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The map label for this gene is 218884455

Identifier: 218884455

GI number: 218884455

Start: 1075569

End: 1076804

Strand: Reverse

Name: 218884455

Synonym: DKAM_1144

Alternate gene names: NA

Gene position: 1076804-1075569 (Counterclockwise)

Preceding gene: 218884456

Following gene: 218884452

Centisome position: 78.87

GC content: 46.36

Gene sequence:

>1236_bases
ATGGTGTTCAATAAATATGTCTTATTAATAGTACTACTGGCTCTACTATTAATCCCACTAGTATTCTCTAACGAATCAGA
GGCGTTAATAGTCAATGGGGGCTCAAACAAGGTAAGAGTAGTGATAGGATATAGGGATGAATCCTCTAGGCAGAACCTGT
TGAGGAACCTCGGGGTATCACCAGTGAAAGAGATCAGGGATCTAAAGGTACTGGTTGTCGAGATACCTGAGTCATTGATA
ACCCGTGTTAAAAGCCTGCCGGGTATTAGATACATTGAGAAAGATATAGAGGCCAGGGCTTTCGGCATAAGCGACTATTA
TGGTGACATCAAGTGGAATATGTACATGATCGGCATAACGGATGTCTGGGACTACTATTATCAATACTATGGCAGGTATA
CATTCGGTAGGGGGGTAGTCGTAGCTGTCCTTGACACAGGTATTGATTACACCCATCCGGACCTCTATGGCAGGGTTGCA
TACTGTATAAGGACAACTGGCTCAACCACTTATAGGGGTACTTCACTAAGTAACTGCATGGATCGAAACGGGCATGGAAC
ACATGTAGCCGGGATAATTGCGGCGACTATAAATGGTGCGGGCGTAGCAGGTGTAGCACCAAACGTGACCCTGATAGCGG
TTAAAGTACTCTATGACTCAGGAAGCGGGAGCGTTACAGATATAGCTGAGGGAATAGTGGAAGCTGTGAAGGCTGGAGCA
TACATACTCAGCATGTCGCTTGGTTCCTCAAGCGATAATAGCGTGTTAAGGGATGCATCAAACTGGGCTTACCAGCAAGG
CGCTATACAGATTGTTGCAGCAGGTAACTCTGGCGATGGAAACCCAAGTACAGATAACGTTAACTACCCAGCTAGATACC
CATGGGTGATAGCTGTTGCAGCAGTGGATTCAAACGGTAATACACCATCATGGAGTAGTGATGGACCGGAGGTTGATGTG
GCGGCGCCCGGAGTCGACATATTATCTACGTACCTGAATAAAAAATACGCTTATCTAAGCGGTACATCAATGGCTACCCC
GCATGTAACAGGTGTTGTGGCAGTTATAGAAGCCATGAGGTATGCTGCTGGTAAAAGCTGGCTGGGCTTCGACGCTATTT
ATAAAGTCCTGACATCTACAGCATATGATCTAGGTTCTTCAGGCTTCGACGTTTACACCGGGTATGGACTAGTGGATGCG
TACAGCGCAGTCCAATACGCGTTAAGTCTACCCTAG

Upstream 100 bases:

>100_bases
TGCTTCTCGGTCAGTGTTATGGATCCGGCTTGTTCTCTAGATAAAAAATTTATAAAGTATCCCACTGATTACTGTATGTG
ATTTAAATCTGGGTGGGGCT

Downstream 100 bases:

>100_bases
TTTCTCCTCCAATATTTTTTCATGGGGTCTCAGACCCCCAATTCTTTTCACACTCCATGTCTCAACATGGATGTTTGATC
TCCCTGGTTCTACTCTCCTT

Product: Subtilisin-like serine protease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 411; Mature: 411

Protein sequence:

>411_residues
MVFNKYVLLIVLLALLLIPLVFSNESEALIVNGGSNKVRVVIGYRDESSRQNLLRNLGVSPVKEIRDLKVLVVEIPESLI
TRVKSLPGIRYIEKDIEARAFGISDYYGDIKWNMYMIGITDVWDYYYQYYGRYTFGRGVVVAVLDTGIDYTHPDLYGRVA
YCIRTTGSTTYRGTSLSNCMDRNGHGTHVAGIIAATINGAGVAGVAPNVTLIAVKVLYDSGSGSVTDIAEGIVEAVKAGA
YILSMSLGSSSDNSVLRDASNWAYQQGAIQIVAAGNSGDGNPSTDNVNYPARYPWVIAVAAVDSNGNTPSWSSDGPEVDV
AAPGVDILSTYLNKKYAYLSGTSMATPHVTGVVAVIEAMRYAAGKSWLGFDAIYKVLTSTAYDLGSSGFDVYTGYGLVDA
YSAVQYALSLP

Sequences:

>Translated_411_residues
MVFNKYVLLIVLLALLLIPLVFSNESEALIVNGGSNKVRVVIGYRDESSRQNLLRNLGVSPVKEIRDLKVLVVEIPESLI
TRVKSLPGIRYIEKDIEARAFGISDYYGDIKWNMYMIGITDVWDYYYQYYGRYTFGRGVVVAVLDTGIDYTHPDLYGRVA
YCIRTTGSTTYRGTSLSNCMDRNGHGTHVAGIIAATINGAGVAGVAPNVTLIAVKVLYDSGSGSVTDIAEGIVEAVKAGA
YILSMSLGSSSDNSVLRDASNWAYQQGAIQIVAAGNSGDGNPSTDNVNYPARYPWVIAVAAVDSNGNTPSWSSDGPEVDV
AAPGVDILSTYLNKKYAYLSGTSMATPHVTGVVAVIEAMRYAAGKSWLGFDAIYKVLTSTAYDLGSSGFDVYTGYGLVDA
YSAVQYALSLP
>Mature_411_residues
MVFNKYVLLIVLLALLLIPLVFSNESEALIVNGGSNKVRVVIGYRDESSRQNLLRNLGVSPVKEIRDLKVLVVEIPESLI
TRVKSLPGIRYIEKDIEARAFGISDYYGDIKWNMYMIGITDVWDYYYQYYGRYTFGRGVVVAVLDTGIDYTHPDLYGRVA
YCIRTTGSTTYRGTSLSNCMDRNGHGTHVAGIIAATINGAGVAGVAPNVTLIAVKVLYDSGSGSVTDIAEGIVEAVKAGA
YILSMSLGSSSDNSVLRDASNWAYQQGAIQIVAAGNSGDGNPSTDNVNYPARYPWVIAVAAVDSNGNTPSWSSDGPEVDV
AAPGVDILSTYLNKKYAYLSGTSMATPHVTGVVAVIEAMRYAAGKSWLGFDAIYKVLTSTAYDLGSSGFDVYTGYGLVDA
YSAVQYALSLP

Specific function: Has a broad substrate specificity with a slight preference to large hydrophobic amino acid residues at the P1 position [H]

COG id: COG1404

COG function: function code O; Subtilisin-like serine proteases

Gene ontology:

Cell location: Secreted [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S8 family [H]

Homologues:

Organism=Saccharomyces cerevisiae, GI6324576, Length=308, Percent_Identity=31.1688311688312, Blast_Score=110, Evalue=3e-25,
Organism=Saccharomyces cerevisiae, GI6320775, Length=317, Percent_Identity=31.2302839116719, Blast_Score=107, Evalue=4e-24,
Organism=Saccharomyces cerevisiae, GI6319893, Length=256, Percent_Identity=33.984375, Blast_Score=99, Evalue=2e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000209
- InterPro:   IPR022398
- InterPro:   IPR015500
- InterPro:   IPR009020 [H]

Pfam domain/function: PF00082 Peptidase_S8 [H]

EC number: NA

Molecular weight: Translated: 44143; Mature: 44143

Theoretical pI: Translated: 5.01; Mature: 5.01

Prosite motif: PS00136 SUBTILASE_ASP ; PS00137 SUBTILASE_HIS ; PS00138 SUBTILASE_SER

