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The map label for this gene is 218884229

Identifier: 218884229

GI number: 218884229

Start: 872486

End: 873631

Strand: Direct

Name: 218884229

Synonym: DKAM_0918

Alternate gene names: NA

Gene position: 872486-873631 (Clockwise)

Preceding gene: 218884227

Following gene: 218884231

Centisome position: 63.91

GC content: 46.6

Gene sequence:

>1146_bases
ATGACAAGCTACATGGATGTTGTTAAGGAAGTGGAGAAAATCCTATGGCCTAAACCCATGAAGCTATTCACAGCAGGACC
TGTTGCATGCTTTCCCGAAGTCCTTGAAGCCATGAAGATACAGCAATTAAGCCACAGGAGTAAGGAATACCAGGAATTAC
ACAAGGACACCGTTAAAAGGCTCGCCGACTTCCTCCTTGCTAGAAAAGCCACTGTTTTACTGATACCATCAAGTGGTACA
GGCTTCATGGAGGCTAGTGTGAGAAACGCTGTTACCCCTAGAGGTAAGGTGCTTGTAACAGTGATAGGTGAGTTCGGGAA
CAGGTATAAGGAGGCTGTTGAGAGGAATGGCAGGATACCAATAGTATTGGAGAAGCCGCTGGGTAAACCAGTCATACCAG
AAGAGCTGGATGACGCGCTAAAGAAGAACCCTGATGTAGAGGCAGTCACGATAACATATAATGAAACCAGTACAGGAGTA
TTAAACCCGTTGAAAGAGCTGGCCAAGGTGGTGAAGGAACATGGTAAACTACTCTTCGTTGACGCTGTTTCAGCTATGGG
TGCAGCTGATATCAGGGTGGATGAATGGGGCATAGACCTAGTCTTCGCCAGTAGCCAGAAAGCATTTGGTGTTCCCCCAG
GCCTCGCTATGGCTGCTGTAAGCGAGGAAGTATTTGAGAAAGCAAAAAAGATACCAGAGAGAGGACTATACTTTGACCTA
CTGGAGATAAAGGAGCTCCTTGAGAAACAGTGGTCTACGCCAACGACGCCACCAATTCCACAAATAGCAGGCCTCAACGT
CGCACTGAGAATAGTTGAGAAGATGGGTGGGAGAGAAGCATGGCTTAGAATGTATGCTGAGAGAGCTGAGAAGATTAGGA
GGGGTGTGCTGGAACTCGGCTTAAAACTCTTCGCAGAACCAGGCTATTATAGCCCTACAATAACAGTTATATATAATCCC
CCCGGAGTCAAGGGACCAGTGATATACGAGGAGCTTAGAAAGAGAGGCATTGAAATAGCTAAAGGATATGGTAAGGTGAA
AGACGAGACCTTCAGGATAGGACACATGGGCTATATAACCGAGAAGGATATAGAGGACTTATTCAGGAACCTGAAGGAGG
TACTTACAGCCGTCAGCAGGTTCTAA

Upstream 100 bases:

>100_bases
AGAGACGTACTGAGTTGATGATGTAGGTGGAGCGACTGGGACTCCTGAATAAACTATTTAACTAGGTTTTGACGATACCT
TTTCACATAGGTGTGAATAT

Downstream 100 bases:

>100_bases
ATTCTTTTTAAATATTTTTTGAACACGTTTTATTCTCTCGACATATCTACTCGTTTTCCTCGATGACTATTGCTTTTACT
TTTCTCCCGGTATTCTCTGG

Product: Aspartate/serine transaminase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 381; Mature: 380

Protein sequence:

>381_residues
MTSYMDVVKEVEKILWPKPMKLFTAGPVACFPEVLEAMKIQQLSHRSKEYQELHKDTVKRLADFLLARKATVLLIPSSGT
GFMEASVRNAVTPRGKVLVTVIGEFGNRYKEAVERNGRIPIVLEKPLGKPVIPEELDDALKKNPDVEAVTITYNETSTGV
LNPLKELAKVVKEHGKLLFVDAVSAMGAADIRVDEWGIDLVFASSQKAFGVPPGLAMAAVSEEVFEKAKKIPERGLYFDL
LEIKELLEKQWSTPTTPPIPQIAGLNVALRIVEKMGGREAWLRMYAERAEKIRRGVLELGLKLFAEPGYYSPTITVIYNP
PGVKGPVIYEELRKRGIEIAKGYGKVKDETFRIGHMGYITEKDIEDLFRNLKEVLTAVSRF

Sequences:

>Translated_381_residues
MTSYMDVVKEVEKILWPKPMKLFTAGPVACFPEVLEAMKIQQLSHRSKEYQELHKDTVKRLADFLLARKATVLLIPSSGT
GFMEASVRNAVTPRGKVLVTVIGEFGNRYKEAVERNGRIPIVLEKPLGKPVIPEELDDALKKNPDVEAVTITYNETSTGV
LNPLKELAKVVKEHGKLLFVDAVSAMGAADIRVDEWGIDLVFASSQKAFGVPPGLAMAAVSEEVFEKAKKIPERGLYFDL
LEIKELLEKQWSTPTTPPIPQIAGLNVALRIVEKMGGREAWLRMYAERAEKIRRGVLELGLKLFAEPGYYSPTITVIYNP
PGVKGPVIYEELRKRGIEIAKGYGKVKDETFRIGHMGYITEKDIEDLFRNLKEVLTAVSRF
>Mature_380_residues
TSYMDVVKEVEKILWPKPMKLFTAGPVACFPEVLEAMKIQQLSHRSKEYQELHKDTVKRLADFLLARKATVLLIPSSGTG
FMEASVRNAVTPRGKVLVTVIGEFGNRYKEAVERNGRIPIVLEKPLGKPVIPEELDDALKKNPDVEAVTITYNETSTGVL
NPLKELAKVVKEHGKLLFVDAVSAMGAADIRVDEWGIDLVFASSQKAFGVPPGLAMAAVSEEVFEKAKKIPERGLYFDLL
EIKELLEKQWSTPTTPPIPQIAGLNVALRIVEKMGGREAWLRMYAERAEKIRRGVLELGLKLFAEPGYYSPTITVIYNPP
GVKGPVIYEELRKRGIEIAKGYGKVKDETFRIGHMGYITEKDIEDLFRNLKEVLTAVSRF

Specific function: Unknown

COG id: COG0075

COG function: function code E; Serine-pyruvate aminotransferase/archaeal aspartate aminotransferase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI4557289, Length=367, Percent_Identity=26.158038147139, Blast_Score=123, Evalue=3e-28,
Organism=Caenorhabditis elegans, GI17536281, Length=350, Percent_Identity=26.8571428571429, Blast_Score=123, Evalue=2e-28,
Organism=Saccharomyces cerevisiae, GI6321079, Length=375, Percent_Identity=28.5333333333333, Blast_Score=117, Evalue=4e-27,
Organism=Drosophila melanogaster, GI17530823, Length=349, Percent_Identity=28.080229226361, Blast_Score=125, Evalue=3e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000192
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00266 Aminotran_5 [H]

EC number: 2.6.1.-

Molecular weight: Translated: 42610; Mature: 42479

Theoretical pI: Translated: 9.23; Mature: 9.23

Prosite motif: PS00595 AA_TRANSFER_CLASS_5

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTSYMDVVKEVEKILWPKPMKLFTAGPVACFPEVLEAMKIQQLSHRSKEYQELHKDTVKR
CCHHHHHHHHHHHHHCCCCCHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LADFLLARKATVLLIPSSGTGFMEASVRNAVTPRGKVLVTVIGEFGNRYKEAVERNGRIP
HHHHHHHCCCEEEEEECCCCCHHHHHHHHCCCCCCCEEEEEHHHHHHHHHHHHHCCCCEE
IVLEKPLGKPVIPEELDDALKKNPDVEAVTITYNETSTGVLNPLKELAKVVKEHGKLLFV
EEEECCCCCCCCHHHHHHHHHCCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHCCCEEEE
DAVSAMGAADIRVDEWGIDLVFASSQKAFGVPPGLAMAAVSEEVFEKAKKIPERGLYFDL
EHHHHCCCCCEEEECCCEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCHHH
LEIKELLEKQWSTPTTPPIPQIAGLNVALRIVEKMGGREAWLRMYAERAEKIRRGVLELG
HHHHHHHHHHCCCCCCCCCCCHHCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHH
LKLFAEPGYYSPTITVIYNPPGVKGPVIYEELRKRGIEIAKGYGKVKDETFRIGHMGYIT
HHHHCCCCCCCCEEEEEECCCCCCCCHHHHHHHHCCHHHHHCCCCCCCCEEEECCCCCCC
EKDIEDLFRNLKEVLTAVSRF
HHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
TSYMDVVKEVEKILWPKPMKLFTAGPVACFPEVLEAMKIQQLSHRSKEYQELHKDTVKR
CHHHHHHHHHHHHHCCCCCHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LADFLLARKATVLLIPSSGTGFMEASVRNAVTPRGKVLVTVIGEFGNRYKEAVERNGRIP
HHHHHHHCCCEEEEEECCCCCHHHHHHHHCCCCCCCEEEEEHHHHHHHHHHHHHCCCCEE
IVLEKPLGKPVIPEELDDALKKNPDVEAVTITYNETSTGVLNPLKELAKVVKEHGKLLFV
EEEECCCCCCCCHHHHHHHHHCCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHCCCEEEE
DAVSAMGAADIRVDEWGIDLVFASSQKAFGVPPGLAMAAVSEEVFEKAKKIPERGLYFDL
EHHHHCCCCCEEEECCCEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCHHH
LEIKELLEKQWSTPTTPPIPQIAGLNVALRIVEKMGGREAWLRMYAERAEKIRRGVLELG
HHHHHHHHHHCCCCCCCCCCCHHCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHH
LKLFAEPGYYSPTITVIYNPPGVKGPVIYEELRKRGIEIAKGYGKVKDETFRIGHMGYIT
HHHHCCCCCCCCEEEEEECCCCCCCCHHHHHHHHCCHHHHHCCCCCCCCEEEECCCCCCC
EKDIEDLFRNLKEVLTAVSRF
HHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]