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The map label for this gene is dcm [C]

Identifier: 218884576

GI number: 218884576

Start: 1183703

End: 1184677

Strand: Reverse

Name: dcm [C]

Synonym: DKAM_1265

Alternate gene names: 218884576

Gene position: 1184677-1183703 (Counterclockwise)

Preceding gene: 218884577

Following gene: 218884575

Centisome position: 86.78

GC content: 44.92

Gene sequence:

>975_bases
GTGAAGACTGTTTATAAATACATAGATGTATTCTCTGGTGCAGGGGGCTTCTCACTAGGATTCCATCTCACAGGTAGATT
CAAATCCCTGCTAGCCATTGACAATTTCAAACCAGCTGCCCTAACCTATAAAACCAATTTCCCCCATGCACTAGTGGTTA
ACGAGGATGTCAAGGAGTTAGACAAGGAGTTATTAACGGGTATAGTGAAACCCGATGAAATTGATGTAATCATAGGTAGC
CCGCCCTGTGAGCCATTCACAGGTGCTAATCCTATGAGGAAAAAGGATCCATTAGACCGCTTATACAGTGATCCTATGGG
CCAGCTAACATTACACTTTATAAGGATCGTCGGGTATTATCGCCCGAAAATATTCGTAATGGAGAATGTACCAGCAATAA
CTGAGGATGGATTACGTGATGCATTATCAATAGAGTTCAAGCGCGTAGGCTATGAGAAGATATACTTTAACGCCTTGCTA
GCCGAGGACTATGAAACACCTAGCCACAGAAAAAGAGTATTCATATCGAATATTCCCATAACACCGAGGAAATCCTCGAG
AAGGATAACCGTTAAGGAGGCATTGAGCAATCTACCAGAGCCAGGTGAAGCGTTCCCAAATCATGAGAGGCCCCCAGACC
CCCCATGGAGGAAGCTTAAGAGAATCCACCGGTTGAGATGGGGAGATGCGTTAATCCACTACCATGGTGCAGAAAAACCC
CTTCCAAACATGGTTAAGTTGAATCCAAATACTATAGCTCCAACAGTCCTTGGATCATCAAGGTTTATACATCCATTCGA
GGACAGATTTCTCACGGTTAGAGAGCAAGCCAGGCTGATGGGTTTCACCGACACATTTGTTTTTATAGGTGGAAGGGATG
AACAGTATAACATGGTGGGAGAAGCTGTACCGGCTCCCCTTGCAAAAGCTATAGCATGGTATCTCGCCGGGAAGCTGGAT
GAGGAGGTGACGTAA

Upstream 100 bases:

>100_bases
AGGTATTGGTTGAAGCCGATAAGTCTAAGACGGTGGAAGTCTTAAAGGAGTTGATTAGTAAAGTAGATAATTTAATTAAG
AGGGTTGAACGGGTTTAGAA

Downstream 100 bases:

>100_bases
ATGTATATAGCCTTATATTCACCGTCAAGTATTCAGAAGCTCGTTGACTTCATAAAGACAGTGTACGCTATAAAGGGGCT
AGTACCAGTGGTGATCAAGC

Product: Cytosine-specific DNA methylase

Products: NA

Alternate protein names: Cytosine-specific methyltransferase MJ0563; M.MjaVIIIP [H]

Number of amino acids: Translated: 324; Mature: 324

Protein sequence:

>324_residues
MKTVYKYIDVFSGAGGFSLGFHLTGRFKSLLAIDNFKPAALTYKTNFPHALVVNEDVKELDKELLTGIVKPDEIDVIIGS
PPCEPFTGANPMRKKDPLDRLYSDPMGQLTLHFIRIVGYYRPKIFVMENVPAITEDGLRDALSIEFKRVGYEKIYFNALL
AEDYETPSHRKRVFISNIPITPRKSSRRITVKEALSNLPEPGEAFPNHERPPDPPWRKLKRIHRLRWGDALIHYHGAEKP
LPNMVKLNPNTIAPTVLGSSRFIHPFEDRFLTVREQARLMGFTDTFVFIGGRDEQYNMVGEAVPAPLAKAIAWYLAGKLD
EEVT

Sequences:

>Translated_324_residues
MKTVYKYIDVFSGAGGFSLGFHLTGRFKSLLAIDNFKPAALTYKTNFPHALVVNEDVKELDKELLTGIVKPDEIDVIIGS
PPCEPFTGANPMRKKDPLDRLYSDPMGQLTLHFIRIVGYYRPKIFVMENVPAITEDGLRDALSIEFKRVGYEKIYFNALL
AEDYETPSHRKRVFISNIPITPRKSSRRITVKEALSNLPEPGEAFPNHERPPDPPWRKLKRIHRLRWGDALIHYHGAEKP
LPNMVKLNPNTIAPTVLGSSRFIHPFEDRFLTVREQARLMGFTDTFVFIGGRDEQYNMVGEAVPAPLAKAIAWYLAGKLD
EEVT
>Mature_324_residues
MKTVYKYIDVFSGAGGFSLGFHLTGRFKSLLAIDNFKPAALTYKTNFPHALVVNEDVKELDKELLTGIVKPDEIDVIIGS
PPCEPFTGANPMRKKDPLDRLYSDPMGQLTLHFIRIVGYYRPKIFVMENVPAITEDGLRDALSIEFKRVGYEKIYFNALL
AEDYETPSHRKRVFISNIPITPRKSSRRITVKEALSNLPEPGEAFPNHERPPDPPWRKLKRIHRLRWGDALIHYHGAEKP
LPNMVKLNPNTIAPTVLGSSRFIHPFEDRFLTVREQARLMGFTDTFVFIGGRDEQYNMVGEAVPAPLAKAIAWYLAGKLD
EEVT

Specific function: This Methylase Recognizes The Double-Stranded Sequence Ccwgg, Causes Specific Methylation On C-2 On Both Strands. [C]

COG id: COG0270

COG function: function code L; Site-specific DNA methylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the C5-methyltransferase family [H]

Homologues:

Organism=Homo sapiens, GI4503351, Length=243, Percent_Identity=27.9835390946502, Blast_Score=94, Evalue=2e-19,
Organism=Homo sapiens, GI195927037, Length=243, Percent_Identity=27.9835390946502, Blast_Score=94, Evalue=2e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001525 [H]

Pfam domain/function: PF00145 DNA_methylase [H]

EC number: =2.1.1.37 [H]

Molecular weight: Translated: 36822; Mature: 36822

Theoretical pI: Translated: 9.30; Mature: 9.30

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKTVYKYIDVFSGAGGFSLGFHLTGRFKSLLAIDNFKPAALTYKTNFPHALVVNEDVKEL
CCHHHHHHHHHCCCCCCEEEEEECCHHHHHHEECCCCCCEEEEECCCCEEEEECCHHHHH
DKELLTGIVKPDEIDVIIGSPPCEPFTGANPMRKKDPLDRLYSDPMGQLTLHFIRIVGYY
HHHHHHHCCCCCCEEEEECCCCCCCCCCCCCCCCCCHHHHHHCCCHHHHHHHHHHHHHHH
RPKIFVMENVPAITEDGLRDALSIEFKRVGYEKIYFNALLAEDYETPSHRKRVFISNIPI
CCEEEEEECCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCHHCEEEEECCCC
TPRKSSRRITVKEALSNLPEPGEAFPNHERPPDPPWRKLKRIHRLRWGDALIHYHGAEKP
CCCCCCCEEEHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCEEEEECCCCCC
LPNMVKLNPNTIAPTVLGSSRFIHPFEDRFLTVREQARLMGFTDTFVFIGGRDEQYNMVG
CCCEEEECCCCCCCEEECCCCCCCCHHHHHHHHHHHHHHEEEEEEEEEECCCCCCHHHHH
EAVPAPLAKAIAWYLAGKLDEEVT
HHCCHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure
MKTVYKYIDVFSGAGGFSLGFHLTGRFKSLLAIDNFKPAALTYKTNFPHALVVNEDVKEL
CCHHHHHHHHHCCCCCCEEEEEECCHHHHHHEECCCCCCEEEEECCCCEEEEECCHHHHH
DKELLTGIVKPDEIDVIIGSPPCEPFTGANPMRKKDPLDRLYSDPMGQLTLHFIRIVGYY
HHHHHHHCCCCCCEEEEECCCCCCCCCCCCCCCCCCHHHHHHCCCHHHHHHHHHHHHHHH
RPKIFVMENVPAITEDGLRDALSIEFKRVGYEKIYFNALLAEDYETPSHRKRVFISNIPI
CCEEEEEECCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCHHCEEEEECCCC
TPRKSSRRITVKEALSNLPEPGEAFPNHERPPDPPWRKLKRIHRLRWGDALIHYHGAEKP
CCCCCCCEEEHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCEEEEECCCCCC
LPNMVKLNPNTIAPTVLGSSRFIHPFEDRFLTVREQARLMGFTDTFVFIGGRDEQYNMVG
CCCEEEECCCCCCCEEECCCCCCCCHHHHHHHHHHHHHHEEEEEEEEEECCCCCCHHHHH
EAVPAPLAKAIAWYLAGKLDEEVT
HHCCHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]