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The map label for this gene is glpT [H]

Identifier: 218901857

GI number: 218901857

Start: 692813

End: 694162

Strand: Reverse

Name: glpT [H]

Synonym: BCAH820_0718

Alternate gene names: 218901857

Gene position: 694162-692813 (Counterclockwise)

Preceding gene: 218901868

Following gene: 218901856

Centisome position: 13.09

GC content: 39.33

Gene sequence:

>1350_bases
ATGTTTTTTACACAATTCTTTAAACCTGCGCCCCACGCGGAACGCTTACCAGCTGACCGCGTTGACAGTGAATACCGTAA
ACTACGTTTACAAGTATTCTTAGGTATCTTCATCGGCTATGCAGGTTATTACTTTGTTCGAAAAAACTTTTCACTAGCAA
TGCCATACTTAATTGAACAAGGCTTTAGTAAAGGGGAACTTGGGGTTATCCTTTCAGCAGTTTCTATCGCTTACGGATTA
AGTAAATTTCTTATGGGTATCGTATCCGATCGTTGTAATCCTCGCTACTTTTTAGCAGCTGGGCTATTTTTATCAGGTAT
CATTAATATTATTTTCGGCTCATTTTCTTTCATTACAACGAGTATTATACTTATGTTTGTACTTCAGTTTTTAAATGGAT
GGGTACAAGGTATGGGATGGCCTCCTTGTGGTCGTACAATGGTTCACTGGTTCTCTATTAGTGAACGTGGTACAAAAATG
TCTATTTGGAACGTCGCTCATAACGTCGGCGGAGCGCTTATGCCTTCTCTTGTAACATTAGGTTTATACTTCTTCGCAGA
TGACTGGAAAAGTATTTTTTACTTCCCAGGTATTCTTTCAATTTTAGTTGGTATTTATGTATTAATTACGATGAAAGATA
CGCCTCAATCTTGCGGATTGCCTTCTATTGAAGAACATACTGGAGAATATCCACCAGATGAGAAGATAAAAGATCGTGAA
CGTGAACTTTCAGCAAAGGAAATTTTATTTAAATACGTACTAAACAATAAATTTTTATGGTACATCGCGATTGCGAACGT
TTTCGTATATTTCGTACGTTACGGTGTTGTAGACTGGGCTCCTACTTATTTAGTAGAAGAAAAAAGCTTTACTCATAGTA
GTTCACGTACAGCTTATGCTCTATATGAATGGGCTGGTATTCCAGGTACACTTCTTTGTGGCTGGATGAGTGATAAACTA
TTTAAAGGACGCCGCGCACCTGCTGGTATTTTATTTATGGTTGGTGTATTTATCGCCGTTCTTGTGTACTGGCTAAACCC
TCCTGGTAATCCAATGGTTGATAGTATCGCACTTGTTGCAATTGGATTTTTAATTTACGGACCTGTTATGTTAATTGGTC
TACACGCTCTTGACTTAGCACCAAAGAAAGCGGCTGGAACTGCAGCTGGATTAACTGGCTTCTTCGGTTACTTAGGCGGA
GCAGCTTTCGCTAGTGCCGCTATGGGCTTTATCGTCGATGCATTCGGATGGGATGGGGGATTCATCTTATTACTTGCATC
TTGTGTACTTGCAATGTTCTTCCTTGCTCTTACTTTAAAGACAGGGTCAGTAAAACAAAAGCAAGCTTAA

Upstream 100 bases:

>100_bases
TATGAATCATAAAAAAGGAAACTTTTTTATATTTCATGGCCTTTTTATATTCTCTCTGACTTACGACACTTCGAATTAAT
TTGGGGAGGATTTTCATTTT

Downstream 100 bases:

>100_bases
GCACTAATATTATTCTTATCAAAAAAAGAGAGGCTGTTCTTTCGAGAACGCCTCTCTTTTTTCTACATATAATACTTTTT
TCTTACAAAAGATTTATTTC

Product: glycerol-3-phosphate transporter

Products: Proton [Cytoplasm]; glycerol-3-phosphate [Cytoplasm] [C]

Alternate protein names: G-3-P transporter; G-3-P permease [H]

Number of amino acids: Translated: 449; Mature: 449

Protein sequence:

>449_residues
MFFTQFFKPAPHAERLPADRVDSEYRKLRLQVFLGIFIGYAGYYFVRKNFSLAMPYLIEQGFSKGELGVILSAVSIAYGL
SKFLMGIVSDRCNPRYFLAAGLFLSGIINIIFGSFSFITTSIILMFVLQFLNGWVQGMGWPPCGRTMVHWFSISERGTKM
SIWNVAHNVGGALMPSLVTLGLYFFADDWKSIFYFPGILSILVGIYVLITMKDTPQSCGLPSIEEHTGEYPPDEKIKDRE
RELSAKEILFKYVLNNKFLWYIAIANVFVYFVRYGVVDWAPTYLVEEKSFTHSSSRTAYALYEWAGIPGTLLCGWMSDKL
FKGRRAPAGILFMVGVFIAVLVYWLNPPGNPMVDSIALVAIGFLIYGPVMLIGLHALDLAPKKAAGTAAGLTGFFGYLGG
AAFASAAMGFIVDAFGWDGGFILLLASCVLAMFFLALTLKTGSVKQKQA

Sequences:

>Translated_449_residues
MFFTQFFKPAPHAERLPADRVDSEYRKLRLQVFLGIFIGYAGYYFVRKNFSLAMPYLIEQGFSKGELGVILSAVSIAYGL
SKFLMGIVSDRCNPRYFLAAGLFLSGIINIIFGSFSFITTSIILMFVLQFLNGWVQGMGWPPCGRTMVHWFSISERGTKM
SIWNVAHNVGGALMPSLVTLGLYFFADDWKSIFYFPGILSILVGIYVLITMKDTPQSCGLPSIEEHTGEYPPDEKIKDRE
RELSAKEILFKYVLNNKFLWYIAIANVFVYFVRYGVVDWAPTYLVEEKSFTHSSSRTAYALYEWAGIPGTLLCGWMSDKL
FKGRRAPAGILFMVGVFIAVLVYWLNPPGNPMVDSIALVAIGFLIYGPVMLIGLHALDLAPKKAAGTAAGLTGFFGYLGG
AAFASAAMGFIVDAFGWDGGFILLLASCVLAMFFLALTLKTGSVKQKQA
>Mature_449_residues
MFFTQFFKPAPHAERLPADRVDSEYRKLRLQVFLGIFIGYAGYYFVRKNFSLAMPYLIEQGFSKGELGVILSAVSIAYGL
SKFLMGIVSDRCNPRYFLAAGLFLSGIINIIFGSFSFITTSIILMFVLQFLNGWVQGMGWPPCGRTMVHWFSISERGTKM
SIWNVAHNVGGALMPSLVTLGLYFFADDWKSIFYFPGILSILVGIYVLITMKDTPQSCGLPSIEEHTGEYPPDEKIKDRE
RELSAKEILFKYVLNNKFLWYIAIANVFVYFVRYGVVDWAPTYLVEEKSFTHSSSRTAYALYEWAGIPGTLLCGWMSDKL
FKGRRAPAGILFMVGVFIAVLVYWLNPPGNPMVDSIALVAIGFLIYGPVMLIGLHALDLAPKKAAGTAAGLTGFFGYLGG
AAFASAAMGFIVDAFGWDGGFILLLASCVLAMFFLALTLKTGSVKQKQA

Specific function: Responsible for glycerol-3-phosphate uptake [H]

COG id: COG2271

COG function: function code G; Sugar phosphate permease

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. Organophosphate:Pi antiporter (OPA) (TC 2.A.1.4) family [H]

Homologues:

Organism=Homo sapiens, GI256219598, Length=438, Percent_Identity=28.9954337899543, Blast_Score=180, Evalue=2e-45,
Organism=Homo sapiens, GI4503847, Length=438, Percent_Identity=28.9954337899543, Blast_Score=180, Evalue=2e-45,
Organism=Homo sapiens, GI256219483, Length=438, Percent_Identity=28.9954337899543, Blast_Score=180, Evalue=2e-45,
Organism=Homo sapiens, GI256219543, Length=460, Percent_Identity=27.6086956521739, Blast_Score=173, Evalue=2e-43,
Organism=Homo sapiens, GI256219564, Length=369, Percent_Identity=26.5582655826558, Blast_Score=126, Evalue=4e-29,
Organism=Homo sapiens, GI38093649, Length=470, Percent_Identity=25.7446808510638, Blast_Score=102, Evalue=8e-22,
Organism=Homo sapiens, GI223717983, Length=470, Percent_Identity=25.7446808510638, Blast_Score=102, Evalue=1e-21,
Organism=Homo sapiens, GI46361976, Length=463, Percent_Identity=23.9740820734341, Blast_Score=95, Evalue=2e-19,
Organism=Homo sapiens, GI49619231, Length=416, Percent_Identity=22.8365384615385, Blast_Score=77, Evalue=3e-14,
Organism=Homo sapiens, GI14150047, Length=330, Percent_Identity=23.030303030303, Blast_Score=68, Evalue=2e-11,
Organism=Escherichia coli, GI1788573, Length=442, Percent_Identity=60.8597285067873, Blast_Score=557, Evalue=1e-160,
Organism=Escherichia coli, GI87082310, Length=436, Percent_Identity=37.8440366972477, Blast_Score=293, Evalue=1e-80,
Organism=Escherichia coli, GI2367259, Length=459, Percent_Identity=32.8976034858388, Blast_Score=211, Evalue=6e-56,
Organism=Escherichia coli, GI2367379, Length=420, Percent_Identity=24.5238095238095, Blast_Score=98, Evalue=1e-21,
Organism=Escherichia coli, GI87082320, Length=439, Percent_Identity=23.9179954441913, Blast_Score=81, Evalue=1e-16,
Organism=Escherichia coli, GI1789515, Length=396, Percent_Identity=25.2525252525253, Blast_Score=80, Evalue=4e-16,
Organism=Escherichia coli, GI1789152, Length=443, Percent_Identity=23.4762979683973, Blast_Score=73, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI17564202, Length=428, Percent_Identity=26.8691588785047, Blast_Score=98, Evalue=7e-21,
Organism=Caenorhabditis elegans, GI17564204, Length=365, Percent_Identity=27.9452054794521, Blast_Score=96, Evalue=3e-20,
Organism=Caenorhabditis elegans, GI133901854, Length=438, Percent_Identity=25.1141552511416, Blast_Score=95, Evalue=9e-20,
Organism=Caenorhabditis elegans, GI133901856, Length=438, Percent_Identity=25.1141552511416, Blast_Score=94, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI133930953, Length=460, Percent_Identity=23.0434782608696, Blast_Score=88, Evalue=7e-18,
Organism=Caenorhabditis elegans, GI17542316, Length=453, Percent_Identity=24.2825607064018, Blast_Score=87, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI17561094, Length=399, Percent_Identity=22.0551378446115, Blast_Score=69, Evalue=7e-12,
Organism=Caenorhabditis elegans, GI17539138, Length=326, Percent_Identity=23.9263803680982, Blast_Score=66, Evalue=3e-11,
Organism=Drosophila melanogaster, GI24656866, Length=470, Percent_Identity=23.1914893617021, Blast_Score=100, Evalue=2e-21,
Organism=Drosophila melanogaster, GI45550478, Length=470, Percent_Identity=23.1914893617021, Blast_Score=100, Evalue=2e-21,
Organism=Drosophila melanogaster, GI24656861, Length=470, Percent_Identity=23.1914893617021, Blast_Score=100, Evalue=3e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005267
- InterPro:   IPR000849
- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196
- InterPro:   IPR021159 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 49788; Mature: 49788

Theoretical pI: Translated: 9.09; Mature: 9.09

Prosite motif: PS50850 MFS ; PS00942 GLPT

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHHHHHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure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HHHHHHHHHHHHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; glycerol-3-phosphate [Periplasm] [C]

Specific reaction: Proton [Periplasm] + glycerol-3-phosphate [Periplasm] = Proton [Cytoplasm] + glycerol-3-phosphate [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8012593; 9384377 [H]