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The map label for this gene is dsdA [H]

Identifier: 218902950

GI number: 218902950

Start: 1726381

End: 1727775

Strand: Direct

Name: dsdA [H]

Synonym: BCAH820_1833

Alternate gene names: 218902950

Gene position: 1726381-1727775 (Clockwise)

Preceding gene: 218902949

Following gene: 218902951

Centisome position: 32.56

GC content: 36.49

Gene sequence:

>1395_bases
TTGGTTCGCCAACAATTTATAGATTTTTATAAGAATTTTAAACCAGGAAGAGGAATGAAGGAAATAGAGAAATTAAAAGA
GGAATATCCACTATTAAATAAATTGATTGAAATAGAAGAAGTGTTTTGGGTGAATCCGAACATGGAAAAGTATGAAACGG
CAATAAAAGATTCGCCACTCAGTGAAGAGAATGTAAAAGATGCGGAGGAGAGGTTAAAGCGTTTTGCATCATACATTGCG
AAAGTTTTTCCTGAAACGAAAGACACAGGCGGTATTATAGAATCACCTTTAGTGAAGATACCTTCTATGAAACAGTCTTT
AGAGAAAAATTACGAGCAACCTATATTAGGAGAATTATTATTAAAATGTGATAGTCATCTCCCGATATCAGGATCAATTA
AAGCTAGAGGCGGCATTTATGAAGTGTTGAAACATGCTGAACAATTAGCTTTGCAGCAAGGTATGTTAACAGAAGAAGAT
GATTATTCCATTTTAGATAGTGATACATGTAGAGAGTTTTTTGCCACTTATTCCATCGCGGTAGGTTCGACAGGGAATTT
AGGATTAAGTATTGGGATTATGAGTGCGAAGTTAGGTTTTAACGTAACGGTTCATATGTCAGCAGACGCGAAACAATGGA
AAAAAGATTTATTAAGAAGTAAAGGTGTAAATGTTATTGAATATGAAGCTGATTATAGTAAAGCTGTAGAAGAAGGAAGA
AGGCAAGCAGATGCTGATCCTAGCTGTTATTTTGTAGATGATGAAAACTCACATGATTTATTTTTAGGATACGCAGTAGC
GGCATCGCGTTTACAAAAACAATTAGAAGAGTTAGAGATTATAGTGGATGAAGAGCATCCTTTATTCGTTTATCTGCCAT
GCGGAGTAGGTGGCGGACCTGGCGGAGTCGCATTTGGTTTAAAGTTATTGTATAAAGACAACGTACACTGTTTCTTTGCA
GAGCCAACACATTCTCCATGTATGTTAATCGGGTTAATGACAGGACTTCATGATAAAATCGCCGTTCAAGATATCGGAAT
TGATAATGTAACAGACGCAGACGGACTTGCGGTAGGAAGGCCATCTGGATTTGTTGGTAAAACGATGGAACCATTTTTGA
GCGGGAATTACACAGTAAGTGATGAAGAATTGTATAGGTTGTTAAAAGAGCTAGCTGATACGGAAAATATTTATTTAGAG
CCTTCTGCATTAGCAGGTATGATAGGACCAGTAAAAGTATGTAAAGAAGATGCGTATTTACAAGAGCAACAGTTAATGGA
GAAGATGAAAAAAGGTACTCATATTGTATGGGGAACGGGCGGTAGTATGGTTCCAGAAGATGTGATGAATGGGTATTATA
AAACAGGTGAGGCATTAACAATATTAGAAAAATGA

Upstream 100 bases:

>100_bases
AGGAACCTGCCGTCATTCTTTCACAATAGGTGGATGAAAAGGTCACAAATCTTACGGACAGGAAAAAGGTGAGATTCCTT
TTCGGTAGTTGGCATTTGAC

Downstream 100 bases:

>100_bases
GGCTAGATGTAGCCTCATTTTTTCATGTACATAAAAATCTTTGTTATTTTCACAATAGTTCTTTATAGTATAGATAAAGG
ATAACTAATATTGAATAAAT

Product: D-serine dehydratase

Products: NA

Alternate protein names: D-serine deaminase; DSD [H]

