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The map label for this gene is hlgB [H]

Identifier: 218902306

GI number: 218902306

Start: 1138459

End: 1139472

Strand: Reverse

Name: hlgB [H]

Synonym: BCAH820_1188

Alternate gene names: 218902306

Gene position: 1139472-1138459 (Counterclockwise)

Preceding gene: 218902308

Following gene: 218902283

Centisome position: 21.49

GC content: 36.98

Gene sequence:

>1014_bases
ATGAAACGCTCTAAAACGTATTTAAAATGTTTAGCATTATCCGCTGTTTTTGCTAGTAGCGCTTTAGCACTTTCAACACC
TGCTGCTTACGCTCAAACGACGTCACAAGTTGTAACAGATATCGGGCAAAATGCAAAAACACATACGAGCTATAATACAT
TTAATAATGATCAAACTGATAATATGACAATGTCTTTAAAGGTAACTTTTATCGATGATCCAAGCGCTGATAAACAGATT
GCCGTTATTAATACAACTGGTAGTTTTCTAAAAGCAAATCCTACTATAAGTAGTGCACCTATTGATAACTACCCAATCCC
TGGCGCTAGTGCAACATTACGCTATCCTTCACAATATGATATTGCCTTTAATCTTCAAGATAACAGCGCCCGTTTCTTTA
ACGTAGCACCTACAAATGCTGTAGAAGAAACGACTGTAACCTCTAGTGTATCTTATCAACTTGGCGGTTCTGTTAAAGCT
TCTGCAACGCCAAATGGACCTAGCGCTGAAGCCGGTGCAACTGGCCAAGTAACTTGGTCTGATTCTGTAAGCTATAAACA
AACTAGCTATAAAACAAACTTAATTGACCAAACAAATAAAAACGTAAAATGGAACGTATTCTTTAACGGATATAACAATC
AAAACTGGGGTATTTACACACGTGATTCCTACCATTCTTTATATGGAAACCAACTGTTCATGTACTCTCGCACATACTTA
TATGAATCTGATGCAAAAGGTAATTTAATACCGATGGATCAACTTCCAGCGCTAACAAATAGTGGTTTCTCTCCTGGTAT
GATCGCTGTTGTTATCTCTGAAAAAAATACAGACCAATCTAACCTACAAGTCGCTTATACAAAACATGCCGACGACTACC
AACTTCGTCCAGGCTACACATTCGGAACTGCAAACTGGGTTGGAAACAACGTAAAAGATGTTGATCAAAAAACATTTAAT
AAGTTGTTCACACTGGATTGGAAGAATAAGAAATTAGTAGAGAAAAATAGATAA

Upstream 100 bases:

>100_bases
ACCTATGCAATTATGCATAACTATCCCTTCCGTTTTATTTTCATGTTACGATATAAATGAAATACGACATATATCGACAA
AAATAAAAGGAAGTGATTGT

Downstream 100 bases:

>100_bases
AGAAAACCGAACCGCCATTTAGATGGGGGTTCGGTTTTTATTTAAATTACAAACTCTTTCACTTCACATTAAAATAAAAC
TTTCAATACTACAGAACAAA

Product: cytotoxin K

Products: NA

Alternate protein names: H-gamma-1; H-gamma-I [H]

Number of amino acids: Translated: 337; Mature: 337

Protein sequence:

>337_residues
MKRSKTYLKCLALSAVFASSALALSTPAAYAQTTSQVVTDIGQNAKTHTSYNTFNNDQTDNMTMSLKVTFIDDPSADKQI
AVINTTGSFLKANPTISSAPIDNYPIPGASATLRYPSQYDIAFNLQDNSARFFNVAPTNAVEETTVTSSVSYQLGGSVKA
SATPNGPSAEAGATGQVTWSDSVSYKQTSYKTNLIDQTNKNVKWNVFFNGYNNQNWGIYTRDSYHSLYGNQLFMYSRTYL
YESDAKGNLIPMDQLPALTNSGFSPGMIAVVISEKNTDQSNLQVAYTKHADDYQLRPGYTFGTANWVGNNVKDVDQKTFN
KLFTLDWKNKKLVEKNR

Sequences:

>Translated_337_residues
MKRSKTYLKCLALSAVFASSALALSTPAAYAQTTSQVVTDIGQNAKTHTSYNTFNNDQTDNMTMSLKVTFIDDPSADKQI
AVINTTGSFLKANPTISSAPIDNYPIPGASATLRYPSQYDIAFNLQDNSARFFNVAPTNAVEETTVTSSVSYQLGGSVKA
SATPNGPSAEAGATGQVTWSDSVSYKQTSYKTNLIDQTNKNVKWNVFFNGYNNQNWGIYTRDSYHSLYGNQLFMYSRTYL
YESDAKGNLIPMDQLPALTNSGFSPGMIAVVISEKNTDQSNLQVAYTKHADDYQLRPGYTFGTANWVGNNVKDVDQKTFN
KLFTLDWKNKKLVEKNR
>Mature_337_residues
MKRSKTYLKCLALSAVFASSALALSTPAAYAQTTSQVVTDIGQNAKTHTSYNTFNNDQTDNMTMSLKVTFIDDPSADKQI
AVINTTGSFLKANPTISSAPIDNYPIPGASATLRYPSQYDIAFNLQDNSARFFNVAPTNAVEETTVTSSVSYQLGGSVKA
SATPNGPSAEAGATGQVTWSDSVSYKQTSYKTNLIDQTNKNVKWNVFFNGYNNQNWGIYTRDSYHSLYGNQLFMYSRTYL
YESDAKGNLIPMDQLPALTNSGFSPGMIAVVISEKNTDQSNLQVAYTKHADDYQLRPGYTFGTANWVGNNVKDVDQKTFN
KLFTLDWKNKKLVEKNR

Specific function: Toxin that seems to act by forming pores in the membrane of the cell. Has a hemolytic and a leucotoxic activity [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aerolysin family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003963
- InterPro:   IPR001340
- InterPro:   IPR016183 [H]

Pfam domain/function: PF07968 Leukocidin [H]

EC number: NA

Molecular weight: Translated: 37174; Mature: 37174

Theoretical pI: Translated: 8.95; Mature: 8.95

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKRSKTYLKCLALSAVFASSALALSTPAAYAQTTSQVVTDIGQNAKTHTSYNTFNNDQTD
CCCCHHHHHHHHHHHHHHCCCEEECCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCC
NMTMSLKVTFIDDPSADKQIAVINTTGSFLKANPTISSAPIDNYPIPGASATLRYPSQYD
CEEEEEEEEEECCCCCCCEEEEEECCCCEEEECCCCCCCCCCCCCCCCCCEEEECCCEEE
IAFNLQDNSARFFNVAPTNAVEETTVTSSVSYQLGGSVKASATPNGPSAEAGATGQVTWS
EEEEEECCCCEEEEECCCCCCCCCEEEEEEEEEECCCEEECCCCCCCCCCCCCCEEEEEC
DSVSYKQTSYKTNLIDQTNKNVKWNVFFNGYNNQNWGIYTRDSYHSLYGNQLFMYSRTYL
CCCCEEECCEEECCCCCCCCCEEEEEEECCCCCCCCEEEECCCHHHHCCCEEEEEEEEEE
YESDAKGNLIPMDQLPALTNSGFSPGMIAVVISEKNTDQSNLQVAYTKHADDYQLRPGYT
EECCCCCCEEEHHHCCHHHCCCCCCCEEEEEEECCCCCCCCEEEEEEECCCCEEECCCEE
FGTANWVGNNVKDVDQKTFNKLFTLDWKNKKLVEKNR
ECCHHHCCCCHHHHHHHHHHHEEEEECCCCCCCCCCC
>Mature Secondary Structure
MKRSKTYLKCLALSAVFASSALALSTPAAYAQTTSQVVTDIGQNAKTHTSYNTFNNDQTD
CCCCHHHHHHHHHHHHHHCCCEEECCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCC
NMTMSLKVTFIDDPSADKQIAVINTTGSFLKANPTISSAPIDNYPIPGASATLRYPSQYD
CEEEEEEEEEECCCCCCCEEEEEECCCCEEEECCCCCCCCCCCCCCCCCCEEEECCCEEE
IAFNLQDNSARFFNVAPTNAVEETTVTSSVSYQLGGSVKASATPNGPSAEAGATGQVTWS
EEEEEECCCCEEEEECCCCCCCCCEEEEEEEEEECCCEEECCCCCCCCCCCCCCEEEEEC
DSVSYKQTSYKTNLIDQTNKNVKWNVFFNGYNNQNWGIYTRDSYHSLYGNQLFMYSRTYL
CCCCEEECCEEECCCCCCCCCEEEEEEECCCCCCCCEEEECCCHHHHCCCEEEEEEEEEE
YESDAKGNLIPMDQLPALTNSGFSPGMIAVVISEKNTDQSNLQVAYTKHADDYQLRPGYT
EECCCCCCEEEHHHCCHHHCCCCCCCEEEEEEECCCCCCCCEEEEEEECCCCEEECCCEE
FGTANWVGNNVKDVDQKTFNKLFTLDWKNKKLVEKNR
ECCHHHCCCCHHHHHHHHHHHEEEEECCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA