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The map label for this gene is yciC [H]

Identifier: 218902927

GI number: 218902927

Start: 1706915

End: 1708102

Strand: Reverse

Name: yciC [H]

Synonym: BCAH820_1810

Alternate gene names: 218902927

Gene position: 1708102-1706915 (Counterclockwise)

Preceding gene: 218902934

Following gene: 218902926

Centisome position: 32.21

GC content: 33.59

Gene sequence:

>1188_bases
ATGAAAAAAATACCTATCACTGTATTAAGTGGGTTTTTAGGATCCGGAAAAACTACATTACTACATCATATTTTAACTAA
TAAGAACAACTTAAAAGTAGCTGTTATCGTTAATGATATGAGCGAAGTAAACATTGATGCCTCCCTTATAAAAAAAGGTG
GTTTTTCACGTACGGAGGAAAAACTAGTAGAAATTCAAAATGGCTGTATTTGTTGTACACTACGAGAAGATTTAATAATA
GAAGTGAATCACCTTGTTGAAAACGGTGATATTGACTATATAGTGATTGAATCTTCCGGTATAAGTGAGCCGATTCCAGT
TGCCCAAACATTTACTTATACTGACGACGTTCTTAACATTGATTTAACGAAAAATTGTCGCCTCGATACGATGGTTACAG
TTGTAGATGCAAATAGATTTTGGGATGATTTTGCAGATGGAGAAAGTTTATTAGATCGCAAACAAGCAATCAATGAAAAT
GATACTCGGGAAGTTATTGATTTATTAATAGATCAAATTGAGTTTGCAAATGTAATTATTCTTAATAAGATAGATTTACT
AGAAAAAGAAGATGTGATAGAACTTCATCAACTGCTACAGAAATTAAATCCTAATGCAAAAATTATTGAATCTTCCTTTA
GCAACGTACCACTGCAAGAAATTTTAAATACAAATGTATTCAATTATGAGGAAGCCAGTCAATCGGCGGGTTGGATACAA
GAATTAAATAGTGAACATCATACACCCGAAACGGAAGAATACGGTATCAATTCCTTTGTATACCGTCGTAAATACCCTTT
CCATCCTGAACGCCTTATGAATTGGCTAGAAAAATGGCCTGTAGATGTCGTAAGAGCAAAAGGCTTTTTCTGGCTCGCAT
CTCGTAATAATATGATAGGTCTTCTGTCTCAAGCAGGTTCCTCTATTACAATTCAAGGAGCCGGTGAATGGATAGCAGCA
TTACCTGAAACTGAAAGAAATCAAATGATCATAGAAGAGCCAGAAGTATTGAAAAACTGGGATAAACAATATGGAGATCG
AATAACTGAACTCGTATTTATTGGAATTGATATGAACCGTTCTTTAATTGAACAATCATTAGATGATTGTCTATTAACAG
AAAAAGAAATGACACAAAACTGGAATACATTCATTGATCCTATTCCAGCTTTTACTTACACTTCATAA

Upstream 100 bases:

>100_bases
ATTCTTAAATCGTAATCATTATGATTTATTATTGATTTTTCCCTTTCAATCATTTAACATAAAACGTAATCATTACGATT
TAAAGGAGAGAAATAATTTC

Downstream 100 bases:

>100_bases
TTCAAAATAGAGAGGCTTCCGTTTACGGAAGCCTTTCTATTTTATCGTTCTCTTATTTAACAAACTTCTTTCATTTGAAT
AATAACTTTACATTAAGTAA

Product: putative cobalamin synthesis protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 395; Mature: 395

Protein sequence:

>395_residues
MKKIPITVLSGFLGSGKTTLLHHILTNKNNLKVAVIVNDMSEVNIDASLIKKGGFSRTEEKLVEIQNGCICCTLREDLII
EVNHLVENGDIDYIVIESSGISEPIPVAQTFTYTDDVLNIDLTKNCRLDTMVTVVDANRFWDDFADGESLLDRKQAINEN
DTREVIDLLIDQIEFANVIILNKIDLLEKEDVIELHQLLQKLNPNAKIIESSFSNVPLQEILNTNVFNYEEASQSAGWIQ
ELNSEHHTPETEEYGINSFVYRRKYPFHPERLMNWLEKWPVDVVRAKGFFWLASRNNMIGLLSQAGSSITIQGAGEWIAA
LPETERNQMIIEEPEVLKNWDKQYGDRITELVFIGIDMNRSLIEQSLDDCLLTEKEMTQNWNTFIDPIPAFTYTS

Sequences:

>Translated_395_residues
MKKIPITVLSGFLGSGKTTLLHHILTNKNNLKVAVIVNDMSEVNIDASLIKKGGFSRTEEKLVEIQNGCICCTLREDLII
EVNHLVENGDIDYIVIESSGISEPIPVAQTFTYTDDVLNIDLTKNCRLDTMVTVVDANRFWDDFADGESLLDRKQAINEN
DTREVIDLLIDQIEFANVIILNKIDLLEKEDVIELHQLLQKLNPNAKIIESSFSNVPLQEILNTNVFNYEEASQSAGWIQ
ELNSEHHTPETEEYGINSFVYRRKYPFHPERLMNWLEKWPVDVVRAKGFFWLASRNNMIGLLSQAGSSITIQGAGEWIAA
LPETERNQMIIEEPEVLKNWDKQYGDRITELVFIGIDMNRSLIEQSLDDCLLTEKEMTQNWNTFIDPIPAFTYTS
>Mature_395_residues
MKKIPITVLSGFLGSGKTTLLHHILTNKNNLKVAVIVNDMSEVNIDASLIKKGGFSRTEEKLVEIQNGCICCTLREDLII
EVNHLVENGDIDYIVIESSGISEPIPVAQTFTYTDDVLNIDLTKNCRLDTMVTVVDANRFWDDFADGESLLDRKQAINEN
DTREVIDLLIDQIEFANVIILNKIDLLEKEDVIELHQLLQKLNPNAKIIESSFSNVPLQEILNTNVFNYEEASQSAGWIQ
ELNSEHHTPETEEYGINSFVYRRKYPFHPERLMNWLEKWPVDVVRAKGFFWLASRNNMIGLLSQAGSSITIQGAGEWIAA
LPETERNQMIIEEPEVLKNWDKQYGDRITELVFIGIDMNRSLIEQSLDDCLLTEKEMTQNWNTFIDPIPAFTYTS

Specific function: May bind GTP. Might act as metal chaperone (Potential). Contributes to optimal growth under starvation for zinc [H]

COG id: COG0523

COG function: function code R; Putative GTPases (G3E family)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 cobW C-terminal domain [H]

Homologues:

Organism=Homo sapiens, GI33469141, Length=260, Percent_Identity=31.5384615384615, Blast_Score=123, Evalue=2e-28,
Organism=Homo sapiens, GI126722884, Length=260, Percent_Identity=31.1538461538462, Blast_Score=121, Evalue=1e-27,
Organism=Homo sapiens, GI146231952, Length=260, Percent_Identity=31.1538461538462, Blast_Score=118, Evalue=9e-27,
Organism=Homo sapiens, GI148727351, Length=260, Percent_Identity=30.7692307692308, Blast_Score=117, Evalue=1e-26,
Organism=Homo sapiens, GI223941779, Length=227, Percent_Identity=32.15859030837, Blast_Score=114, Evalue=2e-25,
Organism=Homo sapiens, GI223941776, Length=249, Percent_Identity=30.1204819277108, Blast_Score=105, Evalue=1e-22,
Organism=Homo sapiens, GI119120938, Length=138, Percent_Identity=36.9565217391304, Blast_Score=91, Evalue=2e-18,
Organism=Escherichia coli, GI87082430, Length=369, Percent_Identity=27.6422764227642, Blast_Score=110, Evalue=1e-25,
Organism=Escherichia coli, GI1788499, Length=341, Percent_Identity=26.3929618768328, Blast_Score=87, Evalue=2e-18,
Organism=Saccharomyces cerevisiae, GI6324356, Length=235, Percent_Identity=30.6382978723404, Blast_Score=110, Evalue=3e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003495
- InterPro:   IPR011629 [H]