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVFNKYVLLIVLLALLLIPLVFSNESEALIVNGGSNKVRVVIGYRDESSRQNLLRNLGVS
CCCCHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCEEEEEEEECCCHHHHHHHHHCCCC
PVKEIRDLKVLVVEIPESLITRVKSLPGIRYIEKDIEARAFGISDYYGDIKWNMYMIGIT
HHHHHHCCEEEEEECCHHHHHHHHHCCCCHHHHHHHHHHEEECHHHCCCEEEEEEEEEHH
DVWDYYYQYYGRYTFGRGVVVAVLDTGIDYTHPDLYGRVAYCIRTTGSTTYRGTSLSNCM
HHHHHHHHHHCCEEECCCEEEEEEECCCCCCCCHHHHEEEEEEEECCCCEECCCCHHHHH
DRNGHGTHVAGIIAATINGAGVAGVAPNVTLIAVKVLYDSGSGSVTDIAEGIVEAVKAGA
CCCCCCCEEEEEEEEEECCCCCCCCCCCEEEEEEEEEEECCCCCHHHHHHHHHHHHHCCE
YILSMSLGSSSDNSVLRDASNWAYQQGAIQIVAAGNSGDGNPSTDNVNYPARYPWVIAVA
EEEEEECCCCCCCCHHHCCHHHHCCCCCEEEEEECCCCCCCCCCCCCCCCCCCCEEEEEE
AVDSNGNTPSWSSDGPEVDVAAPGVDILSTYLNKKYAYLSGTSMATPHVTGVVAVIEAMR
EECCCCCCCCCCCCCCEEEEECCCHHHHHHHHCCCEEEEECCCCCCCHHHHHHHHHHHHH
YAAGKSWLGFDAIYKVLTSTAYDLGSSGFDVYTGYGLVDAYSAVQYALSLP
HHCCCCCCCHHHHHHHHHHHHHHCCCCCCEEEECCCHHHHHHHHHHHHCCC
>Mature Secondary Structure
MVFNKYVLLIVLLALLLIPLVFSNESEALIVNGGSNKVRVVIGYRDESSRQNLLRNLGVS
CCCCHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCEEEEEEEECCCHHHHHHHHHCCCC
PVKEIRDLKVLVVEIPESLITRVKSLPGIRYIEKDIEARAFGISDYYGDIKWNMYMIGIT
HHHHHHCCEEEEEECCHHHHHHHHHCCCCHHHHHHHHHHEEECHHHCCCEEEEEEEEEHH
DVWDYYYQYYGRYTFGRGVVVAVLDTGIDYTHPDLYGRVAYCIRTTGSTTYRGTSLSNCM
HHHHHHHHHHCCEEECCCEEEEEEECCCCCCCCHHHHEEEEEEEECCCCEECCCCHHHHH
DRNGHGTHVAGIIAATINGAGVAGVAPNVTLIAVKVLYDSGSGSVTDIAEGIVEAVKAGA
CCCCCCCEEEEEEEEEECCCCCCCCCCCEEEEEEEEEEECCCCCHHHHHHHHHHHHHCCE
YILSMSLGSSSDNSVLRDASNWAYQQGAIQIVAAGNSGDGNPSTDNVNYPARYPWVIAVA
EEEEEECCCCCCCCHHHCCHHHHCCCCCEEEEEECCCCCCCCCCCCCCCCCCCCEEEEEE
AVDSNGNTPSWSSDGPEVDVAAPGVDILSTYLNKKYAYLSGTSMATPHVTGVVAVIEAMR
EECCCCCCCCCCCCCCEEEEECCCHHHHHHHHCCCEEEEECCCCCCCHHHHHHHHHHHHH
YAAGKSWLGFDAIYKVLTSTAYDLGSSGFDVYTGYGLVDAYSAVQYALSLP
HHCCCCCCCHHHHHHHHHHHHHHCCCCCCEEEECCCHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11375149 [H]