCCCCCCCCCCCEEEEECCCCHHHHHHHCHHHHHHHHHHHHHHHHHHHE
VSFMMPKVESLCEAIRPYLLQDPYMKEKLETFDQEPGVIEEYINKRRKYIQDHLHELD
EHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MLPSYDFFIHPMYVVELKKDIWSDSPVPAKLTYGKKKYDIDIVYRGAHIREFEKKSYHVM
CCCCCCEEECCCEEEEEHHHHCCCCCCCEEEECCCEEEEEEEEEECCHHHHHCCCCEEEE
FYKPKKFQGAKEFHLNSEFMDPSLIRNKLSLDFFHDIGVLSPKSQHVFIKINGQIQGVYL
EECCHHCCCCHHEECCCCCCCHHHHHHHHCHHHHHHCCCCCCCCCEEEEEECCEEEEEEE
QLESVDENFLKNRGLPSGSIYYAIDDDANFSLMSERDKDVKTELFAGYEFKYSNEHSEEQ
EEEHHHHHHHHHCCCCCCEEEEEECCCCCEEECCCCCCCHHHHHHCCEEEEECCCCCHHH
LSEFVFQANALSREAYEKEIGKFLNVDKYLRWLAGVIFTQNFDGFVHNYALYHNDETNLF
HHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCHHHEEEEEECCCCCEE
EVIPWDYDATWGRDVQGRPLNHEYIRIQGYNTLSARLLDIPVFRKQYRSILEEILEEQFT
EEECCCCCCCCCCCCCCCCCCCCEEEEECCCCHHHHHHHCHHHHHHHHHHHHHHHHHHHE
VSFMMPKVESLCEAIRPYLLQDPYMKEKLETFDQEPGVIEEYINKRRKYIQDHLHELD
EHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8755863; 8991897; 9353933; 9384377; 7814326; 10198031 [H]