Number of amino acids: Translated: 464; Mature: 464

Protein sequence:

>464_residues
MVRQQFIDFYKNFKPGRGMKEIEKLKEEYPLLNKLIEIEEVFWVNPNMEKYETAIKDSPLSEENVKDAEERLKRFASYIA
KVFPETKDTGGIIESPLVKIPSMKQSLEKNYEQPILGELLLKCDSHLPISGSIKARGGIYEVLKHAEQLALQQGMLTEED
DYSILDSDTCREFFATYSIAVGSTGNLGLSIGIMSAKLGFNVTVHMSADAKQWKKDLLRSKGVNVIEYEADYSKAVEEGR
RQADADPSCYFVDDENSHDLFLGYAVAASRLQKQLEELEIIVDEEHPLFVYLPCGVGGGPGGVAFGLKLLYKDNVHCFFA
EPTHSPCMLIGLMTGLHDKIAVQDIGIDNVTDADGLAVGRPSGFVGKTMEPFLSGNYTVSDEELYRLLKELADTENIYLE
PSALAGMIGPVKVCKEDAYLQEQQLMEKMKKGTHIVWGTGGSMVPEDVMNGYYKTGEALTILEK

Sequences:

>Translated_464_residues
MVRQQFIDFYKNFKPGRGMKEIEKLKEEYPLLNKLIEIEEVFWVNPNMEKYETAIKDSPLSEENVKDAEERLKRFASYIA
KVFPETKDTGGIIESPLVKIPSMKQSLEKNYEQPILGELLLKCDSHLPISGSIKARGGIYEVLKHAEQLALQQGMLTEED
DYSILDSDTCREFFATYSIAVGSTGNLGLSIGIMSAKLGFNVTVHMSADAKQWKKDLLRSKGVNVIEYEADYSKAVEEGR
RQADADPSCYFVDDENSHDLFLGYAVAASRLQKQLEELEIIVDEEHPLFVYLPCGVGGGPGGVAFGLKLLYKDNVHCFFA
EPTHSPCMLIGLMTGLHDKIAVQDIGIDNVTDADGLAVGRPSGFVGKTMEPFLSGNYTVSDEELYRLLKELADTENIYLE
PSALAGMIGPVKVCKEDAYLQEQQLMEKMKKGTHIVWGTGGSMVPEDVMNGYYKTGEALTILEK
>Mature_464_residues
MVRQQFIDFYKNFKPGRGMKEIEKLKEEYPLLNKLIEIEEVFWVNPNMEKYETAIKDSPLSEENVKDAEERLKRFASYIA
KVFPETKDTGGIIESPLVKIPSMKQSLEKNYEQPILGELLLKCDSHLPISGSIKARGGIYEVLKHAEQLALQQGMLTEED
DYSILDSDTCREFFATYSIAVGSTGNLGLSIGIMSAKLGFNVTVHMSADAKQWKKDLLRSKGVNVIEYEADYSKAVEEGR
RQADADPSCYFVDDENSHDLFLGYAVAASRLQKQLEELEIIVDEEHPLFVYLPCGVGGGPGGVAFGLKLLYKDNVHCFFA
EPTHSPCMLIGLMTGLHDKIAVQDIGIDNVTDADGLAVGRPSGFVGKTMEPFLSGNYTVSDEELYRLLKELADTENIYLE
PSALAGMIGPVKVCKEDAYLQEQQLMEKMKKGTHIVWGTGGSMVPEDVMNGYYKTGEALTILEK

Specific function: Unknown

COG id: COG3048

COG function: function code E; D-serine dehydratase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the serine/threonine dehydratase family. DsdA subfamily [H]

Homologues:

Organism=Escherichia coli, GI1788708, Length=438, Percent_Identity=62.5570776255708, Blast_Score=547, Evalue=1e-157,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011780
- InterPro:   IPR001926
- InterPro:   IPR000634 [H]

Pfam domain/function: PF00291 PALP [H]

EC number: =4.3.1.18 [H]

