BacMap

Definition	Desulfurococcus kamchatkensis 1221n chromosome, complete genome.
Accession	NC_011766
Length	1,365,223

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The map label for this gene is hflB [C]

Identifier: 218884381

GI number: 218884381

Start: 1014025

End: 1016214

Strand: Reverse

Name: hflB [C]

Synonym: DKAM_1070

Alternate gene names: 218884381

Gene position: 1016214-1014025 (Counterclockwise)

Preceding gene: 218884382

Following gene: 218884380

Centisome position: 74.44

GC content: 45.39

Gene sequence:

>2190_bases
GTGAGAATAGTTTTAAAGGTCCTAGATGCTGATCGCAGGGATTATGGTAAGGGAATCGCCAGGCTCGACCCTGAGGTAAT
GGAGAAGTATGGTATAATGGATGGAGACCTATTACTCATCGAGGGTGATATGGAGGCTGCTGCGCTAGCTGGAAGCGGGA
ATACCCAGGATAGGGGTAAAGGTGTTATAAGGCTTGATCCATTGCTAAGACATAACGCTAGAGTTGAAATAGGGGATATA
GTGGTAGTTGAGAAAGTAGAGCGTAGATATGCTAAAGTAGTAAAACTAGCACCCACAAACTATCATGCCTTGATCGAGGG
TTATGTTTTAGAGAGTATAAGGAGTAAGTTGATAGGTTATCCCCTCATGGAGGACAATGAGATACAGGTCGTGATAGCTG
ATATGCCGATACCTTTCAAAGTAATCTCCATCAAGCCAAGAGGACCCGCACTAGTCTTTGATGAGACAGAGATATACGTC
TTCGAAGAACCAGTAGGCGAGTTTCCTCGCGTCACCTTTGAGGATATAGGTGGGCTTGGAAACATAATAGACAAGATTAG
AGAGATGATAGAGATACCATTGAAGTATAGAAAGGTATTCAGAAAACTTGGTATAGAGCCACCTAAGGGGATATTGCTCT
ACGGTCCACCAGGCACAGGTAAGACGCTGCTGGCTAAGGCTTTAGCTAACGAGGTTAACGCATACTTTGTAACTATTAAT
GGACCGGAGATAATGAGTAAGTACTATGGCGAATCCGAGCAACGATTACGCGAGATATTTAAGCTGGCTAAGAAGAAATC
GAGGAAGAACCCGGCTATAATATTCATCGATGAAATAGATGCGATAGCGCCTAAGAGAGATGAAGTAGTCGGAGAAGTAG
AGAGGAGAGTGGTGGCTCAGCTCCTCGCATTAATGGATGGGTTGGAGAGCAGGGGAAATGTAATAGTTATAGCGGCCACA
AACAGGCCTAACGCGTTAGATCCAGCTCTCAGAAGGCCTGGAAGATTTGACAGGGAGATCGAGATACCAATGCCGGATAA
AAAAGGCAGGCTCGAGATACTTCAGATACATACGCGGAGGCTCCGGGAACTCGGTATTCTCTCGGAGGATGTTGATCTAA
ATAAACTGGCTGAGATAACCCATGGATACACTGGTGCCGATCTAGCGGCATTGGTTAAGGAGGCAGTGCTCCATGCAATT
AGGAGGCAGATACCACTTGATCAACCCAGTGAATGGCCATTACCCGATGCCCTACTCACATCTATTAAAATCACCTTCGA
GGACTTCCTCTTTGCCTATAGGAGTATTGTACCAAGCGGCCTACGTGAAATACATGTTGAAGTACCAGATGTCAGGTGGA
GTGATATCGGGGGGCTTGAGGAGGTTAAGAGGTCTCTTAGGGAAAACGTTGAGCTGCCATTGAGATACCCGGAGATATAT
GAGAGATACGGGATAAAGCCTCCAAGAGGCGTTTTATTATACGGACCTCCTGGATGCGGTAAAACCTTGCTTGCGAAGGC
TGTTGCAACCGAGAGCGGGGCAAACTTCATAGCTGTCAAGGGTCCGGAGATAATGAGTAAATGGGTTGGAGAATCTGAGA
GAGCTATTAGAGAGATATTTAGGAAGGCTAGGCTCTATGCTCCAGTGGTAATATTCTTCGATGAGATAGATGCGATAGCA
TCCCTGAGGGGTATTGAAACGGATTCGGGTGCCTCAGAAAGGGTAGTTACACAGTTAATAACCGAGATGGACGGTATACA
GAAACTCGAAAACGTCGTCGTATTAGCTGCAACCAATAGGCCGGATCTCCTAGATCCAGCTTTACTGAGGCCTGGGAGAT
TCGATAAACTAATATATGTTCCACCCCCAGACTTCAATGCCAGGCTGGAAATACTTAGAATACATACTAGAAGTATACCT
TTGAGCAGGGATGTTAACCTAGTTGAACTGGCCAGAATTACTGAGGGCTATAGTGGAGCCGATTTAGAGGCGGTTGTGAG
GGAGACAGTTATGTTGGCGTTGAGGGGGTCTCCATTTATAGAGATGGTTGAGAGGAAGCATTTCATGAATGCTCTGGAGT
TAGTGAAGCCAAGTATAAATGATGCAATAATAAAATTCTATATTGAGTGGGGTAATAGAGCAAGGCAAACGCTTCCAAGA
CACGGTATTAAACCCAGTATATACACGTAG

Upstream 100 bases:

>100_bases
GTATTAGAAAGCTTTTTTACGGGTTTAAGAGAGTTAGTTCTACTAGGTGTTTTACCAGCTCTTTAACCATGGGAGAATTA
CTATATGGTGAAGCATATTG

Downstream 100 bases:

>100_bases
AGTAGTGGAAGTATTTTGGGTGATGTGCGGTATGACCAAGTATAATCCGGGATACTGGAGGATAACACCGCTCTTTAGAG
CTATATTGGAGGTGCTGGTG

Product: AAA family ATPase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 729; Mature: 729

Protein sequence:

>729_residues
MRIVLKVLDADRRDYGKGIARLDPEVMEKYGIMDGDLLLIEGDMEAAALAGSGNTQDRGKGVIRLDPLLRHNARVEIGDI
VVVEKVERRYAKVVKLAPTNYHALIEGYVLESIRSKLIGYPLMEDNEIQVVIADMPIPFKVISIKPRGPALVFDETEIYV
FEEPVGEFPRVTFEDIGGLGNIIDKIREMIEIPLKYRKVFRKLGIEPPKGILLYGPPGTGKTLLAKALANEVNAYFVTIN
GPEIMSKYYGESEQRLREIFKLAKKKSRKNPAIIFIDEIDAIAPKRDEVVGEVERRVVAQLLALMDGLESRGNVIVIAAT
NRPNALDPALRRPGRFDREIEIPMPDKKGRLEILQIHTRRLRELGILSEDVDLNKLAEITHGYTGADLAALVKEAVLHAI
RRQIPLDQPSEWPLPDALLTSIKITFEDFLFAYRSIVPSGLREIHVEVPDVRWSDIGGLEEVKRSLRENVELPLRYPEIY
ERYGIKPPRGVLLYGPPGCGKTLLAKAVATESGANFIAVKGPEIMSKWVGESERAIREIFRKARLYAPVVIFFDEIDAIA
SLRGIETDSGASERVVTQLITEMDGIQKLENVVVLAATNRPDLLDPALLRPGRFDKLIYVPPPDFNARLEILRIHTRSIP
LSRDVNLVELARITEGYSGADLEAVVRETVMLALRGSPFIEMVERKHFMNALELVKPSINDAIIKFYIEWGNRARQTLPR
HGIKPSIYT

Sequences:

>Translated_729_residues
MRIVLKVLDADRRDYGKGIARLDPEVMEKYGIMDGDLLLIEGDMEAAALAGSGNTQDRGKGVIRLDPLLRHNARVEIGDI
VVVEKVERRYAKVVKLAPTNYHALIEGYVLESIRSKLIGYPLMEDNEIQVVIADMPIPFKVISIKPRGPALVFDETEIYV
FEEPVGEFPRVTFEDIGGLGNIIDKIREMIEIPLKYRKVFRKLGIEPPKGILLYGPPGTGKTLLAKALANEVNAYFVTIN
GPEIMSKYYGESEQRLREIFKLAKKKSRKNPAIIFIDEIDAIAPKRDEVVGEVERRVVAQLLALMDGLESRGNVIVIAAT
NRPNALDPALRRPGRFDREIEIPMPDKKGRLEILQIHTRRLRELGILSEDVDLNKLAEITHGYTGADLAALVKEAVLHAI
RRQIPLDQPSEWPLPDALLTSIKITFEDFLFAYRSIVPSGLREIHVEVPDVRWSDIGGLEEVKRSLRENVELPLRYPEIY
ERYGIKPPRGVLLYGPPGCGKTLLAKAVATESGANFIAVKGPEIMSKWVGESERAIREIFRKARLYAPVVIFFDEIDAIA
SLRGIETDSGASERVVTQLITEMDGIQKLENVVVLAATNRPDLLDPALLRPGRFDKLIYVPPPDFNARLEILRIHTRSIP
LSRDVNLVELARITEGYSGADLEAVVRETVMLALRGSPFIEMVERKHFMNALELVKPSINDAIIKFYIEWGNRARQTLPR
HGIKPSIYT
>Mature_729_residues
MRIVLKVLDADRRDYGKGIARLDPEVMEKYGIMDGDLLLIEGDMEAAALAGSGNTQDRGKGVIRLDPLLRHNARVEIGDI
VVVEKVERRYAKVVKLAPTNYHALIEGYVLESIRSKLIGYPLMEDNEIQVVIADMPIPFKVISIKPRGPALVFDETEIYV
FEEPVGEFPRVTFEDIGGLGNIIDKIREMIEIPLKYRKVFRKLGIEPPKGILLYGPPGTGKTLLAKALANEVNAYFVTIN
GPEIMSKYYGESEQRLREIFKLAKKKSRKNPAIIFIDEIDAIAPKRDEVVGEVERRVVAQLLALMDGLESRGNVIVIAAT
NRPNALDPALRRPGRFDREIEIPMPDKKGRLEILQIHTRRLRELGILSEDVDLNKLAEITHGYTGADLAALVKEAVLHAI
RRQIPLDQPSEWPLPDALLTSIKITFEDFLFAYRSIVPSGLREIHVEVPDVRWSDIGGLEEVKRSLRENVELPLRYPEIY
ERYGIKPPRGVLLYGPPGCGKTLLAKAVATESGANFIAVKGPEIMSKWVGESERAIREIFRKARLYAPVVIFFDEIDAIA
SLRGIETDSGASERVVTQLITEMDGIQKLENVVVLAATNRPDLLDPALLRPGRFDKLIYVPPPDFNARLEILRIHTRSIP
LSRDVNLVELARITEGYSGADLEAVVRETVMLALRGSPFIEMVERKHFMNALELVKPSINDAIIKFYIEWGNRARQTLPR
HGIKPSIYT

Specific function: Seems To Act As An ATP-Dependent Zinc Metallopeptidase. Involved In The Degradation Of Sigma-32. Degrades Carboxy- Terminal-Tagged Cytoplasmic Proteins. These Proteins Are Tagged With An 11-Amino-Acid Nonpolar Destabilizing Tail VIa A Mechanism Involving

COG id: COG0464

COG function: function code O; ATPases of the AAA+ class

Gene ontology:

Cell location: Integral Membrane Protein. Inner Membrane [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the AAA ATPase family. CDC48 subfamily [H]

Homologues:

Organism=Homo sapiens, GI6005942, Length=735, Percent_Identity=44.3537414965986, Blast_Score=605, Evalue=1e-173,
Organism=Homo sapiens, GI157671927, Length=550, Percent_Identity=53.8181818181818, Blast_Score=575, Evalue=1e-164,
Organism=Homo sapiens, GI45643123, Length=594, Percent_Identity=44.6127946127946, Blast_Score=460, Evalue=1e-129,
Organism=Homo sapiens, GI45643125, Length=594, Percent_Identity=44.6127946127946, Blast_Score=459, Evalue=1e-129,
Organism=Homo sapiens, GI229577436, Length=748, Percent_Identity=36.3636363636364, Blast_Score=437, Evalue=1e-122,
Organism=Homo sapiens, GI4505725, Length=532, Percent_Identity=35.5263157894737, Blast_Score=298, Evalue=1e-80,
Organism=Homo sapiens, GI194018488, Length=522, Percent_Identity=35.632183908046, Blast_Score=264, Evalue=2e-70,
Organism=Homo sapiens, GI24497618, Length=280, Percent_Identity=46.0714285714286, Blast_Score=237, Evalue=2e-62,
Organism=Homo sapiens, GI153792536, Length=288, Percent_Identity=45.4861111111111, Blast_Score=236, Evalue=6e-62,
Organism=Homo sapiens, GI195539395, Length=302, Percent_Identity=42.7152317880795, Blast_Score=226, Evalue=7e-59,
Organism=Homo sapiens, GI24497435, Length=232, Percent_Identity=47.8448275862069, Blast_Score=225, Evalue=1e-58,
Organism=Homo sapiens, GI24430151, Length=302, Percent_Identity=42.0529801324503, Blast_Score=223, Evalue=5e-58,
Organism=Homo sapiens, GI5729991, Length=250, Percent_Identity=46.8, Blast_Score=218, Evalue=2e-56,
Organism=Homo sapiens, GI4506209, Length=271, Percent_Identity=43.5424354243542, Blast_Score=217, Evalue=2e-56,
Organism=Homo sapiens, GI24430155, Length=250, Percent_Identity=46.8, Blast_Score=217, Evalue=3e-56,
Organism=Homo sapiens, GI89064750, Length=250, Percent_Identity=46.8, Blast_Score=217, Evalue=3e-56,
Organism=Homo sapiens, GI156564401, Length=420, Percent_Identity=36.1904761904762, Blast_Score=213, Evalue=7e-55,
Organism=Homo sapiens, GI21361144, Length=231, Percent_Identity=45.021645021645, Blast_Score=208, Evalue=1e-53,
Organism=Homo sapiens, GI300192933, Length=252, Percent_Identity=44.047619047619, Blast_Score=206, Evalue=9e-53,
Organism=Homo sapiens, GI7019569, Length=234, Percent_Identity=44.017094017094, Blast_Score=201, Evalue=2e-51,
Organism=Homo sapiens, GI14149767, Length=300, Percent_Identity=41, Blast_Score=201, Evalue=2e-51,
Organism=Homo sapiens, GI62177112, Length=300, Percent_Identity=41, Blast_Score=201, Evalue=2e-51,
Organism=Homo sapiens, GI5901990, Length=250, Percent_Identity=46, Blast_Score=199, Evalue=8e-51,
Organism=Homo sapiens, GI310125280, Length=241, Percent_Identity=43.9834024896266, Blast_Score=185, Evalue=1e-46,
Organism=Homo sapiens, GI17865802, Length=236, Percent_Identity=41.5254237288136, Blast_Score=185, Evalue=2e-46,
Organism=Homo sapiens, GI310125282, Length=274, Percent_Identity=40.8759124087591, Blast_Score=184, Evalue=4e-46,
Organism=Homo sapiens, GI4507173, Length=231, Percent_Identity=42.4242424242424, Blast_Score=183, Evalue=4e-46,
Organism=Homo sapiens, GI226371754, Length=295, Percent_Identity=37.6271186440678, Blast_Score=179, Evalue=9e-45,
Organism=Homo sapiens, GI7657689, Length=240, Percent_Identity=40.8333333333333, Blast_Score=174, Evalue=2e-43,
Organism=Homo sapiens, GI21327685, Length=240, Percent_Identity=40.8333333333333, Blast_Score=174, Evalue=2e-43,
Organism=Homo sapiens, GI31742536, Length=284, Percent_Identity=33.0985915492958, Blast_Score=169, Evalue=1e-41,
Organism=Homo sapiens, GI112789543, Length=284, Percent_Identity=33.0985915492958, Blast_Score=169, Evalue=1e-41,
Organism=Homo sapiens, GI31377644, Length=230, Percent_Identity=38.695652173913, Blast_Score=167, Evalue=2e-41,
Organism=Homo sapiens, GI11875211, Length=345, Percent_Identity=33.6231884057971, Blast_Score=166, Evalue=1e-40,
Organism=Homo sapiens, GI40806170, Length=345, Percent_Identity=33.6231884057971, Blast_Score=166, Evalue=1e-40,
Organism=Homo sapiens, GI64084766, Length=286, Percent_Identity=32.5174825174825, Blast_Score=143, Evalue=7e-34,
Organism=Homo sapiens, GI40806173, Length=139, Percent_Identity=45.3237410071942, Blast_Score=113, Evalue=5e-25,
Organism=Homo sapiens, GI116292174, Length=265, Percent_Identity=30.188679245283, Blast_Score=111, Evalue=2e-24,
Organism=Homo sapiens, GI11321607, Length=197, Percent_Identity=28.9340101522843, Blast_Score=72, Evalue=1e-12,
Organism=Homo sapiens, GI40255052, Length=256, Percent_Identity=22.65625, Blast_Score=69, Evalue=2e-11,
Organism=Escherichia coli, GI1789568, Length=235, Percent_Identity=44.6808510638298, Blast_Score=205, Evalue=8e-54,
Organism=Caenorhabditis elegans, GI17532375, Length=736, Percent_Identity=42.7989130434783, Blast_Score=603, Evalue=1e-172,
Organism=Caenorhabditis elegans, GI17531535, Length=758, Percent_Identity=41.55672823219, Blast_Score=587, Evalue=1e-168,
Organism=Caenorhabditis elegans, GI17537217, Length=609, Percent_Identity=39.2446633825944, Blast_Score=395, Evalue=1e-110,
Organism=Caenorhabditis elegans, GI17508053, Length=536, Percent_Identity=37.1268656716418, Blast_Score=315, Evalue=7e-86,
Organism=Caenorhabditis elegans, GI193206116, Length=291, Percent_Identity=45.360824742268, Blast_Score=229, Evalue=3e-60,
Organism=Caenorhabditis elegans, GI193206114, Length=291, Percent_Identity=45.360824742268, Blast_Score=229, Evalue=4e-60,
Organism=Caenorhabditis elegans, GI133931034, Length=291, Percent_Identity=45.360824742268, Blast_Score=229, Evalue=4e-60,
Organism=Caenorhabditis elegans, GI71987364, Length=264, Percent_Identity=44.6969696969697, Blast_Score=222, Evalue=4e-58,
Organism=Caenorhabditis elegans, GI71987372, Length=264, Percent_Identity=44.6969696969697, Blast_Score=222, Evalue=5e-58,
Organism=Caenorhabditis elegans, GI17554786, Length=232, Percent_Identity=46.1206896551724, Blast_Score=221, Evalue=9e-58,
Organism=Caenorhabditis elegans, GI17562804, Length=474, Percent_Identity=32.4894514767932, Blast_Score=217, Evalue=1e-56,
Organism=Caenorhabditis elegans, GI17563248, Length=251, Percent_Identity=45.0199203187251, Blast_Score=215, Evalue=5e-56,
Organism=Caenorhabditis elegans, GI25144278, Length=231, Percent_Identity=45.8874458874459, Blast_Score=214, Evalue=1e-55,
Organism=Caenorhabditis elegans, GI25144281, Length=231, Percent_Identity=45.8874458874459, Blast_Score=214, Evalue=1e-55,
Organism=Caenorhabditis elegans, GI17563250, Length=291, Percent_Identity=39.5189003436426, Blast_Score=209, Evalue=3e-54,
Organism=Caenorhabditis elegans, GI25153574, Length=608, Percent_Identity=27.6315789473684, Blast_Score=207, Evalue=1e-53,
Organism=Caenorhabditis elegans, GI17508701, Length=231, Percent_Identity=42.4242424242424, Blast_Score=204, Evalue=1e-52,
Organism=Caenorhabditis elegans, GI17554784, Length=266, Percent_Identity=43.984962406015, Blast_Score=204, Evalue=2e-52,
Organism=Caenorhabditis elegans, GI17505546, Length=254, Percent_Identity=43.3070866141732, Blast_Score=198, Evalue=7e-51,
Organism=Caenorhabditis elegans, GI193209502, Length=210, Percent_Identity=44.7619047619048, Blast_Score=196, Evalue=3e-50,
Organism=Caenorhabditis elegans, GI86561515, Length=235, Percent_Identity=41.2765957446808, Blast_Score=185, Evalue=8e-47,
Organism=Caenorhabditis elegans, GI71994521, Length=263, Percent_Identity=41.8250950570342, Blast_Score=184, Evalue=2e-46,
Organism=Caenorhabditis elegans, GI133901662, Length=371, Percent_Identity=36.6576819407008, Blast_Score=183, Evalue=3e-46,
Organism=Caenorhabditis elegans, GI133901658, Length=371, Percent_Identity=36.6576819407008, Blast_Score=182, Evalue=6e-46,
Organism=Caenorhabditis elegans, GI17554264, Length=215, Percent_Identity=41.8604651162791, Blast_Score=170, Evalue=3e-42,
Organism=Caenorhabditis elegans, GI17508421, Length=279, Percent_Identity=39.7849462365591, Blast_Score=167, Evalue=2e-41,
Organism=Caenorhabditis elegans, GI32563584, Length=282, Percent_Identity=39.3617021276596, Blast_Score=166, Evalue=3e-41,
Organism=Caenorhabditis elegans, GI17560432, Length=279, Percent_Identity=36.2007168458781, Blast_Score=165, Evalue=1e-40,
Organism=Caenorhabditis elegans, GI17541226, Length=217, Percent_Identity=40.5529953917051, Blast_Score=164, Evalue=1e-40,
Organism=Caenorhabditis elegans, GI17541224, Length=217, Percent_Identity=40.5529953917051, Blast_Score=164, Evalue=1e-40,
Organism=Caenorhabditis elegans, GI115534323, Length=255, Percent_Identity=40.7843137254902, Blast_Score=159, Evalue=4e-39,
Organism=Caenorhabditis elegans, GI25146157, Length=287, Percent_Identity=36.5853658536585, Blast_Score=157, Evalue=1e-38,
Organism=Caenorhabditis elegans, GI71990294, Length=198, Percent_Identity=30.3030303030303, Blast_Score=72, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17570397, Length=105, Percent_Identity=37.1428571428571, Blast_Score=66, Evalue=7e-11,
Organism=Caenorhabditis elegans, GI32566590, Length=105, Percent_Identity=37.1428571428571, Blast_Score=66, Evalue=7e-11,
Organism=Saccharomyces cerevisiae, GI6320077, Length=750, Percent_Identity=43.3333333333333, Blast_Score=604, Evalue=1e-173,
Organism=Saccharomyces cerevisiae, GI6323429, Length=546, Percent_Identity=50.5494505494505, Blast_Score=523, Evalue=1e-149,
Organism=Saccharomyces cerevisiae, GI6322994, Length=619, Percent_Identity=40.3877221324717, Blast_Score=437, Evalue=1e-123,
Organism=Saccharomyces cerevisiae, GI6321709, Length=288, Percent_Identity=47.5694444444444, Blast_Score=252, Evalue=1e-67,
Organism=Saccharomyces cerevisiae, GI6324000, Length=439, Percent_Identity=35.9908883826879, Blast_Score=249, Evalue=1e-66,
Organism=Saccharomyces cerevisiae, GI6321390, Length=231, Percent_Identity=48.0519480519481, Blast_Score=229, Evalue=1e-60,
Organism=Saccharomyces cerevisiae, GI6322651, Length=483, Percent_Identity=32.0910973084886, Blast_Score=229, Evalue=1e-60,
Organism=Saccharomyces cerevisiae, GI6324833, Length=231, Percent_Identity=47.6190476190476, Blast_Score=219, Evalue=1e-57,
Organism=Saccharomyces cerevisiae, GI6320197, Length=230, Percent_Identity=46.5217391304348, Blast_Score=212, Evalue=2e-55,
Organism=Saccharomyces cerevisiae, GI6322704, Length=271, Percent_Identity=42.0664206642066, Blast_Score=212, Evalue=2e-55,
Organism=Saccharomyces cerevisiae, GI6319554, Length=411, Percent_Identity=37.2262773722628, Blast_Score=212, Evalue=2e-55,
Organism=Saccharomyces cerevisiae, GI6324691, Length=263, Percent_Identity=39.5437262357414, Blast_Score=199, Evalue=1e-51,
Organism=Saccharomyces cerevisiae, GI6320602, Length=238, Percent_Identity=44.5378151260504, Blast_Score=196, Evalue=8e-51,
Organism=Saccharomyces cerevisiae, GI6325431, Length=235, Percent_Identity=42.9787234042553, Blast_Score=193, Evalue=1e-49,
Organism=Saccharomyces cerevisiae, GI6323736, Length=250, Percent_Identity=42, Blast_Score=190, Evalue=6e-49,
Organism=Saccharomyces cerevisiae, GI6320854, Length=256, Percent_Identity=41.015625, Blast_Score=186, Evalue=2e-47,
Organism=Saccharomyces cerevisiae, GI6325281, Length=247, Percent_Identity=39.2712550607287, Blast_Score=181, Evalue=4e-46,
Organism=Saccharomyces cerevisiae, GI6325183, Length=303, Percent_Identity=34.6534653465347, Blast_Score=176, Evalue=2e-44,
Organism=Saccharomyces cerevisiae, GI6320887, Length=306, Percent_Identity=35.2941176470588, Blast_Score=164, Evalue=5e-41,
Organism=Saccharomyces cerevisiae, GI6321465, Length=235, Percent_Identity=39.5744680851064, Blast_Score=162, Evalue=2e-40,
Organism=Saccharomyces cerevisiae, GI9755327, Length=178, Percent_Identity=30.8988764044944, Blast_Score=75, Evalue=5e-14,
Organism=Saccharomyces cerevisiae, GI6320583, Length=149, Percent_Identity=32.2147651006711, Blast_Score=72, Evalue=2e-13,
Organism=Drosophila melanogaster, GI17137560, Length=746, Percent_Identity=43.5656836461126, Blast_Score=604, Evalue=1e-173,
Organism=Drosophila melanogaster, GI161076486, Length=746, Percent_Identity=43.5656836461126, Blast_Score=604, Evalue=1e-173,
Organism=Drosophila melanogaster, GI161076488, Length=736, Percent_Identity=44.0217391304348, Blast_Score=603, Evalue=1e-172,
Organism=Drosophila melanogaster, GI19921202, Length=563, Percent_Identity=41.2078152753108, Blast_Score=418, Evalue=1e-117,
Organism=Drosophila melanogaster, GI45552965, Length=310, Percent_Identity=47.741935483871, Blast_Score=283, Evalue=2e-76,
Organism=Drosophila melanogaster, GI281365776, Length=310, Percent_Identity=47.741935483871, Blast_Score=283, Evalue=3e-76,
Organism=Drosophila melanogaster, GI24660075, Length=310, Percent_Identity=47.741935483871, Blast_Score=283, Evalue=3e-76,
Organism=Drosophila melanogaster, GI24656825, Length=524, Percent_Identity=34.9236641221374, Blast_Score=265, Evalue=7e-71,
Organism=Drosophila melanogaster, GI24656820, Length=542, Percent_Identity=33.5793357933579, Blast_Score=258, Evalue=8e-69,
Organism=Drosophila melanogaster, GI21355121, Length=622, Percent_Identity=30.064308681672, Blast_Score=247, Evalue=2e-65,
Organism=Drosophila melanogaster, GI24652279, Length=259, Percent_Identity=44.4015444015444, Blast_Score=234, Evalue=1e-61,
Organism=Drosophila melanogaster, GI281363136, Length=505, Percent_Identity=33.6633663366337, Blast_Score=234, Evalue=2e-61,
Organism=Drosophila melanogaster, GI78707192, Length=505, Percent_Identity=33.6633663366337, Blast_Score=234, Evalue=2e-61,
Organism=Drosophila melanogaster, GI19920408, Length=232, Percent_Identity=47.8448275862069, Blast_Score=228, Evalue=1e-59,
Organism=Drosophila melanogaster, GI24651451, Length=231, Percent_Identity=48.0519480519481, Blast_Score=225, Evalue=1e-58,
Organism=Drosophila melanogaster, GI18860063, Length=237, Percent_Identity=48.1012658227848, Blast_Score=224, Evalue=2e-58,
Organism=Drosophila melanogaster, GI24640100, Length=253, Percent_Identity=47.0355731225296, Blast_Score=222, Evalue=7e-58,
Organism=Drosophila melanogaster, GI24649446, Length=291, Percent_Identity=41.5807560137457, Blast_Score=218, Evalue=1e-56,
Organism=Drosophila melanogaster, GI17137738, Length=249, Percent_Identity=45.3815261044177, Blast_Score=214, Evalue=2e-55,
Organism=Drosophila melanogaster, GI281361487, Length=237, Percent_Identity=45.1476793248945, Blast_Score=214, Evalue=2e-55,
Organism=Drosophila melanogaster, GI24663015, Length=261, Percent_Identity=43.2950191570881, Blast_Score=212, Evalue=9e-55,
