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The map label for this gene is treR [H]

Identifier: 218901824

GI number: 218901824

Start: 660292

End: 661002

Strand: Direct

Name: treR [H]

Synonym: BCAH820_0685

Alternate gene names: 218901824

Gene position: 660292-661002 (Clockwise)

Preceding gene: 218901822

Following gene: 218901825

Centisome position: 12.45

GC content: 33.76

Gene sequence:

>711_bases
ATGATGAGTAAGTATGAACAAATTTATACAGCAATCAGCAAGTCTATTGATAATAAACAATTAAAAGAGGGATGCAAAAT
CCCATCAGAAACTGAATTAATGAAACAGTATGAAGCGAGCCGTGGTACTGTAAGAAAAGCAGTGGATTTATTACAAGAGC
GTGGATATGTTCAAAAGATACATGGAAAAGGTGTTTTTGTTTTAAAGCGTAAAAACATTGAATTCAACTTTGGTGGCATT
GTAAGTTTCCAAGAAGAAAATGAACGTTTAGGGCGCCATTGTATTACAGAAGTCGTGGAAATAGAGAAAATAAAAGCGAC
AAAAGAGATTGCAAAGCTATTAAATGTGAAAGAGAAAACAGAAATAGATCATATTAAACGCGTACGAAATATTGATGGAG
AAAAAGTAATTTTGGATATTAATCATTTTGTATCGGAACATATCCCTGGATTAACGATTGAAATTGCAGCGGGGTCCATT
TATAAATACATAGAGAAAGAATTAGGTCTTCATATTAGTTACTCACAGAGGGTAATTGAGGTGCAGCCATGTACAGAGGA
CGATAGAAAGTATTTAGATTTAAATGGAACAGATTATGTTGTCGTTGTGAAAAACTTTACGCATTTTTATGATGGAAGTC
AGTTCGAATATACAGAATCACGTCACCGCTTAGATATTTTTCATTTTTCGGATGTGGCGCGGAGAAAATAA

Upstream 100 bases:

>100_bases
CTGTATTTTTCCTATACTGGAAAATAAGTGAGAGATTGGCAGAAGAGTGTAGCATGGTATAATACATATAGAATTAGAAG
GTGACAAGGGGCTATTGTAG

Downstream 100 bases:

>100_bases
GGAGATGGGACGAAATAACGTTTCATCTCTTTTTTTATAAAAAAAATCACAAACTCGTATATACGAGTGTTGACTAACTT
ATATATACGAGTTAATATGT

Product: trehalose operon repressor

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 236; Mature: 236

Protein sequence:

>236_residues
MMSKYEQIYTAISKSIDNKQLKEGCKIPSETELMKQYEASRGTVRKAVDLLQERGYVQKIHGKGVFVLKRKNIEFNFGGI
VSFQEENERLGRHCITEVVEIEKIKATKEIAKLLNVKEKTEIDHIKRVRNIDGEKVILDINHFVSEHIPGLTIEIAAGSI
YKYIEKELGLHISYSQRVIEVQPCTEDDRKYLDLNGTDYVVVVKNFTHFYDGSQFEYTESRHRLDIFHFSDVARRK

Sequences:

>Translated_236_residues
MMSKYEQIYTAISKSIDNKQLKEGCKIPSETELMKQYEASRGTVRKAVDLLQERGYVQKIHGKGVFVLKRKNIEFNFGGI
VSFQEENERLGRHCITEVVEIEKIKATKEIAKLLNVKEKTEIDHIKRVRNIDGEKVILDINHFVSEHIPGLTIEIAAGSI
YKYIEKELGLHISYSQRVIEVQPCTEDDRKYLDLNGTDYVVVVKNFTHFYDGSQFEYTESRHRLDIFHFSDVARRK
>Mature_236_residues
MMSKYEQIYTAISKSIDNKQLKEGCKIPSETELMKQYEASRGTVRKAVDLLQERGYVQKIHGKGVFVLKRKNIEFNFGGI
VSFQEENERLGRHCITEVVEIEKIKATKEIAKLLNVKEKTEIDHIKRVRNIDGEKVILDINHFVSEHIPGLTIEIAAGSI
YKYIEKELGLHISYSQRVIEVQPCTEDDRKYLDLNGTDYVVVVKNFTHFYDGSQFEYTESRHRLDIFHFSDVARRK

Specific function: Repressor for the trehalose operon (treP and treA). Binds trehalose-6-phosphate, which probably acts as an inducer [H]

COG id: COG2188

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH gntR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1786950, Length=236, Percent_Identity=29.2372881355932, Blast_Score=88, Evalue=4e-19,
Organism=Escherichia coli, GI1790540, Length=231, Percent_Identity=24.2424242424242, Blast_Score=84, Evalue=1e-17,
Organism=Escherichia coli, GI1790118, Length=168, Percent_Identity=27.3809523809524, Blast_Score=74, Evalue=6e-15,
Organism=Escherichia coli, GI87082252, Length=172, Percent_Identity=27.3255813953488, Blast_Score=69, Evalue=3e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000524
- InterPro:   IPR012770
- InterPro:   IPR011663
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00392 GntR; PF07702 UTRA [H]

EC number: NA

Molecular weight: Translated: 27474; Mature: 27474

Theoretical pI: Translated: 8.09; Mature: 8.09

Prosite motif: PS50949 HTH_GNTR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMSKYEQIYTAISKSIDNKQLKEGCKIPSETELMKQYEASRGTVRKAVDLLQERGYVQKI
CCCHHHHHHHHHHHCCCHHHHHHHCCCCCHHHHHHHHHHCCCHHHHHHHHHHHCCCEEEE
HGKGVFVLKRKNIEFNFGGIVSFQEENERLGRHCITEVVEIEKIKATKEIAKLLNVKEKT
CCCCEEEEEECCEEEECCCEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHH
EIDHIKRVRNIDGEKVILDINHFVSEHIPGLTIEIAAGSIYKYIEKELGLHISYSQRVIE
HHHHHHHHHCCCCCEEEEEHHHHHHHCCCCEEEEEECCHHHHHHHHHHCEEEECCCEEEE
VQPCTEDDRKYLDLNGTDYVVVVKNFTHFYDGSQFEYTESRHRLDIFHFSDVARRK
EECCCCCCCEEEECCCCEEEEEEECCHHHCCCCCEEECCCCCEEEEEEHHHHHHCC
>Mature Secondary Structure
MMSKYEQIYTAISKSIDNKQLKEGCKIPSETELMKQYEASRGTVRKAVDLLQERGYVQKI
CCCHHHHHHHHHHHCCCHHHHHHHCCCCCHHHHHHHHHHCCCHHHHHHHHHHHCCCEEEE
HGKGVFVLKRKNIEFNFGGIVSFQEENERLGRHCITEVVEIEKIKATKEIAKLLNVKEKT
CCCCEEEEEECCEEEECCCEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHH
EIDHIKRVRNIDGEKVILDINHFVSEHIPGLTIEIAAGSIYKYIEKELGLHISYSQRVIE
HHHHHHHHHCCCCCEEEEEHHHHHHHCCCCEEEEEECCHHHHHHHHHHCEEEECCCEEEE
VQPCTEDDRKYLDLNGTDYVVVVKNFTHFYDGSQFEYTESRHRLDIFHFSDVARRK
EECCCCCCCEEEECCCCEEEEEEECCHHHCCCCCEEECCCCCEEEEEEHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8917076; 8969503; 9384377; 7651129; 8755887 [H]