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The map label for this gene is 218884619

Identifier: 218884619

GI number: 218884619

Start: 1222138

End: 1222935

Strand: Reverse

Name: 218884619

Synonym: DKAM_1308

Alternate gene names: NA

Gene position: 1222935-1222138 (Counterclockwise)

Preceding gene: 218884621

Following gene: 218884615

Centisome position: 89.58

GC content: 42.86

Gene sequence:

>798_bases
ATGAGTGCAGGCGATATAATAAGTGAAAACGACGATGTATTAATAGTGTTTGATGAGAAAAGGAGGTTTATTGTTAAGGC
TAGGAAAGAAGGAGTCCTAGGTACAGATAAAGGGGTTGTAAGGCTCAGTGATTTGATTGGGAAACCATATGGCTCCATTG
TTAAAACCTCGAGAGGAATAGAAGTACTGATTCTTAAACCCCTTCCATTCGACTATTCCCTACTAGTTCAACGTGTAACA
CAAGTGATTTACCCGAAGGATGCCGGCTTAATGATCTACCTCTCAGGAATCAAACCCGGCTCTAAAATAGGTGAAGCCGG
AGTTGGCTCTGGAGCACTCACAGTAATGCTGGCTAGTATTATTGGGGATAGTGGGTTACTATATGGATTCGATATCTCTG
AGAAAAGCCTCGAAAACACGAAGACCAGGCTTGAGAGGGTTGACTTAATCAATAGGGTTAGATTACTTAAGCATGATATA
AGGGAACCGGTCTCACTAGGCGAGACCCTCGACTCATTCTTCCTGGATATACCAGATCCCTGGAACGCTGTAAACACCGT
TGCAGGGTTAATAAAGACAAGCGGGACGCTATTAGTCTATGTTCCAACGATTAACCAGGTTGAAAAAACAGTGTTGAAAC
TACAGGAATCCGGTTGTTTCACCGATATACATTCCTATGAAGTATTACTTAGAGAGTATAAAGTAGATAGGGATGCGGTT
AGACCCTTCACCAGGATGGTGGGTCACACAGGGTACATCATCTTCGCTAGGAGGATCAAGTGTAATTTAGGCACCTAA

Upstream 100 bases:

>100_bases
CTCTTCCCTAGATTTATAAGGATACATGAATCTTTTATAGGATCGATGCTGAAGGTTGGTATTTCTGATTAGTGATGAAT
GACGCCAGGACTGAGCAGTA

Downstream 100 bases:

>100_bases
TACTAGGAAACCGTTTCCCGCCCCAGGTTTTCTGGGTCTTCGTGGGGTGGTTTATCATGGTTCCTCCCCCGGCTCCCTCC
CCATAGTCATCCATGGGTCT

Product: type 11 methyltransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 265; Mature: 264

Protein sequence:

>265_residues
MSAGDIISENDDVLIVFDEKRRFIVKARKEGVLGTDKGVVRLSDLIGKPYGSIVKTSRGIEVLILKPLPFDYSLLVQRVT
QVIYPKDAGLMIYLSGIKPGSKIGEAGVGSGALTVMLASIIGDSGLLYGFDISEKSLENTKTRLERVDLINRVRLLKHDI
REPVSLGETLDSFFLDIPDPWNAVNTVAGLIKTSGTLLVYVPTINQVEKTVLKLQESGCFTDIHSYEVLLREYKVDRDAV
RPFTRMVGHTGYIIFARRIKCNLGT

Sequences:

>Translated_265_residues
MSAGDIISENDDVLIVFDEKRRFIVKARKEGVLGTDKGVVRLSDLIGKPYGSIVKTSRGIEVLILKPLPFDYSLLVQRVT
QVIYPKDAGLMIYLSGIKPGSKIGEAGVGSGALTVMLASIIGDSGLLYGFDISEKSLENTKTRLERVDLINRVRLLKHDI
REPVSLGETLDSFFLDIPDPWNAVNTVAGLIKTSGTLLVYVPTINQVEKTVLKLQESGCFTDIHSYEVLLREYKVDRDAV
RPFTRMVGHTGYIIFARRIKCNLGT
>Mature_264_residues
SAGDIISENDDVLIVFDEKRRFIVKARKEGVLGTDKGVVRLSDLIGKPYGSIVKTSRGIEVLILKPLPFDYSLLVQRVTQ
VIYPKDAGLMIYLSGIKPGSKIGEAGVGSGALTVMLASIIGDSGLLYGFDISEKSLENTKTRLERVDLINRVRLLKHDIR
EPVSLGETLDSFFLDIPDPWNAVNTVAGLIKTSGTLLVYVPTINQVEKTVLKLQESGCFTDIHSYEVLLREYKVDRDAVR
PFTRMVGHTGYIIFARRIKCNLGT

Specific function: Unknown

COG id: COG2519

COG function: function code J; tRNA(1-methyladenosine) methyltransferase and related methyltransferases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily. TRM61 family [H]

Homologues:

Organism=Homo sapiens, GI123173772, Length=280, Percent_Identity=28.5714285714286, Blast_Score=123, Evalue=2e-28,
Organism=Homo sapiens, GI222831587, Length=194, Percent_Identity=28.3505154639175, Blast_Score=77, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17509459, Length=241, Percent_Identity=28.6307053941909, Blast_Score=92, Evalue=4e-19,
Organism=Saccharomyces cerevisiae, GI6322336, Length=263, Percent_Identity=28.8973384030418, Blast_Score=92, Evalue=8e-20,
Organism=Drosophila melanogaster, GI24650257, Length=206, Percent_Identity=29.126213592233, Blast_Score=89, Evalue=4e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014816 [H]

Pfam domain/function: PF08704 GCD14 [H]

EC number: =2.1.1.36 [H]

Molecular weight: Translated: 29331; Mature: 29199

Theoretical pI: Translated: 8.95; Mature: 8.95

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSAGDIISENDDVLIVFDEKRRFIVKARKEGVLGTDKGVVRLSDLIGKPYGSIVKTSRGI
CCCCCCCCCCCCEEEEECCCCEEEEHHHHCCCCCCCCCHHHHHHHHCCCCHHHHHCCCCC
EVLILKPLPFDYSLLVQRVTQVIYPKDAGLMIYLSGIKPGSKIGEAGVGSGALTVMLASI
EEEEECCCCCCHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCCCCCCCHHHHHHHHHH
IGDSGLLYGFDISEKSLENTKTRLERVDLINRVRLLKHDIREPVSLGETLDSFFLDIPDP
HCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCC
WNAVNTVAGLIKTSGTLLVYVPTINQVEKTVLKLQESGCFTDIHSYEVLLREYKVDRDAV
CHHHHHHHHHHHCCCEEEEEECCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCHHHH
RPFTRMVGHTGYIIFARRIKCNLGT
HHHHHHHCCCCEEEEEEEEEECCCC
>Mature Secondary Structure 
SAGDIISENDDVLIVFDEKRRFIVKARKEGVLGTDKGVVRLSDLIGKPYGSIVKTSRGI
CCCCCCCCCCCEEEEECCCCEEEEHHHHCCCCCCCCCHHHHHHHHCCCCHHHHHCCCCC
EVLILKPLPFDYSLLVQRVTQVIYPKDAGLMIYLSGIKPGSKIGEAGVGSGALTVMLASI
EEEEECCCCCCHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCCCCCCCHHHHHHHHHH
IGDSGLLYGFDISEKSLENTKTRLERVDLINRVRLLKHDIREPVSLGETLDSFFLDIPDP
HCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCC
WNAVNTVAGLIKTSGTLLVYVPTINQVEKTVLKLQESGCFTDIHSYEVLLREYKVDRDAV
CHHHHHHHHHHHCCCEEEEEECCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCHHHH
RPFTRMVGHTGYIIFARRIKCNLGT
HHHHHHHCCCCEEEEEEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]