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The map label for this gene is qoxA [H]

Identifier: 218901897

GI number: 218901897

Start: 736277

End: 737152

Strand: Reverse

Name: qoxA [H]

Synonym: BCAH820_0758

Alternate gene names: 218901897

Gene position: 737152-736277 (Counterclockwise)

Preceding gene: 218901906

Following gene: 218901896

Centisome position: 13.9

GC content: 37.67

Gene sequence:

>876_bases
GTGCAACTAAAGAAAGCGTTTTGGAAGTTGGCTTCGCTTCTTCCGTTATCATTACTTCTGTTCCTCGGTGGCTGTGATAA
AAAACTCGCAGTATTAAATCCGCAAGGACCTGTTGCAAAAGCACAGTATGATTTAATTGTTTGGTCATTCTTGCTTATGT
CATTAATTATCGCAATTGTATTCATCTTGTTTACAGTCATCTTGATTCGTTATCGTGAAAAACCAGAGAATATGGACTAT
GAGCCACCTGAACAACACGGTAACACATTATTAGAAATCATTTGGACGCTTGTTCCTGTTATTATCGTTATCGCATTATC
GATTCCAACAGTAAAAGCAACTTATGCTTCGGAAGAGGTTCCGGAAGAGTCCAAACATATTAAACCAGTGGAGATTTATG
TTACATCTGCAAACTGGAAATGGTTATTCAGTTACCCAGAGGAAAAAATTGAAACCGTTAACTATTTAAACATCCCAGCT
GGTGTACCAATTCAATTCAAACTGACTTCTGTCGGCCCAATGAATGCTTTCTGGGTACCAGAACTTGGTGGTATGAAGTA
CACAATGGATGGCATGATTATGGACCTTTATTTACAAGCTGATAAGCCAGGTTCTTACCTAGGCCGTAGCGCGAACTTCT
CTGGTGAAGGATTTACTCACATGGAGTTCGAAGTTGAAGCAAAAACTAAAGAGAAATATGACAAGTGGGTTAAAGAAGTA
CAACAAACTGCTCCTAAACTAACAGAAGATAAGTACAACGAAATTGTTAAACCTGGTGTAGTTGGTCGTATGACATTCTC
TAGCCATCACTTAAGTTATGTAGATCCAAAATCACTTGAATATTGTGATTACAACTACTACAAAAACAAAAAATAA

Upstream 100 bases:

>100_bases
TTTTAACAATATCTCAAAAACTATTGCCTTCTATAAATTAATAGGTTTATATTGTTTTATTGGCATAGTTTCAATCCAAG
GAGAAAGGAGATTTTCAATC

Downstream 100 bases:

>100_bases
TAGCTATAATTCCAACAGATTGGAGTGAACACAGTGAAGCTTGATGAATTCTTTGTCACAGGTGACCCGATTATTTACGG
TGCAGACGCTTCTATCGTTC

Product: cytochrome aa3 quinol oxidase, subunit II

Products: ferricytochrome c; H2O

Alternate protein names: Cytochrome aa(3) subunit 2; Quinol oxidase polypeptide II [H]

Number of amino acids: Translated: 291; Mature: 291

Protein sequence:

>291_residues
MQLKKAFWKLASLLPLSLLLFLGGCDKKLAVLNPQGPVAKAQYDLIVWSFLLMSLIIAIVFILFTVILIRYREKPENMDY
EPPEQHGNTLLEIIWTLVPVIIVIALSIPTVKATYASEEVPEESKHIKPVEIYVTSANWKWLFSYPEEKIETVNYLNIPA
GVPIQFKLTSVGPMNAFWVPELGGMKYTMDGMIMDLYLQADKPGSYLGRSANFSGEGFTHMEFEVEAKTKEKYDKWVKEV
QQTAPKLTEDKYNEIVKPGVVGRMTFSSHHLSYVDPKSLEYCDYNYYKNKK

Sequences:

>Translated_291_residues
MQLKKAFWKLASLLPLSLLLFLGGCDKKLAVLNPQGPVAKAQYDLIVWSFLLMSLIIAIVFILFTVILIRYREKPENMDY
EPPEQHGNTLLEIIWTLVPVIIVIALSIPTVKATYASEEVPEESKHIKPVEIYVTSANWKWLFSYPEEKIETVNYLNIPA
GVPIQFKLTSVGPMNAFWVPELGGMKYTMDGMIMDLYLQADKPGSYLGRSANFSGEGFTHMEFEVEAKTKEKYDKWVKEV
QQTAPKLTEDKYNEIVKPGVVGRMTFSSHHLSYVDPKSLEYCDYNYYKNKK
>Mature_291_residues
MQLKKAFWKLASLLPLSLLLFLGGCDKKLAVLNPQGPVAKAQYDLIVWSFLLMSLIIAIVFILFTVILIRYREKPENMDY
EPPEQHGNTLLEIIWTLVPVIIVIALSIPTVKATYASEEVPEESKHIKPVEIYVTSANWKWLFSYPEEKIETVNYLNIPA
GVPIQFKLTSVGPMNAFWVPELGGMKYTMDGMIMDLYLQADKPGSYLGRSANFSGEGFTHMEFEVEAKTKEKYDKWVKEV
QQTAPKLTEDKYNEIVKPGVVGRMTFSSHHLSYVDPKSLEYCDYNYYKNKK

Specific function: Catalyzes quinol oxidation with the concomitant reduction of oxygen to water. Subunit II transfers the electrons from a quinol to the binuclear center of the catalytic subunit I [H]

COG id: COG1622

COG function: function code C; Heme/copper-type cytochrome/quinol oxidases, subunit 2

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cytochrome c oxidase subunit 2 family [H]

Homologues:

Organism=Escherichia coli, GI1786635, Length=251, Percent_Identity=37.8486055776892, Blast_Score=164, Evalue=5e-42,
Organism=Saccharomyces cerevisiae, GI6226540, Length=216, Percent_Identity=22.2222222222222, Blast_Score=62, Evalue=8e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012141
- InterPro:   IPR008972
- InterPro:   IPR006332
- InterPro:   IPR015964
- InterPro:   IPR002429
- InterPro:   IPR011759 [H]

Pfam domain/function: PF02790 COX2_TM [H]

EC number: 1.9.3.1

Molecular weight: Translated: 33337; Mature: 33337

Theoretical pI: Translated: 6.68; Mature: 6.68

Prosite motif: PS00013 PROKAR_LIPOPROTEIN ; PS50999 COX2_TM ; PS50857 COX2_CUA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQLKKAFWKLASLLPLSLLLFLGGCDKKLAVLNPQGPVAKAQYDLIVWSFLLMSLIIAIV
CCHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHH
FILFTVILIRYREKPENMDYEPPEQHGNTLLEIIWTLVPVIIVIALSIPTVKATYASEEV
HHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCC
PEESKHIKPVEIYVTSANWKWLFSYPEEKIETVNYLNIPAGVPIQFKLTSVGPMNAFWVP
CCHHHCCCEEEEEEECCCCEEEECCCHHHHCCCEEEECCCCCCEEEEEECCCCCCEEECC
ELGGMKYTMDGMIMDLYLQADKPGSYLGRSANFSGEGFTHMEFEVEAKTKEKYDKWVKEV
CCCCCEEECCCEEEEEEEECCCCHHHCCCCCCCCCCCEEEEEEEEECHHHHHHHHHHHHH
QQTAPKLTEDKYNEIVKPGVVGRMTFSSHHLSYVDPKSLEYCDYNYYKNKK
HHHCCCCCHHHHHHHCCCCCEEEEEECCCCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MQLKKAFWKLASLLPLSLLLFLGGCDKKLAVLNPQGPVAKAQYDLIVWSFLLMSLIIAIV
CCHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHH
FILFTVILIRYREKPENMDYEPPEQHGNTLLEIIWTLVPVIIVIALSIPTVKATYASEEV
HHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCC
PEESKHIKPVEIYVTSANWKWLFSYPEEKIETVNYLNIPAGVPIQFKLTSVGPMNAFWVP
CCHHHCCCEEEEEEECCCCEEEECCCHHHHCCCEEEECCCCCCEEEEEECCCCCCEEECC
ELGGMKYTMDGMIMDLYLQADKPGSYLGRSANFSGEGFTHMEFEVEAKTKEKYDKWVKEV
CCCCCEEECCCEEEEEEEECCCCHHHCCCCCCCCCCCEEEEEEEEECHHHHHHHHHHHHH
QQTAPKLTEDKYNEIVKPGVVGRMTFSSHHLSYVDPKSLEYCDYNYYKNKK
HHHCCCCCHHHHHHHCCCCCEEEEEECCCCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ferrocytochrome c; O2

Specific reaction: 4 ferrocytochrome c + O2 = 4 ferricytochrome c + 2 H2O

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 12721629 [H]