Organism=Drosophila melanogaster, GI17738151, Length=248, Percent_Identity=42.741935483871, Blast_Score=210, Evalue=3e-54,
Organism=Drosophila melanogaster, GI24665814, Length=249, Percent_Identity=44.578313253012, Blast_Score=202, Evalue=8e-52,
Organism=Drosophila melanogaster, GI28574878, Length=249, Percent_Identity=44.578313253012, Blast_Score=202, Evalue=1e-51,
Organism=Drosophila melanogaster, GI24644145, Length=289, Percent_Identity=40.4844290657439, Blast_Score=197, Evalue=2e-50,
Organism=Drosophila melanogaster, GI28573010, Length=368, Percent_Identity=37.2282608695652, Blast_Score=197, Evalue=2e-50,
Organism=Drosophila melanogaster, GI17864540, Length=368, Percent_Identity=36.1413043478261, Blast_Score=193, Evalue=3e-49,
Organism=Drosophila melanogaster, GI24639391, Length=234, Percent_Identity=44.8717948717949, Blast_Score=190, Evalue=3e-48,
Organism=Drosophila melanogaster, GI18859657, Length=235, Percent_Identity=42.5531914893617, Blast_Score=190, Evalue=3e-48,
Organism=Drosophila melanogaster, GI24658770, Length=254, Percent_Identity=42.9133858267717, Blast_Score=189, Evalue=4e-48,
Organism=Drosophila melanogaster, GI281360144, Length=232, Percent_Identity=43.5344827586207, Blast_Score=187, Evalue=2e-47,
Organism=Drosophila melanogaster, GI281360140, Length=232, Percent_Identity=43.5344827586207, Blast_Score=187, Evalue=2e-47,
Organism=Drosophila melanogaster, GI281360136, Length=232, Percent_Identity=43.5344827586207, Blast_Score=187, Evalue=2e-47,
Organism=Drosophila melanogaster, GI24644411, Length=232, Percent_Identity=43.5344827586207, Blast_Score=187, Evalue=2e-47,
Organism=Drosophila melanogaster, GI281360146, Length=232, Percent_Identity=43.5344827586207, Blast_Score=187, Evalue=2e-47,
Organism=Drosophila melanogaster, GI281360138, Length=232, Percent_Identity=43.5344827586207, Blast_Score=187, Evalue=2e-47,
Organism=Drosophila melanogaster, GI281360142, Length=232, Percent_Identity=43.5344827586207, Blast_Score=187, Evalue=2e-47,
Organism=Drosophila melanogaster, GI21357333, Length=232, Percent_Identity=43.5344827586207, Blast_Score=187, Evalue=2e-47,
Organism=Drosophila melanogaster, GI20129529, Length=239, Percent_Identity=41.0041841004184, Blast_Score=175, Evalue=1e-43,
Organism=Drosophila melanogaster, GI24581396, Length=275, Percent_Identity=36, Blast_Score=172, Evalue=9e-43,
Organism=Drosophila melanogaster, GI20129423, Length=277, Percent_Identity=35.7400722021661, Blast_Score=171, Evalue=1e-42,
Organism=Drosophila melanogaster, GI28571849, Length=278, Percent_Identity=36.6906474820144, Blast_Score=159, Evalue=7e-39,
Organism=Drosophila melanogaster, GI28571847, Length=278, Percent_Identity=36.6906474820144, Blast_Score=159, Evalue=7e-39,
Organism=Drosophila melanogaster, GI24639486, Length=261, Percent_Identity=35.2490421455939, Blast_Score=143, Evalue=4e-34,
Organism=Drosophila melanogaster, GI45554047, Length=166, Percent_Identity=45.7831325301205, Blast_Score=142, Evalue=6e-34,
Organism=Drosophila melanogaster, GI28573181, Length=245, Percent_Identity=30.2040816326531, Blast_Score=82, Evalue=1e-15,
Organism=Drosophila melanogaster, GI20129417, Length=169, Percent_Identity=33.1360946745562, Blast_Score=74, Evalue=3e-13,
Organism=Drosophila melanogaster, GI24583262, Length=169, Percent_Identity=33.1360946745562, Blast_Score=74, Evalue=3e-13,
Organism=Drosophila melanogaster, GI221378492, Length=199, Percent_Identity=28.1407035175879, Blast_Score=71, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009010
- InterPro:   IPR003593
- InterPro:   IPR005938
- InterPro:   IPR003959
- InterPro:   IPR003960
- InterPro:   IPR003338
- InterPro:   IPR004201
- InterPro:   IPR015415 [H]

Pfam domain/function: PF00004 AAA; PF02933 CDC48_2; PF02359 CDC48_N; PF09336 Vps4_C [H]

EC number: 3.4.24.- [C]

Molecular weight: Translated: 81944; Mature: 81944

Theoretical pI: Translated: 6.83; Mature: 6.83

Prosite motif: PS00674 AAA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.1 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.1 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRIVLKVLDADRRDYGKGIARLDPEVMEKYGIMDGDLLLIEGDMEAAALAGSGNTQDRGK
CEEEEEECCCCCHHHCCCHHHCCHHHHHHHCCCCCCEEEEECCCCEEEEECCCCCHHHCC
GVIRLDPLLRHNARVEIGDIVVVEKVERRYAKVVKLAPTNYHALIEGYVLESIRSKLIGY
CEEEECHHHHCCCCEEECCEEEHHHHHHHHHHHEEECCCCHHHHHHHHHHHHHHHHHHCC
PLMEDNEIQVVIADMPIPFKVISIKPRGPALVFDETEIYVFEEPVGEFPRVTFEDIGGLG
CCCCCCCEEEEEECCCCCEEEEEECCCCCEEEEECCEEEEEECCCCCCCCCCHHHCCCHH
NIIDKIREMIEIPLKYRKVFRKLGIEPPKGILLYGPPGTGKTLLAKALANEVNAYFVTIN
HHHHHHHHHHHCCHHHHHHHHHHCCCCCCCEEEECCCCCCHHHHHHHHHCCCCEEEEEEC
GPEIMSKYYGESEQRLREIFKLAKKKSRKNPAIIFIDEIDAIAPKRDEVVGEVERRVVAQ
CHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCHHHHHHHHHHHHHHH
LLALMDGLESRGNVIVIAATNRPNALDPALRRPGRFDREIEIPMPDKKGRLEILQIHTRR
HHHHHHCCCCCCCEEEEEECCCCCCCCHHHHCCCCCCCEEECCCCCCCCCCHHHHHHHHH
LRELGILSEDVDLNKLAEITHGYTGADLAALVKEAVLHAIRRQIPLDQPSEWPLPDALLT
HHHHCCCCCCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHH
SIKITFEDFLFAYRSIVPSGLREIHVEVPDVRWSDIGGLEEVKRSLRENVELPLRYPEIY
HHHHHHHHHHHHHHHHHHCCHHEEEEECCCCCCCCCCCHHHHHHHHHCCCCCCCCCHHHH
ERYGIKPPRGVLLYGPPGCGKTLLAKAVATESGANFIAVKGPEIMSKWVGESERAIREIF
HHCCCCCCCCEEEECCCCCCHHHHHHHHHHCCCCCEEEECCHHHHHHHCCCHHHHHHHHH
RKARLYAPVVIFFDEIDAIASLRGIETDSGASERVVTQLITEMDGIQKLENVVVLAATNR
HHHHHHCCEEEEEHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHCCEEEEEECCC
PDLLDPALLRPGRFDKLIYVPPPDFNARLEILRIHTRSIPLSRDVNLVELARITEGYSGA
CCCCCHHHCCCCCCCCEEEECCCCCCCCEEEEEEEECCCCCCCCCCHHHHHHHHCCCCCC
DLEAVVRETVMLALRGSPFIEMVERKHFMNALELVKPSINDAIIKFYIEWGNRARQTLPR
CHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEHHCCHHHHHHHC
HGIKPSIYT
CCCCCCCCC
>Mature Secondary Structure
MRIVLKVLDADRRDYGKGIARLDPEVMEKYGIMDGDLLLIEGDMEAAALAGSGNTQDRGK
CEEEEEECCCCCHHHCCCHHHCCHHHHHHHCCCCCCEEEEECCCCEEEEECCCCCHHHCC
GVIRLDPLLRHNARVEIGDIVVVEKVERRYAKVVKLAPTNYHALIEGYVLESIRSKLIGY
CEEEECHHHHCCCCEEECCEEEHHHHHHHHHHHEEECCCCHHHHHHHHHHHHHHHHHHCC
PLMEDNEIQVVIADMPIPFKVISIKPRGPALVFDETEIYVFEEPVGEFPRVTFEDIGGLG
CCCCCCCEEEEEECCCCCEEEEEECCCCCEEEEECCEEEEEECCCCCCCCCCHHHCCCHH
NIIDKIREMIEIPLKYRKVFRKLGIEPPKGILLYGPPGTGKTLLAKALANEVNAYFVTIN
HHHHHHHHHHHCCHHHHHHHHHHCCCCCCCEEEECCCCCCHHHHHHHHHCCCCEEEEEEC
GPEIMSKYYGESEQRLREIFKLAKKKSRKNPAIIFIDEIDAIAPKRDEVVGEVERRVVAQ
CHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCHHHHHHHHHHHHHHH
LLALMDGLESRGNVIVIAATNRPNALDPALRRPGRFDREIEIPMPDKKGRLEILQIHTRR
HHHHHHCCCCCCCEEEEEECCCCCCCCHHHHCCCCCCCEEECCCCCCCCCCHHHHHHHHH
LRELGILSEDVDLNKLAEITHGYTGADLAALVKEAVLHAIRRQIPLDQPSEWPLPDALLT
HHHHCCCCCCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHH
SIKITFEDFLFAYRSIVPSGLREIHVEVPDVRWSDIGGLEEVKRSLRENVELPLRYPEIY
HHHHHHHHHHHHHHHHHHCCHHEEEEECCCCCCCCCCCHHHHHHHHHCCCCCCCCCHHHH
ERYGIKPPRGVLLYGPPGCGKTLLAKAVATESGANFIAVKGPEIMSKWVGESERAIREIF
HHCCCCCCCCEEEECCCCCCHHHHHHHHHHCCCCCEEEECCHHHHHHHCCCHHHHHHHHH
RKARLYAPVVIFFDEIDAIASLRGIETDSGASERVVTQLITEMDGIQKLENVVVLAATNR
HHHHHHCCEEEEEHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHCCEEEEEECCC
PDLLDPALLRPGRFDKLIYVPPPDFNARLEILRIHTRSIPLSRDVNLVELARITEGYSGA
CCCCCHHHCCCCCCCCEEEECCCCCCCCEEEEEEEECCCCCCCCCCHHHHHHHHCCCCCC
DLEAVVRETVMLALRGSPFIEMVERKHFMNALELVKPSINDAIIKFYIEWGNRARQTLPR
CHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEHHCCHHHHHHHC
HGIKPSIYT
CCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases); Metalloendopeptidases [C]

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9389475 [H]