Molecular weight: Translated: 51710; Mature: 51710

Theoretical pI: Translated: 4.59; Mature: 4.59

Prosite motif: PS00165 DEHYDRATASE_SER_THR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVRQQFIDFYKNFKPGRGMKEIEKLKEEYPLLNKLIEIEEVFWVNPNMEKYETAIKDSPL
CCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHEEEECCCHHHHHHHHCCCCC
SEENVKDAEERLKRFASYIAKVFPETKDTGGIIESPLVKIPSMKQSLEKNYEQPILGELL
CCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHCCCHHHHHHHHCCCCCHHHHHH
LKCDSHLPISGSIKARGGIYEVLKHAEQLALQQGMLTEEDDYSILDSDTCREFFATYSIA
HHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHEE
VGSTGNLGLSIGIMSAKLGFNVTVHMSADAKQWKKDLLRSKGVNVIEYEADYSKAVEEGR
ECCCCCCEEEEEEEEEECCCEEEEEECCCHHHHHHHHHHHCCCCEEEECCHHHHHHHHHH
RQADADPSCYFVDDENSHDLFLGYAVAASRLQKQLEELEIIVDEEHPLFVYLPCGVGGGP
HHCCCCCCEEEECCCCCCEEEHHHHHHHHHHHHHHHHHEEEECCCCCEEEEEECCCCCCC
GGVAFGLKLLYKDNVHCFFAEPTHSPCMLIGLMTGLHDKIAVQDIGIDNVTDADGLAVGR
CHHHHHHHHEEECCEEEEEECCCCCHHHHHHHHHCCCCHHEEEECCCCCCCCCCCCEECC
PSGFVGKTMEPFLSGNYTVSDEELYRLLKELADTENIYLEPSALAGMIGPVKVCKEDAYL
CCCCCCCCHHHHHCCCCEECHHHHHHHHHHHCCCCCEEECHHHHHHCCCHHHHHHHHHHH
QEQQLMEKMKKGTHIVWGTGGSMVPEDVMNGYYKTGEALTILEK
HHHHHHHHHHCCCEEEEECCCCCCCHHHHCCCCCCCCEEEEECC
>Mature Secondary Structure
MVRQQFIDFYKNFKPGRGMKEIEKLKEEYPLLNKLIEIEEVFWVNPNMEKYETAIKDSPL
CCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHEEEECCCHHHHHHHHCCCCC
SEENVKDAEERLKRFASYIAKVFPETKDTGGIIESPLVKIPSMKQSLEKNYEQPILGELL
CCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHCCCHHHHHHHHCCCCCHHHHHH
LKCDSHLPISGSIKARGGIYEVLKHAEQLALQQGMLTEEDDYSILDSDTCREFFATYSIA
HHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHEE
VGSTGNLGLSIGIMSAKLGFNVTVHMSADAKQWKKDLLRSKGVNVIEYEADYSKAVEEGR
ECCCCCCEEEEEEEEEECCCEEEEEECCCHHHHHHHHHHHCCCCEEEECCHHHHHHHHHH
RQADADPSCYFVDDENSHDLFLGYAVAASRLQKQLEELEIIVDEEHPLFVYLPCGVGGGP
HHCCCCCCEEEECCCCCCEEEHHHHHHHHHHHHHHHHHEEEECCCCCEEEEEECCCCCCC
GGVAFGLKLLYKDNVHCFFAEPTHSPCMLIGLMTGLHDKIAVQDIGIDNVTDADGLAVGR
CHHHHHHHHEEECCEEEEEECCCCCHHHHHHHHHCCCCHHEEEECCCCCCCCCCCCEECC
PSGFVGKTMEPFLSGNYTVSDEELYRLLKELADTENIYLEPSALAGMIGPVKVCKEDAYL
CCCCCCCCHHHHHCCCCEECHHHHHHHHHHHCCCCCEEECHHHHHHCCCHHHHHHHHHHH
QEQQLMEKMKKGTHIVWGTGGSMVPEDVMNGYYKTGEALTILEK
HHHHHHHHHHCCCEEEEECCCCCCCHHHHCCCCCCCCEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA