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The map label for this gene is 218884598

Identifier: 218884598

GI number: 218884598

Start: 1204267

End: 1206210

Strand: Reverse

Name: 218884598

Synonym: DKAM_1287

Alternate gene names: NA

Gene position: 1206210-1204267 (Counterclockwise)

Preceding gene: 218884599

Following gene: 218884597

Centisome position: 88.35

GC content: 45.47

Gene sequence:

>1944_bases
GTGAAGCCAGATAGAATACTGCTAGAGAAGAACAAATTAGAGCTGTTGAAGAACATAATGGAAGAGATACCTCCAGAGCT
TGAGTTATCTAACATAGAGTTCGAGGGCCCCTTCATAGTAATATATGTAAGGAACAGGGAGGCCATCGAGAAATACCTTG
ATCTAGCACAGAATATAGCTAAGAAAGTACGTAAGAGAGTCGTCATCAGGGTTTCCCCTGAGAACCGACTTCCGCCAGAG
GAGGCAAAGGAACTAATAAAGCTACTGGCACCTAAAGACGCCGGGATAGATCCCAATGGGATATACTTCGATGAAGCCTT
AGGCGAGGTATGGGTTAAAGTAGAAAAGCCTGGCTACCTGGTTGGAAGAGGAAGCATGATGAGGCACTTGATCCTGGCTA
AAACAGGGTGGCGTGTTATCCCTCAGCGTTCATCACCACTGGAATCGAAGACCCTCTACGAGGTACTCAATAATGTATTG
AAGCAGAGTGGCTATAGAGTCGAGTATCTGAGGCGACTCGGAGAGAGGATACATAGGGATGTAATATATAGGAACAACTA
TGTCAAAGTAACAGGGCTAGGTGGCTTCAGAGAGGTTGGTAGATCGGCTATATTAGTTGAGACAAGGGAGAGTAAGATAC
TGCTGGATCTCGGGTTAAACACTGGCACTATAGACGACCCCAATAAGGCTTACCCATTCCTAGAAATAGACTCCCTGAGA
CTCGAGGAGCTGGATGGTGTCGTAGTGACCCATGCCCATCTAGACCACGTAGGGTTAGTTCCCATACTCTACAAGTATGG
TTACCGTGGACCCGTGTATGTGACGAAGCCTACGAGGGAGTTAATGATCGTTATGTTAAAGGACTTGATTGATGTAACCA
GAAGGTCTGGTAGGTACATACCATTCTCAGAGAGGGACATATCTACAATGCTACTTCACACTATAACCGTGGACTATGAT
GAAGTAACGGATGTAGCACCGGATATAAAGCTCACAATGTATAATGCTGGCCATATCCTTGGCTCTGCAATAGTCCACTT
GCACATAGGCATGGGCCTCCATAATATAGTCTATACAGGGGATTTCAAGTACTCTGAGACAAGACTACTCAATAAAGCCA
ATACAGTGTTCCCACGGGTTGAAACCCTCATAATGGAGGGCACTTATGGAGCAACCCTCCAGGAGAGTAGGATTCAAGCC
GAGCAACAATTAATCGATATAGTGAAGAGGACGAGCGAGAGAAACGGAGTAGTGTTAATACCGGTATTCGCTGTTGGAAG
AGGACAAGAAATAATACTCATACTTAATGAGGCCATGAAGAACGGTAGAATACCAAGGATGAATATATATGTCGAGGGAT
TAGTTAACGAGGTAACAGCTATACACACACAGTACCCTGAGTACCTGAATAAATCCCTTAGAGAAGCAATATACAATGGA
GAAAACCCGTTTACATCAGAATGGTTAAAACCCATAGAAACCGGGGTGGCGAGGCCGGACATCATTGAAGACAAGCCATC
CATAATAATAGCGACAAGTGGCATGCTCACCGGTGGCCCTGCAGTAGACTACCTGAGGCTGTTGGCCAGCGATGAGAGAA
ACTCCCTGGTGTTCGTAGGATATCAGGCTGAGGGGACGCTTGGTAGGAAAATAAAAGACGGCGCTAGAGAGATAACCATG
GTTGTTGAAAACAAGGTTGAGGCAATACCTATAAAGCTAGAGGTATATAGTATTGAGGGCTTTAGTGGACATAGTGATCA
ACGCGAGCTATTAGAGTATGCTAGAGACGTCTCGCCCAGGCCAAGGAAGATACTACTGAACCATGGAGAACCCACAGCAC
TCAGCACGCTGGCTACACTACTTAGGAGTGATAAGGAATTAAAGTCTAAGGGGCGCCCCGAGGTGCTAGTGCCTAATATA
TTGGACACCATTAATTTAACATAG

Upstream 100 bases:

>100_bases
TATAGACCGCGTTAAAGTTAAAAACCCTCATATATGTTTCATTAATCAGCACTACGATAGTGTTTACTCCTCAGGAAATA
CAGGAGTGGTGTGATGACTT

Downstream 100 bases:

>100_bases
CATTAAAATCTATCACAGATTAGTGGAGTTCAGGTGACTCTATGAATAGGGTTTTATTCCCGGGTAGATTCCAGCCATTC
CACAATGGGCATTTATCCGT

Product: mRNA 3'-end polyadenylation factor

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 647; Mature: 647

Protein sequence:

>647_residues
MKPDRILLEKNKLELLKNIMEEIPPELELSNIEFEGPFIVIYVRNREAIEKYLDLAQNIAKKVRKRVVIRVSPENRLPPE
EAKELIKLLAPKDAGIDPNGIYFDEALGEVWVKVEKPGYLVGRGSMMRHLILAKTGWRVIPQRSSPLESKTLYEVLNNVL
KQSGYRVEYLRRLGERIHRDVIYRNNYVKVTGLGGFREVGRSAILVETRESKILLDLGLNTGTIDDPNKAYPFLEIDSLR
LEELDGVVVTHAHLDHVGLVPILYKYGYRGPVYVTKPTRELMIVMLKDLIDVTRRSGRYIPFSERDISTMLLHTITVDYD
EVTDVAPDIKLTMYNAGHILGSAIVHLHIGMGLHNIVYTGDFKYSETRLLNKANTVFPRVETLIMEGTYGATLQESRIQA
EQQLIDIVKRTSERNGVVLIPVFAVGRGQEIILILNEAMKNGRIPRMNIYVEGLVNEVTAIHTQYPEYLNKSLREAIYNG
ENPFTSEWLKPIETGVARPDIIEDKPSIIIATSGMLTGGPAVDYLRLLASDERNSLVFVGYQAEGTLGRKIKDGAREITM
VVENKVEAIPIKLEVYSIEGFSGHSDQRELLEYARDVSPRPRKILLNHGEPTALSTLATLLRSDKELKSKGRPEVLVPNI
LDTINLT

Sequences:

>Translated_647_residues
MKPDRILLEKNKLELLKNIMEEIPPELELSNIEFEGPFIVIYVRNREAIEKYLDLAQNIAKKVRKRVVIRVSPENRLPPE
EAKELIKLLAPKDAGIDPNGIYFDEALGEVWVKVEKPGYLVGRGSMMRHLILAKTGWRVIPQRSSPLESKTLYEVLNNVL
KQSGYRVEYLRRLGERIHRDVIYRNNYVKVTGLGGFREVGRSAILVETRESKILLDLGLNTGTIDDPNKAYPFLEIDSLR
LEELDGVVVTHAHLDHVGLVPILYKYGYRGPVYVTKPTRELMIVMLKDLIDVTRRSGRYIPFSERDISTMLLHTITVDYD
EVTDVAPDIKLTMYNAGHILGSAIVHLHIGMGLHNIVYTGDFKYSETRLLNKANTVFPRVETLIMEGTYGATLQESRIQA
EQQLIDIVKRTSERNGVVLIPVFAVGRGQEIILILNEAMKNGRIPRMNIYVEGLVNEVTAIHTQYPEYLNKSLREAIYNG
ENPFTSEWLKPIETGVARPDIIEDKPSIIIATSGMLTGGPAVDYLRLLASDERNSLVFVGYQAEGTLGRKIKDGAREITM
VVENKVEAIPIKLEVYSIEGFSGHSDQRELLEYARDVSPRPRKILLNHGEPTALSTLATLLRSDKELKSKGRPEVLVPNI
LDTINLT
>Mature_647_residues
MKPDRILLEKNKLELLKNIMEEIPPELELSNIEFEGPFIVIYVRNREAIEKYLDLAQNIAKKVRKRVVIRVSPENRLPPE
EAKELIKLLAPKDAGIDPNGIYFDEALGEVWVKVEKPGYLVGRGSMMRHLILAKTGWRVIPQRSSPLESKTLYEVLNNVL
KQSGYRVEYLRRLGERIHRDVIYRNNYVKVTGLGGFREVGRSAILVETRESKILLDLGLNTGTIDDPNKAYPFLEIDSLR
LEELDGVVVTHAHLDHVGLVPILYKYGYRGPVYVTKPTRELMIVMLKDLIDVTRRSGRYIPFSERDISTMLLHTITVDYD
EVTDVAPDIKLTMYNAGHILGSAIVHLHIGMGLHNIVYTGDFKYSETRLLNKANTVFPRVETLIMEGTYGATLQESRIQA
EQQLIDIVKRTSERNGVVLIPVFAVGRGQEIILILNEAMKNGRIPRMNIYVEGLVNEVTAIHTQYPEYLNKSLREAIYNG
ENPFTSEWLKPIETGVARPDIIEDKPSIIIATSGMLTGGPAVDYLRLLASDERNSLVFVGYQAEGTLGRKIKDGAREITM
VVENKVEAIPIKLEVYSIEGFSGHSDQRELLEYARDVSPRPRKILLNHGEPTALSTLATLLRSDKELKSKGRPEVLVPNI
LDTINLT

Specific function: Unknown

COG id: COG1782

COG function: function code R; Predicted metal-dependent RNase, consists of a metallo-beta-lactamase domain and an RNA-binding KH domain

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI7706427, Length=459, Percent_Identity=32.0261437908497, Blast_Score=218, Evalue=1e-56,
Organism=Homo sapiens, GI33300633, Length=440, Percent_Identity=30, Blast_Score=205, Evalue=1e-52,
Organism=Homo sapiens, GI34101288, Length=391, Percent_Identity=23.5294117647059, Blast_Score=89, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI32564696, Length=439, Percent_Identity=28.7015945330296, Blast_Score=196, Evalue=4e-50,
Organism=Caenorhabditis elegans, GI32566029, Length=438, Percent_Identity=29.6803652968037, Blast_Score=182, Evalue=7e-46,
Organism=Caenorhabditis elegans, GI17559452, Length=427, Percent_Identity=23.1850117096019, Blast_Score=85, Evalue=1e-16,
Organism=Saccharomyces cerevisiae, GI6323307, Length=456, Percent_Identity=30.0438596491228, Blast_Score=187, Evalue=3e-48,
Organism=Drosophila melanogaster, GI24648013, Length=446, Percent_Identity=31.1659192825112, Blast_Score=207, Evalue=1e-53,
Organism=Drosophila melanogaster, GI21358523, Length=456, Percent_Identity=29.3859649122807, Blast_Score=201, Evalue=1e-51,
Organism=Drosophila melanogaster, GI21358013, Length=404, Percent_Identity=25, Blast_Score=103, Evalue=3e-22,
Organism=Drosophila melanogaster, GI24650920, Length=294, Percent_Identity=25.5102040816327, Blast_Score=78, Evalue=2e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022712
- InterPro:   IPR001279
- InterPro:   IPR004087
- InterPro:   IPR019975
- InterPro:   IPR004044
- InterPro:   IPR011108 [H]

Pfam domain/function: PF10996 Beta-Casp; PF07650 KH_2; PF00753 Lactamase_B; PF07521 RMMBL [H]

EC number: NA

Molecular weight: Translated: 73202; Mature: 73202

Theoretical pI: Translated: 7.03; Mature: 7.03

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKPDRILLEKNKLELLKNIMEEIPPELELSNIEFEGPFIVIYVRNREAIEKYLDLAQNIA
CCCCCEEEECHHHHHHHHHHHHCCCCCEECCEEECCCEEEEEECCHHHHHHHHHHHHHHH
KKVRKRVVIRVSPENRLPPEEAKELIKLLAPKDAGIDPNGIYFDEALGEVWVKVEKPGYL
HHHHHCEEEEECCCCCCCHHHHHHHHHHHCCCCCCCCCCCEEHHHHHCCEEEEECCCCEE
VGRGSMMRHLILAKTGWRVIPQRSSPLESKTLYEVLNNVLKQSGYRVEYLRRLGERIHRD
EECHHHHHHHHHHCCCCEEECCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHH
VIYRNNYVKVTGLGGFREVGRSAILVETRESKILLDLGLNTGTIDDPNKAYPFLEIDSLR
HEEECCEEEEEECCCHHHHCCCEEEEEECCCEEEEEECCCCCCCCCCCCCCCEEEECCCH
LEELDGVVVTHAHLDHVGLVPILYKYGYRGPVYVTKPTRELMIVMLKDLIDVTRRSGRYI
HHHCCCEEEEEECCCCCCHHHHHHHCCCCCCEEEECCHHHHHHHHHHHHHHHHHHCCCCC
PFSERDISTMLLHTITVDYDEVTDVAPDIKLTMYNAGHILGSAIVHLHIGMGLHNIVYTG
CCCCCCHHHEEEHHEECCHHHHHCCCCCEEEEEEECCHHHHHHHHHEEECCCCCCEEEEC
DFKYSETRLLNKANTVFPRVETLIMEGTYGATLQESRIQAEQQLIDIVKRTSERNGVVLI
CCCCCHHHHHHHHHHHHHCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHCCCCCCEEEE
PVFAVGRGQEIILILNEAMKNGRIPRMNIYVEGLVNEVTAIHTQYPEYLNKSLREAIYNG
EEEECCCCCEEEEEEEHHHHCCCCCEEEEEHHHHHHHHHHHHHHCHHHHHHHHHHHHHCC
ENPFTSEWLKPIETGVARPDIIEDKPSIIIATSGMLTGGPAVDYLRLLASDERNSLVFVG
CCCCHHHHHHHHHHCCCCCCCCCCCCCEEEEECCCCCCCHHHHHHHHHHCCCCCCEEEEE
YQAEGTLGRKIKDGAREITMVVENKVEAIPIKLEVYSIEGFSGHSDQRELLEYARDVSPR
EECCCCCCCHHHHCHHHEEHEEECCCEEEEEEEEEEEECCCCCCCCHHHHHHHHHCCCCC
PRKILLNHGEPTALSTLATLLRSDKELKSKGRPEVLVPNILDTINLT
CCEEEEECCCCHHHHHHHHHHHCCHHHHHCCCCCEECCCHHHHCCCC
>Mature Secondary Structure
MKPDRILLEKNKLELLKNIMEEIPPELELSNIEFEGPFIVIYVRNREAIEKYLDLAQNIA
CCCCCEEEECHHHHHHHHHHHHCCCCCEECCEEECCCEEEEEECCHHHHHHHHHHHHHHH
KKVRKRVVIRVSPENRLPPEEAKELIKLLAPKDAGIDPNGIYFDEALGEVWVKVEKPGYL
HHHHHCEEEEECCCCCCCHHHHHHHHHHHCCCCCCCCCCCEEHHHHHCCEEEEECCCCEE
VGRGSMMRHLILAKTGWRVIPQRSSPLESKTLYEVLNNVLKQSGYRVEYLRRLGERIHRD
EECHHHHHHHHHHCCCCEEECCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHH
VIYRNNYVKVTGLGGFREVGRSAILVETRESKILLDLGLNTGTIDDPNKAYPFLEIDSLR
HEEECCEEEEEECCCHHHHCCCEEEEEECCCEEEEEECCCCCCCCCCCCCCCEEEECCCH
LEELDGVVVTHAHLDHVGLVPILYKYGYRGPVYVTKPTRELMIVMLKDLIDVTRRSGRYI
HHHCCCEEEEEECCCCCCHHHHHHHCCCCCCEEEECCHHHHHHHHHHHHHHHHHHCCCCC
PFSERDISTMLLHTITVDYDEVTDVAPDIKLTMYNAGHILGSAIVHLHIGMGLHNIVYTG
CCCCCCHHHEEEHHEECCHHHHHCCCCCEEEEEEECCHHHHHHHHHEEECCCCCCEEEEC
DFKYSETRLLNKANTVFPRVETLIMEGTYGATLQESRIQAEQQLIDIVKRTSERNGVVLI
CCCCCHHHHHHHHHHHHHCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHCCCCCCEEEE
PVFAVGRGQEIILILNEAMKNGRIPRMNIYVEGLVNEVTAIHTQYPEYLNKSLREAIYNG
EEEECCCCCEEEEEEEHHHHCCCCCEEEEEHHHHHHHHHHHHHHCHHHHHHHHHHHHHCC
ENPFTSEWLKPIETGVARPDIIEDKPSIIIATSGMLTGGPAVDYLRLLASDERNSLVFVG
CCCCHHHHHHHHHHCCCCCCCCCCCCCEEEEECCCCCCCHHHHHHHHHHCCCCCCEEEEE
YQAEGTLGRKIKDGAREITMVVENKVEAIPIKLEVYSIEGFSGHSDQRELLEYARDVSPR
EECCCCCCCHHHHCHHHEEHEEECCCEEEEEEEEEEEECCCCCCCCHHHHHHHHHCCCCC
PRKILLNHGEPTALSTLATLLRSDKELKSKGRPEVLVPNILDTINLT
CCEEEEECCCCHHHHHHHHHHHCCHHHHHCCCCCEECCCHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]