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The map label for this gene is tenA [H]

Identifier: 218901920

GI number: 218901920

Start: 766549

End: 767244

Strand: Direct

Name: tenA [H]

Synonym: BCAH820_0802

Alternate gene names: 218901920

Gene position: 766549-767244 (Clockwise)

Preceding gene: 218901916

Following gene: 218901921

Centisome position: 14.46

GC content: 35.36

Gene sequence:

>696_bases
ATGAAATTTTGCGATAGATTATTAGAAACTGTACAACCAGTTTGGGAGATGAGTCATAATCATCCGTTTGTAGTAGGTAT
GGGGGATGGTACGTTAGAAAAAGATAAGTTTCAGTATTATATTATTCAAGATTATTTATATCTGCTAGATTATGCAAAGC
TATATGCTATTGGCGTTGTAAAGGCAACGAATCCACAAGTAATGSGGAAATTTGCTGAACAAATTGATGGAATATTAAAT
GGAGAAATGACAATCCATAAACAGTATGCAAAAAGACTTGGAATTTCTATAGAGGAGATAGAGTCTGCAAAGCCATCTGC
TAAAAATTTAGCTTATACAAATKWSATGATGTCTGTATCTCAAAATGGCACACTTGCAGAATTAATAGCAGCACTTCTTC
CGTGTATGTGGAGCTACTGGGAAATTGGAAAGCGTTTAAATGATATTCCTGGAGCAAGGGATCATGAATTTTTTGGTGAG
TGGATTCAAGGATATAGTTCTGAAGAGTACGGCAACCTCTGTATTTGGTTAATCGATTTATTAAATGAAATGGCAGTTGG
AAAGTCTGAAAAAGAGCTAGACCGATTWGAGGAGAWTTTCCTATATTCCAGTCGATTTGAATATTTATTCTGGGATATGT
CCTATCGTAAGGAGATGTGGGGATTTGAGGAGCAAGAACATACTACAGTTTCATAA

Upstream 100 bases:

>100_bases
GTGGAACAACGAATAAATTATAATTTTATTTGCTGTAACCACTTCTTATATAAAGAAGTGGTTTTTTATTTATATACACA
TACCGGAAGGGGATAGAGAA

Downstream 100 bases:

>100_bases
TGTTTCTTTTCATTATGATGAGAAGCCAATCATCAATGAATTAAATGCTTCTATACAAGATAAAGAGTTTGTAAGTATTA
TCGGACCGAGTGGTTGCGGA

Product: putative transcriptional activator TenA

Products: NA

Alternate protein names: Thiaminase II; Transcriptional activator tenA [H]

Number of amino acids: Translated: 231; Mature: 231

Protein sequence:

>231_residues
MKFCDRLLETVQPVWEMSHNHPFVVGMGDGTLEKDKFQYYIIQDYLYLLDYAKLYAIGVVKATNPQVMXKFAEQIDGILN
GEMTIHKQYAKRLGISIEEIESAKPSAKNLAYTNXMMSVSQNGTLAELIAALLPCMWSYWEIGKRLNDIPGARDHEFFGE
WIQGYSSEEYGNLCIWLIDLLNEMAVGKSEKELDRXEEXFLYSSRFEYLFWDMSYRKEMWGFEEQEHTTVS

Sequences:

>Translated_231_residues
MKFCDRLLETVQPVWEMSHNHPFVVGMGDGTLEKDKFQYYIIQDYLYLLDYAKLYAIGVVKATNPQVMXKFAEQIDGILN
GEMTIHKQYAKRLGISIEEIESAKPSAKNLAYTNXMMSVSQNGTLAELIAALLPCMWSYWEIGKRLNDIPGARDHEFFGE
WIQGYSSEEYGNLCIWLIDLLNEMAVGKSEKELDRXEEXFLYSSRFEYLFWDMSYRKEMWGFEEQEHTTVS
>Mature_231_residues
MKFCDRLLETVQPVWEMSHNHPFVVGMGDGTLEKDKFQYYIIQDYLYLLDYAKLYAIGVVKATNPQVMXKFAEQIDGILN
GEMTIHKQYAKRLGISIEEIESAKPSAKNLAYTNXMMSVSQNGTLAELIAALLPCMWSYWEIGKRLNDIPGARDHEFFGE
WIQGYSSEEYGNLCIWLIDLLNEMAVGKSEKELDRXEEXFLYSSRFEYLFWDMSYRKEMWGFEEQEHTTVS

Specific function: Stimulates the production of several extracellular degradative enzymes at the transcriptional level, probably by interfering with degS and degU, which are required for this effect. Is not an essential protein, but affects the sporulation frequency [H]

COG id: COG0819

COG function: function code K; Putative transcription activator

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the thiaminase-2 family [H]

Homologues:

Organism=Saccharomyces cerevisiae, GI6324517, Length=210, Percent_Identity=30.4761904761905, Blast_Score=89, Evalue=7e-19,
Organism=Saccharomyces cerevisiae, GI6324997, Length=205, Percent_Identity=28.780487804878, Blast_Score=83, Evalue=3e-17,
Organism=Saccharomyces cerevisiae, GI6325378, Length=203, Percent_Identity=27.0935960591133, Blast_Score=79, Evalue=5e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016084
- InterPro:   IPR004305 [H]

Pfam domain/function: PF03070 TENA_THI-4 [H]

EC number: =3.5.99.2 [H]

Molecular weight: Translated: 26746; Mature: 26746

Theoretical pI: Translated: 4.51; Mature: 4.51

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
4.8 %Met     (Translated Protein)
6.1 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
4.8 %Met     (Mature Protein)
6.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKFCDRLLETVQPVWEMSHNHPFVVGMGDGTLEKDKFQYYIIQDYLYLLDYAKLYAIGVV
CCHHHHHHHHHHHHHHCCCCCCEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHE
KATNPQVMXKFAEQIDGILNGEMTIHKQYAKRLGISIEEIESAKPSAKNLAYTNXMMSVS
ECCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCHHHHHCCCCCHHHHHHHHHHHHHC
QNGTLAELIAALLPCMWSYWEIGKRLNDIPGARDHEFFGEWIQGYSSEEYGNLCIWLIDL
CCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCCCCCCHHHHHHHH
LNEMAVGKSEKELDRXEEXFLYSSRFEYLFWDMSYRKEMWGFEEQEHTTVS
HHHHHCCCCHHHHHHHHHHHHHHCCCHHHEECHHHHHHHCCCCCCCCCCCC
>Mature Secondary Structure
MKFCDRLLETVQPVWEMSHNHPFVVGMGDGTLEKDKFQYYIIQDYLYLLDYAKLYAIGVV
CCHHHHHHHHHHHHHHCCCCCCEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHE
KATNPQVMXKFAEQIDGILNGEMTIHKQYAKRLGISIEEIESAKPSAKNLAYTNXMMSVS
ECCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCHHHHHCCCCCHHHHHHHHHHHHHC
QNGTLAELIAALLPCMWSYWEIGKRLNDIPGARDHEFFGEWIQGYSSEEYGNLCIWLIDL
CCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCCCCCCHHHHHHHH
LNEMAVGKSEKELDRXEEXFLYSSRFEYLFWDMSYRKEMWGFEEQEHTTVS
HHHHHCCCCHHHHHHHHHHHHHHCCCHHHEECHHHHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1898926; 9384377 [H]