| Definition | Bacillus cereus AH820, complete genome. |
|---|---|
| Accession | NC_011773 |
| Length | 5,302,683 |
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The map label for this gene is inhA [H]
Identifier: 218901867
GI number: 218901867
Start: 703319
End: 705718
Strand: Direct
Name: inhA [H]
Synonym: BCAH820_0728
Alternate gene names: 218901867
Gene position: 703319-705718 (Clockwise)
Preceding gene: 218901866
Following gene: 218901869
Centisome position: 13.26
GC content: 36.71
Gene sequence:
>2400_bases ATGAGAAGAAAAGCACCACTTAAAGTGTTATCGTCATTAGCAATTGCGGCAATTATCGGATGTACATCTGTAATGAGTGC TCCATTAGCGTACGCAGAAACGCCAGCAAAAGAGAAAGAAAATGTGTCTACAACACCAATTGATTACAATTTAATTCAAG AAGATCGTCTAGCGGAAGCGCTGAAAGAAAGAGGAACAATTAATCCAGCATCTTCTAAAGAAGAGACGAAAAAGGCTGTA GAGAAATATATTGAAAAGAAACAAGGGGATCAGGCAAATAAAGAAATTCTTCCAGCTGATACTGCTAAAGAGGCATCTGA TTTCGTGAAAAAAGTAAAAGAGAAAAAAATGGAAGAAAAGGAGAAAGTAAAGAAACCTGAAAAAAATGTTAGCCCTGAGC AAAAGCCTGAACCAAATAAAAAACAATTGAATGGACAAGTTCCAACATCTAAAGCAAAGCAAGCGCCATATAAGGGGTCT GTTCGAACGGATAAAGTATTAGTATTACTCGTTGAATTTAGTGATTATAAACATAATAATATCGATCAAACACCAGGGTA TATGTATTCGAATGACTTTAGTAGAGAGCATTATCAAAAGATGTTATTTGGTAATGAGCCGTACACATTATTTGATGGTT CAAAAGTAAAAACGTTTAAACAATATTATGAAGAGCAGTCTGGCGGTAGTTATACGACTGATGGATATGTAACAGAATGG TTAACTGTTCCAGGAAAAGCATCTGACTACGGTGCTGATGGTAGCAGTGGTCATGATAACAAAGGTCCAAAAGGCGCACG TGATTTAGTGAAAGAAGCTTTACATGCAGCTGCTGAGAAAGGTTTAGATTTATCTCAATTTGATCAGTTTGATAGATATG ATACAAATAGTGATGGAAATCAAAATGAACCTGACGGTGTAATTGATCATTTAATGGTAATCCATGCTGGTGTTGGTCAA GAAGCTGGTGGAGGTAAATTAGGTGATGATGCCATTTGGTCACATCGTTCAAAATTAGCAATAGATCCAGTAGCAATTGA AGGGACAAAATCAAAGGTAGATTACTTTGGTGGCAAAGTAGCAGCACATGATTACACAATTGAACCAGAAGATGGAGCAG TAGGTGTATTTGCGCATGAATTTGGACATGATCTTGGCTTACCAGATGAATATGATACGAAATATACTGGAACTGGTTCA CCTGTCGAAGCTTGGTCATTAATGAGTGGAGGTAGTTGGACAGGGAAAATTGCAGGAACAGAGCCAACTAGTTTTTCACC ACAAAATAAAGATTTCTTACAAAAGAATATGGGGGGCAACTGGGCAAAAATTTTAGAAGTAGATTACGATAAAATTAAGC GTGGTGTAGGAGTTCCTACATATATTGATCAAAGTGTTACGAAATCAAATCGTCCAGGCGTTGTACGTGTTAACTTACCA GGCAAAAGTGTTGAAACGATTAAACCGGAGTTTGGAAAGCATGCATATTATAGTACAAGAGGCGATGATATGCATACAAC ATTAGAAACACCGTTCTTTGATTTAACAAAAGGAACAAATGCAAAGTTTGATTATAAAGCAAATTATGAGTTAGAAGCAG AGTGCGATTTTGTTGAAGTTCACGCAGTAACAGAAGATGGAACGAAAACATTAATTGATAGACTTGGAGAAAAAGTAGTC CAAGGAGATAAAGATACAACAGATGGAAAATGGATTGATAAATCATATGATTTAAGTCAATTTAAAGGAAAAAAAGTGAA ACTGCAATTCGATTATATTACAGATCCAGCTGTAACATATAAAGGTTTCGCGATGGATCATGTAAATGTAACTGTTGATG GACAAGTAGTATTTTCTGATGATGCAGAAGGACAGTCTAAAATGAATTTAAATGGTTTTGTTGTTTCTGATGGGACAGAG AAAAAAGCTCATTATTACTACTTAGAGTGGAGAAACTATGCGGGATCAGATAATGGATTAAAAGCAGGAAAAGGTCCAGT GTATAATACAGGTCTTGTCGTTTGGTATGCAGATGATAGCTTTAAAGATAACTGGGTTGGGGTGCATCCAGGTGAAGGAT TCCTTGGGGTTGTAGACTCTCATCCAGAAGCATTTGTTGGCAATTTAAACGGAAAACCAACTTACGGTAACACAGGTATG CAAATTGCAGACGCTGCATTTTCATTTGATCAAACACCAGCATGGAGTGTAAATTCATTAACACGTGGACAGTTTAACTA TTCTGGATTACATGGTGTTACAACTTTTGATGATTCAAAAGTATATAGTAACAACCAAATTGCAGACGCAGGAAGAAAAG TTCCGAACCTTGGACTTAAATTCCAAGTTGTTGGACAGGCAGATGATAAATCAGCAGGCGCTGTTTGGATTAAACGTTAA
Upstream 100 bases:
>100_bases GAATTATGCCTTTTTATATAGGGAGGGCAGTAAACGGGGATTTCGACAAAAATGCACTTATTTATCTGAATTTTAAGTTT TATAAAAGGAGAGAAATAGA
Downstream 100 bases:
>100_bases TAACAGAAAAGCACATTCTTCATATGAAGAGTGTGCTTTTTAAATTGTACAGTAAGTTATTATTTTAGCTTATGTAATAC AAGTGTCTGTTCATATGTAG
Product: immune inhibitor A metalloprotease
Products: NA
Alternate protein names: NA
Number of amino acids: Translated: 799; Mature: 799
Protein sequence:
>799_residues MRRKAPLKVLSSLAIAAIIGCTSVMSAPLAYAETPAKEKENVSTTPIDYNLIQEDRLAEALKERGTINPASSKEETKKAV EKYIEKKQGDQANKEILPADTAKEASDFVKKVKEKKMEEKEKVKKPEKNVSPEQKPEPNKKQLNGQVPTSKAKQAPYKGS VRTDKVLVLLVEFSDYKHNNIDQTPGYMYSNDFSREHYQKMLFGNEPYTLFDGSKVKTFKQYYEEQSGGSYTTDGYVTEW LTVPGKASDYGADGSSGHDNKGPKGARDLVKEALHAAAEKGLDLSQFDQFDRYDTNSDGNQNEPDGVIDHLMVIHAGVGQ EAGGGKLGDDAIWSHRSKLAIDPVAIEGTKSKVDYFGGKVAAHDYTIEPEDGAVGVFAHEFGHDLGLPDEYDTKYTGTGS PVEAWSLMSGGSWTGKIAGTEPTSFSPQNKDFLQKNMGGNWAKILEVDYDKIKRGVGVPTYIDQSVTKSNRPGVVRVNLP GKSVETIKPEFGKHAYYSTRGDDMHTTLETPFFDLTKGTNAKFDYKANYELEAECDFVEVHAVTEDGTKTLIDRLGEKVV QGDKDTTDGKWIDKSYDLSQFKGKKVKLQFDYITDPAVTYKGFAMDHVNVTVDGQVVFSDDAEGQSKMNLNGFVVSDGTE KKAHYYYLEWRNYAGSDNGLKAGKGPVYNTGLVVWYADDSFKDNWVGVHPGEGFLGVVDSHPEAFVGNLNGKPTYGNTGM QIADAAFSFDQTPAWSVNSLTRGQFNYSGLHGVTTFDDSKVYSNNQIADAGRKVPNLGLKFQVVGQADDKSAGAVWIKR
Sequences:
>Translated_799_residues MRRKAPLKVLSSLAIAAIIGCTSVMSAPLAYAETPAKEKENVSTTPIDYNLIQEDRLAEALKERGTINPASSKEETKKAV EKYIEKKQGDQANKEILPADTAKEASDFVKKVKEKKMEEKEKVKKPEKNVSPEQKPEPNKKQLNGQVPTSKAKQAPYKGS VRTDKVLVLLVEFSDYKHNNIDQTPGYMYSNDFSREHYQKMLFGNEPYTLFDGSKVKTFKQYYEEQSGGSYTTDGYVTEW LTVPGKASDYGADGSSGHDNKGPKGARDLVKEALHAAAEKGLDLSQFDQFDRYDTNSDGNQNEPDGVIDHLMVIHAGVGQ EAGGGKLGDDAIWSHRSKLAIDPVAIEGTKSKVDYFGGKVAAHDYTIEPEDGAVGVFAHEFGHDLGLPDEYDTKYTGTGS PVEAWSLMSGGSWTGKIAGTEPTSFSPQNKDFLQKNMGGNWAKILEVDYDKIKRGVGVPTYIDQSVTKSNRPGVVRVNLP GKSVETIKPEFGKHAYYSTRGDDMHTTLETPFFDLTKGTNAKFDYKANYELEAECDFVEVHAVTEDGTKTLIDRLGEKVV QGDKDTTDGKWIDKSYDLSQFKGKKVKLQFDYITDPAVTYKGFAMDHVNVTVDGQVVFSDDAEGQSKMNLNGFVVSDGTE KKAHYYYLEWRNYAGSDNGLKAGKGPVYNTGLVVWYADDSFKDNWVGVHPGEGFLGVVDSHPEAFVGNLNGKPTYGNTGM QIADAAFSFDQTPAWSVNSLTRGQFNYSGLHGVTTFDDSKVYSNNQIADAGRKVPNLGLKFQVVGQADDKSAGAVWIKR >Mature_799_residues MRRKAPLKVLSSLAIAAIIGCTSVMSAPLAYAETPAKEKENVSTTPIDYNLIQEDRLAEALKERGTINPASSKEETKKAV EKYIEKKQGDQANKEILPADTAKEASDFVKKVKEKKMEEKEKVKKPEKNVSPEQKPEPNKKQLNGQVPTSKAKQAPYKGS VRTDKVLVLLVEFSDYKHNNIDQTPGYMYSNDFSREHYQKMLFGNEPYTLFDGSKVKTFKQYYEEQSGGSYTTDGYVTEW LTVPGKASDYGADGSSGHDNKGPKGARDLVKEALHAAAEKGLDLSQFDQFDRYDTNSDGNQNEPDGVIDHLMVIHAGVGQ EAGGGKLGDDAIWSHRSKLAIDPVAIEGTKSKVDYFGGKVAAHDYTIEPEDGAVGVFAHEFGHDLGLPDEYDTKYTGTGS PVEAWSLMSGGSWTGKIAGTEPTSFSPQNKDFLQKNMGGNWAKILEVDYDKIKRGVGVPTYIDQSVTKSNRPGVVRVNLP GKSVETIKPEFGKHAYYSTRGDDMHTTLETPFFDLTKGTNAKFDYKANYELEAECDFVEVHAVTEDGTKTLIDRLGEKVV QGDKDTTDGKWIDKSYDLSQFKGKKVKLQFDYITDPAVTYKGFAMDHVNVTVDGQVVFSDDAEGQSKMNLNGFVVSDGTE KKAHYYYLEWRNYAGSDNGLKAGKGPVYNTGLVVWYADDSFKDNWVGVHPGEGFLGVVDSHPEAFVGNLNGKPTYGNTGM QIADAAFSFDQTPAWSVNSLTRGQFNYSGLHGVTTFDDSKVYSNNQIADAGRKVPNLGLKFQVVGQADDKSAGAVWIKR
Specific function: Neutral metalloprotease that is secreted to degrade antibacterial proteins produced by the insect host for its defense (attacins and cecropins). Probably degrades some unknown crucial protein(s) too, since it is toxic when injected to insect larvae [H]
COG id: COG4412
COG function: function code S; Uncharacterized protein conserved in bacteria
Gene ontology:
Cell location: Secreted [H]
Metaboloic importance: NA
Operon status: Not Known
Operon components: None
Similarity: Belongs to the peptidase M6 family [H]
Homologues:
None
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR012300 - InterPro: IPR008757 [H]
Pfam domain/function: PF05547 Peptidase_M6 [H]
EC number: NA
Molecular weight: Translated: 87959; Mature: 87959
Theoretical pI: Translated: 5.68; Mature: 5.68
Prosite motif: PS00013 PROKAR_LIPOPROTEIN ; PS00142 ZINC_PROTEASE
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.3 %Cys (Translated Protein) 1.5 %Met (Translated Protein) 1.8 %Cys+Met (Translated Protein) 0.3 %Cys (Mature Protein) 1.5 %Met (Mature Protein) 1.8 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MRRKAPLKVLSSLAIAAIIGCTSVMSAPLAYAETPAKEKENVSTTPIDYNLIQEDRLAEA CCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHH LKERGTINPASSKEETKKAVEKYIEKKQGDQANKEILPADTAKEASDFVKKVKEKKMEEK HHHCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHH EKVKKPEKNVSPEQKPEPNKKQLNGQVPTSKAKQAPYKGSVRTDKVLVLLVEFSDYKHNN HHHCCCCCCCCCCCCCCCCHHHCCCCCCCCHHHCCCCCCCCCCCEEEEEEEEECCCCCCC IDQTPGYMYSNDFSREHYQKMLFGNEPYTLFDGSKVKTFKQYYEEQSGGSYTTDGYVTEW CCCCCCEEECCCCCHHHHHHHHCCCCCEEEECCCHHHHHHHHHHHHCCCCCCCCCEEEEE LTVPGKASDYGADGSSGHDNKGPKGARDLVKEALHAAAEKGLDLSQFDQFDRYDTNSDGN EECCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCCCC QNEPDGVIDHLMVIHAGVGQEAGGGKLGDDAIWSHRSKLAIDPVAIEGTKSKVDYFGGKV CCCCHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHCCCCEEECCEEECCCCHHHHHCCCEE AAHDYTIEPEDGAVGVFAHEFGHDLGLPDEYDTKYTGTGSPVEAWSLMSGGSWTGKIAGT EECCEEECCCCCEEEEEEHHHCCCCCCCCCCCCCCCCCCCCHHHHEECCCCCEEEEECCC EPTSFSPQNKDFLQKNMGGNWAKILEVDYDKIKRGVGVPTYIDQSVTKSNRPGVVRVNLP CCCCCCCCCHHHHHHCCCCCEEEEEECCHHHHHHCCCCCHHHHHHHHCCCCCCEEEEECC GKSVETIKPEFGKHAYYSTRGDDMHTTLETPFFDLTKGTNAKFDYKANYELEAECDFVEV CCCCHHCCCCCCCCCEEECCCCCCEEECCCCCEEECCCCCCEEEEECCCEEECCCCEEEE HAVTEDGTKTLIDRLGEKVVQGDKDTTDGKWIDKSYDLSQFKGKKVKLQFDYITDPAVTY EEECCCCHHHHHHHHHHHHHCCCCCCCCCCEECCCCCHHHCCCCEEEEEEEEECCCCEEE KGFAMDHVNVTVDGQVVFSDDAEGQSKMNLNGFVVSDGTEKKAHYYYLEWRNYAGSDNGL CCEEEEEEEEEECCEEEECCCCCCCCEECCCEEEEECCCCCCEEEEEEEEECCCCCCCCC KAGKGPVYNTGLVVWYADDSFKDNWVGVHPGEGFLGVVDSHPEAFVGNLNGKPTYGNTGM CCCCCCCEECCEEEEEECCCCCCCEEEECCCCCCEEEECCCCCCEEECCCCCCCCCCCCC QIADAAFSFDQTPAWSVNSLTRGQFNYSGLHGVTTFDDSKVYSNNQIADAGRKVPNLGLK EEHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCEEECCCCCCCCCCCHHHHCCCCCCCCEE FQVVGQADDKSAGAVWIKR EEEEECCCCCCCCEEEEEC >Mature Secondary Structure MRRKAPLKVLSSLAIAAIIGCTSVMSAPLAYAETPAKEKENVSTTPIDYNLIQEDRLAEA CCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHH LKERGTINPASSKEETKKAVEKYIEKKQGDQANKEILPADTAKEASDFVKKVKEKKMEEK HHHCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHH EKVKKPEKNVSPEQKPEPNKKQLNGQVPTSKAKQAPYKGSVRTDKVLVLLVEFSDYKHNN HHHCCCCCCCCCCCCCCCCHHHCCCCCCCCHHHCCCCCCCCCCCEEEEEEEEECCCCCCC IDQTPGYMYSNDFSREHYQKMLFGNEPYTLFDGSKVKTFKQYYEEQSGGSYTTDGYVTEW CCCCCCEEECCCCCHHHHHHHHCCCCCEEEECCCHHHHHHHHHHHHCCCCCCCCCEEEEE LTVPGKASDYGADGSSGHDNKGPKGARDLVKEALHAAAEKGLDLSQFDQFDRYDTNSDGN EECCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCCCC QNEPDGVIDHLMVIHAGVGQEAGGGKLGDDAIWSHRSKLAIDPVAIEGTKSKVDYFGGKV CCCCHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHCCCCEEECCEEECCCCHHHHHCCCEE AAHDYTIEPEDGAVGVFAHEFGHDLGLPDEYDTKYTGTGSPVEAWSLMSGGSWTGKIAGT EECCEEECCCCCEEEEEEHHHCCCCCCCCCCCCCCCCCCCCHHHHEECCCCCEEEEECCC EPTSFSPQNKDFLQKNMGGNWAKILEVDYDKIKRGVGVPTYIDQSVTKSNRPGVVRVNLP CCCCCCCCCHHHHHHCCCCCEEEEEECCHHHHHHCCCCCHHHHHHHHCCCCCCEEEEECC GKSVETIKPEFGKHAYYSTRGDDMHTTLETPFFDLTKGTNAKFDYKANYELEAECDFVEV CCCCHHCCCCCCCCCEEECCCCCCEEECCCCCEEECCCCCCEEEEECCCEEECCCCEEEE HAVTEDGTKTLIDRLGEKVVQGDKDTTDGKWIDKSYDLSQFKGKKVKLQFDYITDPAVTY EEECCCCHHHHHHHHHHHHHCCCCCCCCCCEECCCCCHHHCCCCEEEEEEEEECCCCEEE KGFAMDHVNVTVDGQVVFSDDAEGQSKMNLNGFVVSDGTEKKAHYYYLEWRNYAGSDNGL CCEEEEEEEEEECCEEEECCCCCCCCEECCCEEEEECCCCCCEEEEEEEEECCCCCCCCC KAGKGPVYNTGLVVWYADDSFKDNWVGVHPGEGFLGVVDSHPEAFVGNLNGKPTYGNTGM CCCCCCCEECCEEEEEECCCCCCCEEEECCCCCCEEEECCCCCCEEECCCCCCCCCCCCC QIADAAFSFDQTPAWSVNSLTRGQFNYSGLHGVTTFDDSKVYSNNQIADAGRKVPNLGLK EEHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCEEECCCCCCCCCCCHHHHCCCCCCCCEE FQVVGQADDKSAGAVWIKR EEEEECCCCCCCCEEEEEC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 9.0
TargetDB status: NA
Availability: NA
References: 2089225; 6421577 [H]