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The map label for this gene is pbuG [H]

Identifier: 218901461

GI number: 218901461

Start: 263437

End: 264762

Strand: Direct

Name: pbuG [H]

Synonym: BCAH820_0295

Alternate gene names: 218901461

Gene position: 263437-264762 (Clockwise)

Preceding gene: 218901460

Following gene: 218901462

Centisome position: 4.97

GC content: 40.05

Gene sequence:

>1326_bases
ATGAAACGCTATTTTCAGTTTGATGAACTCGGCACGAATTATAAAACAGAGTTCATAGCAGGTTTAACGACATTTCTATC
TATGGCTTACGTACTATTTGTCAATCCTGCTACGCTGTCACTTGGGAATGTTAAAGGGTTACCAGCAGGTACAGGAATGG
ATCCAGGTGCAGTATTCGTTGCTACAGCATTAGCAGCAGCGATCGGTTCGTTAATTATGGGGGTTTTCGCGAAGTATCCG
ATTGCTTTGGCGCCGGGTATGGGAATTAACGCGTTCTTTGCTTATACAGCAGTGTTAACGATGGGTATTCCGTGGCAAAC
AGCAATTGCTGGAACGTTAATGTCAGGTATTATCTTTATTATTCTTACAGCTTCAGGTATTCGTGAAAAAATCATTAATG
CAATTCCATCAGAGTTAAAGTTTGCAGTAGCGGCAGGTATCGGATTATTCATTGCTTTCCTTGGATTCCAAAATGCTGGA
ATTATCGTGAAAAATGATGCTGTTCTTGTTGGGTTGGGGGACTTAACAAAGGGCACAACGTTACTAGCAATCTTCGGAGT
TGTTACGACAATTATCTTCATGATTAAGAAAGTAAATGGTGCAGTATTTTACGGTATGATTCTTACAGCAATCTTAGGAG
TAGCAACAGGATTAATTGATACTCCGAAAGCTGTAGTGGGAGCAATACCGAGTCTAGAACCAACGTTCGGTGTGGCGTTA
ACGCACTTCGGAGATATTTTCACTGTTCAAATGGTGATTGTTATTATAACGTTCTTCTTTATCGATTTCTTTGATACAGC
AGGTACACTTGTAGCGGTTGCGAATCAAGCTGGATTAATGAAGAACAATAAATTACCACGTGCAGGAAAAGCATTATTTG
CAGATGCGATTGCAACTGTAATTGGTGCGATCTTAGGTACATCAACAACAACGTCTTATATTGAATCTTCTGCAGGGGTA
GCAGCGGGTGGACGTTCTGGATTTACAGCAGTTGTAACAGCAGGATTCTTCTTACTGGCACTATTCTTCTCGCCATTACT
AAGTGTTGTAACGCCAGCTGTAACGGCACCAGCTTTAATTATTGTAGGAATCTTGATGGTTTCTTCCTTAGGGGAAATTG
ATTGGAAGAAATTCGAGATTGCAGTACCAGCATTCTTTACAATTATCTCTATGCCACTTACGTATAGTATCGCAACGGGA
ATTGCGATTGGATTTATCTTCTATCCAATTACAATGGTAGTAAGCGGTCGTCGTAAAGAGATTCATCCGATTATGTATGT
TATGGGAGTTTTATTCGTACTATATTTCATCTACGTTCGTAAATAA

Upstream 100 bases:

>100_bases
ACGCTTCCATGTATATGCAATGGAAGCCTTTTTTATTTTTAATAGATAAAAGAGGGCTAGGGGATTACGGCGAGTAATCA
TATAACGGGGGAAACGTAAG

Downstream 100 bases:

>100_bases
AAGGGGTTTTTTGAAAGGTCTAGACTTAAGGGGAGTCTAGACCTTTTTTGCGTCTTCAGAAAAACTTAAGGATTTCCGAG
CGTTTTTCTTCAGAAGTTTT

Product: xanthine/uracil permease family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 441; Mature: 441

Protein sequence:

>441_residues
MKRYFQFDELGTNYKTEFIAGLTTFLSMAYVLFVNPATLSLGNVKGLPAGTGMDPGAVFVATALAAAIGSLIMGVFAKYP
IALAPGMGINAFFAYTAVLTMGIPWQTAIAGTLMSGIIFIILTASGIREKIINAIPSELKFAVAAGIGLFIAFLGFQNAG
IIVKNDAVLVGLGDLTKGTTLLAIFGVVTTIIFMIKKVNGAVFYGMILTAILGVATGLIDTPKAVVGAIPSLEPTFGVAL
THFGDIFTVQMVIVIITFFFIDFFDTAGTLVAVANQAGLMKNNKLPRAGKALFADAIATVIGAILGTSTTTSYIESSAGV
AAGGRSGFTAVVTAGFFLLALFFSPLLSVVTPAVTAPALIIVGILMVSSLGEIDWKKFEIAVPAFFTIISMPLTYSIATG
IAIGFIFYPITMVVSGRRKEIHPIMYVMGVLFVLYFIYVRK

Sequences:

>Translated_441_residues
MKRYFQFDELGTNYKTEFIAGLTTFLSMAYVLFVNPATLSLGNVKGLPAGTGMDPGAVFVATALAAAIGSLIMGVFAKYP
IALAPGMGINAFFAYTAVLTMGIPWQTAIAGTLMSGIIFIILTASGIREKIINAIPSELKFAVAAGIGLFIAFLGFQNAG
IIVKNDAVLVGLGDLTKGTTLLAIFGVVTTIIFMIKKVNGAVFYGMILTAILGVATGLIDTPKAVVGAIPSLEPTFGVAL
THFGDIFTVQMVIVIITFFFIDFFDTAGTLVAVANQAGLMKNNKLPRAGKALFADAIATVIGAILGTSTTTSYIESSAGV
AAGGRSGFTAVVTAGFFLLALFFSPLLSVVTPAVTAPALIIVGILMVSSLGEIDWKKFEIAVPAFFTIISMPLTYSIATG
IAIGFIFYPITMVVSGRRKEIHPIMYVMGVLFVLYFIYVRK
>Mature_441_residues
MKRYFQFDELGTNYKTEFIAGLTTFLSMAYVLFVNPATLSLGNVKGLPAGTGMDPGAVFVATALAAAIGSLIMGVFAKYP
IALAPGMGINAFFAYTAVLTMGIPWQTAIAGTLMSGIIFIILTASGIREKIINAIPSELKFAVAAGIGLFIAFLGFQNAG
IIVKNDAVLVGLGDLTKGTTLLAIFGVVTTIIFMIKKVNGAVFYGMILTAILGVATGLIDTPKAVVGAIPSLEPTFGVAL
THFGDIFTVQMVIVIITFFFIDFFDTAGTLVAVANQAGLMKNNKLPRAGKALFADAIATVIGAILGTSTTTSYIESSAGV
AAGGRSGFTAVVTAGFFLLALFFSPLLSVVTPAVTAPALIIVGILMVSSLGEIDWKKFEIAVPAFFTIISMPLTYSIATG
IAIGFIFYPITMVVSGRRKEIHPIMYVMGVLFVLYFIYVRK

Specific function: Involved in the uptake of the purine bases hypoxanthine and guanine [H]

COG id: COG2252

COG function: function code R; Permeases

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the xanthine/uracil permease family. AzgA purine transporter (TC 2.A.1.40) subfamily [H]

Homologues:

Organism=Escherichia coli, GI87082309, Length=446, Percent_Identity=41.4798206278027, Blast_Score=333, Evalue=1e-92,
Organism=Escherichia coli, GI1790150, Length=440, Percent_Identity=41.1363636363636, Blast_Score=321, Evalue=8e-89,
Organism=Escherichia coli, GI1790499, Length=446, Percent_Identity=34.5291479820628, Blast_Score=216, Evalue=2e-57,
Organism=Escherichia coli, GI48994909, Length=431, Percent_Identity=33.1786542923434, Blast_Score=195, Evalue=4e-51,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006043 [H]

Pfam domain/function: PF00860 Xan_ur_permease [H]

EC number: NA

Molecular weight: Translated: 46364; Mature: 46364

Theoretical pI: Translated: 9.74; Mature: 9.74

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKRYFQFDELGTNYKTEFIAGLTTFLSMAYVLFVNPATLSLGNVKGLPAGTGMDPGAVFV
CCCCCCHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCCCCCCCCCCCCHHHHH
ATALAAAIGSLIMGVFAKYPIALAPGMGINAFFAYTAVLTMGIPWQTAIAGTLMSGIIFI
HHHHHHHHHHHHHHHHHHCCCEECCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHH
ILTASGIREKIINAIPSELKFAVAAGIGLFIAFLGFQNAGIIVKNDAVLVGLGDLTKGTT
HHCCCHHHHHHHHHCHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCEEEEECCCCCCCHH
LLAIFGVVTTIIFMIKKVNGAVFYGMILTAILGVATGLIDTPKAVVGAIPSLEPTFGVAL
HHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCHHHHHCCCCCCCHHHHHH
THFGDIFTVQMVIVIITFFFIDFFDTAGTLVAVANQAGLMKNNKLPRAGKALFADAIATV
HHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHH
IGAILGTSTTTSYIESSAGVAAGGRSGFTAVVTAGFFLLALFFSPLLSVVTPAVTAPALI
HHHHHCCCCHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IVGILMVSSLGEIDWKKFEIAVPAFFTIISMPLTYSIATGIAIGFIFYPITMVVSGRRKE
HHHHHHHHHCCCCCCHHEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHH
IHPIMYVMGVLFVLYFIYVRK
HHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MKRYFQFDELGTNYKTEFIAGLTTFLSMAYVLFVNPATLSLGNVKGLPAGTGMDPGAVFV
CCCCCCHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCCCCCCCCCCCCHHHHH
ATALAAAIGSLIMGVFAKYPIALAPGMGINAFFAYTAVLTMGIPWQTAIAGTLMSGIIFI
HHHHHHHHHHHHHHHHHHCCCEECCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHH
ILTASGIREKIINAIPSELKFAVAAGIGLFIAFLGFQNAGIIVKNDAVLVGLGDLTKGTT
HHCCCHHHHHHHHHCHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCEEEEECCCCCCCHH
LLAIFGVVTTIIFMIKKVNGAVFYGMILTAILGVATGLIDTPKAVVGAIPSLEPTFGVAL
HHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCHHHHHCCCCCCCHHHHHH
THFGDIFTVQMVIVIITFFFIDFFDTAGTLVAVANQAGLMKNNKLPRAGKALFADAIATV
HHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHH
IGAILGTSTTTSYIESSAGVAAGGRSGFTAVVTAGFFLLALFFSPLLSVVTPAVTAPALI
HHHHHCCCCHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IVGILMVSSLGEIDWKKFEIAVPAFFTIISMPLTYSIATGIAIGFIFYPITMVVSGRRKE
HHHHHHHHHCCCCCCHHEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHH
IHPIMYVMGVLFVLYFIYVRK
HHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8969499; 9384377; 11591660 [H]