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The map label for this gene is lexA1 [H]

Identifier: 218901745

GI number: 218901745

Start: 565497

End: 565745

Strand: Reverse

Name: lexA1 [H]

Synonym: BCAH820_0606

Alternate gene names: 218901745

Gene position: 565745-565497 (Counterclockwise)

Preceding gene: 218901749

Following gene: 218901744

Centisome position: 10.67

GC content: 37.35

Gene sequence:

>249_bases
ATGAAACCATTAACAAGCAGACAATCTCAAATACTAACATTCATCCAAGAAAAAGTTATAGAAAATGGATATCCTCCTAC
TGTTAGGGAAATCTGTAAAGCGACTGGACTCGCTTCTAGTTCCACAGTACATGGGCATTTAATGCACTTAGAAGAGAAAG
GGTATATTCACCGTGCCCCATCTAAGTCACGTACAATCAAAATTTTAAAAGGAGGATTCGAACATGATTACCAATCCAAT
AGCATCTGA

Upstream 100 bases:

>100_bases
CTATTATTCCAAACATAAACAGAACATACGTTTGATTATTTCCCCTCTATTTGCTATGATGTAGTAAAATATTTCCTAAA
TCAAGAGAGGATATCACCTA

Downstream 100 bases:

>100_bases
AAAGGACAAGTTGATTAGAGAAATGATTTCGGCTCAAAAACAAAGTGGGAATCTATTATACCACCTCAATAACCAGGTAG
AAATTGCGCATCTCAATTAT

Product: LexA DNA binding domain protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 82; Mature: 82

Protein sequence:

>82_residues
MKPLTSRQSQILTFIQEKVIENGYPPTVREICKATGLASSSTVHGHLMHLEEKGYIHRAPSKSRTIKILKGGFEHDYQSN
SI

Sequences:

>Translated_82_residues
MKPLTSRQSQILTFIQEKVIENGYPPTVREICKATGLASSSTVHGHLMHLEEKGYIHRAPSKSRTIKILKGGFEHDYQSN
SI
>Mature_82_residues
MKPLTSRQSQILTFIQEKVIENGYPPTVREICKATGLASSSTVHGHLMHLEEKGYIHRAPSKSRTIKILKGGFEHDYQSN
SI

Specific function: Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, recA interacts with lexA causing an autocatalytic cleavage which disrupts the DNA-binding part of lexA, lea

COG id: COG1974

COG function: function code KT; SOS-response transcriptional repressors (RecA-mediated autopeptidases)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S24 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006199
- InterPro:   IPR006200
- InterPro:   IPR006197
- InterPro:   IPR019759
- InterPro:   IPR015927
- InterPro:   IPR011056
- InterPro:   IPR011991 [H]

Pfam domain/function: PF01726 LexA_DNA_bind; PF00717 Peptidase_S24 [H]

EC number: =3.4.21.88 [H]

Molecular weight: Translated: 9222; Mature: 9222

Theoretical pI: Translated: 9.94; Mature: 9.94

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKPLTSRQSQILTFIQEKVIENGYPPTVREICKATGLASSSTVHGHLMHLEEKGYIHRAP
CCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCCHHEEEECCCCCEECCC
SKSRTIKILKGGFEHDYQSNSI
CCCCEEEEEECCCCCCCCCCCC
>Mature Secondary Structure
MKPLTSRQSQILTFIQEKVIENGYPPTVREICKATGLASSSTVHGHLMHLEEKGYIHRAP
CCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCCHHEEEECCCCCEECCC
SKSRTIKILKGGFEHDYQSNSI
CCCCEEEEEECCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA