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The map label for this gene is capA [H]

Identifier: 218903010

GI number: 218903010

Start: 1794520

End: 1795623

Strand: Reverse

Name: capA [H]

Synonym: BCAH820_1893

Alternate gene names: 218903010

Gene position: 1795623-1794520 (Counterclockwise)

Preceding gene: 218903014

Following gene: 218903003

Centisome position: 33.86

GC content: 34.6

Gene sequence:

>1104_bases
ATGAAAACTTTACTAAAACGATTTTTGTTAATAGCCTTTTGTATTACACCAATTGTTGTATTAATTAACCACTCTTTTAC
TTCAAAGGCGACAGACAAACCCGATTTCCAAAACAAATCTAGTAAAACTGCTTCAAAAAGCGACAAGAAAATAGAAGACC
CGGAAATTACACTCACCTTCTCTGGTGATACAATGTTCGATTGGCAATTACGTCCGGTAATCGAAAAAAACGGGGCTGAT
TATCCATTCCAGCATGTAAAAGAAGAAATAACAAAAGCTGATATTTCTTTCGTTAATTTAGAGTCAGCATTTACAACGAA
AGAAAAGAAAGCTCCTGGACAACTGTTTTGGATTAAAAGTGATCCATCCACGCTTAAAGCGATAAAAAACACTGGATATG
ACATCGTAAATATTGGGAATAACCATACACTTGATTATGGACAAAATGGATTATTAGACACGATCTCTCACGTAGAGAAA
TTAAAGTTCCCTTACATTGGAGCCGGAAAAAATGCAAAAGATGCATATACTGCACGAGAAATGACTGTAAAAGGAAAAAA
ATTCAAATTCCTTTCATTCGTCCGATTTATGCCTGATTTTACTTGGGTAGCTGATGACAATAAACCTGGCGTTGCGAACG
GGTATGATTTAAATCTTGTAACAAAAACAATTAAAGAGCAAAAGAAAGATGCAGACTATTTAATTGTCTATATGCATTGG
GGTGTCGAAAAATCAAATCGTCCGGTAGATTATCAAAAACAATATGTAAATAAAATGGTTACAGCAGGAGCCGACGCGAT
TGTCGGAAGTCATCCACATTGGTTACAAGGGTTTGAATATTATAATAACGTTCCTGTCGCTTACTCATTAGGAAACTTTT
TATTCCCAAGTTATGTGAACGGAAAAAGTGCTGAAACTGGTGTATTAACTTTAACTTTTAAAGGAAAGGATGTCCAAATG
TCATTCAATCCTTATATCATCCGTAACAACCAAGTTTCCCCTGTAAATGAGGAAGAAAAGAGAAAAGCTCTCCAATACTT
ACAAACAATTTCAACTGATGTAGAAATTGATGATACAGGGAAAATAATAAATAAACGCAACTAA

Upstream 100 bases:

>100_bases
AACATAAACCGCATTTTTTTGTATCTGTACATACACCAATTACTTTTTATAGACTCATTGCTAATCTAATTGCGAGATAA
ACTCAAAAGGGAAGGTATTT

Downstream 100 bases:

>100_bases
ACAGTACAAGATCCATTTCTCTGTAACATACATTAGAGAATAGGTGATGAATATGCTAAAGGGCTTATTAGAAAATATAG
TTCTCTTAGAAAATATCTAT

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 367; Mature: 367

Protein sequence:

>367_residues
MKTLLKRFLLIAFCITPIVVLINHSFTSKATDKPDFQNKSSKTASKSDKKIEDPEITLTFSGDTMFDWQLRPVIEKNGAD
YPFQHVKEEITKADISFVNLESAFTTKEKKAPGQLFWIKSDPSTLKAIKNTGYDIVNIGNNHTLDYGQNGLLDTISHVEK
LKFPYIGAGKNAKDAYTAREMTVKGKKFKFLSFVRFMPDFTWVADDNKPGVANGYDLNLVTKTIKEQKKDADYLIVYMHW
GVEKSNRPVDYQKQYVNKMVTAGADAIVGSHPHWLQGFEYYNNVPVAYSLGNFLFPSYVNGKSAETGVLTLTFKGKDVQM
SFNPYIIRNNQVSPVNEEEKRKALQYLQTISTDVEIDDTGKIINKRN

Sequences:

>Translated_367_residues
MKTLLKRFLLIAFCITPIVVLINHSFTSKATDKPDFQNKSSKTASKSDKKIEDPEITLTFSGDTMFDWQLRPVIEKNGAD
YPFQHVKEEITKADISFVNLESAFTTKEKKAPGQLFWIKSDPSTLKAIKNTGYDIVNIGNNHTLDYGQNGLLDTISHVEK
LKFPYIGAGKNAKDAYTAREMTVKGKKFKFLSFVRFMPDFTWVADDNKPGVANGYDLNLVTKTIKEQKKDADYLIVYMHW
GVEKSNRPVDYQKQYVNKMVTAGADAIVGSHPHWLQGFEYYNNVPVAYSLGNFLFPSYVNGKSAETGVLTLTFKGKDVQM
SFNPYIIRNNQVSPVNEEEKRKALQYLQTISTDVEIDDTGKIINKRN
>Mature_367_residues
MKTLLKRFLLIAFCITPIVVLINHSFTSKATDKPDFQNKSSKTASKSDKKIEDPEITLTFSGDTMFDWQLRPVIEKNGAD
YPFQHVKEEITKADISFVNLESAFTTKEKKAPGQLFWIKSDPSTLKAIKNTGYDIVNIGNNHTLDYGQNGLLDTISHVEK
LKFPYIGAGKNAKDAYTAREMTVKGKKFKFLSFVRFMPDFTWVADDNKPGVANGYDLNLVTKTIKEQKKDADYLIVYMHW
GVEKSNRPVDYQKQYVNKMVTAGADAIVGSHPHWLQGFEYYNNVPVAYSLGNFLFPSYVNGKSAETGVLTLTFKGKDVQM
SFNPYIIRNNQVSPVNEEEKRKALQYLQTISTDVEIDDTGKIINKRN

Specific function: Essential for the synthesis of the polyglutamate capsule of B.anthracis which is one of the principal virulence factors during anthrax infection. May form a polyglutamyl synthetase complex together with proteins CapB and CapC [H]

COG id: COG2843

COG function: function code M; Putative enzyme of poly-gamma-glutamate biosynthesis (capsule formation)

Gene ontology:

Cell location: Cell membrane; Single-pass membrane protein [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CapA family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR019079 [H]

Pfam domain/function: PF09587 PGA_cap [H]

EC number: NA

Molecular weight: Translated: 41653; Mature: 41653

Theoretical pI: Translated: 9.50; Mature: 9.50

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKTLLKRFLLIAFCITPIVVLINHSFTSKATDKPDFQNKSSKTASKSDKKIEDPEITLTF
CHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEE
SGDTMFDWQLRPVIEKNGADYPFQHVKEEITKADISFVNLESAFTTKEKKAPGQLFWIKS
CCCEEEEEEECCCEECCCCCCCHHHHHHHHHHHCCEEEEEHHHHCCCCCCCCCEEEEEEC
DPSTLKAIKNTGYDIVNIGNNHTLDYGQNGLLDTISHVEKLKFPYIGAGKNAKDAYTARE
CCHHHHHHHHCCCEEEECCCCCEECCCCCCHHHHHHHHHHHCCCEECCCCCCCHHHHHHH
MTVKGKKFKFLSFVRFMPDFTWVADDNKPGVANGYDLNLVTKTIKEQKKDADYLIVYMHW
EEECCCHHHHHHHHHHCCCEEEEECCCCCCCCCCCCHHHHHHHHHHHCCCCCEEEEEEEE
GVEKSNRPVDYQKQYVNKMVTAGADAIVGSHPHWLQGFEYYNNVPVAYSLGNFLFPSYVN
CCCCCCCCCCHHHHHHHHHHHCCCCHHCCCCCHHHHHHHHHCCCCEEEECCCCCCCCCCC
GKSAETGVLTLTFKGKDVQMSFNPYIIRNNQVSPVNEEEKRKALQYLQTISTDVEIDDTG
CCCCCCEEEEEEECCCEEEEECCCEEEECCCCCCCCHHHHHHHHHHHHHHCCCCEECCCC
KIINKRN
CCCCCCC
>Mature Secondary Structure
MKTLLKRFLLIAFCITPIVVLINHSFTSKATDKPDFQNKSSKTASKSDKKIEDPEITLTF
CHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEE
SGDTMFDWQLRPVIEKNGADYPFQHVKEEITKADISFVNLESAFTTKEKKAPGQLFWIKS
CCCEEEEEEECCCEECCCCCCCHHHHHHHHHHHCCEEEEEHHHHCCCCCCCCCEEEEEEC
DPSTLKAIKNTGYDIVNIGNNHTLDYGQNGLLDTISHVEKLKFPYIGAGKNAKDAYTARE
CCHHHHHHHHCCCEEEECCCCCEECCCCCCHHHHHHHHHHHCCCEECCCCCCCHHHHHHH
MTVKGKKFKFLSFVRFMPDFTWVADDNKPGVANGYDLNLVTKTIKEQKKDADYLIVYMHW
EEECCCHHHHHHHHHHCCCEEEEECCCCCCCCCCCCHHHHHHHHHHHCCCCCEEEEEEEE
GVEKSNRPVDYQKQYVNKMVTAGADAIVGSHPHWLQGFEYYNNVPVAYSLGNFLFPSYVN
CCCCCCCCCCHHHHHHHHHHHCCCCHHCCCCCHHHHHHHHHCCCCEEEECCCCCCCCCCC
GKSAETGVLTLTFKGKDVQMSFNPYIIRNNQVSPVNEEEKRKALQYLQTISTDVEIDDTG
CCCCCCEEEEEEECCCEEEEECCCEEEECCCCCCCCHHHHHHHHHHHHHHCCCCEECCCC
KIINKRN
CCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2536679; 10475962; 12004073 [H]