Pfam domain/function: PF02492 cobW; PF07683 CobW_C [H]

EC number: NA

Molecular weight: Translated: 45097; Mature: 45097

Theoretical pI: Translated: 4.30; Mature: 4.30

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKIPITVLSGFLGSGKTTLLHHILTNKNNLKVAVIVNDMSEVNIDASLIKKGGFSRTEE
CCCCCHHHHHHHCCCCHHHHHHHHHCCCCCEEEEEEEECCCCCCCCHHHHHCCCCCHHHH
KLVEIQNGCICCTLREDLIIEVNHLVENGDIDYIVIESSGISEPIPVAQTFTYTDDVLNI
HHHHHCCCEEEEEECCCEEEEEEHHHCCCCCCEEEEECCCCCCCCCCCEEEEECCCEEEE
DLTKNCRLDTMVTVVDANRFWDDFADGESLLDRKQAINENDTREVIDLLIDQIEFANVII
EECCCCCCCEEEEEEECHHHHHHHCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCEEE
LNKIDLLEKEDVIELHQLLQKLNPNAKIIESSFSNVPLQEILNTNVFNYEEASQSAGWIQ
EECCCCCCCCHHHHHHHHHHHHCCCCEEECCCCCCCCHHHHHCCCCCCCHHHHHHHHHHH
ELNSEHHTPETEEYGINSFVYRRKYPFHPERLMNWLEKWPVDVVRAKGFFWLASRNNMIG
HHCCCCCCCCCHHCCCCCEEEECCCCCCHHHHHHHHHHCCHHHEEECCEEEEECCCCEEE
LLSQAGSSITIQGAGEWIAALPETERNQMIIEEPEVLKNWDKQYGDRITELVFIGIDMNR
EHCCCCCEEEEEECCCEEEECCCCCCCCEEECCCHHHHHHHHHHHHHEEEEEEEEECCCH
SLIEQSLDDCLLTEKEMTQNWNTFIDPIPAFTYTS
HHHHHHHHHHHCCHHHHHCCCCHHCCCCCCCCCCC
>Mature Secondary Structure
MKKIPITVLSGFLGSGKTTLLHHILTNKNNLKVAVIVNDMSEVNIDASLIKKGGFSRTEE
CCCCCHHHHHHHCCCCHHHHHHHHHCCCCCEEEEEEEECCCCCCCCHHHHHCCCCCHHHH
KLVEIQNGCICCTLREDLIIEVNHLVENGDIDYIVIESSGISEPIPVAQTFTYTDDVLNI
HHHHHCCCEEEEEECCCEEEEEEHHHCCCCCCEEEEECCCCCCCCCCCEEEEECCCEEEE
DLTKNCRLDTMVTVVDANRFWDDFADGESLLDRKQAINENDTREVIDLLIDQIEFANVII
EECCCCCCCEEEEEEECHHHHHHHCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCEEE
LNKIDLLEKEDVIELHQLLQKLNPNAKIIESSFSNVPLQEILNTNVFNYEEASQSAGWIQ
EECCCCCCCCHHHHHHHHHHHHCCCCEEECCCCCCCCHHHHHCCCCCCCHHHHHHHHHHH
ELNSEHHTPETEEYGINSFVYRRKYPFHPERLMNWLEKWPVDVVRAKGFFWLASRNNMIG
HHCCCCCCCCCHHCCCCCEEEECCCCCCHHHHHHHHHHCCHHHEEECCEEEEECCCCEEE
LLSQAGSSITIQGAGEWIAALPETERNQMIIEEPEVLKNWDKQYGDRITELVFIGIDMNR
EHCCCCCEEEEEECCCEEEECCCCCCCCEEECCCHHHHHHHHHHHHHEEEEEEEEECCCH
SLIEQSLDDCLLTEKEMTQNWNTFIDPIPAFTYTS
HHHHHHHHHHHCCHHHHHCCCCHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8969502; 9384377; 9811636 [H]