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The map label for this gene is mrdB [H]

Identifier: 218902230

GI number: 218902230

Start: 1063448

End: 1064713

Strand: Direct

Name: mrdB [H]

Synonym: BCAH820_1112

Alternate gene names: 218902230

Gene position: 1063448-1064713 (Clockwise)

Preceding gene: 218902229

Following gene: 218902232

Centisome position: 20.05

GC content: 35.78

Gene sequence:

>1266_bases
TTGAATAAAAAAAGGGAGCGTTTTTTAAAAGAAGTTACGAACCATATTAAATCAAAAGAAGCGAAGGACTTGGTGGCAGC
GGAACTAGACTTTCACTTAAAACAGACGAAGAATATGTGGATAGGGAAAGGATTAAGTGAGGAAATTGCTGAAGATAAGG
CTGTTGAGCAAATGGGGAGTCCGATTAAACTGGGACAAGAACTTAACAAACTGCATAAGCCAAAGGTTGATTGGTTCTTA
CTTATTTTATTAGTGGCTGCGATGGGGTTAGGGTTTTTGCCGGTTATAGCTTTTGGATATATGAATGATTTACTAATGGA
TAAGGTGATATTTGTTGTTCTTGGTATTGCAACAGCGTTAGGGATGATGCTGATTAATTATCGGAAGTTAGAGAGATTAG
GATGGTTGTTTTATACAATTGGTGTACTTATCTTGTTAATGCTATACTGCTTTCCGAATGCTGGGATGCTTGGAGAACCG
ATAATAAAAGTTGGTCCTATTGCAATTGACCGTTTAATGGCAGTGCCGTTCTTTTTTCTAGCTTGGGCTTCTTTTTTCAA
TAATAGTAGGATAAAAGTAATGCATCTTGTGGCTCTTTATTTATTTTCTTTGTATTTATTTTTAATTGGCGCAGCTTTTT
CAGTGATTTTTATTTATATCACGATGGTATTCGTTATGCTTTGGTGGAGTAAGTTAGGGAAGAAAAAGGCATTAATTATT
ACAATTGTACCAATCTGTTTATTGATTATAGGGGTCTATTTTTCCTGGCCCACAGTAAAAGGAGTTTATTTGGATAGATT
TTTAGGGTATTTGAATCCAGAGCGTGATGCACAGGGCGCAGGATTTATGTATATACGTTTAAAGGAGGTAATGTCGTCAG
CAGGTTGGTTTGGTACATACGGAGATGTAAAGTTCATCCCTAATCCAGATACTGATTTTGTATTTGCAAGTTTGACTTAT
TATTATGGATATGTGCTTGCACTGGTCCTTGTCTTAATTCTTTCTCTTTTTGTAGCACGGTTAATCTTCATATCTTATAC
AATAAATGACCGGTATGGTAAATTGCTTCTCATTGGAGGTATGACTCTTTTCGTAGTGCAATTCCTTTATAACGTCGGTA
TGATTTTAGGTTTATTACCGATTACTGCTATATCACTACCTTTTATTAGTTATGGATTAACACCAACTGTATTTCATGCG
CTTGTAATGGGAATCGTACTAAGTGTATATCGACGTAAAGACATTCCAGCGAGAAAATCAGCTTAA

Upstream 100 bases:

>100_bases
CAATTAAATGATAAAGGAAACAAGATGCTGCGAAAGGCAGAGAAGAATGCTACGAAGGCACGATTTATATTAAAAGGCTT
AGTACAGGAGTGAGAAAAAA

Downstream 100 bases:

>100_bases
AAAACAAACCACCTAGTCCCTATATTTTTTAGGGTGTAGGTGGTTTTATTTACACACTTAACAAGTTTTTCCGTTCTCAA
CTTCTCCGCATGAATCTGGA

Product: cell division protein, FtsW/RodA/SpoVE family

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 421; Mature: 421

Protein sequence:

>421_residues
MNKKRERFLKEVTNHIKSKEAKDLVAAELDFHLKQTKNMWIGKGLSEEIAEDKAVEQMGSPIKLGQELNKLHKPKVDWFL
LILLVAAMGLGFLPVIAFGYMNDLLMDKVIFVVLGIATALGMMLINYRKLERLGWLFYTIGVLILLMLYCFPNAGMLGEP
IIKVGPIAIDRLMAVPFFFLAWASFFNNSRIKVMHLVALYLFSLYLFLIGAAFSVIFIYITMVFVMLWWSKLGKKKALII
TIVPICLLIIGVYFSWPTVKGVYLDRFLGYLNPERDAQGAGFMYIRLKEVMSSAGWFGTYGDVKFIPNPDTDFVFASLTY
YYGYVLALVLVLILSLFVARLIFISYTINDRYGKLLLIGGMTLFVVQFLYNVGMILGLLPITAISLPFISYGLTPTVFHA
LVMGIVLSVYRRKDIPARKSA

Sequences:

>Translated_421_residues
MNKKRERFLKEVTNHIKSKEAKDLVAAELDFHLKQTKNMWIGKGLSEEIAEDKAVEQMGSPIKLGQELNKLHKPKVDWFL
LILLVAAMGLGFLPVIAFGYMNDLLMDKVIFVVLGIATALGMMLINYRKLERLGWLFYTIGVLILLMLYCFPNAGMLGEP
IIKVGPIAIDRLMAVPFFFLAWASFFNNSRIKVMHLVALYLFSLYLFLIGAAFSVIFIYITMVFVMLWWSKLGKKKALII
TIVPICLLIIGVYFSWPTVKGVYLDRFLGYLNPERDAQGAGFMYIRLKEVMSSAGWFGTYGDVKFIPNPDTDFVFASLTY
YYGYVLALVLVLILSLFVARLIFISYTINDRYGKLLLIGGMTLFVVQFLYNVGMILGLLPITAISLPFISYGLTPTVFHA
LVMGIVLSVYRRKDIPARKSA
>Mature_421_residues
MNKKRERFLKEVTNHIKSKEAKDLVAAELDFHLKQTKNMWIGKGLSEEIAEDKAVEQMGSPIKLGQELNKLHKPKVDWFL
LILLVAAMGLGFLPVIAFGYMNDLLMDKVIFVVLGIATALGMMLINYRKLERLGWLFYTIGVLILLMLYCFPNAGMLGEP
IIKVGPIAIDRLMAVPFFFLAWASFFNNSRIKVMHLVALYLFSLYLFLIGAAFSVIFIYITMVFVMLWWSKLGKKKALII
TIVPICLLIIGVYFSWPTVKGVYLDRFLGYLNPERDAQGAGFMYIRLKEVMSSAGWFGTYGDVKFIPNPDTDFVFASLTY
YYGYVLALVLVLILSLFVARLIFISYTINDRYGKLLLIGGMTLFVVQFLYNVGMILGLLPITAISLPFISYGLTPTVFHA
LVMGIVLSVYRRKDIPARKSA

Specific function: This is one of the proteins responsible for the rod shape of the cell. It is required for the expression of the enzymatic activity of PBP2, which is thought to synthesize peptidoglycan in the step of initiation of cell elongation [H]

COG id: COG0772

COG function: function code D; Bacterial cell division membrane protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ftsW/rodA/spoVE family [H]

Homologues:

Organism=Escherichia coli, GI1786853, Length=161, Percent_Identity=30.4347826086957, Blast_Score=74, Evalue=2e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001182
- InterPro:   IPR018365
- InterPro:   IPR011923 [H]

Pfam domain/function: PF01098 FTSW_RODA_SPOVE [H]

EC number: NA

Molecular weight: Translated: 47721; Mature: 47721

Theoretical pI: Translated: 9.94; Mature: 9.94

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
4.5 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
4.5 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNKKRERFLKEVTNHIKSKEAKDLVAAELDFHLKQTKNMWIGKGLSEEIAEDKAVEQMGS
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHCCCCHHHHHHHHHHHHCCC
PIKLGQELNKLHKPKVDWFLLILLVAAMGLGFLPVIAFGYMNDLLMDKVIFVVLGIATAL
CHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GMMLINYRKLERLGWLFYTIGVLILLMLYCFPNAGMLGEPIIKVGPIAIDRLMAVPFFFL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHH
AWASFFNNSRIKVMHLVALYLFSLYLFLIGAAFSVIFIYITMVFVMLWWSKLGKKKALII
HHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHH
TIVPICLLIIGVYFSWPTVKGVYLDRFLGYLNPERDAQGAGFMYIRLKEVMSSAGWFGTY
HHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHCCCCCCCC
GDVKFIPNPDTDFVFASLTYYYGYVLALVLVLILSLFVARLIFISYTINDRYGKLLLIGG
CCCEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCEEEECC
MTLFVVQFLYNVGMILGLLPITAISLPFISYGLTPTVFHALVMGIVLSVYRRKDIPARKS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCCC
A
C
>Mature Secondary Structure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C

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]