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The map label for this gene is helD [H]

Identifier: 218902236

GI number: 218902236

Start: 1069750

End: 1072080

Strand: Reverse

Name: helD [H]

Synonym: BCAH820_1118

Alternate gene names: 218902236

Gene position: 1072080-1069750 (Counterclockwise)

Preceding gene: 218902237

Following gene: 218902235

Centisome position: 20.22

GC content: 39.25

Gene sequence:

>2331_bases
ATGAACAAAAAACTTGATCAAGAGCAAAAACGATTGGATACCGTAATCGAAACGATTACGCAGCAAATTGATAAGCTGGA
AAACGAAACTGGCAGACGCCGAGCAGAAGTAATCAATATTCGTAAACATTTCTGGGATGACGTGAAAGTGAATACTGATA
CTTTTGATGATTATCTTGAAACAGTTATCAACTTAAGACAACAAGCTCAGTCACTAGCTGTCACACAAATTACTCATAAG
CACACCTTTAATCGACTTGCCGCATTAAGACGCATGCATAAAGCACCTTATTTTGGACGAATTGATTTCAAAGAAGAAGG
AGAATCTGCTGCGGAGAAAATTTATATTGGCGTAGCTACACTTACTGATGCGAGCGGAGAAAACTTTCTTATATATGACT
GGCGCGCACCCATTTCGAGTGTCTACTACGATTATCCACCAGGACCGGCTGAATACAGTACACCAGGTGGCGTAATTCAC
GGTAATGTGGAGAAAAAATTACAATACATTATTCAAAATGGCGAGATTGATTCTATGTTCGATACGAGCCTTACAATTGG
CGATGAAATCTTGCAACAAGCGCTCGGAAAAGGCACAAACAAACATATGCAAAGTATCGTTGCTACGATTCAGCGCGAGC
AAAATGAAATTATTCGTCACGATGAAGGCCGACTCCTTATCGTACAAGGAGCTGCTGGTAGCGGTAAAACGTCAGCCGCC
CTGCAACGAATCGCCTACTTACTATATAAATATCGCGAATGGTTAAAAGCGGATCAAATTATTCTCTTCTCCCCTAACTC
TATGTTCAACAGCTACGTTTCTAACGTACTACCTGAACTTGGTGAAGAGAATATGCAGCAAGTTACATTCCAAGAATATT
TAAACCATAGACTAAGTAAATCATTTGACGTGGAAGACCCTTATGAACAATTAGAGTATATGCTAACTGAAACGAATAGT
CCTACCTATAAAACGAGAAATGCTAGTATTCGTTTTAAAGCATCTACTCAATTTTTCGAGATGATTCGAGCGTACAGACA
ATCTCTTGAATCTTCAGGCATGCTATTTAGAGGAATGAAATTTAGAGGAAAACTGATTGTTTCTGCGAAAGAAATTACAG
AGCAATTTTACAATACCGACTTCTCCCTTCGCTTCCATAATCGAATTGAAAAGTTAACAGATTGGCTAAATAAACAAATA
GATGCAATTGAAAAAGCAGAATTGAAAAAGCCTTGGGTAGAAGAAGAAATTGAATTACTTAGTAAAGATGAATACCAAAA
GGCTTATAAATACTTGCAGAAAAAAGGCGAGTTTGACGACAACTCCTTTCAAGATTTTGAGAAAGAAACGAGAGTACTTG
GACGTATGATTGTCCGTAAAAAATTGAAGCCGCTGCGTAAAGGCGTTCAAACATTACGCTTTATCAATTTCACAGGTATA
TATAAACAACTTTTCACAGATGCATCATGGGGGACTGGAGAAAAACCGAAAGAATGGGATGACATTTGCTCACTAACGGT
GAACATGCTCGATGAAGGAAAGCTATATTACGAGGATGCGACTCCATTTTTACTTTTAAAAGAGTTAATTGAAGGTTTCC
AAACGAACAGATCGATTAAACACGTACTCGTAGACGAAGCACAAGATTATTCGCCGTTTCAGTTCGAGTTTTTAAAACGT
CTCTTCCCTGCCGCAAGAATGACGGTACTTGGAGACTTTAACCAAGCAATATTTGCTCATGCGAGTGAAACAGTTAATTT
CGATACACTTACGAATTTATACGGGCCAGACGAAACGAACGGCATTAACTTAACTCGTAGTTATCGCTCAACAAAACCAA
TCATTGAATTTACACGTGCTCTCGTACCGGAAGGCAACAACATTCACGCCTTTGAACGTGACGGTGAGAAACCTACAGTG
ACGAAAGTAGCGAATGAGAGCGAACTGCACGAACGTATTACTGCCAAAGTTGCTGAATTACAAAAACAAAATCACAACAC
GATCGCAATTATATGTAAATCTGCAGCTGAAAGCGCCGCTGCCTATGAGGCACTTAGTAGCATTGAAGATATTAAACTTG
TGAAGAGCACCTCTGCTGAATACGAACAAGGCGTTGTTATTATCCCTGCTTACTTAGCGAAAGGTATCGAATTTGATGCT
GTTATTATTTACGATGCTTCTAAAGATGTGTACAGTGATGAGAGCGTTCGTAGATTGTTCTATACTGCTTGTACGCGCGC
GATGCATGAATTACAACTTTATAGCGTTGGCGAGGTTAGCCCTTTTATTATTGAGGCTGATTCGGAGAGTTTTGAACTTA
TTACACCTTGA

Upstream 100 bases:

>100_bases
TTTCTAAAATTAAAAGAACGTATTTATCCGTATCTTAATTGTACACCAAAACACATCTTCAGTCAACCTCTATTTTTCAC
TTTTAAAGGAGTGCTATCGT

Downstream 100 bases:

>100_bases
TAACAATCAAGGTGTTTCTTTTTTGTGCAGGATTTACAACTTTAAAGTAGAATATATCAGTTTAGAAAAAAGTTAAGGAG
CGAAAAGATGAACCATTATT

Product: helicase, UvrD/Rep family

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 776; Mature: 776

Protein sequence:

>776_residues
MNKKLDQEQKRLDTVIETITQQIDKLENETGRRRAEVINIRKHFWDDVKVNTDTFDDYLETVINLRQQAQSLAVTQITHK
HTFNRLAALRRMHKAPYFGRIDFKEEGESAAEKIYIGVATLTDASGENFLIYDWRAPISSVYYDYPPGPAEYSTPGGVIH
GNVEKKLQYIIQNGEIDSMFDTSLTIGDEILQQALGKGTNKHMQSIVATIQREQNEIIRHDEGRLLIVQGAAGSGKTSAA
LQRIAYLLYKYREWLKADQIILFSPNSMFNSYVSNVLPELGEENMQQVTFQEYLNHRLSKSFDVEDPYEQLEYMLTETNS
PTYKTRNASIRFKASTQFFEMIRAYRQSLESSGMLFRGMKFRGKLIVSAKEITEQFYNTDFSLRFHNRIEKLTDWLNKQI
DAIEKAELKKPWVEEEIELLSKDEYQKAYKYLQKKGEFDDNSFQDFEKETRVLGRMIVRKKLKPLRKGVQTLRFINFTGI
YKQLFTDASWGTGEKPKEWDDICSLTVNMLDEGKLYYEDATPFLLLKELIEGFQTNRSIKHVLVDEAQDYSPFQFEFLKR
LFPAARMTVLGDFNQAIFAHASETVNFDTLTNLYGPDETNGINLTRSYRSTKPIIEFTRALVPEGNNIHAFERDGEKPTV
TKVANESELHERITAKVAELQKQNHNTIAIICKSAAESAAAYEALSSIEDIKLVKSTSAEYEQGVVIIPAYLAKGIEFDA
VIIYDASKDVYSDESVRRLFYTACTRAMHELQLYSVGEVSPFIIEADSESFELITP

Sequences:

>Translated_776_residues
MNKKLDQEQKRLDTVIETITQQIDKLENETGRRRAEVINIRKHFWDDVKVNTDTFDDYLETVINLRQQAQSLAVTQITHK
HTFNRLAALRRMHKAPYFGRIDFKEEGESAAEKIYIGVATLTDASGENFLIYDWRAPISSVYYDYPPGPAEYSTPGGVIH
GNVEKKLQYIIQNGEIDSMFDTSLTIGDEILQQALGKGTNKHMQSIVATIQREQNEIIRHDEGRLLIVQGAAGSGKTSAA
LQRIAYLLYKYREWLKADQIILFSPNSMFNSYVSNVLPELGEENMQQVTFQEYLNHRLSKSFDVEDPYEQLEYMLTETNS
PTYKTRNASIRFKASTQFFEMIRAYRQSLESSGMLFRGMKFRGKLIVSAKEITEQFYNTDFSLRFHNRIEKLTDWLNKQI
DAIEKAELKKPWVEEEIELLSKDEYQKAYKYLQKKGEFDDNSFQDFEKETRVLGRMIVRKKLKPLRKGVQTLRFINFTGI
YKQLFTDASWGTGEKPKEWDDICSLTVNMLDEGKLYYEDATPFLLLKELIEGFQTNRSIKHVLVDEAQDYSPFQFEFLKR
LFPAARMTVLGDFNQAIFAHASETVNFDTLTNLYGPDETNGINLTRSYRSTKPIIEFTRALVPEGNNIHAFERDGEKPTV
TKVANESELHERITAKVAELQKQNHNTIAIICKSAAESAAAYEALSSIEDIKLVKSTSAEYEQGVVIIPAYLAKGIEFDA
VIIYDASKDVYSDESVRRLFYTACTRAMHELQLYSVGEVSPFIIEADSESFELITP
>Mature_776_residues
MNKKLDQEQKRLDTVIETITQQIDKLENETGRRRAEVINIRKHFWDDVKVNTDTFDDYLETVINLRQQAQSLAVTQITHK
HTFNRLAALRRMHKAPYFGRIDFKEEGESAAEKIYIGVATLTDASGENFLIYDWRAPISSVYYDYPPGPAEYSTPGGVIH
GNVEKKLQYIIQNGEIDSMFDTSLTIGDEILQQALGKGTNKHMQSIVATIQREQNEIIRHDEGRLLIVQGAAGSGKTSAA
LQRIAYLLYKYREWLKADQIILFSPNSMFNSYVSNVLPELGEENMQQVTFQEYLNHRLSKSFDVEDPYEQLEYMLTETNS
PTYKTRNASIRFKASTQFFEMIRAYRQSLESSGMLFRGMKFRGKLIVSAKEITEQFYNTDFSLRFHNRIEKLTDWLNKQI
DAIEKAELKKPWVEEEIELLSKDEYQKAYKYLQKKGEFDDNSFQDFEKETRVLGRMIVRKKLKPLRKGVQTLRFINFTGI
YKQLFTDASWGTGEKPKEWDDICSLTVNMLDEGKLYYEDATPFLLLKELIEGFQTNRSIKHVLVDEAQDYSPFQFEFLKR
LFPAARMTVLGDFNQAIFAHASETVNFDTLTNLYGPDETNGINLTRSYRSTKPIIEFTRALVPEGNNIHAFERDGEKPTV
TKVANESELHERITAKVAELQKQNHNTIAIICKSAAESAAAYEALSSIEDIKLVKSTSAEYEQGVVIIPAYLAKGIEFDA
VIIYDASKDVYSDESVRRLFYTACTRAMHELQLYSVGEVSPFIIEADSESFELITP

Specific function: Catalyzes the unwinding of duplex DNA in the 3' to 5' direction; this reaction is dependent on the hydrolysis of ATP [H]

COG id: COG3973

COG function: function code R; Superfamily I DNA and RNA helicases

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 uvrD-like helicase ATP-binding domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000212
- InterPro:   IPR014016 [H]

Pfam domain/function: PF00580 UvrD-helicase [H]

EC number: =3.6.4.12 [H]

Molecular weight: Translated: 89315; Mature: 89315

Theoretical pI: Translated: 5.37; Mature: 5.37

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNKKLDQEQKRLDTVIETITQQIDKLENETGRRRAEVINIRKHFWDDVKVNTDTFDDYLE
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEECCCHHHHHHH
TVINLRQQAQSLAVTQITHKHTFNRLAALRRMHKAPYFGRIDFKEEGESAAEKIYIGVAT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHCCCHHHHEEEEEEEE
LTDASGENFLIYDWRAPISSVYYDYPPGPAEYSTPGGVIHGNVEKKLQYIIQNGEIDSMF
EECCCCCEEEEEECCCCHHHCCCCCCCCCCCCCCCCCEEECCHHHHHHHHHHCCCCCCHH
DTSLTIGDEILQQALGKGTNKHMQSIVATIQREQNEIIRHDEGRLLIVQGAAGSGKTSAA
CCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCHHHHH
LQRIAYLLYKYREWLKADQIILFSPNSMFNSYVSNVLPELGEENMQQVTFQEYLNHRLSK
HHHHHHHHHHHHHHHCCCCEEEECCHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHCC
SFDVEDPYEQLEYMLTETNSPTYKTRNASIRFKASTQFFEMIRAYRQSLESSGMLFRGMK
CCCCCCHHHHHHHHHHCCCCCCEEECCCEEEEECHHHHHHHHHHHHHHHHHCCCEEECCC
FRGKLIVSAKEITEQFYNTDFSLRFHNRIEKLTDWLNKQIDAIEKAELKKPWVEEEIELL
CCCEEEEEHHHHHHHHHCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHH
SKDEYQKAYKYLQKKGEFDDNSFQDFEKETRVLGRMIVRKKLKPLRKGVQTLRFINFTGI
CCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
YKQLFTDASWGTGEKPKEWDDICSLTVNMLDEGKLYYEDATPFLLLKELIEGFQTNRSIK
HHHHHCCCCCCCCCCCCHHHHHHHHHHHHHCCCCEEEECCCHHHHHHHHHHHHHCCCCHH
HVLVDEAQDYSPFQFEFLKRLFPAARMTVLGDFNQAIFAHASETVNFDTLTNLYGPDETN
HHHHHCCCCCCCHHHHHHHHHCCHHHHHHHCCCHHHHHHHCCCCCCHHHHHHCCCCCCCC
GINLTRSYRSTKPIIEFTRALVPEGNNIHAFERDGEKPTVTKVANESELHERITAKVAEL
CCEEEECCCCCCHHHHHHHHHCCCCCCEEEECCCCCCCCHHHHCCHHHHHHHHHHHHHHH
QKQNHNTIAIICKSAAESAAAYEALSSIEDIKLVKSTSAEYEQGVVIIPAYLAKGIEFDA
HHCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCEEEEEHHHHCCCCCCE
VIIYDASKDVYSDESVRRLFYTACTRAMHELQLYSVGEVSPFIIEADSESFELITP
EEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHEECCCCCCEEEECCCCCCEECCC
>Mature Secondary Structure
MNKKLDQEQKRLDTVIETITQQIDKLENETGRRRAEVINIRKHFWDDVKVNTDTFDDYLE
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEECCCHHHHHHH
TVINLRQQAQSLAVTQITHKHTFNRLAALRRMHKAPYFGRIDFKEEGESAAEKIYIGVAT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHCCCHHHHEEEEEEEE
LTDASGENFLIYDWRAPISSVYYDYPPGPAEYSTPGGVIHGNVEKKLQYIIQNGEIDSMF
EECCCCCEEEEEECCCCHHHCCCCCCCCCCCCCCCCCEEECCHHHHHHHHHHCCCCCCHH
DTSLTIGDEILQQALGKGTNKHMQSIVATIQREQNEIIRHDEGRLLIVQGAAGSGKTSAA
CCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCHHHHH
LQRIAYLLYKYREWLKADQIILFSPNSMFNSYVSNVLPELGEENMQQVTFQEYLNHRLSK
HHHHHHHHHHHHHHHCCCCEEEECCHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHCC
SFDVEDPYEQLEYMLTETNSPTYKTRNASIRFKASTQFFEMIRAYRQSLESSGMLFRGMK
CCCCCCHHHHHHHHHHCCCCCCEEECCCEEEEECHHHHHHHHHHHHHHHHHCCCEEECCC
FRGKLIVSAKEITEQFYNTDFSLRFHNRIEKLTDWLNKQIDAIEKAELKKPWVEEEIELL
CCCEEEEEHHHHHHHHHCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHH
SKDEYQKAYKYLQKKGEFDDNSFQDFEKETRVLGRMIVRKKLKPLRKGVQTLRFINFTGI
CCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
YKQLFTDASWGTGEKPKEWDDICSLTVNMLDEGKLYYEDATPFLLLKELIEGFQTNRSIK
HHHHHCCCCCCCCCCCCHHHHHHHHHHHHHCCCCEEEECCCHHHHHHHHHHHHHCCCCHH
HVLVDEAQDYSPFQFEFLKRLFPAARMTVLGDFNQAIFAHASETVNFDTLTNLYGPDETN
HHHHHCCCCCCCHHHHHHHHHCCHHHHHHHCCCHHHHHHHCCCCCCHHHHHHCCCCCCCC
GINLTRSYRSTKPIIEFTRALVPEGNNIHAFERDGEKPTVTKVANESELHERITAKVAEL
CCEEEECCCCCCHHHHHHHHHCCCCCCEEEECCCCCCCCHHHHCCHHHHHHHHHHHHHHH
QKQNHNTIAIICKSAAESAAAYEALSSIEDIKLVKSTSAEYEQGVVIIPAYLAKGIEFDA
HHCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCEEEEEHHHHCCCCCCE
VIIYDASKDVYSDESVRRLFYTACTRAMHELQLYSVGEVSPFIIEADSESFELITP
EEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHEECCCCCCEEEECCCCCCEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]