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The map label for this gene is ppnK [H]

Identifier: 218902401

GI number: 218902401

Start: 1225843

End: 1226640

Strand: Direct

Name: ppnK [H]

Synonym: BCAH820_1283

Alternate gene names: 218902401

Gene position: 1225843-1226640 (Clockwise)

Preceding gene: 218902400

Following gene: 218902402

Centisome position: 23.12

GC content: 39.85

Gene sequence:

>798_bases
ATGAAATTTACAATTATGTCAAAGGGAGATCAATCATCAGATACACTGGCAAGCACGATGAAAGAATACTTGCTAGATTT
CGGATTTATAATGGATGAAAAGGAACCCGATATTGTAATTTCTGTTGGGGGAGATGGAACGCTTTTATATGCATTTCATC
GTTATTATGATCGATTGGCTGAAACGGCATTTGTTGGTGTACATACAGGGCATTTAGGTTTCTATGCAGATTGGTTACCG
ACAGAAGTAGAGAAATTAGTAATTGCAATTGCTAAAACACCATTCCAAGTGGTGGAATATCCGCTTTTAGAAGTGATTAT
TCGCTATGTGAATGGGAGTAAAGAGTCGCAGTATTTAGCGATGAATGAAGCGACTGTAAAAAGTGCAGAAGGTACATTAG
TAACAGAAGTGGAAATACGCGGAGAGTACTTTGAAACGTTCCGTGGTGATGGCCTTTGTATTTCTACTCCTTCGGGAAGT
ACTGCGTATAATAAGGCGCTTGGTGGAGCAATTATTCACCCTTCTATTGAAGCGATTCAAATTGCAGAAATGGCATCTAT
TAATAACCGTGTGTTTCGTACGGTAGGTTCGCCTCTCGTACTGCCGAAACATCATACATGTGTATTGAAGCCAGCTGCAG
GAATGAACTTACAAATTACGGTGGACCATTTAACAATGGTTCATCAAGATGTGAAATCAATTCAGTATCGCGTTGCAAAT
GAAAAAGTACGATTTGTTCGTTTCCGTCCATTCCCGTTCTGGAAACGGGTTCGTGACTCGTTTGTTGCAGATAAATAG

Upstream 100 bases:

>100_bases
AATGTCTTCTATTCGTCTTGAAATTCAAGAAGCACAGAAAGCTTTTTCAAGAAAGCAAGAAACGAAAGATTCTGAATCAT
AAACTAAAGGGTGTTGGGCG

Downstream 100 bases:

>100_bases
AAAGGGTTTATATATTTGAACAGATTTACATTGAAATGGGATATAGAATCGGCTGAAGAAGGAACTTTAGTTAGAGAATT
TTTAAAAACAAAAGGGATCT

Product: inorganic polyphosphate/ATP-NAD kinase

Products: NA

Alternate protein names: Poly(P)/ATP NAD kinase 1 [H]

Number of amino acids: Translated: 265; Mature: 265

Protein sequence:

>265_residues
MKFTIMSKGDQSSDTLASTMKEYLLDFGFIMDEKEPDIVISVGGDGTLLYAFHRYYDRLAETAFVGVHTGHLGFYADWLP
TEVEKLVIAIAKTPFQVVEYPLLEVIIRYVNGSKESQYLAMNEATVKSAEGTLVTEVEIRGEYFETFRGDGLCISTPSGS
TAYNKALGGAIIHPSIEAIQIAEMASINNRVFRTVGSPLVLPKHHTCVLKPAAGMNLQITVDHLTMVHQDVKSIQYRVAN
EKVRFVRFRPFPFWKRVRDSFVADK

Sequences:

>Translated_265_residues
MKFTIMSKGDQSSDTLASTMKEYLLDFGFIMDEKEPDIVISVGGDGTLLYAFHRYYDRLAETAFVGVHTGHLGFYADWLP
TEVEKLVIAIAKTPFQVVEYPLLEVIIRYVNGSKESQYLAMNEATVKSAEGTLVTEVEIRGEYFETFRGDGLCISTPSGS
TAYNKALGGAIIHPSIEAIQIAEMASINNRVFRTVGSPLVLPKHHTCVLKPAAGMNLQITVDHLTMVHQDVKSIQYRVAN
EKVRFVRFRPFPFWKRVRDSFVADK
>Mature_265_residues
MKFTIMSKGDQSSDTLASTMKEYLLDFGFIMDEKEPDIVISVGGDGTLLYAFHRYYDRLAETAFVGVHTGHLGFYADWLP
TEVEKLVIAIAKTPFQVVEYPLLEVIIRYVNGSKESQYLAMNEATVKSAEGTLVTEVEIRGEYFETFRGDGLCISTPSGS
TAYNKALGGAIIHPSIEAIQIAEMASINNRVFRTVGSPLVLPKHHTCVLKPAAGMNLQITVDHLTMVHQDVKSIQYRVAN
EKVRFVRFRPFPFWKRVRDSFVADK

Specific function: Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus [H]

COG id: COG0061

COG function: function code G; Predicted sugar kinase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NAD kinase family [H]

Homologues:

Organism=Escherichia coli, GI1788968, Length=153, Percent_Identity=31.3725490196078, Blast_Score=68, Evalue=5e-13,
Organism=Saccharomyces cerevisiae, GI6325068, Length=238, Percent_Identity=22.2689075630252, Blast_Score=64, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016064
- InterPro:   IPR017438
- InterPro:   IPR017437
- InterPro:   IPR002504 [H]

Pfam domain/function: PF01513 NAD_kinase [H]

EC number: =2.7.1.23 [H]

Molecular weight: Translated: 29724; Mature: 29724

Theoretical pI: Translated: 6.72; Mature: 6.72

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKFTIMSKGDQSSDTLASTMKEYLLDFGFIMDEKEPDIVISVGGDGTLLYAFHRYYDRLA
CEEEEECCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCEEEHHHHHHHHHHH
ETAFVGVHTGHLGFYADWLPTEVEKLVIAIAKTPFQVVEYPLLEVIIRYVNGSKESQYLA
HHEEEEEEECCCCEEECCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCEEEE
MNEATVKSAEGTLVTEVEIRGEYFETFRGDGLCISTPSGSTAYNKALGGAIIHPSIEAIQ
ECCHHHCCCCCCEEEEEEECCHHHHHHCCCCEEEECCCCCCHHHHHCCCEEECCCHHHHH
IAEMASINNRVFRTVGSPLVLPKHHTCVLKPAAGMNLQITVDHLTMVHQDVKSIQYRVAN
HHHHHHHHHHHHHHCCCCEECCCCCEEEEECCCCCEEEEEHHHHHHHHHHHHHHHHHHCC
EKVRFVRFRPFPFWKRVRDSFVADK
CEEEEEEECCCHHHHHHHHHHCCCC
>Mature Secondary Structure
MKFTIMSKGDQSSDTLASTMKEYLLDFGFIMDEKEPDIVISVGGDGTLLYAFHRYYDRLA
CEEEEECCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCEEEHHHHHHHHHHH
ETAFVGVHTGHLGFYADWLPTEVEKLVIAIAKTPFQVVEYPLLEVIIRYVNGSKESQYLA
HHEEEEEEECCCCEEECCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCEEEE
MNEATVKSAEGTLVTEVEIRGEYFETFRGDGLCISTPSGSTAYNKALGGAIIHPSIEAIQ
ECCHHHCCCCCCEEEEEEECCHHHHHHCCCCEEEECCCCCCHHHHHCCCEEECCCHHHHH
IAEMASINNRVFRTVGSPLVLPKHHTCVLKPAAGMNLQITVDHLTMVHQDVKSIQYRVAN
HHHHHHHHHHHHHHCCCCEECCCCCEEEEECCCCCEEEEEHHHHHHHHHHHHHHHHHHCC
EKVRFVRFRPFPFWKRVRDSFVADK
CEEEEEEECCCHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12721629 [H]