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The map label for this gene is yfiS [H]

Identifier: 218902836

GI number: 218902836

Start: 1630917

End: 1632131

Strand: Reverse

Name: yfiS [H]

Synonym: BCAH820_1719

Alternate gene names: 218902836

Gene position: 1632131-1630917 (Counterclockwise)

Preceding gene: 218902837

Following gene: 218902835

Centisome position: 30.78

GC content: 32.84

Gene sequence:

>1215_bases
ATGTCAGTTTCTTATTCCGCACTTCTTAAAACAAATAAAAACTTCAACAAACTATTTTACGGACAAACATTAAGTGTACT
TGGAGATTGGTTTCATACAGTAGCTTTATTAACATTCGTCTATAGCATAACAGAATCTCCGTTTATGATTGCACTTACTT
TTATAAGTAAAGGTTTACCACAACTACTTCTTAGCCCTTTCATAGGCGGAGTGGTAGATCGTTTTTCTAAAAAGAATATT
ATGATTTTCACCGATATTATACGGGGAATTCTAGTCCTTACATACATACTCGCAAGCTATAAAATTGAAATTATTTTCAT
TGCTAATATATGTTTATCTGTACTTTCTTGCTTATTTGAGCCAGCTAAACAAGCAACCTTAAAAAACATCGTACACGAAA
ATCATTTCGTAACTGCTAACTCTCTTTCTAGTACAATGAATGGTTTTATGTCTATTATGGGTGCTTCTTTAGGCGGTATA
ATTGCACAATCTTTACATATTGAGTTCGCTTTTTTAGTAAATAGCCTATCATACTTTATTTCAGCCTATTTTATTTATAG
TATGTGTATCCCTTCTCATAATACTTGTAACAAGAAAAAAGCATTTTTGACTGATATAAAAGATGGTTATACATATATAT
CGCAAACAAAAATCATTTTAACATTAATTGTTGTCGGCATTTCATGGGGGCTTATTGGCGGCGCTTATCAGCTACTTCTA
ACAATCTATGCCGAAAAAATTTTCCACACGAACATTGGGATTTTATATACGGTTCAAGGGGCTGGGCTTATGATAGGAAG
CTTTCTCGTTAATCTTTATATATCCCATAATAAAGAAAAAATGAAAAAAGCATTTGGCTGGGCCTACTTCCTACAAGGCA
TTTTCTTTCTTGGATTCATTCTATCCGATCAACTTATTTTCGGTATCATTACATTACTATGTATGCGCATAGCAGGAGGA
ATCATCGTTCCACTTGATACGACATTACTTCAAACTTACACGCGGGAAAATATGATTGGTAAAGTTTTCTCCTTTCATTA
CTCTATTTATGGCTCACTTATACAGTTATCTATGCTCATGACAGGATGGTTATTAGAAATCCTTTCTCCTCAAATGATTG
GTAGTTTATTAGCTACATGCTGTATATTTGTAAGTTTTATATGGCTTTATCTGTTTTATCGCGGGAAACTTAGTGAAGAA
TCTACTATTACTTAA

Upstream 100 bases:

>100_bases
GCACAATTACCAGTTGGACTTCCTTCAGAAAAGAAAGTGTATTTAAGTGAATGGAAAAAACAAATTCAAGCATCATCATT
ACATAAGGATTGAGCTTTTT

Downstream 100 bases:

>100_bases
TAGCATGTTTATGTACATGCTATTTTTATTTATGTCGAAATACAGAGGAAAAAGGCGATTTATTTTCCTTACGTTCTATT
TTTTTAGAATGTACAATAAA

Product: putative permease

Products: Proton [Cytoplasm]; drug [Periplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 404; Mature: 403

Protein sequence:

>404_residues
MSVSYSALLKTNKNFNKLFYGQTLSVLGDWFHTVALLTFVYSITESPFMIALTFISKGLPQLLLSPFIGGVVDRFSKKNI
MIFTDIIRGILVLTYILASYKIEIIFIANICLSVLSCLFEPAKQATLKNIVHENHFVTANSLSSTMNGFMSIMGASLGGI
IAQSLHIEFAFLVNSLSYFISAYFIYSMCIPSHNTCNKKKAFLTDIKDGYTYISQTKIILTLIVVGISWGLIGGAYQLLL
TIYAEKIFHTNIGILYTVQGAGLMIGSFLVNLYISHNKEKMKKAFGWAYFLQGIFFLGFILSDQLIFGIITLLCMRIAGG
IIVPLDTTLLQTYTRENMIGKVFSFHYSIYGSLIQLSMLMTGWLLEILSPQMIGSLLATCCIFVSFIWLYLFYRGKLSEE
STIT

Sequences:

>Translated_404_residues
MSVSYSALLKTNKNFNKLFYGQTLSVLGDWFHTVALLTFVYSITESPFMIALTFISKGLPQLLLSPFIGGVVDRFSKKNI
MIFTDIIRGILVLTYILASYKIEIIFIANICLSVLSCLFEPAKQATLKNIVHENHFVTANSLSSTMNGFMSIMGASLGGI
IAQSLHIEFAFLVNSLSYFISAYFIYSMCIPSHNTCNKKKAFLTDIKDGYTYISQTKIILTLIVVGISWGLIGGAYQLLL
TIYAEKIFHTNIGILYTVQGAGLMIGSFLVNLYISHNKEKMKKAFGWAYFLQGIFFLGFILSDQLIFGIITLLCMRIAGG
IIVPLDTTLLQTYTRENMIGKVFSFHYSIYGSLIQLSMLMTGWLLEILSPQMIGSLLATCCIFVSFIWLYLFYRGKLSEE
STIT
>Mature_403_residues
SVSYSALLKTNKNFNKLFYGQTLSVLGDWFHTVALLTFVYSITESPFMIALTFISKGLPQLLLSPFIGGVVDRFSKKNIM
IFTDIIRGILVLTYILASYKIEIIFIANICLSVLSCLFEPAKQATLKNIVHENHFVTANSLSSTMNGFMSIMGASLGGII
AQSLHIEFAFLVNSLSYFISAYFIYSMCIPSHNTCNKKKAFLTDIKDGYTYISQTKIILTLIVVGISWGLIGGAYQLLLT
IYAEKIFHTNIGILYTVQGAGLMIGSFLVNLYISHNKEKMKKAFGWAYFLQGIFFLGFILSDQLIFGIITLLCMRIAGGI
IVPLDTTLLQTYTRENMIGKVFSFHYSIYGSLIQLSMLMTGWLLEILSPQMIGSLLATCCIFVSFIWLYLFYRGKLSEES
TIT

Specific function: Unknown

COG id: COG0477

COG function: function code GEPR; Permeases of the major facilitator superfamily

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. TCR/tet family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 45252; Mature: 45120

Theoretical pI: Translated: 9.03; Mature: 9.03

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure 
SVSYSALLKTNKNFNKLFYGQTLSVLGDWFHTVALLTFVYSITESPFMIALTFISKGLP
CCCHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCHH
QLLLSPFIGGVVDRFSKKNIMIFTDIIRGILVLTYILASYKIEIIFIANICLSVLSCLFE
HHHHHHHHHHHHHHHCCCCEEEHHHHHHHHHHHHHHHHHHHEEEEEHHHHHHHHHHHHHH
PAKQATLKNIVHENHFVTANSLSSTMNGFMSIMGASLGGIIAQSLHIEFAFLVNSLSYFI
HHHHHHHHHHHHCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SAYFIYSMCIPSHNTCNKKKAFLTDIKDGYTYISQTKIILTLIVVGISWGLIGGAYQLLL
HHHHHHHHHCCCCCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TIYAEKIFHTNIGILYTVQGAGLMIGSFLVNLYISHNKEKMKKAFGWAYFLQGIFFLGFI
HHHHHHHHHCCCCEEEEECCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHH
LSDQLIFGIITLLCMRIAGGIIVPLDTTLLQTYTRENMIGKVFSFHYSIYGSLIQLSMLM
HHHHHHHHHHHHHHHHHHCCEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TGWLLEILSPQMIGSLLATCCIFVSFIWLYLFYRGKLSEESTIT
HHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; drug [Cytoplasm] [C]

Specific reaction: Proton [Periplasm] + drug [Cytoplasm] = Proton [Cytoplasm] + drug [Periplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8946165; 9384377 [H]