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The map label for this gene is moaA [C]

Identifier: 218884694

GI number: 218884694

Start: 1287239

End: 1288957

Strand: Reverse

Name: moaA [C]

Synonym: DKAM_1383

Alternate gene names: 218884694

Gene position: 1288957-1287239 (Counterclockwise)

Preceding gene: 218884699

Following gene: 218884692

Centisome position: 94.41

GC content: 44.44

Gene sequence:

>1719_bases
ATGTTTATAGACTACCTGGTGGGTGATTTGAGTATTCAGGAGTCATCAAAGAAGCCCGGTGAAATAGTTTACATCCTGCC
GAAGCTACATAGCGGCGAGGAAGTATTATCCCTTACAACAAGTGTTTGCCCATACTGCTACAGGGTTCTCCCAGCTGTAA
TAGTTGAGAGAGATGGGAAGGTATATATTAGAAGAATCTGCCCGGAACACGGTGAAATCGAGGAACTATACTACGGCGAT
GTAGATTTCTATAAGAGGGTTGTAAAGTACACTGAAGACGGGAGGGGGGCTAGACACATATACACACAGGTTAAAACACT
ATGTCCATTCAACTGTGGATTATGCCCGATGCATAAACAACATACGGCGCTGGTGAATATGGTTGTAACAAATAGATGTA
ACTTATCCTGCTGGTACTGCTTCTTTTACTCGGAGGCCTCGGGATACGTCTACGAGCCGAGACTGGATCAAATAAGGGAG
ATGGTTAGAAGCATTAAGAAGCAGGGTGTAACCGTTGCAATACAGTTGACTGGAGGGGAACCATTATTAAGGGAGGACCT
CGTCGACATCGTGAAGCTATTAAAGGAAGAGGGGGTAAGACACATACAGTTAAATACTAATGGGATAAGATTCGCCGAGC
TATATATAGAGGACCCAGTTAAAGCAGTCGAGTACGCTAGGGAGCTGAGAAGCAGCGGCGTAAACACAGTATACCTCAGC
TTCGACGGGGTAACGCCCGTAACAAACTGGAAGAACCACTGGGAGGTACCATACATACTTGAGACGTTCAGGAAGGCCGG
CATGACCAGTACTGTACTGGTTCCAACGGTTATTAAAGGCGTGAACACACATGAGCTCGGAGCTATAGTCAGGTTTGCTG
CTAAACACATGGATGTTATAAGAGCAGTGAACTTCCAGCCGGTGAGCCTCACTGGATACATGAAGAAGCATGAGAGGGAA
AAGTACAGGATAACAATACCAGAGGTAGTAAAGTTGATAGAGGAGCAGACCGATGGACAGGTAACCAGAGATGCATGGTT
CCCGATAAACGTTAGCGCATTATTCTCAAGGTTCATAGAGGGATTCAGCGGCGAATTTAAGTTCGAGATGAGTAACCACC
CGATATGCGGCGTTGGAACCTATATATATGTCGAGAAAAAAAGCAACGAGATAAAGCTGATCCCTATCACTAGTTTCGTG
GATGTGGAGGGTTTACTCGAATACCTAAGAGAGAAATGGGAGGACCTCGTAACTGGGTCGAACAGGTATATGGTTGGGCT
GAGGCTGTTATATTCCATAAGGAAATTCATTGACTCAAGCAAGCAGCCCGAGGAATTCGACTTATACAAGCTATTGTTCA
ACGTTATAATAAAGCGAAGCTATGAGGCACTGGGTGAGCTCCATTACAAGCTATTATTCCTGGGCCAAATGCACTTCATG
GACCTCTACAACTACGATATACAGAGGGTACAGAGATGCAATATACATTACTCGGTGCCAGATGGTAGATTAATACCTTT
CTGCGCATTCAACATATTCGACGACATATACAGGGATAAAATACATAAAGAATACGGTATATCACTTGAAGAATACTCGA
GCAAATACGGTCTACCAAAAGGACAGGTAACCAGGAAATATATTAGGGATAGGAGGAGGCTGGAGTCCAGTGAAATATAT
AAGCTAGCATATGAAGGAGTAATCCGCTCCAAGGCATGA

Upstream 100 bases:

>100_bases
TCTTACCCATTTAAACACCCCTGGTTTATTAGCGAAGTTGCCCTTATTATAACACGAACCTGGAGCCAGCCAAGTTTTTA
AATAGGGATCCCGTTATAAC

Downstream 100 bases:

>100_bases
TAAATGAGTCAGCAAAAAATTATTTTAGATGAATCAGATGCATGAATCAATTATATTTTTCCAGACCTTAGGAAATCCCT
TATAAGCCCTATACCCACTG

Product: putative Fe-S oxidoreductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 572; Mature: 572

Protein sequence:

>572_residues
MFIDYLVGDLSIQESSKKPGEIVYILPKLHSGEEVLSLTTSVCPYCYRVLPAVIVERDGKVYIRRICPEHGEIEELYYGD
VDFYKRVVKYTEDGRGARHIYTQVKTLCPFNCGLCPMHKQHTALVNMVVTNRCNLSCWYCFFYSEASGYVYEPRLDQIRE
MVRSIKKQGVTVAIQLTGGEPLLREDLVDIVKLLKEEGVRHIQLNTNGIRFAELYIEDPVKAVEYARELRSSGVNTVYLS
FDGVTPVTNWKNHWEVPYILETFRKAGMTSTVLVPTVIKGVNTHELGAIVRFAAKHMDVIRAVNFQPVSLTGYMKKHERE
KYRITIPEVVKLIEEQTDGQVTRDAWFPINVSALFSRFIEGFSGEFKFEMSNHPICGVGTYIYVEKKSNEIKLIPITSFV
DVEGLLEYLREKWEDLVTGSNRYMVGLRLLYSIRKFIDSSKQPEEFDLYKLLFNVIIKRSYEALGELHYKLLFLGQMHFM
DLYNYDIQRVQRCNIHYSVPDGRLIPFCAFNIFDDIYRDKIHKEYGISLEEYSSKYGLPKGQVTRKYIRDRRRLESSEIY
KLAYEGVIRSKA

Sequences:

>Translated_572_residues
MFIDYLVGDLSIQESSKKPGEIVYILPKLHSGEEVLSLTTSVCPYCYRVLPAVIVERDGKVYIRRICPEHGEIEELYYGD
VDFYKRVVKYTEDGRGARHIYTQVKTLCPFNCGLCPMHKQHTALVNMVVTNRCNLSCWYCFFYSEASGYVYEPRLDQIRE
MVRSIKKQGVTVAIQLTGGEPLLREDLVDIVKLLKEEGVRHIQLNTNGIRFAELYIEDPVKAVEYARELRSSGVNTVYLS
FDGVTPVTNWKNHWEVPYILETFRKAGMTSTVLVPTVIKGVNTHELGAIVRFAAKHMDVIRAVNFQPVSLTGYMKKHERE
KYRITIPEVVKLIEEQTDGQVTRDAWFPINVSALFSRFIEGFSGEFKFEMSNHPICGVGTYIYVEKKSNEIKLIPITSFV
DVEGLLEYLREKWEDLVTGSNRYMVGLRLLYSIRKFIDSSKQPEEFDLYKLLFNVIIKRSYEALGELHYKLLFLGQMHFM
DLYNYDIQRVQRCNIHYSVPDGRLIPFCAFNIFDDIYRDKIHKEYGISLEEYSSKYGLPKGQVTRKYIRDRRRLESSEIY
KLAYEGVIRSKA
>Mature_572_residues
MFIDYLVGDLSIQESSKKPGEIVYILPKLHSGEEVLSLTTSVCPYCYRVLPAVIVERDGKVYIRRICPEHGEIEELYYGD
VDFYKRVVKYTEDGRGARHIYTQVKTLCPFNCGLCPMHKQHTALVNMVVTNRCNLSCWYCFFYSEASGYVYEPRLDQIRE
MVRSIKKQGVTVAIQLTGGEPLLREDLVDIVKLLKEEGVRHIQLNTNGIRFAELYIEDPVKAVEYARELRSSGVNTVYLS
FDGVTPVTNWKNHWEVPYILETFRKAGMTSTVLVPTVIKGVNTHELGAIVRFAAKHMDVIRAVNFQPVSLTGYMKKHERE
KYRITIPEVVKLIEEQTDGQVTRDAWFPINVSALFSRFIEGFSGEFKFEMSNHPICGVGTYIYVEKKSNEIKLIPITSFV
DVEGLLEYLREKWEDLVTGSNRYMVGLRLLYSIRKFIDSSKQPEEFDLYKLLFNVIIKRSYEALGELHYKLLFLGQMHFM
DLYNYDIQRVQRCNIHYSVPDGRLIPFCAFNIFDDIYRDKIHKEYGISLEEYSSKYGLPKGQVTRKYIRDRRRLESSEIY
KLAYEGVIRSKA

Specific function: Together With Moac, Is Involved In The Conversion Of A Guanosine Derivative (Gxp) Into Molybdopterin Precursor Z. [C]

COG id: COG1964

COG function: function code R; Predicted Fe-S oxidoreductases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI116734668, Length=308, Percent_Identity=26.9480519480519, Blast_Score=74, Evalue=6e-13,
Organism=Homo sapiens, GI22027536, Length=307, Percent_Identity=26.3843648208469, Blast_Score=73, Evalue=7e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006638
- InterPro:   IPR007197 [H]

Pfam domain/function: PF04055 Radical_SAM [H]

EC number: NA

Molecular weight: Translated: 66487; Mature: 66487

Theoretical pI: Translated: 8.00; Mature: 8.00

Prosite motif: PS01305 MOAA_NIFB_PQQE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFIDYLVGDLSIQESSKKPGEIVYILPKLHSGEEVLSLTTSVCPYCYRVLPAVIVERDGK
CCHHEEECCCEEECCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCC
VYIRRICPEHGEIEELYYGDVDFYKRVVKYTEDGRGARHIYTQVKTLCPFNCGLCPMHKQ
EEEEECCCCCCCCHHEEECCHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCCCCCCHH
HTALVNMVVTNRCNLSCWYCFFYSEASGYVYEPRLDQIREMVRSIKKQGVTVAIQLTGGE
HHHHHHHHHHCCCCCEEEEEEEEECCCCEEECCHHHHHHHHHHHHHHCCCEEEEEECCCC
PLLREDLVDIVKLLKEEGVRHIQLNTNGIRFAELYIEDPVKAVEYARELRSSGVNTVYLS
CHHHHHHHHHHHHHHHCCCEEEEEECCCEEEEEEEECCHHHHHHHHHHHHHCCCCEEEEE
FDGVTPVTNWKNHWEVPYILETFRKAGMTSTVLVPTVIKGVNTHELGAIVRFAAKHMDVI
ECCCCCCCCCCCCCCCHHHHHHHHHCCCCCEEHHHHHHCCCCCHHHHHHHHHHHHHHHHH
RAVNFQPVSLTGYMKKHEREKYRITIPEVVKLIEEQTDGQVTRDAWFPINVSALFSRFIE
HHCCCCEEEHHHHHHHHCCCCEEEEHHHHHHHHHHCCCCCEEECCCCCEEHHHHHHHHHH
GFSGEFKFEMSNHPICGVGTYIYVEKKSNEIKLIPITSFVDVEGLLEYLREKWEDLVTGS
CCCCEEEEEECCCCEEEECEEEEEEECCCCEEEEEECCHHCHHHHHHHHHHHHHHHHCCC
NRYMVGLRLLYSIRKFIDSSKQPEEFDLYKLLFNVIIKRSYEALGELHYKLLFLGQMHFM
CCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DLYNYDIQRVQRCNIHYSVPDGRLIPFCAFNIFDDIYRDKIHKEYGISLEEYSSKYGLPK
HHHHHHHHHHHHCCEEEECCCCCEEHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCC
GQVTRKYIRDRRRLESSEIYKLAYEGVIRSKA
HHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MFIDYLVGDLSIQESSKKPGEIVYILPKLHSGEEVLSLTTSVCPYCYRVLPAVIVERDGK
CCHHEEECCCEEECCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCC
VYIRRICPEHGEIEELYYGDVDFYKRVVKYTEDGRGARHIYTQVKTLCPFNCGLCPMHKQ
EEEEECCCCCCCCHHEEECCHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCCCCCCHH
HTALVNMVVTNRCNLSCWYCFFYSEASGYVYEPRLDQIREMVRSIKKQGVTVAIQLTGGE
HHHHHHHHHHCCCCCEEEEEEEEECCCCEEECCHHHHHHHHHHHHHHCCCEEEEEECCCC
PLLREDLVDIVKLLKEEGVRHIQLNTNGIRFAELYIEDPVKAVEYARELRSSGVNTVYLS
CHHHHHHHHHHHHHHHCCCEEEEEECCCEEEEEEEECCHHHHHHHHHHHHHCCCCEEEEE
FDGVTPVTNWKNHWEVPYILETFRKAGMTSTVLVPTVIKGVNTHELGAIVRFAAKHMDVI
ECCCCCCCCCCCCCCCHHHHHHHHHCCCCCEEHHHHHHCCCCCHHHHHHHHHHHHHHHHH
RAVNFQPVSLTGYMKKHEREKYRITIPEVVKLIEEQTDGQVTRDAWFPINVSALFSRFIE
HHCCCCEEEHHHHHHHHCCCCEEEEHHHHHHHHHHCCCCCEEECCCCCEEHHHHHHHHHH
GFSGEFKFEMSNHPICGVGTYIYVEKKSNEIKLIPITSFVDVEGLLEYLREKWEDLVTGS
CCCCEEEEEECCCCEEEECEEEEEEECCCCEEEEEECCHHCHHHHHHHHHHHHHHHHCCC
NRYMVGLRLLYSIRKFIDSSKQPEEFDLYKLLFNVIIKRSYEALGELHYKLLFLGQMHFM
CCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DLYNYDIQRVQRCNIHYSVPDGRLIPFCAFNIFDDIYRDKIHKEYGISLEEYSSKYGLPK
HHHHHHHHHHHHCCEEEECCCCCEEHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCC
GQVTRKYIRDRRRLESSEIYKLAYEGVIRSKA
HHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: Fe [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]