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The map label for this gene is yciC [H]

Identifier: 218903078

GI number: 218903078

Start: 1868743

End: 1869666

Strand: Direct

Name: yciC [H]

Synonym: BCAH820_1961

Alternate gene names: 218903078

Gene position: 1868743-1869666 (Clockwise)

Preceding gene: 218903077

Following gene: 218903080

Centisome position: 35.24

GC content: 32.9

Gene sequence:

>924_bases
ATGAATAAAGTAGAAATTCATATATTAGGTGGCTTTTTAGGTAGCGGAAAATCAACATTATTACAAAATTTATTGTTAGC
GGAGAAAAAGAAGAATAGAAAAGTTGCAGTGTTAATGAATGAAATTGGTGAATACTCAGTAGATACAGATATTATTGGAA
AAGAGAATGTTTTAAGGGAACTTCTTAAAGGGTGTATTTGTTGTACGTTAAAAGAAGAGCTTGAAATACAATTACATTCG
TTATATCAGCAAGAAAGACCAGATGTCATTTATATAGAAACGACAGGTGTTGCGCATCCAATTGAAGTGCTAGATGCATG
TGTATCACCAATTTTAGCACCTTTCTTAGAAGTGAAATCAATAGTAGTCGTTTTAGATGCAGTAAGGTGGTTAAATCGAA
GAGTATTAAGTGCAAACGTTCAGCAATTATTACATGAGCAATTGAAGTTTGGTAGCCACATTTTAATTAATAAATCAGAT
TTACTAATAGAGGCGGATAAGAACAAAGTAATTGAAGAAGTGAAAGCGATAAATAATCATGCGAAATTGTTTGAAACAAA
ATATTGTAATATTTCTTTAGAAGACATAGAAGAAGCTGAATTTACGAATGACACGGAACATGAGACACTACATGTAAAAC
AGCATTTACATATACAAACGATGACGTATCAATTTACGAAATCAATTGATCAAGATAAATTATACGAATGGCTTTCGAAT
TTACCAGATAGTATTTATCGTGTGAAAGGTTTTGTGAAATTTCATGGGGACAAATATCCTCACTTATTCCAATACTCGTT
CGGGGTACCAACTTTACTGGAACAAGACTTCGGTTTCCCGACGAACTTGGTAGTGATAGGGGAAGGGCTAGATAAGAAAC
AATTGGCTGAAGGGTTAGAGAAAGTGGAACTTAATTCTAATTAA

Upstream 100 bases:

>100_bases
ATATTTACAAATCACGACTCTTTTAATAAAATAATAAATATAAATCGTAATTATTACGCTTTGAATACGTTTTGAAATAA
AGAAATGGATGGTCGATCAA

Downstream 100 bases:

>100_bases
GATTAAAGGGAGTTGCCCCATAAGTTGATGAAAACGACTTATGGGGCAGTCCTTTTATTTTTTATGAATAAGCATATAGA
TACTTGTATTCATTTTAAAT

Product: cobalamin synthesis protein/P47K family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 307; Mature: 307

Protein sequence:

>307_residues
MNKVEIHILGGFLGSGKSTLLQNLLLAEKKKNRKVAVLMNEIGEYSVDTDIIGKENVLRELLKGCICCTLKEELEIQLHS
LYQQERPDVIYIETTGVAHPIEVLDACVSPILAPFLEVKSIVVVLDAVRWLNRRVLSANVQQLLHEQLKFGSHILINKSD
LLIEADKNKVIEEVKAINNHAKLFETKYCNISLEDIEEAEFTNDTEHETLHVKQHLHIQTMTYQFTKSIDQDKLYEWLSN
LPDSIYRVKGFVKFHGDKYPHLFQYSFGVPTLLEQDFGFPTNLVVIGEGLDKKQLAEGLEKVELNSN

Sequences:

>Translated_307_residues
MNKVEIHILGGFLGSGKSTLLQNLLLAEKKKNRKVAVLMNEIGEYSVDTDIIGKENVLRELLKGCICCTLKEELEIQLHS
LYQQERPDVIYIETTGVAHPIEVLDACVSPILAPFLEVKSIVVVLDAVRWLNRRVLSANVQQLLHEQLKFGSHILINKSD
LLIEADKNKVIEEVKAINNHAKLFETKYCNISLEDIEEAEFTNDTEHETLHVKQHLHIQTMTYQFTKSIDQDKLYEWLSN
LPDSIYRVKGFVKFHGDKYPHLFQYSFGVPTLLEQDFGFPTNLVVIGEGLDKKQLAEGLEKVELNSN
>Mature_307_residues
MNKVEIHILGGFLGSGKSTLLQNLLLAEKKKNRKVAVLMNEIGEYSVDTDIIGKENVLRELLKGCICCTLKEELEIQLHS
LYQQERPDVIYIETTGVAHPIEVLDACVSPILAPFLEVKSIVVVLDAVRWLNRRVLSANVQQLLHEQLKFGSHILINKSD
LLIEADKNKVIEEVKAINNHAKLFETKYCNISLEDIEEAEFTNDTEHETLHVKQHLHIQTMTYQFTKSIDQDKLYEWLSN
LPDSIYRVKGFVKFHGDKYPHLFQYSFGVPTLLEQDFGFPTNLVVIGEGLDKKQLAEGLEKVELNSN

Specific function: May bind GTP. Might act as metal chaperone (Potential). Contributes to optimal growth under starvation for zinc [H]

COG id: COG0523

COG function: function code R; Putative GTPases (G3E family)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 cobW C-terminal domain [H]

Homologues:

Organism=Homo sapiens, GI126722884, Length=334, Percent_Identity=26.9461077844311, Blast_Score=84, Evalue=2e-16,
Organism=Homo sapiens, GI33469141, Length=334, Percent_Identity=26.9461077844311, Blast_Score=83, Evalue=3e-16,
Organism=Homo sapiens, GI148727351, Length=334, Percent_Identity=27.2455089820359, Blast_Score=82, Evalue=6e-16,
Organism=Homo sapiens, GI146231952, Length=337, Percent_Identity=27.299703264095, Blast_Score=80, Evalue=2e-15,
Organism=Homo sapiens, GI223941779, Length=200, Percent_Identity=31.5, Blast_Score=80, Evalue=3e-15,
Organism=Homo sapiens, GI223941776, Length=323, Percent_Identity=26.625386996904, Blast_Score=74, Evalue=2e-13,
Organism=Escherichia coli, GI1788499, Length=158, Percent_Identity=34.1772151898734, Blast_Score=102, Evalue=2e-23,
Organism=Escherichia coli, GI87082430, Length=299, Percent_Identity=28.0936454849498, Blast_Score=87, Evalue=1e-18,
Organism=Saccharomyces cerevisiae, GI6324356, Length=226, Percent_Identity=27.4336283185841, Blast_Score=76, Evalue=8e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003495
- InterPro:   IPR011629 [H]

Pfam domain/function: PF02492 cobW; PF07683 CobW_C [H]

EC number: NA

Molecular weight: Translated: 35038; Mature: 35038

Theoretical pI: Translated: 5.58; Mature: 5.58

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNKVEIHILGGFLGSGKSTLLQNLLLAEKKKNRKVAVLMNEIGEYSVDTDIIGKENVLRE
CCEEEEEEEECCCCCCHHHHHHHHHHHHHHCCCEEEEEEHHHCCCCCCCCCCCHHHHHHH
LLKGCICCTLKEELEIQLHSLYQQERPDVIYIETTGVAHPIEVLDACVSPILAPFLEVKS
HHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHH
IVVVLDAVRWLNRRVLSANVQQLLHEQLKFGSHILINKSDLLIEADKNKVIEEVKAINNH
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCEEEECCHHHHHHHHHHHHHH
AKLFETKYCNISLEDIEEAEFTNDTEHETLHVKQHLHIQTMTYQFTKSIDQDKLYEWLSN
HHHHHHEECCCCHHHHHHHHCCCCCCCCEEEHHHHEEEEHHHHHHHHCCCHHHHHHHHHC
LPDSIYRVKGFVKFHGDKYPHLFQYSFGVPTLLEQDFGFPTNLVVIGEGLDKKQLAEGLE
CCHHHHHHHHHEEECCCCCCEEEEECCCCCHHHHHCCCCCCEEEEEECCCCHHHHHHHHH
KVELNSN
HHCCCCC
>Mature Secondary Structure
MNKVEIHILGGFLGSGKSTLLQNLLLAEKKKNRKVAVLMNEIGEYSVDTDIIGKENVLRE
CCEEEEEEEECCCCCCHHHHHHHHHHHHHHCCCEEEEEEHHHCCCCCCCCCCCHHHHHHH
LLKGCICCTLKEELEIQLHSLYQQERPDVIYIETTGVAHPIEVLDACVSPILAPFLEVKS
HHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHH
IVVVLDAVRWLNRRVLSANVQQLLHEQLKFGSHILINKSDLLIEADKNKVIEEVKAINNH
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCEEEECCHHHHHHHHHHHHHH
AKLFETKYCNISLEDIEEAEFTNDTEHETLHVKQHLHIQTMTYQFTKSIDQDKLYEWLSN
HHHHHHEECCCCHHHHHHHHCCCCCCCCEEEHHHHEEEEHHHHHHHHCCCHHHHHHHHHC
LPDSIYRVKGFVKFHGDKYPHLFQYSFGVPTLLEQDFGFPTNLVVIGEGLDKKQLAEGLE
CCHHHHHHHHHEEECCCCCCEEEEECCCCCHHHHHCCCCCCEEEEEECCCCHHHHHHHHH
KVELNSN
HHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8969502; 9384377; 9811636 [H]